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21 iul.

The Ovary’s Job Doesn’t End at Menopause: A Top Neuroscientist Explains

In this episode of unPAUSED, Dr. Mary Claire Haver talks with Dr. Jennifer Garrison, a neuroscientist and entrepreneur, about why the ovary should never have been labeled a purely reproductive organ. Dr. Garrison explains that ovaries function like a second brain in the body, sending and receiving chemical signals to nearly every tissue system including the heart, bones, brain, immune system, and metabolism. She walks through her research on the hypothalamus and the brain ovary signaling network, describing how inflammation in this part of the brain may be one of the earliest drivers of aging across the whole body. The conversation covers why the ovary ages roughly two and a half times faster than the rest of the body, a gap that helps explain the health span difference between women and men. Dr. Garrison and Dr. Haver discuss how poor ovarian function shows up across a woman's life, not only at menopause, contributing to conditions like polycystic ovarian syndrome, infertility, early menopause, depression, metabolic disease, and autoimmune disease. They also unpack why autoimmune conditions rise sharply after menopause and why women's immune systems respond differently to viruses than men's. Guest links: Jennifer Garrison, PhD (LinkedIn) Jennifer Garrison (X) Jennifer Garrison (Bluesky) Jennifer Garrison (X Prize)Jennifer Garrison (The Institute) Books “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause"⁠ by Dr. Mary Claire Haver For full show notes, please click here.
21 iul.

Emma Chamberlain On Building Chamberlain Coffee, Burnout & Walking Away From YouTube

Emma Chamberlain started posting videos at 16, before anyone fully understood what the creator economy would become. Within a couple of years she’d become one of the most watched people on YouTube with over 12 million subscribers, ambassador deals with Louis Vuitton, Cartier and Lancôme, and a Spotify-exclusive podcast. She helped define a new kind of fame, built one of the most recognizable personal brands of her generation, and turned an authentic love of coffee into Chamberlain Coffee, now sold in over 8,000 retail doors across Walmart, Target, Costco and Sprouts. Now, at 25, she’s asking a more complicated question: what happens when the business, and the person, need to grow beyond the identity that made them successful? Today, she’s answering why, after years of relentless momentum, she’s giving herself permission to step back and rediscover what actually fulfills her. In this episode, Emma shares: Why she moved into the co-CEO seat, and the fear that came with itThe real business story behind choosing profitability over growthWhat she’s learned about running a brand built around one personWhy she stepped away from her podcast at the height of itThe personal cost of giving an audience constant access to your lifeWhy she believes influencer culture is approaching a major shift
17 iul.

Lift Heavy, Protect Your Brain: Strength, Creatine, and Sauna for Women with Dr. Stacy Sims

In this episode of unPAUSED, Dr. Mary Claire Haver continues her conversation with exercise physiologist and nutrition scientist Dr. Stacy Sims, moving from what does not work to what actually does for women in perimenopause and menopause. They cover why strength training, not endless cardio, is one of the most powerful tools women have for protecting muscle, bone, and brain health at midlife, and Dr. Sims walks through exactly how to structure a 20 minute strength session for maximum benefit. The conversation turns to creatine, including why women between 18 and 65 see some of the strongest benefits for brain and heart health, proper dosing, and why timing and mixing matter for bioavailability. Dr. Sims and Dr. Haver also discuss why distance runners can still develop osteoporosis despite years of training, and how chronic under fueling and calcium loss play a role. Guest links: Dr. Stacy Sims Dr. Stacy Sims (Facebook) Dr. Stacy Sims (YouTube) Dr. Stacy Sims (Instagram) Stacy T. Sims, PhD (LinkedIn) Dr. Stacy Sims Newsletter Dr. Stacy Sims Microlearning Course Books “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause"⁠ by Dr. Mary Claire Haver “Next Level: Your Guide to Kicking Ass, Feeling Great, and Crushing Goals Through Menopause and Beyond,” by Dr. Stacy Sims “ROAR: How to Match Your Food and Fitness to Your Unique Female Physiology for Optimum Performance, Great Health, and a Strong, Lean Body for Life,” by Dr. Stacy Sims
6 iul.

Second Drink: Lecture Circuit, Pt 2

This week we finish breaking down Lecture Circuit. Pam and Michael make a detour to visit Holly at the Dunder Mifflin Utica branch only to encounter her new boyfriend, AJ. Angela Martin sold her engagement ring and bought a fancy cat, Princess Lady, and has to intervene with her other cats to make sure Princess Lady is bonding appropriately. We hear clips from guest star, Rob Huebel, on what it was like to play AJ, Angela gives us a breakdown of the cat licking scene and Jenna reveals who wrote the Holly letter she reads on Michael’s behalf. This episode is so good, you’re gonna ask for more “Office Ladies” at your work birthday, instead of an hour of napping or an hour of TV. After selling her engagement ring from Andy, Angela Martin buys Princess Lady, a fancy cat and gets very involved to make sure Princess Lady is bonding appropriately with her other cats Friend Zone with Rob Huebel and Paul Sheer: https://www.twitch.tv/friendzone The Fan Connection: https://www.fanconnectionmovie.com/the-fans Cat Tongue Pacifier Video: https://www.youtube.com/watch?v=N_beJnlTeTk Office Ladies Website - Submit a fan question: https://officeladies.com/submitaquestion Follow Us on Instagram: OfficeLadiesPod Follow Us on YouTube Follow Us on TikTok
3 feb.

Understanding Your Brain Through Perimenopause and Menopause with Dr. Louisa Nicola

An estimated 7.2 million Americans age 65 and older are currently living with Alzheimer's dementia. The part that should alarm every woman listening is this: almost two thirds of them are women. In this episode, Dr. Mary Claire Haver sits down with neurophysiologist and Alzheimer's researcher Dr. Louisa Nicola to unpack what's really happening to women's brains during perimenopause and menopause and what we can do about it. Louisa Nicola is a neurophysiologist, human performance coach, and founder of Neuro Athletics, a consulting firm that works with elite athletes and high-level professionals to optimize brain health and performance. A former world class triathlete, she transitioned into neuroscience and earned her Master of Medicine in neurophysiology from the University of Sydney. Dr. Nicola is currently pursuing her doctorate studying the effects of resistance exercise on brain health. She focuses on optimizing brain function and longevity, particularly in women, through sleep, nutrition, and exercise interventions. Dr. Nicola reveals how Alzheimer's disease doesn't suddenly appear at 70 but starts quietly in our thirties and forties, building up over a 30-year progression. She explains what's happening in the brain as amyloid beta proteins and tau tangles accumulate, why the hippocampus is the first area to go, and the critical role that sleep plays in clearing these proteins through the glymphatic system. The conversation explores why women are more predisposed to tau protein accumulation than men and how estrogen, progesterone, and prolactin inhibit the enzyme that causes tau proteins to become hyperphosphorylated and toxic. Dr. Nicola explains the connection between declining estrogen during perimenopause and increased Alzheimer's risk, including how estrogen helps mediate glucose metabolism in the brain, supports synaptic connections, and why the loss of this hormonal scaffolding leaves women vulnerable to cognitive decline. Guest links: Louisa Nicola (Instagram) Louisa Nicola (Facebook) Louisa Nicola, MMed, PhD(c) (LinkedIn) Louisa Nicola (YouTube) Louisa Nicola (X) Neuro Athletics The Neuro Experience Podcast (Apple Podcasts) The Brain Code Books“Joyspan,” by Dr. Kerry Burnight“The New Perimenopause,”⁠ by Dr. Mary Claire Haver ⁠"The New Menopause"⁠ by Dr. Mary Claire Haver p ...
26 mai

Gary Vaynerchuk: Why Truth, Humility, and Kindness Will Become Your Next Superpower

Gary Vaynerchuk has spent the last two decades understanding where culture and consumer behavior were headed long before the rest of the world caught up. He was early to YouTube, Twitter, TikTok, creator commerce, and live shopping. But this conversation is about more than algorithms and internet trends. In this episode, Gary sits down with Emma to talk about the real reason most people stay stuck: fear. Fear of judgment. Fear of failure. Fear of what other people will think if they try something new. Together, they unpack the insecurity driving modern ambition, why so many successful people are still deeply unhappy, and why Gary believes we are entering a cultural shift where kindness, reputation, and emotional intelligence will matter more than ever. Gary shares: Why most people are living for opinions they don’t even respect The hidden insecurity driving high achievement Why reputation compounds faster than money What social media actually revealed about human behavior How parents unintentionally destroy confidence in their kids Why proximity and visibility still matter in the AI era The business opportunities Gary believes people are still underestimating Why “nice guys finish first” What would change in your life if you stopped making decisions based on other people’s expectations of you? Drop it in the comments — we’re reading. And subscribe to Aspire with Emma Grede so you don’t miss what’s next. We'd love to hear what you think. Please take this survey to help us make the show better for you: ⁠emmagrede.com/survey
14 iul.

Why Women Gain Weight on the Same Diet as Men: Fueling, Fasting, and Biology with Dr. Stacy Sims

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with exercise physiologist and nutrition scientist Dr. Stacy Sims to unpack why so much fitness and diet advice built on male physiology leaves women confused about why the scale will not move, and why weight loss can feel so much harder for women than for men on the exact same plan. Dr. Sims, author of Roar and Next Level, a former professional cyclist who has taught and coached at Stanford, breaks down why women following the same diet and training program as their male partners often end up tired and stuck rather than leaner and fitter. The conversation covers the biological reasons women conserve fat in a calorie deficit, how female circadian rhythm differs from male circadian rhythm, and why eating within an hour of waking helps regulate cortisol and appetite hormones like ghrelin and peptide YY. Dr. Sims explains why fasted workouts can backfire for women, why front loading calories earlier in the day supports better metabolic outcomes, and why time restricted eating works with a woman's biology in ways that intermittent fasting often does not. Guest links: Dr. Stacy Sims Dr. Stacy Sims (Facebook) Dr. Stacy Sims (YouTube) Dr. Stacy Sims (Instagram) Stacy T. Sims, PhD (LinkedIn) Dr. Stacy Sims Newsletter Dr. Stacy Sims Microlearning Course Books “The New Perimenopause,” by Dr. Mary Claire Haver “The New Menopause"⁠ by Dr. Mary Claire Haver “Next Level: Your Guide to Kicking Ass, Feeling Great, and Crushing Goals Through Menopause and Beyond,” by Dr. Stacy Sims “ROAR: How to Match Your Food and Fitness to Your Unique Female Physiology for Optimum Performance, Great Health, and a Strong, Lean Body for Life,” by Dr. Stacy Sims
18.03.2019

35: Mexican-American War (Part 3): Nuevo México and the Final Push from Vera Cruz

“By God, that does looked forked!” This is the story of further American advancements through Northern Mexico and the start of its final invasion from the Gulf Coast. General Stephen Kearney’s descending upon New Mexico. He’ll take the territory without firing a shot, but that doesn’t mean violence isn’t coming. The Taos Revolt will lead to a beheaded American Governor and the execution of New Mexicans by an American regime of questionable legal authority. Meanwhile, Alexander Doniphan is marching south. He’s going to have some serious throwdowns, like the Battle of Sacramento. It’ll even interrupt his card game. At roughly the same time, Old Zack’s meager army of 5,000 is outnumbered 3 to 1 by Santa Anna at Buena Vista! Can Old Rough and Ready prevail? And finally, we have a new American commander on the scene: Winfield “Old Fuss and Feathers” Scott. He’s landing with a massive army at Mexico’s walled, artillery-laden, castle-protected, coastal city of Vera Cruz. So begins the last leg of the Mexican-American War. ____ Connect with us on HTDSpodcast.com and go deep into episode bibliographies and book recommendations join discussions in our Facebook community get news and discounts from The HTDS Gazette come see a live show get HTDS merch or become an HTDS premium member for bonus episodes and other perks.
30 iun.

Gut, Brain, and Hormones: The Menopause Connection with Dr. Amy Shah

In this episode of unPAUSED, Dr. Mary Claire Haver sits down with Dr. Amy Shah, a physician trained in internal medicine and immunology with a nutrition background from Cornell, and author of the new book Hormone Havoc. Dr. Haver and Dr. Shah begin the conversation with the gut-hormone-brain connection, explaining how 40% of estrogen is recirculated through the gut, how the estrobolome, the collection of gut bacteria responsible for metabolizing estrogen, determines how much the body retains, and why declining estrogen in perimenopause and menopause triggers a cascade that loosens the tight junctions meant to keep food particles, toxins, and viruses from entering the bloodstream. This leaky gut drives inflammation that accelerates every symptom women are already experiencing, from weight gain and mood changes to sleep disruption and brain health decline. The gut-brain axis, the constant two-way communication between the gut and the brain, means that what is happening in the gut is directly shaping cognitive function, motivation, and emotional resilience in menopause. She also covers how 95% of serotonin is made in the gut, why chronic inflammation reroutes tryptophan away from serotonin and melatonin, and what that means for mood, sleep, and appetite in midlife. Guest links: Dr. Amy Shah (Instagram) Dr. Amy Shah (TikTok) Dr. Amy Shah Save Yourself With Dr. Amy Shah (Apple Podcasts) Books: “Hormone Havoc: A Science-Backed Protocol for Perimenopause and Menopause: Sleep Better. Think Better. Feel Better,” by Dr. Amy Shah
3 mar.

How to Scale While Keeping Your Brand Intact (Kelly Wearstler)

Kelly Wearstler is one of the most influential designers in the world, but her real genius may be how she turned taste into a scalable multi-million dollar business. Over the years, she’s built a company that stretches far beyond interiors, expanding into product, licensing, creative direction, and media all while staying closely involved in the work itself. In this conversation, we get into the structure, decision-making, and resilience behind that growth. In this episode, Emma explores: How Kelly built a 60-person studio Why she believes in “sequence” over speed The commercial strategy behind creative work How she’s using AI within her company Investing in hierarchy and leadership Knowing when to walk away Why longevity matters more than hype This is a conversation about building something that evolves and making sure it’s designed to endure.

Audacy Podcasts is home to diverse voices that connect with audiences and influence conversation - from buzzy, pop culture juggernauts like The Severance Podcast to intimate storytelling from The Moth to widely-loved, personality-driven podcasts like Office Ladies. Audacy's slate of premium, hit shows and critically-acclaimed original series includes Fly on the Wall with David Spade and Dana Carvey, Gone South, Campus Files, What We Spend, Search Engine, Otherworld and The Tony Kornheiser Show - as well as network partners CBS News & Entertainment, CBS Sports, TenderfootTV, PAVE Studios, Puck News and Mythical Entertainment.

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