Infectious Disease Puscast

Vincent Racaniello
  • 5.0 (4)
  • Natural Sciences
  • Every two weeks

A review of the infectious diseases literature from the previous two weeks.

  1. 10 hr ago

    Infectious Disease Puscast

    On episode #114 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/18 – 8/31/26. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral HPV Vaccination and Risk of Head and Neck Cancers: A Large Real-World Cohort Study (International Society for Infectious Diseases) Beyond the Acute Illness: Three Myths About Viral RespiratoryInfection (JID) Use of Nowcasting to Estimate Real-Time Transmission Trends During a Measles Outbreak — South Carolina, October 2025–March 202 (CDC: MMWR) IPOL (Package Insert) Effect of inactivated poliovirus vaccine on nasal mucosal immunity and pharyngeal shedding following novel oral poliovirus vaccine type 2 challenge: A randomized, open-label trial (JID) Bacterial Response-Tailored or Standard-Duration Antibiotic Treatment for Infective Endocarditis (NEJM) Clinical Practice Guidelines by Infectious Diseases Society of America 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Introduction and Methods (CID) Society of America: 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections–Selection of Antibiotic Therapy for Complicated Urinary Tract Infections (CID) Clinical Practice Guidelines by Infectious Diseases Society of America: 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections – Timing of Intravenous to Oral Antibiotics Transition for Complicated Urinary Tract Infections (CID) Clinical Practice Guidelines by Infectious Diseases Society of America (IDSA): 2025 Guidelines on Management and Treatment of Complicated Urinary Tract Infections–Duration of Antibiotics for Complicated UTI (CID) Infective Endocarditis in Solid Organ and Haematopoietic Stem Cell Transplant Recipients (E-IPA Study): a propensity-score-matched retrospective cohort study (CID) Evaluation of Changes in Staphylococcus and Enterococcus Resistance Following Reduced Restrictions on Daptomycin and Linezoli (OFID) Comparison of VPM1002 with BCG in the prevention of tuberculosis in newborn infants: a multicentre, double-blind, randomised, phase 3, non-inferiority trial (LANCET: Infectious Diseases) Fungal The Last of US Season 2 (YouTube) Containment of a Candidozyma auris Outbreak in an Acute Care Hospital using a Comprehensive Screening and Surveillance Program (CID) Molecular Evidence of Autochthonous Environmental Acquisition of Fonsecaea Pediatric Infection in the United States (OFID) Challenging the concept of uncomplicated candidemia for shorter courses of antifungal therapy (OFID) Parasitic Miscellaneous Reliability of Physical Examination Findings in Youths Diagnosed With Pneumonia (JAMA) Recombinant shingles vaccination and the risk of cardiovascular events (Nature Medicine) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  2. 18 Aug

    Infectious Disease Puscast

    On episode #113 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 8/4 – 8/17/26. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Two-year durability of MVA-BN vaccine-induced antibodies and the risk of Mpox breakthrough infections among high-risk populations: a prospective, longitudinal study (CMI: Clinial Microbiology and Infection) Notes from the Field: Potential Infant HIV Exposure from Donated Breast Milk Received Through Social Media — Santa Clara County, California, May 2025–January 2026 (CDC: MMWR) Bacterial Associations Between QuantiFERON-TB Gold Plus IFNγ Concentrations and Progression to Symptomatic Tuberculosis in Global High-Burden TB Settings (OFID) Cefadroxil as Oral Transitional Therapy for Gram-Positive Bacteremia With or Without Non-Vertebral Osteomyelitis: A Multicenter Retrospective Cohort Study (OFID) Efficacy of beta-lactam monotherapy versus clindamycin or addition of metronidazole in peritonsillar abscess – an observational cohort study with a focus on Fusobacterium necrophorum (CMI: Clinial Microbiology and Infection) A novel RNA nucleic acid amplification test more accurately distinguishes active Clostridioides difficile infection from colonization (CID) The Clean Margin in Diabetic Foot Osteomyelitis: Conceptual Appeal, Practical Uncertainty (CID) Rising Incidence of New Delhi Metallo-β-Lactamase–Producing Carbapenem-Resistant Enterobacterales, 10 US Sites, 2018–2023 (OFID) Association of anti-anaerobic antibiotics with mortality and the gut microbiome: a sub-study of the BALANCE randomized clinical trial (CID) Fungal The Last of US Season 2 (YouTube) Coccidioidomycosis Testing Among Patients Hospitalized With Community-Acquired Pneumonia (OFID) Parasitic Human Myiasis Resulting from Reemergence of Cochliomyia hominivorax Screwworm, Mexico, 2025–2026 (Emerging Infectious Diseases) The origin, history, and resistance architecture of an invasive urban malaria mosquito in Africa (Science) Clinical, molecular, and in vitro evidence of artemisinin partial resistance in Ethiopian Plasmodium falciparum: a prospective, multisite, surveillance (LANCET: Infectious Diseases) Miscellaneous What's in a Name? Etymology and History of Antibacterials and Antifungal (IOFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  3. 5 Aug

    Infectious Disease Puscast

    On episode #112 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/20 – 8/3/26. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral The genomic identity of early smallpox in South America (Science) Telltale DNA: First direct evidence found that the Spanishbrought smallpox to the Inca (CIDRAP) Phase 3 Trial of Weekly Oral Islatravir–Lenacapavir for HIV-1 Treatment (NEJM) Early Transcriptional Signature in Chikungunya PredictsChronic Arthralgia and Reveals Deficient Antiviral Response (JID) Bacterial IDSA 2026 Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections (IDSA) Doxycycline in the treatment of outpatient mild community-acquired pneumonia: a propensity-matched retrospective cohort study (CMI: Clinical Microbiology and Infection) Detection of pathogens in the gut microbiome priorto bloodstream infection in children with acute myeloid leukemia or mature B-cell non-Hodgkin lymphoma (Journal of Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Active Surveillance for Invasive Mold Disease — Four Hospitals, Atlanta, Georgia, 2020–2024 (CDC: MMWR) Does the Evidence Support High-Dose Liposomal Amphotericin B in the Treatment of Mucormycosis? (JID) Miscellaneous Evaluation of the impact of a novel surgical handwashing method on reformation of microbial flora on surgeons' hands (Infection Control & Hospital Epidemiology) Association Between First MMR Vaccination Before Age 2 Years and Childhood Autism in a U.S. EHR Cohort of 2.5 Million Children (Journal of Pediatric Infectious Diseases Society) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  4. 23 Jul

    Infectious Disease Puscast

    On episode #111 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 7/7 – 7/20/26. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Impact of HIV-1 RNA Assay Selection on Low-Level Viremia and Clinical Trial Endpoint Interpretations (CID) Seroprevalence of Measles, Mumps, Rubella, and Varicella-Zoster Virus Antibodies—United States, 2017–March 2020 (JID) Concordance between nasopharyngeal swab and bronchoalveolar lavage PCR for respiratory viruses (CMI: Clinical Microbiology and Infection) Influenza vaccine effectiveness against outpatient acute respiratory illness with laboratory-confirmed influenza, United States, 2024–25 season (CID) Bacterial Clinical Impact of the BIOFIRE FILMARRAY Pneumonia Panel in the Veterans Affairs Healthcare System: A Difference-in-Differences Study (CID) Routine serial follow-up blood cultures after a negative result within 48 hours of methicillin-susceptible Staphylococcus aureus bacteremia: low yield, high cost (CID) Skipping to conclusions: Is one negative follow-up blood culture sufficient in Staphylococcus aureus bacteremia? (CID) Clinical Features of Clostridial Necrotizing Soft-Tissue Infections: Analysis of a Prospective Scandinavian Cohort Study(OFID) Fungal The Last of US Season 2 (YouTube) Molecular Epidemiology of Candidozyma auris Within a Case Cluster in North-Central Florida: Diverse Origins and Long-term Persistence ofStrain (OFID) Characteristics of Mortality in HIV-negative Cryptococcosis Patients: Analysis of a Cohort of 743 Patients (OFID) Parasitic Positive Strongyloides Serology: A Descriptive Analysis Across Geographically Distinct Academic Medical Centers (Transplant Infectious Diseases) Miscellaneous Community-acquired pneumonia: imperfect tests, imperfect clinicians or both? (CMI: Clinical Microbiology and Infection) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  5. 9 Jul

    Infectious Disease Puscast

    On episode #110 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 6/23 – 7/6/26. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Oseltamivir Resistance in Human Influenza A(H5N1) and A(H7N9) Infections: a mini review (OFID) Analysis of Viral Blips Through Week 192 of the DRIVE-FORWARD and DRIVE-AHEAD Phase 3 Studies of Doravirine-Based Regimens in Adults Living With Previously Untreated HIV-1 (OFID) Bacterial Impact of Multiplex PCR Blood-Culture Identification Panels on Clinical Outcomes, Antimicrobial Stewardship, and Economic Impact in US Hospitals: A Systematic Review and Meta-Analysis (OFID) Legionellosis Outbreaks Associated with Two Hotels — U.S. Virgin Islands, October 2024–April 2025 (CDC: MMWR) Impact of Methicillin Resistance on Outcomes of Staphylococcus aureus Bacteremia at a U.S. Center, 2023–2024 (OFID) Procalcitonin to Guide 7 vs 14 Days of Antibiotics in Bloodstream Infections (JAMA:Open Network) Fungal The Last of US Season 2 (YouTube) Comparing rapid molecular and culture methods for detecting fungal contamination in healthcare environments (Infection Control and Hospital Epidemiology) Surveillance for Candida auris — United States, 2022–2024 (CDC: MMWR) Parasitic Alpha-gal Immunoglobulin E Seroprevalence Among Blood Donors — 10 States, 2024–2025 (CDC: MMWR) Schistosomiasis vaccine SchistoShield induces functional immune memory responses in US and African populations (njp: Vaccines) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  6. 24 Jun

    Infectious Disease Puscast

    On episode #109 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/4 – 6/22/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral CMV viraemia is associated with mortality among children with HIV starting antiretroviral therapy in sub-Saharan Africa (CID) Bacterial Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia(NEJM) A fatal case of Legionella micdadei prosthetic valve endocarditis diagnosed by plasma microbial cell-free DNA metagenomic sequencing (LANCET: Infectious Diseases) Legionnaires Disease Associated with a Private-Use Hot Tub in a Vacation Rental Property — New York, October 2024–April 2025 (CDC: MMWR) Notes from the Field: Case of Legionnaires Disease Associated with a Home Device Used to Mix Powdered Infant Formula — United States, 2025 (CDC:MMWR) Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCErandomized clinical trial (CMI: Clinical Microbiology and Infection) FDA approves first oral carbapenem therapy for complicated urinary tract infections (FDA) Oral Tebipenem Matched IV antibiotic for complicated UTIs in Phase III Trial (MEDPAGE Today) US FDA approves GSK's oral antibiotic for drug-resistant UTIs (Reuters) Anti–Methicillin-Resistant Staphylococcus aureus (MRSA) Cephalosporins Plus Daptomycin as Initial Therapy for MRSA Bacteremia: Does a "Hit Hard and Fast" Strategy Improve Outcomes? (CID) Fungal The Last of US Season 2 (YouTube) Oral Wash PCR Improves the Diagnosis of Pneumocystis Pneumonia in Immunocompromised Patients Without HIV: A Prospective Multicenter Study (CID) Miscellaneous Foodborne Disease Outbreaks Associated with Marine Toxins — Foodborne Disease Outbreak Surveillance System, United States, 2011–2023 (CDC: MMWR) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  7. 11 Jun

    Infectious Disease Puscast

    On episode #108 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/21 – 6/3/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Performance of five mpox antigen-based rapid diagnostic tests tested on lesion swabs from patients with suspected mpox from the Kinshasa province of DR Congo: a diagnostic accuracy study (LANCET: Infectious Diseases) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D (NEJM) First reported case of Andes hantavirus cardiopulmonary syndrome treated with a combination of favipiravir, ribavirin, icatibant and baricitinib (CMI: Clinical Microbiology and Infection) Chikungunya Vaccines for Travelers: Unanswered Pragmatic Questions Persist (JID) Bacterial Early Discontinuation of Empiric Antibiotics in Pediatric Haploidentical Hematopoietic Cell Transplant Recipients with Febrile Neutropenia (CID) Methicillin-Resistant Staphylococcus aureus Nasal Swab Utilization as a Predictor for Methicillin-Resistant Staphylococcus aureus Skin and Soft Tissue Infections: A Systematic Review and Meta-analysis (OFID) Swab Testing to Optimize Pneumonia Treatment With Empiric Vancomycin: A Randomized Controlled Trial (CID) Fungal The Last of US Season 2 (YouTube) Donor-derived and nosocomial-acquired Candida auris transmission involving solid organ transplant recipients (Infection Control and Hospital Epidemiology) Parasitic Development of a Phase 1 Cryptosporidiosis Controlled Human Challenge Model in Healthy Volunteers Using Current Good Manufacturing Practice Cryptosporidium Parvum Oocysts and Conducted Under an Investigational New Drug Application (JID) Miscellaneous Childhood VaccineHesitancy(NEJM) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

  8. 29 May

    Infectious Disease Puscast

    On episode #107 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/7 – 5/20/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral FDA Grants Accelerated Approval to Gilead's Hepcludex® (bulevirtide-gmod), the First and Only Approved Treatment for Chronic Hepatitis Delta Virus (HDV) (Gileadl) A Phase 3, Randomized Trial ofBulevirtide in Chronic Hepatitis D(NEJM) Study to Assess Efficacy and Safety of Bulevirtide in Participants With Chronic Hepatitis Delta (CHD) (NLM: ClinicalTrials.gov) Andes Hantavirus Outbreak on a Cruise Ship, 2026 (NEJM) Quick takes: Another hantavirus case, polio in 3 countries, NIAID head steps down (CIDRAP) Dolutegravir Reduces Human T-Cell Lymphotropic Virus Type 1 Proviral Load and Improves Neurological Outcomes in a Phase 2 Controlled Trial (CID) Dolutegravir Appears to Lower Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) Proviral Load: The Emerging Rational Approach to Treatment of HTLV-1–Associated Myelopathy (CID) Use of Dolutegravir for treatment of HTLV-1 (CID) Use of dolutegravir to treat people living with HTLV-1-associated myelopathy (HAM) (CID) Bacterial Urinary Tract Infection (UTI)-free and Recurrent UTI (rUTI)-Free Survivals Following Bladder Electrofulguration in Women With a History of Antibiotic-Refractory rUTI (OFID) Azithromycin for Preschoolers with Wheezing in the Emergency Department (JAMA) Rapid Respiratory Microbiological Point-of-Care Testing and Antibiotic Use in Primary Care (JAMA Internal Medicine) Fungal The Last of US Season 2 (YouTube) Changes in Epidemiology of Candidemia in the United States With a Focus on Candida auris (CID) Parasitic Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme (The LANCET) Ivermectin-Benzimidazole Prescribing Following Celebrity Endorsement  (JAMA Network OPEN) Febrile Temperature Augents Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells (JID) An Increase in Imported Plasmodium vivax Malaria in New York City: Clinical and Demographic Trends Following Recent Migration (OFID) Miscellaneous The State of Physician Leadership (WittkKieffer) Infectious Diseases Fellowship Curriculum: IDSA Training Program Directors Community of Practice (TPDCOP), Curricular and Educational REsources Workgroup (CREW) (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

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A review of the infectious diseases literature from the previous two weeks.

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