STEIN Fireside Podcast

steinfiresidepodcast

The STEIN Fireside Podcast is a series hosted by the Society for Technology, Engineering, and Innovation in Neurosurgery (STEIN). Its purpose is to create an informal yet deeply insightful platform for discussing cutting-edge topics in neuroscience, neurosurgery, and related technologies. Episodes feature conversations with leading experts who share their research, clinical experiences, and perspectives on the future of brain science and interventions.

  1. 1 Apr

    Waves of the Mind: Dr. Michael Breakspear on Brain Dynamics, Surfing & Science

    In this episode of the STEIN Fireside Podcast, Dr. Kai Miller and Bryan Klassen sits down with world‑renowned neuroscientist, psychiatrist, mathematician — and lifelong surfer — Dr. Michael Breakspear. They dive into Breakspear’s unconventional path through math, medicine, physics, and psychiatry, and how those experiences shaped his groundbreaking work on neural field theory, brain oscillations, and large‑scale brain dynamics. From his early days programming on 1980s Mac computers to surfing the powerful reefs of Newcastle, Breakspear shares how curiosity, creativity, and lifestyle balance fuel his scientific thinking. You’ll hear discussion on: How dynamical systems and wave equations reveal hidden structure in brain activity Why large‑scale brain modes may explain attention, cognition, and consciousness How hippocampal traveling waves shape memory, behavior, and epilepsy What theory of mind, autism, and interoception might look like through a dynamical-systems lens The parallels between neuroscience and AI, including latent manifolds and generative modeling The importance of pure mathematics in modern science The role of physical embodiment, stress regulation, and human connection in psychiatry Whether you’re into neuroscience, physics, AI, medicine, or just love a good story about surfing and science colliding, this episode is a deep, engaging ride through the brain’s most beautiful patterns.

    54 min
  2. 15 Mar

    STEIN Fireside Podcast: Microelectrode Recording in DBS Surgery

    In this episode, Dr. Kai Miller (Neurosurgery) and Dr. Bryan Klassen (Neurology) from Mayo Clinic dive into the fundamentals of microelectrode recording (MER) and its role in deep brain stimulation (DBS) surgery. They break down: Why Microelectrode Recording Still Matters The ongoing debate of awake vs. asleep DBS Whether MER is “outdated” or still essential in the era of advanced imaging Their philosophy: MER is a critical adjunct, not a replacement for high‑resolution MRI How MER Works Using high‑impedance microelectrodes to detect single‑neuron activity Listening to real‑time firing patterns to confirm entry into specific brain structures Differentiating white matter vs. gray matter, nucleus boundaries, and disease‑related firing patterns Mapping the Brain During Surgery “Exploratory” vs. “confirmatory” MER approaches Using the Ben Gun device for multi‑trajectory mapping Understanding firing signatures of What Surgeons Listen For Voluntary movement‑related cell firing Passive movement sensory responses Tremor‑coherent neuronal firing Visual pathway confirmation using optic tract flashes Why This Matters for Patient Outcomes MER helps surgeons precisely place modern segmented DBS leads, which require millimeter‑level accuracy Ensures targeting of the most symptom‑relevant neural circuits Helps avoid complications by identifying sensitive regions (e.g., sensory thalamus, optic tract) The Human Element Importance of patient comfort and open interaction during awake DBS Real‑time teamwork between neurology, neurosurgery, and the OR staff

    23 min

About

The STEIN Fireside Podcast is a series hosted by the Society for Technology, Engineering, and Innovation in Neurosurgery (STEIN). Its purpose is to create an informal yet deeply insightful platform for discussing cutting-edge topics in neuroscience, neurosurgery, and related technologies. Episodes feature conversations with leading experts who share their research, clinical experiences, and perspectives on the future of brain science and interventions.

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