AudioScholar Neurology Weekly

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Neurology — a weekly podcast briefing of the most significant peer-reviewed neurology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 3d ago

    This Week in Neurology — Aug 26, 2026

    Welcome to This Week in Neurology. This week we're covering 10 notable papers spanning cerebrovascular disease and haemorrhage management, antibody-mediated central nervous system disease, and the biology and prognostication of neurodegeneration, wit… This week's papers: 1. Evidence Update for Minimally Invasive Surgical Evacuation of Supratentorial Spontaneous Intracerebral Hemorrhage: A Science Advisory From the American Heart A… — Stroke 2026 2. De-Escalating and Discontinuing Immunotherapies in Patients With NMOSD and MOGAD — Neurology 2026 3. Safety, tolerability, and efficacy of alixorexton, a selective orexin 2 receptor agonist for narcolepsy type 1 (Vibrance-1): a randomised, double-blind, placeb… — The Lancet Neurology 2026 4. TDP-43-Associated Neurodegenerative Disease Conceptualization and Integrated Staging: A Review — JAMA Neurology 2026 5. Body Weight in Relation to the Effectiveness of Intravenous Alteplase in Acute Ischemic Stroke: The ENCHANTED Trial — Stroke 2026 6. Postural Orthostatic Tachycardia Syndrome (POTS): A Review — JAMA 2026 7. Lifelong De Novo Aneurysm Risk After Aneurysmal Subarachnoid Hemorrhage in Young Survivors — JAMA Neurology 2026 8. EOAD-Signature Atrophy Predicts Dementia in Early-Onset MCI due to Alzheimer Disease: An MRI-Based Prognostic Biomarker — Neurology 2026 9. Prevalence of chronic traumatic encephalopathy at death in National Football League players: retrospective population based cohort study, 2008-21 — BMJ 2026 10. Antibodies against MLC1 found in patients with NMOSD-like disease mediate astrocytopathy in rodent models — Science Translational Medicine 2026 Listen at https://audioscholar.cc/episode/bjd9wn7wcr

  2. Aug 20

    This Week in Neurology — Aug 19, 2026

    Welcome to This Week in Neurology. This week we're covering 10 notable papers spanning multiple sclerosis diagnosis and disease-modifying therapy safety, epilepsy pharmacology and access to surgery, and a set of antibody-driven diagnoses that are eas… This week's papers: 1. Application of the 2024 McDonald Criteria: Earlier Diagnosis and Avoiding Misdiagnosis of Multiple Sclerosis in a Global Setting — Neurology 2026 2. Safety of Antiseizure Medications During Direct Oral Anticoagulant Therapy in Epilepsy — JAMA Neurology 2026 3. Anti-CD320 Autoantibodies and Central Nervous System Vitamin B12 Deficiency in Idiopathic Myelopathy — JAMA Neurology 2026 4. Perils and progress in epilepsy surgery utilization: Twenty-five years later — Epilepsia 2026 5. Early sodium channel blocker initiation is associated with better outcomes in KCNQ2 disorders — Brain 2026 6. Paternal Valproate Exposure and Offspring Neurodevelopmental Outcomes — Neurology 2026 7. Time-dependent divergence in infection risks among patients with multiple sclerosis treated with fumarates versus anti-CD20 monoclonal antibodies — Multiple Sclerosis Journal 2026 8. Outcomes of out-of-hospital treatment of impending tonic-clonic status epilepticus with diazepam nasal spray — Epilepsia 2026 9. Fatal cerebral toxoplasmosis in a patient with multiple sclerosis treated with natalizumab — Multiple Sclerosis Journal 2026 10. Sick sinus syndrome: A harbinger of anti-LGI1 encephalitis — Epilepsia 2026 Listen at https://audioscholar.cc/episode/hxm4ukv3ev

  3. Aug 13

    This Week in Neurology — Aug 12, 2026

    Welcome to This Week in Neurology. This week we're covering 10 notable papers spanning blood pressure and vascular intervention in stroke, drug safety decisions in pregnancy and in dementia, risk stratification in early cognitive decline, and diagnos… This week's papers: 1. Individualized vs Standard Blood Pressure Control During Thrombectomy for Ischemic Stroke: The DETERMINE Randomized Clinical Trial — Neurology 2026 2. Antiseizure medication use in pregnancy and the risk of poor fetal growth in the EURAP international registry: a prospective cohort study — The Lancet Neurology 2026 3. Intensive blood pressure lowering after spontaneous intracerebral haemorrhage for secondary stroke prevention (RECAP-ICH): a systematic review and individual p… — The Lancet Neurology 2026 4. Accuracy of Antibody Testing in Myasthenia Gravis: The ADAM Study — Neurology 2026 5. Cholinesterase inhibitors in people with dementia with Lewy bodies and cardiac conduction abnormalities — The Lancet Neurology 2026 6. Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment — Annals of Neurology 2026 7. Association Between Menopausal Hormone Therapy and Alzheimer Disease Neuropathology — Neurology 2026 8. Intervention or Conservative Management for Symptomatic Cerebral Cavernous Malformations: A Prospective, Population-Based Cohort Study — Neurology 2026 9. Safety and efficacy of guanabenz in early-childhood onset vanishing white matter: primary analysis of a single-arm, phase 1/2 trial — The Lancet Neurology 2026 10. Comparison of Brain Age With Standard MRI Assessment for Dementia Risk Stratification in Subjective and Mild Cognitive Impairment — Neurology 2026 Listen at https://audioscholar.cc/episode/tnkgz2pt3u

  4. Aug 8

    This Week in Neurology — Aug 7, 2026

    Welcome to This Week in Neurology. This week we're covering 10 notable papers spanning acute stroke and cerebrovascular care, pediatric neuroimmunology, and the increasingly biomarker-driven world of neurodegenerative and neuromuscular disease. Let's… This week's papers: 1. Outcomes of Intra-Arterial Tenecteplase after Endovascular Reperfusion for Acute Ischemic Stroke Due to Cardioembolism and Non-Cardioembolism: A Secondary Anal… — Annals of Neurology 2026 2. Acute Attack Treatment Escalation and Subsequent Relapse Risk in Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease — Neurology 2026 3. Cannabis-Based Oil for Pain and Other Non-Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial — Movement Disorders 2026 4. Defining the underlying pathology of corticobasal syndrome using clinical features and biomarkers — Brain 2026 5. Rate of Autoimmune Diseases in the 10 Years Preceding Myasthenia Gravis Diagnosis: A Nationwide Cohort Study in South Korea — Neurology 2026 6. Nongenetic Factors Associated With Onset and Severity of Hereditary Ataxia — Neurology 2026 7. Associations Between Cerebral Amyloid Angiopathy, Cognitive Impairment, and Depressive Symptoms — Neurology 2026 8. Quantifying Disease Progression in Patients With Charcot-Marie-Tooth Neuropathy Type 1A Using Quantitative Muscle MRI and Clinical Outcomes — Neurology 2026 9. Machine Learning Characterization of Readmissions After Chronic Subdural Hematoma Hospitalizations — Neurology 2026 10. Frequent early cognitive impairment in both pediatric MS and MOGAD — Multiple Sclerosis Journal 2026 Listen at https://audioscholar.cc/episode/9qxfcrxuve

  5. Aug 1

    This Week in Neurology — Jul 31, 2026

    Welcome to This Week in Neurology. This week we're covering 7 notable papers spanning diagnostic stratification in cognitive and seizure disorders, therapeutic and physiological insights in movement disorders and neuroimmunology, and systemic optimiz… This week's papers: 1. Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single-Arm Clinical Trial. — Annals of Neurology 2026 2. Validation of the VasCog-2-WSO VCID Criteria in a Dementia-Free and Stroke-Free Community Cohort: Cardiovascular Risk and Mortality. — Neurology 2026 3. Distal Electroacupuncture Modulates Maladaptive Brainstem and Motor Cortex Plasticity to Alleviate Hemifacial Spasm. — Movement Disorders 2026 4. Optimizing Acute Ischemic Stroke Systems of Care: Current State and Future Directions. — Stroke 2026 5. Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis. — Annals of Neurology 2026 6. Does age influence diagnostic outcomes in an adult cohort referred to a first-seizure clinic? — Epilepsia 2026 7. Movement dependent neural substates within levodopa-induced dyskinesia in Parkinson's disease. — Brain 2026 Listen at https://audioscholar.cc/episode/vj737ea96u

  6. Jul 25

    This Week in Neurology — Jul 24, 2026

    Welcome to This Week in Neurology. This week we're covering 7 notable papers spanning stroke and neurovascular care, multiple sclerosis, headache medicine, and movement disorders. Let's dive in. Beginning with vascular neurology and acute stroke car… This week's papers: 1. Tolerability, safety, and efficacy of atogepant versus topiramate in adults with migraine (TEMPLE): a randomised, head-to-head, phase 3b trial. — The Lancet. Neurology 2026 2. Treatment escalation after clinically silent MRI lesions in relapsing-remitting multiple sclerosis. — Brain : a journal of neurology 2026 3. Age Is an Effect Modifier of Thrombectomy Benefit in a Socioeconomically Vulnerable Stroke Population. — Annals of Neurology 2026 4. Bilateral gamma knife radiosurgery in severe essential tremor: a prospective trial. — Brain : a journal of neurology 2026 5. IV Thrombolysis in the Extended Time Window for Acute Ischemic Stroke: An Updated Systematic Review and Meta-Analysis. — Neurology 2026 6. Delayed Recognition and Stroke-Predominant Presentation in Down Syndrome-Associated Moyamoya Syndrome. — Stroke 2026 7. Acute Kidney Injury After Intensive Blood Pressure Lowering Following Successful Endovascular Thrombectomy. — Stroke 2026 Listen at https://audioscholar.cc/episode/7jsscbr4j9

  7. Jul 18

    This Week in Neurology — Jul 17, 2026

    Welcome to This Week in Neurology. This week we are covering ten notable papers spanning acute stroke interventions, the complex genetic and pathological landscapes of neurodegenerative diseases, and practical clinical safety and measurement tools in… This week's papers: 1. Comparison of the Efficacy and Safety of Myasthenia Gravis Treatments: A Bayesian Network Meta-Analysis — Neurology 2026 2. General Anesthesia Versus Non-GA in Endovascular Therapy for Acute Ischemic Stroke: A Systematic Review and Bayesian Meta-Analysis of RCTs — Neurology 2026 3. Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis After Initiation of Antiseizure Medication: A Danish Nationwide Cohort Study — Neurology 2026 4. Immunotherapy with a short-lived anti-PD-L1 antibody in Alzheimer's disease: a phase 1b, randomized, double-blind trial — Nature medicine 2026 5. Ischemic Postconditioning in Patients With Acute Stroke With Successful Recanalization After Endovascular Therapy: A Pilot Randomized Controlled Trial — Stroke 2026 6. Parkinson's disease genetics across diverse ancestries: an observational genetic study of causal and risk variants with translational implications — The Lancet. Neurology 2026 7. Brain-first and body-first subtypes of Lewy body disease — Nature reviews. Neurology 2026 8. Deep brain stimulation for the treatment of patients with dystonia: advances towards network-based personalised care — The Lancet. Neurology 2026 9. Rasch-Built Overall Disability Scale for Chronic Idiopathic Axonal Polyneuropathy — Neurology 2026 10. Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression — Annals of neurology 2026 Listen at https://audioscholar.cc/episode/fqrttnm7fg

  8. Jul 9

    This Week in Neurology — Jul 8, 2026

    Welcome to This Week in Neurology. This week we are covering ten notable papers spanning three broad themes: optimizing acute stroke care and preventive risk assessment, advancing diagnostic precision and pathophysiological insights in neuromuscular… This week's papers: 1. MAD-MT Score: A Tool to Optimize Patient Selection for Mechanical Thrombectomy in Distal Vessel Occlusions — Stroke 2026 2. Phenotype, Severity, and Therapy of Patients With LRP4 Antibody-Associated Myasthenia Gravis in the German Myasthenia Gravis Registry — Neurology 2026 3. A new Patient-Reported Outcome Scale to assess autoimmune Encephalitis: PROSE — Annals of Neurology 2026 4. Role of the Upper Motor Neuron in the Generation of Fasciculations in Early Disease Stages of Amyotrophic Lateral Sclerosis — Neurology 2026 5. Neurophysiological Recovery Following Nerve Transfer Surgery to Restore Upper Limb Function after Cervical Spinal Cord Injury — Annals of Neurology 2026 6. Epileptogenic lesions in the Australian epilepsy project: A harmonized 3-T magnetic resonance imaging protocol and its diagnostic yield — Epilepsia 2026 7. Post-stroke acute heart failure in patients with large vessel occlusion undergoing endovascular treatment: A pooled analysis of individual patient data from mu… — PLoS Medicine 2026 8. PREVENT Equations: Implications for Stroke Prevention — Stroke 2026 9. Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review — Movement Disorders 2026 10. Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia — Annals of Neurology 2026 Listen at https://audioscholar.cc/episode/acm9ncpr8h

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Neurology — a weekly podcast briefing of the most significant peer-reviewed neurology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

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