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What's happening in the clinical lab community including publications in JMSACL and interviews with the Early Career Network.

  1. 2023-11-14

    The Regulatory Landscape of Laboratory Developed Tests (LDT): A Laboratorian Perspective

    The FDA released a proposed LDT rule and stated it will “end its enforcement discretion” of LDTs. Previously, the FDA explored other avenues for regulating LDTs. We will discuss questions relevant to the draft rule and implications to laboratory medicine, including, but not limited to: - What are possible implications of FDA regulation of LDTs? - Is the FDA the appropriate mechanism for this LDT oversight? - What about modernization of CLIA? - What would be the financial cost? - What would be the diagnostic cost?

    57 min
  2. MSACL 2023 : A Chat with Jennifer Van Eyk on her Distinguished Contribution Award Lecture

    2023-04-05

    MSACL 2023 : A Chat with Jennifer Van Eyk on her Distinguished Contribution Award Lecture

    Dustin Bunch chats with Jennifer Van Eyk on the fine points of her Distinguished Contribution Award lecture from the previous evening. Recorded onsite at MSACL 2023 Monterey in the Exhibit Hall.

    12 min
  3. MSACL 2023 : A Chat with Tim Collier on his Michael S Bereman Award Lecture

    2023-04-05

    MSACL 2023 : A Chat with Tim Collier on his Michael S Bereman Award Lecture

    Dustin Bunch chats with Tim Collier on some of the nuances of his Michael S Bereman Award for Innovative Clinical Proteomics lecture from the previous afternoon. Recorded onsite at MSACL 2023 Monterey in the Exhibit Hall.

    12 min
  4. The MetaProteomics Initiative : The Cornerstone of Comprehensive Molecular Analysis of the Microbiome Ecosystem

    2023-03-16

    The MetaProteomics Initiative : The Cornerstone of Comprehensive Molecular Analysis of the Microbiome Ecosystem

    Through connecting genomic and metabolic information, metaproteomics is an essential approach for understanding how microbiomes function in space and time. The international metaproteomics community is delighted to announce the launch of the Metaproteomics Initiative (www.metaproteomics.org), the goal of which is to promote dissemination of metaproteomics fundamentals, advancements, and applications through collaborative networking in microbiome research.

    42 min
  5. Paper Spray Mass Spectrometry in Clinical Application

    2022-12-15

    Paper Spray Mass Spectrometry in Clinical Application

    An interview with Lindsey Kirkpatrick, DO, PhD and Nicholas Manicke, PhD discussing the technology behind, and development of, Paper Spray technology, as well as its place in the clinical lab. Read the companion article in JMSACL, Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma (https://doi.org/10.1016/j.jmsacl.2022.06.001).

    35 min
  6. The triple quadrupole: Innovation, serendipity and persistence

    2022-11-02

    The triple quadrupole: Innovation, serendipity and persistence

    An interview with Richard Yost, co-developer of the Triple Quadrupole Mass Spectrometer. How it was developed and why. Read the companion article in JMSACL at https://www.sciencedirect.com/science/article/pii/S2667145X22000141

    43 min
  7. JMSACL Journal Club : Supervised Machine Learning for Mass Spectrometry Data Analysis: Experts' Opinion

    2022-03-01

    JMSACL Journal Club : Supervised Machine Learning for Mass Spectrometry Data Analysis: Experts' Opinion

    We will be talking with Thomas Durant and Edward Lee about recent advances in machine learning (ML) for mass spectrometry (MS) data analysis. The primary focus will be the alignment of these two fields (ML and MS) and how this offers a promising synergy that can be used to optimize workflows, improve result quality, and enhance our understanding of high-dimensional datasets, as well as their inherent relationship with disease biology. We will also dig deeper to understand a basic overview of ML and an ML-based experiment. Overall, we will have a opportunity go through the fundamental principles of supervised ML, outline the steps that are classically involved in an ML-based experiment, and discuss the purpose of good ML practice in the context of a binary MS classification problem.

    59 min
  8. Fireside Chat with Christopher Rose on Single Cell Proteomics

    2021-09-29

    Fireside Chat with Christopher Rose on Single Cell Proteomics

    Christopher Rose shares his thoughts on single cell proteomics.

    1 tim 3 min
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What's happening in the clinical lab community including publications in JMSACL and interviews with the Early Career Network.

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  • Skapad av
    MSACL
  • Aktiva år
    2021 - 2023
  • Avsnitt
    19
  • Åldersgräns
    Barnvänligt
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    © 2021 MSACL
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