RhAPPcast

Rheumatology Advanced Practice Providers (RhAPP)

This is the official podcast of Rheumatology Advanced Practice Providers (RhAPP), a non-profit 501c3 organization dedicated to developing educational programs, providing professional advancement services, and assembling resources for—and guided by—advanced practice providers (APPs).    Through our peer-to-peer network, we seek to support the integral role APPs play in the rheumatology healthcare community by providing the most relevant and timely information and communication for the treatment of their patients with rheumatic diseases. 

  1. 8月27日

    FAQ: What Are Key Diagnostic Considerations and Limitations of Antibody Testing in IIM?

    In this FAQ video module, Jennifer Mylod, nurse practitioner with Arizona Arthritis Rheumatology Associates in Phoenix, Arizona, discusses key diagnostic considerations and limitations of antibody testing in idiopathic inflammatory myopathies, including myositis, dermatomyositis, and other inflammatory muscle diseases. While myositis antibody panels can provide valuable information for diagnosis, prognosis, and disease classification, antibody testing has important limitations that clinicians must recognize. A negative myositis panel does not rule out inflammatory myopathy, as some patients may be seronegative, and false-positive results or variability between commercial laboratory assays can complicate interpretation. This educational review emphasizes that antibody results should never be interpreted in isolation, but instead should be evaluated alongside the patient’s clinical presentation, CK levels, MRI findings, EMG results, and muscle or skin biopsy findings. Jennifer also highlights that not all antibody panels include every known myositis-specific or myositis-associated antibody, making clinical judgment essential when evaluating suspected idiopathic inflammatory myopathy. Designed for rheumatology advanced practice providers, nurse practitioners, physician assistants, and clinicians caring for patients with autoimmune muscle disease, this FAQ provides practical guidance for improving diagnostic accuracy and understanding the role of antibody testing in myositis care. For more rheumatology education and clinical resources, visit RhAPP’s website, the RhAPP content rheum, or the RhAPP ACE app.

  2. 8月18日

    Journal Club Review: Deucravacitinib in Active PsA: 52-Week Efficacy and Safety From POETYK PsA-2

    In this RhAPP journal club video module, Danielle Gatti Palumbo, PharmD, reviews the Phase 3 POETYK PsA-2 clinical trial evaluating deucravacitinib in adults with active psoriatic arthritis. Deucravacitinib is an oral, selective tyrosine kinase 2, or TYK2, inhibitor that targets signaling pathways involved in psoriatic arthritis, including interleukin-23 and type I interferons. This randomized, double-blind, placebo-controlled study assessed the efficacy and safety of deucravacitinib through 52 weeks in patients who were biologic-naive or had previously received conventional disease-modifying antirheumatic drugs or TNF inhibitors. This episode reviews the POETYK PsA-2 trial design, patient population, primary and secondary endpoints, and key clinical findings. It examines improvements in ACR20, ACR50, and ACR70 responses, as well as skin symptoms, physical function, minimal disease activity, dactylitis, and enthesitis. Danielle also discusses the sustained response observed through week 52, outcomes among patients who crossed over from placebo to deucravacitinib, and the treatment’s safety profile, including common adverse events and findings related to serious infections, malignancy, major cardiovascular events, and venous thromboembolism. Designed for rheumatology advanced practice providers, pharmacists, nurse practitioners, physician assistants, and other clinicians caring for patients with psoriatic arthritis, this journal club highlights the potential role of selective TYK2 inhibition as an oral treatment option across multiple psoriatic arthritis disease domains. For more rheumatology education and clinical resources, visit RhAPP's website, the RhAPP content rheum, or the RhAPP ACE app.

  3. 8月13日

    RhAPPcast: Cracking the Code: A Rheum Derm Neuro Multispecialty Case Approach to Myositis

    In this episode of RhAPPcast, the official podcast of Rheumatology Advanced Practice Providers, host Amanda Mixon leads a multidisciplinary, case-based discussion titled “Cracking the Code: A Rheum-Derm-Neuro Multispecialty Case Approach to Myositis.” Joined by dermatology clinician Laura Bush and neuromuscular medicine PA Maggie Naclerio, this episode explores the complex and often subtle presentations of myositis, idiopathic inflammatory myopathies, dermatomyositis, immune-mediated necrotizing myopathy, and inclusion body myositis. Through real-world clinical cases, the conversation highlights how patients may first present with skin findings, proximal muscle weakness, falls, elevated CK levels, hoarseness, interstitial lung disease concerns, or atypical symptoms that can delay diagnosis. Listeners will gain practical insight into recognizing key myositis signs such as Gottron’s papules, heliotrope rash, shawl sign, holster sign, nailfold capillary changes, limb-girdle weakness, and functional decline, while also learning how dermatology, rheumatology, neurology, primary care, and pulmonology can collaborate to improve outcomes. The episode also covers important diagnostic tools and clinical pearls, including myositis antibody panels, CK trending, aldolase, ESR, CRP, thyroid testing, EMG, MRI, muscle biopsy, HMGCR antibodies, MDA5-associated disease, malignancy risk, false-positive antibody testing, and the importance of a high-quality physical exam. Designed for rheumatology APPs, physician assistants, nurse practitioners, dermatology clinicians, neurology providers, and all healthcare professionals caring for patients with autoimmune muscle disease, this episode emphasizes earlier recognition, better specialty coordination, and individualized treatment strategies for patients living with myositis. Subscribe to RhAPPcast for more rheumatology education, clinical insights, and practical updates from the RhAPP community.

簡介

This is the official podcast of Rheumatology Advanced Practice Providers (RhAPP), a non-profit 501c3 organization dedicated to developing educational programs, providing professional advancement services, and assembling resources for—and guided by—advanced practice providers (APPs).    Through our peer-to-peer network, we seek to support the integral role APPs play in the rheumatology healthcare community by providing the most relevant and timely information and communication for the treatment of their patients with rheumatic diseases. 

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