93 episodes

Beginner's Mind with Christian Soschner is a show about breakthrough innovators, entrepreneurs, investors, thought leaders, and the stories behind their success. Christian Soschner invites the listeners to learn with him from the best and brightest minds behind disruptive businesses, innovative investments, prolific social movements, and technologies powering game-changing innovation. In intimate conversations, the host deconstructs the stories to help turn their wisdom into practical tactics you can use to improve your life, grow your business and help your community. Join the LSG2G Community: https://lsg2g.substack.com/

Beginner's Mind Christian Soschner

    • Business
    • 5.0 • 4 Ratings

Beginner's Mind with Christian Soschner is a show about breakthrough innovators, entrepreneurs, investors, thought leaders, and the stories behind their success. Christian Soschner invites the listeners to learn with him from the best and brightest minds behind disruptive businesses, innovative investments, prolific social movements, and technologies powering game-changing innovation. In intimate conversations, the host deconstructs the stories to help turn their wisdom into practical tactics you can use to improve your life, grow your business and help your community. Join the LSG2G Community: https://lsg2g.substack.com/

    #93: Thomas Schubert - The Role of Biophysics in Drug Development and Drug Discovery: What you Need to Know

    #93: Thomas Schubert - The Role of Biophysics in Drug Development and Drug Discovery: What you Need to Know

    What is the Role of Biophysics in Drug Development and Drug Discovery?

    In this episode, I speak with Dr. Thomas Schubert, CEO of 2bind, a provider of biophysical outsourcing solutions for the pharmaceutical. Dr. Schubert discusses the role of biophysics in drug development and the importance of outsourcing in the pharmaceutical industry.

    ⭐ In this episode, we talk about:
    The Role of Biophysics in Drug Development
    The Role of Biophysics in Antibody Research
    Success Stories in Biophysics
    The Development of the Life Science Industry in Europe from the Biophysicist's Perspective
    Future Trends in Drug Discovery and Drug Development

    ⭐ EPISODE Links:
    Today’s speaker is Thomas Schubert, CEO of 2bind

    Dr. Thomas Schubert received his Ph.D. in Biochemistry in 2012 from the University of Regensburg. Dr. Schubert joined 2bind in 2012 and was called for the CEO position in 2013. Dr. Schubert received the degree Betriebswirt (business economist) in 2014.

    Youtube

    📚 Book mentions in the episode:
    The Power Law
    Das Netzwerkunternehmen

    📖 Memorable Quotes:
    (04:30) “At 2bind, we are active with Webinars to educate people.”
    (08:15) “Biophysics is using physical measurement and interpretation to understand Biology"
    (24:40) “Many different changes in the environment of drug discovery occurred, and all of them pushed Biophysics.”
    (52:30) “Always employ people that are better than you”
    (01:29:27) “Biophysics will play a big role in Drug Discovery in 10 years”

    ⏰ Timestamps:
    (00:00) Intro 
    (02:00) Recap Bio Europe in Leipzig and Bio International in San Diego after the Pandemic Break
    (04:15) Integrating Social Media into Business Strategies
    (07:30) The Role of Biophysics in Drug Development
    (11:00) Background Thomas Schubert and 2bind
    (20:00) How has the Role of Biophysics in Drug Development evolved over the last 10 years
    (26:30) The Role of Biophysics in Antibody Research & Development
    (29:30) Biophysics and ADCs
    (33:00) 2bind’s position in the pharmaceutical value chain
    (38:30) How to combine scientific and development mindsets in the industry
    (43:30) Competition and Expertise in the Biophysics World
    (46:15) Technologies used in biophysical research projects
    (52:19) Challenges for Entrepreneurs Running a Deep Tech Service Business
    (56:30) Success Story #1: Lead Identification with 2bind
    (58:30) Success Story #2: Formulation Study with an HIV Vaccine Candidate
    (01:03:00) The Big Challenges for Pharma in this Century – Antibiotics, HIV, Cancer
    (01:10:00) The Development of the Life Science Industry in Europe 
    (01:17:00) Outsourcing – when is it the best solution for companies?
    (01:24:00) Future Trends in Drug Discovery and Drug Development from the Biophysicist’s Perspective
    (01:36:00) Epigenetics, AI, and Chess
    (01:43:00) How to Connect with Thomas Schubert



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    • 1 hr 46 min
    #92: Sebastian Mallaby - The Power Law - A Brief History of Venture Capital

    #92: Sebastian Mallaby - The Power Law - A Brief History of Venture Capital

    How did Venture Capital evolve? When did it start? Get the answers right here in the book The Power Law by Sebastian Mallaby.

    ⭐ In this episode, we talk about:
    • Storytelling Methods and a Writers Work Process
    • What is Venture Capital – From the Writers Perspective
    • How Did Silicon Valley Evolve into the Center of the Innovation World?
    • The 3 Most Crucial Moments in the Development of Venture Capital
    • The Future of the European Tech Eco-System
    • And much, much more

    ⭐ EPISODE Links:
    Today’s speaker is Sebastian Mallaby.
    Youtube

    📚 Book mentions in the episode:
    The Power Law

    📖 Memorable Quotes:
    (09:39) “In a Content Creators Economy where a lot of people spend a lot of time creating, it is worthwhile to spend 5 years writing a book”
    (12:46) “Do Venture Capitalists create innovation, or do they just show up for it?”
    (18:51) “Europe is fundamentally full of great engineers. It is a great market. Why wouldn’t it rival the United States if it got the right Venture Capital to take the risk.”
    (23:10) “The European culture is not as risk-friendly as the US. But it’s changing fast.”
    (27:45) “Genentech was the beginning of staged investments.”

    ⏰ Timestamps:
    (00:00) Speaker and Book Intro
    (02.25) Storytelling Methods and a Writer's Work Process
    (08:00) Development of the Methodology – From Nelson Mandela to Venture Capital
    (10:33) What is Venture Capital – From the Writer's Perspective
    (16:00) How Did Silicon Valley Evolve into the Center of the Innovation World?
    (19:39) Why Cover the Majority of the Stories about the US and Asia and very few stories about Europe?
    (27:41) The 3 Most Crucial Moments in the Development of Venture Capital
    (29:45) How Sequoia got into the hot tub with Atari
    (32:00) Softbank – Everybody Needs a 100 Million
    (39:00) Alibaba
    (43:45) The Future of Venture Capital
    (47:15) The Future of the European Tech Eco-System

    ⭐ Please support this podcast by checking out our partners: https://linktr.ee/lsg2g

    Sebastian Mallaby is the Paul A. Volcker senior fellow for international economics at the Council on Foreign Relations (CFR). An experienced journalist and public speaker, Mallaby contributes to a variety of publications, including Foreign Affairs, the Atlantic, the Washington Post, and the Financial Times, where he spent two years as a contributing editor. He is the author of five books, most recently The Power Law: Venture Capital and the Making of the New Future.



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    • 55 min
    #91: Marco Schmidt - AI in Drug Discovery and Drug Development: What You Need to Know

    #91: Marco Schmidt - AI in Drug Discovery and Drug Development: What You Need to Know

    What is the Role of Artificial Intelligence in Drug Development and Drug Discovery?

    ⭐ In this episode, we talk about:
    Deep Mind’s AlphafoldInvesting in Life Science companiesThe State of AI in Drug Development and Drug DiscoveryHow does GDPR limit the development of AI in Drug DiscoveryThe Human Genome and AIToday’s speaker is Marco Schmidt, CSO of Biotx.ai
    Marco had an exceptional academic career. He won the best PhD of the year award in Chemistry in his home country Germany and then went on to do a Post-Doc at the University of Cambridge.

    ⭐ EPISODE Links:
    Marco Schmidt on Linkedin
    Youtube

    📖 Quotes:
    (24:45) “Eroom's law is the observation that drug discovery is becoming slower and more expensive over time”
    (56:05) “We need more data”
    (58:13) “Biobanks provide the infrastructure that we really need in the future”
    (01:16:39) “Prediction Models of Type 2 Diabetes Have 99% Accuracy”
    (01:17:50) “There is no longevity gene. There are shortevity genes.”
    (01:53:45) “We are living in fantastic times”

    ⏰ Timestamps:
    (00:00) Kick Off and Intro
    (06:15) Deep Mind’s Alphafold
    (07:06) Background to Marco Schmidt and Biotx.ai
    (12:00) Business Model in AI for Drug Development – from Service Provider to Developer
    (13:15) Basic Definition of Drug Discovery and Drug Development for the Listeners of the Episode
    (17:20) For Retail Investors who have an eye on investing in public drug development companies: What is a Ligand?
    (20:09) Why is Drug Discovery Expensive and Lengthy?
    (23:30) Success and Failure Rate in Drug Development
    (24:30) What is erooms Law?
    (27:25) What is the right place for innovation? Startups or Big Corporations?
    (30:00) The Value Chain in the Pharma Industry – From Research to Marketed Products.
    (34:00) Investing in Life Science Companies
    (50:15) Why is Artificial Intelligence an Attractive Area?
    Speaker and Company
    (55:00) The State of AI in Drug Development and Drug Discovery – What is Science and What is Still Fiction.
    (58:00) Accessibility of Data – Is this the bottleneck in Artificial Intelligence Based Drug Discovery?
    (01:10:00) What would change in Drug Development if scientists could access healthy population data?
    (01:12:30) Prediction Models for Cancer, Alzheimer, and other diseases
    (01:16:00) Understanding the progression of diseases and the role lifestyle plays in AI
    (01:19:00) How does GDPR limit the development of AI in Drug Discovery
    (01:24:00) Data Curation in AI
    (01:28:45) Is Capital a Limiting Factor?
    (01:34:26) The Human Genome and AI
    (01:40:00) Is it possible to simulate the entire drug development process from lab to market?
    (01:46:00) Service Offerings of biotx.ai
    (01:51:30) How can AI help select the right patients?
    (01:59:00) Synthetic clinical trials
    (02:01:00) The Role of Excel in Machine Learning

    📚 Book Mentions:
    Drug Discovery and Drug Development
    The Power Law






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    • 2 hr 10 min
    #90: Brian Feroldi - Why Does the Stock Market go up?

    #90: Brian Feroldi - Why Does the Stock Market go up?

    Do you understand the dynamics of the stock market? Here is an episode with Brian Feroldi, Writer at the Motley Fool, on his new book “Why the stock market goes up?”

    We are talking about
    ⭐ The Global Problem With Financial Literacy
    ⭐ Why Did Brian Feroldi Write a Book About Investing for Beginners?
    ⭐ Why Does the Market Crash from Time to Time?
    ⭐ Cost Averaging and Index Investing – A Powerful Tool for People who don’t have time to diligently follow the market
    ⭐ What was Brian’s Biggest Investment Mistake?

    A basic understanding of the stock market is mandatory for every deep tech entrepreneur, business angel, and venture capitalist. A stock market is a place where companies can get more liquidity for scaling their business and provides an exit for early investors.

    Brian Feroldi describes the mechanics of the stock market in his latest book: Why does the stock market go up? I enjoyed his unique way of explaining complex economic situations in easy-to-understand layman’s terms.

    Brian Feroldi is a financial educator, YouTuber, and author. Since college, he has been intensely interested in money, personal finance, and investing.

    ⭐ EPISODE Links:
    Brian Feroldi on Youtube
    Youtube Video

    📖 Quotes:
    (05:31) "A lack of financial literacy is a global phenomenon"
    (14:50) "...it took me about 18 months to write it. ... I think we needed a book that explains in plain English what the stock market is - for beginners."
    (16:11) "If you look back on stock market history - it is very clear: Every ten years ... or so ... things go to hell!"
    (33:00) "Only Business Profits drive the Stock Market in any given direction"
    (43:53) "Investing in an Index Fund is totally fine for 99% of investors because they have no interest in reading SEC filings or doing research."
    (01:08:00) "Think Long-Term"
    ⏰ Timestamps:
    (00:00) Introduction
    (01:52) Why Deep tech Entrepreneurs Need a Basic Understanding of the Stock Market.
    (04:00) Brian Feroldi's studio
    (05:17) The Problem With Financial Literacy
    (06:35) How Brian got Into Investing?
    (08:00) The Motley Fool
    (10:05) Why Did Brian Feroldi Write a Book About Investing for Beginners?
    (15:00) Reflecting on the Tech Market Correction in 2022 and Other Stock Market Crashes
    (19:19) The 2000 and 2008 Crash Experience
    (23:20) Why Does the Market Crash from Time to Time?
    (27:50) Crowd Mentality, Market Timing, and Contrarian Investing
    (32:55) The 3 Major Forces That Drive the Stock Market Up
    (36:55) Why Should People Invest When Fear, Uncertainty, And Doubt are on the Market?
    (39:32) What were your biggest questions when you started investing?
    (43:25) Warren Buffetts S&P500 ETF Strategy for People who don't have time for market research
    (45:23) Cost Averaging and Index Investing – A Powerful Tool for People who don't have time to diligently follow the Market
    (48:00) What is Compounding?
    (51:11) What is the Magnitude of Stock Market Fluctuations
    (55:05) Brian Feroldi's on Cathie Wood's Ark Innovation Fund
    (01:00:00) What was B
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    • 1 hr 9 min
    #89: E Jane Caraway - Life Science in Georgia

    #89: E Jane Caraway - Life Science in Georgia

    Where are the Big Life Science Hubs in the United States? 

    Here is an in-depth overview of  Life Science In Georgia with many essential Key Facts and exciting stories from the beautiful state. My guest in this episode is E Jane Caraway, Director of Life Science at the Georgia Department of Economic Development.

    ⭐We are talking about
    Life Science, Vineyards, Vampires and ZombiesBoehringer Ingelheim's Facilities in AtlantaHow Life Science Companies Help CommunitiesScience in GeorgiaStarting a Life Science Company in Georgia as an Immigrant EntrepreneurAnd much, much more⭐About Georgia
    The state of Georgia is a dynamic hub for life sciences with more than 2,000 organizations. We have the resources to assist you in getting ideas researched, tested, commercialized, produced, and delivered quickly to most anywhere in the world. New and existing companies have access to a highly educated workforce, renowned research institutions, cutting-edge technological resources, and access to the global marketplace via a robust infrastructure. Georgia’s pro-business climate, combined with a culture of collaboration and innovation, has fostered growth across all sectors of life sciences.


    ⭐ EPISODE Links:
    E Jane Caraway: EJane Caraway, a passionate advocate for company success and community growth, has been with the Georgia Department of Economic Development for 13years. Since 2017 she has served as the Director of Life Sciences, and recently worked on projects with companies like Boehringer Ingelheim, Boston Scientific and IC Biomedical, just to name a few. 
    Youtube

    🎤 Quotes:
    (09:41) “Georgia has the second largest film industry in the world, after Canada and before Hollywood”
    (18:51) “The Soccer World Championship 2026 will be in the United States”
    (22:41) “Facebook has worked with local partnerships and entrepreneurs to build their own solar fields to supply energy to their facilities in Georgia”
    (28:41) "Georgia had a 150% growth in the Life Science Industry in 2021"

    🕛 Timestamps:
    (00:00) Intro
    (03:00) Recap of the #bio2022 in San Diego
    (05:35) Background EJane Caraway and Life Sciences in Georgia
    (08:00) What do Life Science, Canyons, Vineyards, Vampires, She-Hulk, King of Queens, and Zombies have in common?
    (10:00) The Film Industry in Georgia
    (15:30) Sports in Georgia – Baseball, Soccer, Football, Golf, Pickleball
    (21:30) Georgia’s Leading Industries – Coca Cola, Delta Airlines, NCR, Facebook, Boehringer Ingelheim, HomeDepot, Aflac, UPS
    (23:45) Boehringer Ingelheim in Atlanta, Georgia and Vienna, Austria
    (28:55) Life Science in Georgia has seen a 150% Growth Rate in 2022
    (33:00) The Positive Impact Life Science Companies Make in the Community – The Takeda Story
    (36:12) The Boston Scientific, AMRI and Gulf Stream – Ebola Story
    (41:21) Science in Georgia
    (44:30) Starting a Company in Georgia as an Immigrant Entrepreneur – How is the Workforce, Labspace, and Funding Situation in Georgia?
    (51:30) The Georgia Departme
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    • 1 hr 4 min
    #88: Jia En Chin, Shirley Lu, Thijs Spoor: New Opportunities for Biotechs in China

    #88: Jia En Chin, Shirley Lu, Thijs Spoor: New Opportunities for Biotechs in China

    What are the opportunities for Biotechs in the Chinese Market? Get answers to this question in this podcast with the BFC Group.

    ⭐We are talking about
    The BFC Group
    The Capital Market Landscape in China
    Deal Structuring in China
    Clinical Strategies for China
    Why Affordability and Accessibility of new drugs matter in China

    ⭐About BFC Group:
    BFC Group is a China-based investment banking firm with a focus on healthcare M&A, licensing, and financing.  We work with leading healthcare companies in the US, Europe, and Asia.  With first-hand operational experience in both the US and China, we have a deep understanding of the challenges our clients face when establishing or expanding their companies’ presence outside of their home market. 

    ⭐ EPISODE Links:
    Jia En Chin
    Thijs Spoor
    Shirley Lu:
    BFC Group:
    Youtube Presentation best viewed on Youtube

    🎤 Quotes:
    (26:04) “China is now the second largest pharma market in the world, Japan being third” 
    (31:11) “Many of our clients are still in Clinical Phase I, when they come to China”
    (33:29) “The China Market really rewards innovation in antibiotic research.”
    (48:30) “China takes care to make therapeutics accessible and affordable for the population”
    (51:24) “China's growing middle class wants to improve their quality of life.”
    (59:45) “Finding the right partner for a Go-To-China-Strategy is key to success. Otherwise, it can become very costly and might damage the asset.”
    (01:00:38) "... you want a personal connection, you want to educate and not sell..."
    (01:16:30) “In Q1/2022 18 new drugs were approved in China, 12 of them came from The West.”

    🕛 Timestamps:
    (00:00) Introductions
    (13:00) BFC Group Introduction to the Chinese Market
    (15:45) Capital Market Landscape in China
    (18:30) China Investment and Financing Trend
    (21:43) Licensing Deal Trends in China
    (25:00) Opportunities for Biotechs in China
    (25:45) The biggest Pharma Markets and Innovators  
    (30:00) Deal-Focus of Chinese Pharma Companies
    (32:00) The Therapeutic Focus in China in 2022
    (33:41) Antibiotics Research in China
    (36:40) The Major Player in Infectious Diseases and Cancer on the Chinese Market 
    (38:00) Market Potential in China for Chronic Diseases
    (39:55) The KBP Business Case
    (40:48) Patent Strategies for the Chinese Market
    (44:24) Important Points for Preparing a Market Entry in China
    (48:00) Price Dynamics and Reimbursement in China
    (49:30) Why Affordability and Accessibility Matters in China
    (50:30) The Necessary Data Packages for Market Entry in China
    (53:00) Clinical Strategies for Market Entry in China
    (56:30) Is a multi-center approach across several markets feasible in later-stage clinical trials?
    (01:01:30) Similarities and Differences in Culture, Communication
    (01:08:15) The Right approach for a Go-To-China Strategy
    (01:13:22) The Availability of Capital on Private and Public Marke
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    • 1 hr 18 min

Customer Reviews

5.0 out of 5
4 Ratings

4 Ratings

Smurfteer ,

Fantastic

Christian brings an extremely intelligent mind and deep curiosity to the podcast. When he interviews his guests he digs deep to not only glean the business gems they have to offer but who, as a person, they are as well. It brings a level of humanity to an excellent podcast. Highly recommend.

mherschberg ,

A great resources for life science entrepreneurship

If you want to be an entrepreneur in life sciences this podcast is a great way to get started. Christian knows the field well and brings on experts to help you learn.

Trevor Oldham ,

Awesome!

One of my new fav podcasts!

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