This Week in Startups

Jason Calacanis
This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

  1. 1 DAY AGO

    Lovable's Anton Osika on Revolutionizing Software Development and OpenAI Drops Deep Research | E2080

    OpenAI dropped Deep Research—hilariously, the exact same name as Google’s existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev’s insane growth to $10M ARR in weeks, and test whether AI can really replace software engineers. Plus, they analyze Trump’s latest tariff chaos and what it means for startups, global trade, and the economy. * Timestamps: (0:00) Jason and Alex kick off the show. (1:09) Jason’s talk and case study at Stanford (2:38) Managing the chaotic news cycle (5:22) NBA trade insights: Luka Doncic and Anthony Davis (7:15) Lovable startup's rapid growth (9:44) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (11:02) Lovable's AI demo and European startup landscape (15:20) Lovable's target market and pricing strategy (19:48) PrizePicks. Run your game. Download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST (21:39) Custom software development's future with AI (23:17) Launching and designing AI-powered apps (27:07) US sovereign wealth funds and crypto regulation (28:56) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups (33:42) Creative tax and debt reduction strategies (41:34) Defense spending and OpenAI's new product (46:51) OpenAI's market impact and ethical considerations (53:02) AI's role in content creation and job market (58:13) Venture capital trends and startup ecosystem (1:01:19) DeepSeek's popularity and security concerns (1:03:28) Tariffs, economic impact, and supply chain importance * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp * Check out: Standford Case Study on Jason: https://www.gsb.stanford.edu/faculty-research/case-studies/jason-calacanis-case-study-creating-resources OpenAI’s Deep Research: https://openai.com/index/introducing-deep-research/ * Follow Anton X: https://x.com/antonosika LinkedIn: https://www.linkedin.com/in/antonosika/ * Follow Lovable: X: https://x.com/lovable_dev Website: www.lovable.dev * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (0:00) Lemon.io. Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (0:00) PrizePicks. Run your game. Download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST (0:00) LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1h 7m

  2. 4 DAYS AGO

    Is OpenAI Really Worth $300B? ElevenLabs’ Series C & YC’s Funding Focus | E2079

    Today’s show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI’s sky-high valuation, the surprising rise of DeepSeek’s R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the latest on AI hardware, antitrust battles, and why the “No Buy 2025” trend could change how we think about consumer tech. * Timestamps: (0:00) Jason and Alex kick off the show. (3:10) Episode topics overview and fan participation (5:48) Meta's Ray-Ban smart glasses discussion (9:27) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period. (11:05) 11 Labs' Series C funding and voice cloning technology (18:09) Automation's impact on jobs and ethical considerations (20:05) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist today. (21:22) Market trends towards sustainability and AI in smart chicken coops (27:04) Y Combinator's AI startup focus and investment considerations (29:47) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist (31:42) AI in compliance, auditing, and personal staff replacement (35:06) AI development tools, hardware investments, and data trust issues (39:29) AI company valuations, OpenAI's revenue, and AI commoditization (51:04) AI ethics, SoftBank's strategy, and audience questions on AI hardware (59:27) Government AI funding, DOJ suit, and tech industry commoditization (1:09:21) AI advancements, consumer electronics costs, and computing hardware trends (1:12:08) Closing thoughts on technology's impact on life and teaser for next week * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (9:27) Paddle. Go to https://www.paddle.com/twist to get started with your exclusive listener fee-free period. (20:05) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (29:47) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1h 13m

  3. 6 DAYS AGO

    Boom Supersonic's Milestones, OpenAI Ethics, and Startup Tools | E2078

    This Week in Startups is brought to you by… Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://northwestregisteredagent.com/twist⁠ today. Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist Today’s show: Jason and Alex cover Jason’s unique sauna experience, leading them to discuss the value of niche communities and supporting small startups, spotlighting Boom Supersonic's achievements and Starlink's aviation collaborations. Financial updates include the Federal Reserve's actions and Trump's public opinion. They analyze the impact of CapEx on tech giants and Meta's AR/VR success. The DeepSeek controversy, OpenAI's intellectual property issues, and AI race risks and opportunities are explored. Jason and Alex conclude with insights on building startups and modern tools for entrepreneurs. Timestamps: (0:00) Episode Teaser (1:39) Introduction to the podcast; Jason's sauna experience; GoPolar app (3:41) Niche communities; encouraging small startup projects (10:11) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist (13:48) Boom Supersonic's achievements and flight details (18:30) Starlink's role in aviation; Apple collaboration; Helium project (20:47) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist⁠ today. (24:11) Financial updates; Federal Reserve; Trump's public opinion (30:14) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist (31:57) Federal spending; debt strategies; upcoming tech earnings (37:18) Impact of CapEx on tech giants; Meta's AR/VR success (42:26) DeepSeek controversy; OpenAI's response and IP issues (50:13) AI race risks and opportunities; OpenAI's market position (57:13) Building startups; Founder University; modern tools for startups (1:02:15) Closing remarks; upcoming episodes Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out: Boom Supersonic: https://boomsupersonic.com/ GoPolar App: https://www.gopolar.app/ Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (10:11) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist (20:47) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit ⁠https://www.northwestregisteredagent.com/twist today. (30:14) Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1h 3m

  4. 27 JAN

    DeepSeek Rattles Markets + SailPoint's Going Public… again? | E2077

    Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity’s “buy, fix, and flip” strategy? Don’t miss this deep dive into the latest tech and startup news! * Timestamps: (0:00) Jason and Alex kick off the show. (1:58) DeepSeek's market impact and Project Stargate (4:18) Innovation, H100 GPUs, and open-source AI models (8:41) Jevons paradox, Pat Gelsinger's analogy, and AI efficiency (10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (13:25) AI's benefits for startups and privacy concerns (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (19:51) AI optimization vs. hardware consumption (22:20) OpenAI's revenue, valuation, and NVIDIA's market value (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist (33:21) Unified AI digital assistants and DeepSeq's new model (35:01) AI's role in venture capital and team size reduction (41:04) China's influence and DeepSeek's market impact (43:22) Startup shutdowns and potential for increased M&A activity (53:02) Nvidia's historical analysis, risks of leverage, and SailPoint's IPO * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (10:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (19:32) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:13) LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1 hr

  5. 24 JAN

    Twilio Bets Small, DeepSeek Scares & the GameOn Fraud | E2076

    This Week in Startups is brought to you by… Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Twilio’s team size compression, DeepSeek’s scary good AI for only $6M and the GameOn fraud saga that sounds too crazy to be true. Timestamps: (0:00) Alex and Jason kick off the show (6:27) Rundown of potential topics (7:10) Twilio's team size strategy and AI's impact on workforce (9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (14:52) Entrepreneurship in the AI era and automation concerns (19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (22:49) Meta's investment in data centers and surplus compute power (26:36) Technology’s potential to solve humanity’s problems (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. (32:01) Empathy for workers displaced by automation (34:11) DeepSeq's role in reducing AI industry costs (37:27) Game On startup fraud case and due diligence in startups (53:13) Venture capital's role in startup oversight (55:36) OpenAI's Operator announcement and AI autonomy risks Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (9:40) Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST (19:30) Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST (30:12) Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    58 min

  6. 23 JAN

    Created By Humans | Sila’s Battery Evolution | E2075

    This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Today’s show: Alex covers The Stargate Project, other hot news items, and two great interviews. Created By Humans’ Co-founder Trip Adler talks about the future of copyrights and AI. Gene Berdichevsky, Co-founder and CEO of Sila, discusses the future of batteries and our clean energy future. Timestamps: (0:00) Alex kicks off the show. (1:22) Introduction to Mistral's IPO, Anthropic's funding, and Project Stargate (6:01) Market reactions and AI funding landscape (10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist (11:35) Tripp Adler discusses AI in literature and Created by Humans (16:20) Authors' concerns and AI companies' reactions (19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist (20:58) Tripp Adler on AI, copyright, and the future of authorship (27:47) Human-created content symbol and synthetic vs. human data (29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. (34:08) Gene Berdichevsky on Sila's battery technology and Titan Silicon anodes (41:29) Battery tech's role in industry transformation and consumer devices (48:25) The impact on renewable energy and grid storage (53:02) Hard tech challenges, fundraising, and IPO considerations (56:38) Netflix's quarterly earnings and tech market forecasts Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out: Created by Humans: Website: https://www.createdbyhumans.ai/ X: https://x.com/createdbyhumans Follow Trip: X: https://x.com/tripadler LinkedIn: https://www.linkedin.com/in/tripadler/ Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: (10:19) Gusto. Get three months free when you run your first payroll at http://gusto.com/twist (19:42) Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist (29:52) Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    59 min

  7. 21 JAN

    Trump, Memecoins, and What to Expect from the New Administration | E2074

    Today’s show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen X's rising political power, tech CEOs' prominence at inaugurations, and critique Democrats' tech policies. The conversation covers economic factors in elections, like inflation and abortion rights, COVID's origins, immigration policy, and foreign policy. AI regulation under Biden and Trump's economic strategies, including crypto regulations, are debated. They also discuss Trump's impact on M&A, antitrust laws, and the startup ecosystem, with insights on tech IPOs and tax policy. * Timestamps: (0:00) Jason and Alex kick off the show. (1:06) Diving into recent DC events and tech's political role (3:13) Gen X's rising political influence and tech CEOs' prominence at inauguration (7:00) Discussion on tech founders' importance and criticism of Democrats' tech stance (10:17) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (11:35) Economic factors influencing elections: Inflation and abortion rights (17:15) COVID origins investigation and executive orders affecting tech (19:58) OpenPhone. TWiST listeners can get 20% off your first 6 months at https://openphone.com/twist (21:25) Steve Bannon, JD Vance, and immigration policy discussions (23:20) US potential territory expansion and foreign policy (30:23) LinkedIn Jobs. TWiST listeners can post their first job for free at https://www.linkedin.com/twist (32:13) Trump's economic strategies, legacy, and US energy production (41:23) AI and drone technology: Regulation and countermeasures (51:05) Crypto's economic value, personal freedoms, and investment risks (1:01:27) Entrepreneur wellness, Trump's EV policies, and state vs. federal regulation (1:04:23) New admin’s influence on M&A, antitrust laws, and startup ecosystems (1:09:08) Upcoming tech IPOs, tax policy, and regulatory capture discussion * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (10:17) PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. (19:58) OpenPhone. TWiST listeners can get 20% off your first 6 months at https://openphone.com/twist (30:23) LinkedIn Jobs. TWiST listeners can post their first job for free at https://www.linkedin.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1h 12m

  8. 17 JAN

    TikTok Ban, Data Centers in Space… and What's a Vector? | E2073

    Today’s show: Alex sits down with two CEOs from companies freshly added to the TWIST500. We get a masterclass from Bob van Luijt of Weaviate, on vector databases helping AI and LLMs do what they do. An then Philip Johnston from Lumen Orbit explains his vision of building data centers in space! * Timestamps: (0:00) Alex kicks off the show. (0:58) Supreme Court ruling on TikTok and key market numbers (3:49) Interview introduction with Weaviate and Lumen Orbit CEOs (4:06) Deep dive into vector databases with Weaviate's Bob van Luijt. (8:23) Lemon. TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (11:35) Exploring deep learning, vector indexing, and Weaviate's open-source significance (18:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist ⁠today. (19:32) Discussion on vector databases use cases and retrieval augmented generation (RAG) (27:17) Weaviate's business model, revenue streams, and growth (28:12) Vanta. TWiST listeners automate your SOC2 and get $1,000 off at http://www.vanta.com/twist (32:52) The future of AI, agentic architectures, and enterprise adoption (40:50) Lumen Orbit's vision for space-based data centers (42:54) Philip Johnston on the technical aspects of Lumen Orbit (49:12) Satellite demonstrators, technology challenges, and VC interest (53:26) Addressing chip obsolescence and cost advantages in space (56:21) Deployment strategies and competition in the space data center market (1:00:12) Strategies for staying ahead of competition and future plans for Lumen Orbit * Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Check out Weaviate: https://weaviate.io/ Check out Lumen Orbit: https://www.lumenorbit.com/ * Follow Bob: X: https://x.com/bobvanluijt LinkedIn: https://www.linkedin.com/in/bobvanluijt * Follow Philip: X: https://x.com/johnstonphil LinkedIn: https://www.linkedin.com/in/johnstonphilip/ * Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm * Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis * Thank you to our partners: (8:23) Lemon. TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (18:03) Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist (28:12) Vanta. TWiST listeners automate your SOC2 and get $1,000 off at http://www.vanta.com/twist * Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland * Check out Jason’s suite of newsletters: https://substack.com/@calacanis * Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com * Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

    1h 3m
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Hosts & Guests

About

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Information

  • Creator
    Jason Calacanis
  • Years Active
    2009 - 2025
  • Episodes
    1.2K
  • Rating
    Clean
  • Copyright
    © Jason Calacanis
  • Show Website
    This Week in Startups

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