10 episodes

AudioHelicase, the podcast of Whitehead Institute: Unwinding the science and the people behind some of the Institute’s most exciting discoveries.



Whitehead Institute is a world-renowned non-profit research institution dedicated to improving human health through basic biomedical research. By cultivating a deeply collaborative culture and enabling the pursuit of bold, creative inquiry, Whitehead fosters paradigm-shifting scientific achievement. For more than 30 years, Whitehead faculty have delivered breakthroughs that have transformed our understanding of biology and accelerated development of therapies for such diseases as Alzheimer’s, Parkinson’s, diabetes, and certain cancers.

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    • Science
    • 5.0 • 2 Ratings

AudioHelicase, the podcast of Whitehead Institute: Unwinding the science and the people behind some of the Institute’s most exciting discoveries.



Whitehead Institute is a world-renowned non-profit research institution dedicated to improving human health through basic biomedical research. By cultivating a deeply collaborative culture and enabling the pursuit of bold, creative inquiry, Whitehead fosters paradigm-shifting scientific achievement. For more than 30 years, Whitehead faculty have delivered breakthroughs that have transformed our understanding of biology and accelerated development of therapies for such diseases as Alzheimer’s, Parkinson’s, diabetes, and certain cancers.

    AudioHelicase Special: RNA in health and disease

    AudioHelicase Special: RNA in health and disease

    Whitehead Institute researchers Silvi Rouskin, Ankur Jain, and David Bartel discuss how their RNA research connects to health and disease, including viral infections and neurodegeneration. This podcast is part of a multimedia series on RNA.

    • 17 min
    AudioHelicase Special: Rebuilding a Body

    AudioHelicase Special: Rebuilding a Body

    In this special episode of AudioHelicase, we talk to three researchers about the cells in our bodies that can regenerate – and those that can’t. We ask, why can some cells no longer renew themselves? And, importantly, can we change that? This podcast is part of our multimedia series, Cells Over Time.

    • 15 min
    AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future

    AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future

    Making our world more sustainable to preserve it for future generations will take not just one but many solutions. Researchers at Whitehead Institute are exploring how the natural world could teach us how to improve the sustainability of how we produce food, how we make medicines, how we make products more durable, and potentially how … Continue reading AudioHelicase Special: How researchers at Whitehead Institute are building a more sustainable future →

    • 18 min
    Whitehead Institute’s Silvi Rouskin on solving the structure of the coronavirus genome

    Whitehead Institute’s Silvi Rouskin on solving the structure of the coronavirus genome

    In this episode of AudioHelicase Podcast, Whitehead Fellow Silvi Rouskin discusses her research on solving the structure of the novel coronavirus’s RNA genome, with the goal of revealing weak points in the virus’s gene regulation that new drugs could potentially target. Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.

    • 17 min
    Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics

    Whitehead Institute’s Olivia Corradin on a New Way to Probe Disease Genetics

    On this episode of AudioHelicase podcast, Whitehead Fellow Olivia Corradin talked about investigating the genetic underpinnings of diseases through a new technique she developed, the outside variant approach. Applying the method to study the autoimmune disease multiple sclerosis (MS), Corradin and colleagues identified a role for a cell type in the brain in MS, offering a new way of understanding the disease. She also discussed running a lab during the COVID-19 pandemic, and evaluating scientific information in a time of uncertainty.



    Music: “Versailles” by Pierce Murphy (CC-BY 4.0). Produced by Conor Gearin.

    • 25 min
    Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science

    Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science

    Plants have been used as medicine for thousands of years; could they contribute to a solution to the COVID-19 pandemic? This is what Whitehead Institute Member Jing-Ke-Weng set out to address in a new paper, published May 20 in the journal Molecular Plant. We talked to Weng about an herbal treatment being used to treat … Continue reading Whitehead’s Jing-Ke Weng on COVID-19 treatments taking root in plant science →

    • 7 min

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