Translational Health Sciences

Oxford University

Turning innovations into practical solutions for healthcare needs is an imperative – and one that can only become more urgent as demands on health systems increase. Our key focus in this series is the ‘downstream’ phases of translational health sciences – the human, organisational and societal issues that impact on the adoption, dissemination and mainstreaming of research discoveries. Talks are taken from the Oxford Translational Health Sciences Programme and delivered by leaders in the field of Translational Health Care. CB

  1. 1d ago ·  Video

    Artificial Intelligence and the Ethics and Practice of Evaluation

    This talk argues for engaging with AI ethics before AI-led reasoning becomes institutionally embedded. Artificial intelligence (AI) presents both profound opportunities and unprecedented challenges for the evaluation profession. These remain insufficiently examined. Evaluators embrace AI for data analysis, evidence synthesis, and decision support. This talk examines three critical consequences: the reconfiguration of agency and responsibility; the epistemic risks of relinquishing human interpretive authority; and the impacts of Global North dominance in AI development. It argues for engaging with AI ethics before AI-led reasoning becomes institutionally embedded. It suggests that evaluative practice risks evolving from reflective human inquiry into procedural algorithmic compliance, altering evidence-based decision-making, learning, and accountability. About the speaker: Tom Ling has over 30 years of experience in designing, managing, and delivering complex evaluations focused on innovation, impact and quality. Most often these have focused on impact and outcome evaluations, and process and implementation evaluations. He has published widely on these and related evaluation challenges with a particular interest in strengthening the utilisation of evaluations. His clients have included UK Government Departments and agencies (including on the remuneration of and its motivation of UK military personnel), the European Commission, UNDP, OECD, the World Bank, and many others. He is a senior research leader at RAND Europe. In addition to his current role at RAND Europe, Tom was head of evaluation at Save the Children, a senior research fellow and the National Audit Office and held various academic posts. He is Professor Emeritus at Anglia Ruskin University. He is a recent-past President of the European Evaluation Society and now acts as a senior advisor to the Board. He was until December 2024 an advisor to the Global Evaluation Initiative, and he is a leading member of INTEVAL the International Evaluation Research Group. He led the analytical support for UNICEF’s 2025 review of their evaluation policy.

    1h 9m
  2. May 27 ·  Video

    Welcome to the New Era of Digital Health: Power, Politics and the Fight for Justice in the Age of AI

    This talk explores the complexities, entanglements and crossroads at which digital health as a field now lives and stands. Innovative digital technologies, such as AI, hold significant promise to further the global attainment of health and well-being. Such technologies could provide access to professional and personalized care at speed, scale and low-cost. However, in this field, the values, interests and ultimate goals of regulators, scientists, tech providers, and civic society (including patients) often clash and collide. The imaginaries, market-led promises and narratives that are circulated seem compelling: better public health, transformative innovation, and the seamless integration of digital tools and technologies with healthcare systems, practices and people. Yet, the realities that we end up with are often very different: public-private partnerships that are choreographed in favour of Big Tech and their exploitative business models; the implementation of powerful, yet untested and unstable AI models into real-life applications; and mounting justice issues that are rippling across society, whereby the most vulnerable are disproportionately affected by digital technologies, data and AI. This guest lecture explores the complexities, entanglements and crossroads at which digital health as a field now lives and stands. It also asks the question - and hopefully also provides some answers - of how we can address the issue of asymmetric power and market politics, and how we can take up the fight for justice to preserve not just the very essence of healthcare but also unlock the power of digital technologies for the greater good. About the speaker: Nicole Gross is an Associate Professor in Business & Society at the National College of Ireland. Her research interests sit in between organization studies, digital tech markets and the ‘greater good’ in the context of healthcare. She is particularly interested how business models and markets work, if/how market trajectories can be changed and what needs to be done to deliver public value in digital healthcare. Nicole is an active member of various research groups (e.g., https://misfires.ucd.ie/) and collaborates with Irish as well as European advocacy groups on issues related to AI and health (e.g., https://healthai.haiweb.org/the-members/). Nicole has been awarded funding from Research Ireland for her recent work on generative AI in healthcare and her research has been widely published in outlets such as Organization Studies, Big Data & Society, Business & Society, Organization, Sociology of Health & Illness, AI &Ethics, Journal of Medical Ethics, BMJ, Health Policy & Technology, and Marketing Theory. Nicole tweets under @tech_spaces.

    1h 2m
  3. May 21 ·  Video

    Evidence to Action: Science Communication in Global Health

    Fireside conversation between Prof Devi Sridhar and Mia Malan exploring how scientific evidence is translated into public understanding and collective action in global health. Drawing on Prof Devi Sridhar’s experience as a prominent public voice in print, broadcast, and digital media, and Mia Malan's expertise as editor-in chief of Bhekisisa Centre for Health Journalism, it examines how experts communicate risk, uncertainty, and urgency across rapidly changing public health contexts. The fireside conversation will consider both the opportunities and challenges of science communication, asking how global health expertise can inform public debate while maintaining trust, clarity, and scientific integrity. About the speakers: Devi Sridhar is a writer, broadcaster and world-leading expert in public health and wellbeing. She is Professor and Chair of Global Public Health at the University of Edinburgh and has advised the WHO, UNICEF, UNESCO and the Scottish, UK and German governments. Devi appears regularly on ITV and Channel 4 News, has a weekly column in the Guardian, tweets to over 300,000 followers, and recently became a certified Level 3 Personal Trainer. Her first book, Preventable, was a BBC Radio 4 Book of the Week and a Sunday Times bestseller. She has also authored the newly released How Not to Die (Too Soon)' Mia Malan is the founder and editor-in-chief of the Bhekisisa Centre for Health Journalism in South Africa. She has worked in newsrooms in Johannesburg, Nairobi and Washington, DC and is a 2025/6 senior fellow in global health communication leadership at the University of Southern California.

    44 min
  4. Mar 25 ·  Video

    Beyond Barriers and Enablers: Mechanisms as the Missing Middle in Implementation Science

    Prof Carolyn Steele-Gray discusses the critical gap in understanding of underlying mechanisms that are activated by strategies to generate desired implementation outcomes. Despite substantial growth in implementation research, the field has become increasingly dominated by frameworks and studies that catalogue barriers and enablers to implementation success. While these approaches have been instrumental in identifying contextual determinants of uptake, they often stop short of explaining how implementation strategies produce change. As a result, implementation studies frequently emphasize what strategies were used to support putting an innovation into practice, and whether those strategies achieved intended outcomes, while paying far less attention to the cognitive, relational, organizational, and team-level processes through which change unfolds. This imbalance has left a noted critical gap in our understanding of the underlying mechanisms that are activated by strategies to generate desired implementation outcomes. In this lecture, Dr. Carolyn Steele Gray draws on insights from cognitive psychology (e.g., habit formation and mental models), sociology (e.g., professional identity, power, and social networks), organizational and team science (e.g., leadership, sense- making, and team processes), and theories of innovation and adoption (e.g., diffusion of innovations) that can help reveal the mechanisms that can underlie strategy success. Using empirical examples from studies of digital health and integrated care implementation, the lecture illustrates how a developed understanding mechanisms can help better tailor strategies to unique environments, helping to shape adaptation, spread, and sustainability of innovations in complex health systems. The session also explores the methodological challenges associated with studying mechanisms, including issues surrounding definitional clarity, complexity, temporality, and multi-disciplinary dynamics that may not be adequately captured by dominant evaluation approaches. By foregrounding mechanisms as a critical but understudied force in implementation, this lecture argues for a more theory-driven and mechanism-informed approach to strategy development which can help to enable scale, transferability, and long-term sustainability of innovation. About the speaker: Carolyn Steele Gray, MA, PhD holds a Tier 2 Canada Research Chair in Implementing Digital Health Innovation. She is a Senior Investigator at the Science of Care Institute and in the Lunenfeld-Tanenbaum Research Institute at Sinai Health, and an Associate Professor in the Institute for Health Policy, Management and Evaluation at the University of Toronto in Canada. Dr. Steele Gray is an Implementation Scientist whose program of work focuses on the role of digital health in supporting integrated, person-centred and primary care delivery for patients with complex care needs, applying implementation science theory and approaches, along with evaluation methods to uncover to how best to embed technology into novel delivery models. Key to her transformational work is her international leadership in the areas of digital health and integrated care, notably through her work as a Senior Associate with the International Foundation for Integrated Care (IFIC), and a member of the Executive committee with IFIC Canada, where she co-leads a Special Interest Group in Digital Services and Data Enabling Integrated Care, providing strategic guidance and expertise through IFIC programs like their international Integrated Care Academy. Her national and international leadership in the fields of digital health implementation and integrated primary care was recognized by Digital Health Canada who awarded her Digital Health Leader of the Year in 2025 as well as by the North American Primary Care Research Group who awarded her the Mid-Career Scientist Award in 2025.

    1h 7m
  5. Mar 12 ·  Video

    Why Sustainability in Health Care Cannot Be Implemented: From Implementation Failure to Ongoing Mediation

    Prof Eivind Engebretsen discusses why sustainability in health care cannot be implemented. Sustainability in health care is widely framed as a problem of implementation: policies are designed, evidence is assembled, and failure is diagnosed when action does not follow. This lecture challenges that framing. Prof Engebretsen argues that sustainability in health care cannot be implemented because it is not a stable programme but a contested, value-laden practice that takes shape through mediation rather than delivery. Treating sustainability in health care as implementable is therefore a category error—one that helps produce the very problem it seeks to resolve, by recoding alternative values as barriers and situated practices as deficits requiring correction.   Drawing on a recent systematic review of grassroots indicators across fields and sectors—including sustainability indicators— Prof Engebretsen shows that in these projects sustainability was not absent, waiting to be implemented, but already being practised—through livelihoods, norms of resource use, and shared understandings of what could and could not be sustained. What was missing was not action, but a language in which such practices could count as sustainability within policy frameworks. What is commonly described as an “implementation gap” is therefore better understood as a space of ongoing mediation, where knowledge, values, and authority are continually renegotiated. Sustainability in health care, on this view, is always already happening—not as logistical rollout, but in grassroots initiatives, everyday practices of care, and irresolvable disagreements over what should be sustained, for whom, and at what cost. The task is not to implement sustainable health care more efficiently, but to recognise, engage with, take responsibility for, and strengthen the forms of sustainability already in motion by rendering them visible and politically intelligible.   About the speaker: Professor Eivind Engebretsen is a medical humanities scholar and professor of interdisciplinary health science at the University of Oslo, serving since 2023 as Dean of the Open Campus at the European University Alliance Circle U, and founding head of the Sustainable Health Unit (SUSTAINIT) and the Centre for Sustainable Healthcare Education (SHE), a Norwegian government- funded Centre of Excellence in Education. His research explores how medical knowledge is generated, applied, documented, evaluated, and communicated in clinical encounters as well as in broader societal contexts.

    1h 1m
  6. Jan 23 ·  Video

    Economics of Global Biopharmaceutical Market Design: Value, Health Technology Assessment, and Access

    Professor Lou Garrison gives a whistle-stop tour de force of his many years of work at the interface of innovation markets and innovation value to healthcare systems and patients. Professor Lou Garrison gives a whistle-stop tour de force of his many years of work at the interface of innovation markets and innovation value to healthcare systems and patients. He delves into his international work on evolving value frameworks in rethinking how we capture and assess the value of innovation, beyond the economic value via concepts of productivity, spillover and equity value. He casts a critical eye over cost effectiveness analysis and access against the rapidly changing political backdrop of governments grappling with health care cost containment. About the speaker: Lou Garrison, PhD, is Professor Emeritus in The Comparative Health Outcomes, Policy, and Economics Institute in the School of Pharmacy at the University of Washington, where he joined the faculty in 2004. He is also a Visiting Senior Fellow at the Office of Health Economics in London following his sabbatical there in 2012-13. Professor Garrison received a PhD in Economics from Stanford University and has more than 200 publications in peer-reviewed journals. For the first 13 years of his career, he worked in non-profit health policy. Following this, he worked as an economist in the pharmaceutical industry for 12 years. His research interests include national and international health policy issues related to health technology assessment, personalized medicine, benefit-risk analysis, and other topics, as well as the economic evaluation and pricing of biopharmaceuticals, diagnostics, and other technologies. Professor Garrison was elected as ISPOR President for July 2016-June 2017. He has served as co-chair of ISPOR’s Policy Outlook Committee for Health Science Policy Council, and he is currently a leader of the ISPOR Special Interest Group on Global Access to Medical Innovation.  In September 2022, he received the Avedis Donabedian Outcomes Research Lifetime Achievement Award from ISPOR.

    1h 2m
  7. 12/11/2025 ·  Video

    Storytelling, a powerful tool, but does it help lead to behaviour change?

    Dr Becky McCall examines the potential of digital storytelling as part of the behavioural science framework. Within public health, storytelling - including digital storytelling (DST) - is frequently examined through a scientific lens, whether as a research method or an interventional tool for influencing behaviour change. However, DST is inherently an arts-based practice, grounded in the creation of authentic, 3–5-minute videos that convey personal experiences of illness. Its strength lies in the interpretation and emotional meaning generated through the storytelling process, both for the storyteller creators and for audiences. In my recent work, I examine the potential of DST to relate experiences of antibiotic resistance and antibiotic adversity to the lay public. Using qualitative data from a public screening and discussion of five digital stories, we explore the extent to which this arts-based, largely emotion-driven method can be situated within a behavioural science framework, and whether it may form part of a causal pathway towards reducing unnecessary antibiotic use among the general public. About the speaker: Dr Becky McCall has been a medical journalist working for various global news outlets for 20 years. Most of her work has been in the written format, but she has also worked in radio and television. She has watched with interest as the patient voice has shifted from the margins to adopting an increasingly central role in medical discourse. Her recent PhD work challenged assumptions around public perceptions of antimicrobial resistance (AMR) through the creation of digital stories as an interventional tool to shape mindsets around the use of antibiotics. She has just been awarded a PhD from University College London. Some of her stories can be found at StoryBug. Please note, the sound of the story Dr McCall showed in this talk was not recorded but you can find this story and others at her website https://storybug.org.uk/.

    53 min
  8. 05/13/2025 ·  Video

    Politics and Global Health: The Need for a New, Resilient Architecture

    Mitchell Warren will provide updates on AIDS Vaccine Advocacy Coalition's (AVAC) court challenge against the Trump administration’s dismantling of USAID and offer his insights into what a more resilient global health funding infrastructure could look like Recent, dramatic shifts in global health funding include cuts to US and UK foreign aid. This has had a cascade of devasting consequences on treatment and prevention programmes, including for HIV and TB across the globe. Mitchell Warren will provide updates on AIDS Vaccine Advocacy Coalition's (AVAC) court challenge against the Trump administration’s dismantling of USAID and offer his insights into what a more resilient global health funding infrastructure could look like. About the speaker: Mitchell Warren has spent nearly 30 years devoted to expanding access to HIV prevention, working with a wide range of activists and advocates, researchers and scientists, product developers and deliverers, policy makers, community advisory boards and the media from across the globe. This has often been as a translator, helping these often-diverse groups with diverse points of view understand each other better. Since 2004, Mitchell has been the Executive Director of AVAC, an international non-governmental organization that works to accelerate the ethical development and global delivery of HIV prevention options as part of a comprehensive and integrated pathway to global health equity. Through communications, education, policy analysis, advocacy and a network of global collaborations, it mobilizes and supports efforts to deliver proven HIV prevention tools for immediate impact, demonstrates and rolls out new HIV prevention options, and develops long-term solutions needed to end the epidemic.

    42 min

About

Turning innovations into practical solutions for healthcare needs is an imperative – and one that can only become more urgent as demands on health systems increase. Our key focus in this series is the ‘downstream’ phases of translational health sciences – the human, organisational and societal issues that impact on the adoption, dissemination and mainstreaming of research discoveries. Talks are taken from the Oxford Translational Health Sciences Programme and delivered by leaders in the field of Translational Health Care. CB