Bench to Bedside

The University of Kansas Cancer Center
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The University of Kansas Cancer Center's podcast Bench to Bedside provides a glimpse into the latest research discoveries that are transforming cancer care. Join Roy Jensen, MD, vice chancellor and director of the cancer center, weekly to hear from the top experts in the field as well as patients and caregivers.

  1. 4 NGÀY TRƯỚC

    Exploring the Obesity-Cancer Connection: A Pioneering Research Initiative

    In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, is joined by Dr. Kristy Brown and Dr. John Jakicic, co-leaders of KU Cancer Center's new Obesity, Metabolic Health & Cancer research program, the first of its kind at an NCI-designated cancer center focused on the obesity–cancer link. They discuss rising obesity rates, obesity's link to at least 13 cancers, and key biological mechanisms including insulin and glucose signaling, inflammation, and hormone changes such as estrogen. The guests explain how this new program will harmonize cancer and obesity research, study how changes in adiposity and tissue quality affect cancer risk and treatment response, and develop interdisciplinary, community-informed prevention and intervention strategies, including lifestyle approaches and newer obesity medications, to improve outcomes and survivorship. 00:00 Obesity and Cancer Link 01:03 Why KU Cancer Center Launched Program 03:47 How Obesity Fuels Cancer 05:57 Reversing Risk Questions 07:10 First of Its Kind Program 09:30 Obesity as the New Tobacco 10:35 Team Science and Partnerships 13:10 Patient Impact and Trials 16:46 Tissue Quality and Muscle 18:52 Next Decade Opportunities 21:31 Equity and Real-World Barriers 22:12 Evidence and Expert Validation 24:25 Closing and Resources Links from this Episode: ·       Learn more about the new Obesity, Metabolic Health & Cancer Research Program at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    25 phút

  2. 16 THG 4

    Collaboration and Community Trust: Tobacco Cessation Research at Swope Health

    In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, speaks with researchers Dr. Nikki Nollen and Dr. Lisa Sanderson-Cox about building lasting collaborations to reduce tobacco use and cancer disparities, particularly in African American communities. They describe how their partnership began at KU Medical Center and grew through a long-term, trusted collaboration with Swope Health, a federally qualified health center in Kansas City. Drs. Nollen and Cox explain how community and patient advisory boards shape their clinical trials, influencing study questions, counseling protocols, and attention to issues like menthol use, tobacco marketing, spirituality, and unmet social needs. They also highlight broader collaborations that advanced genetic and pharmacotherapy insights and helped inform higher-dose nicotine replacement approaches for lighter smokers, and they discuss e-cigarettes as harm reduction for adults but a risk for youth. 00:00 Welcome and Episode Focus 00:59 How Their Collaboration Began 01:54 Building Trust with Swope Health 03:24 Community Advisory Boards in Action 06:50 Letting the Community Lead 08:18 Unmet Social Needs and Study Design 10:28 Genetics and Broader Research Partners 12:09 Updating Nicotine Replacement Dosing 13:32 Lessons from Long Term Teamwork 15:40 E-Cigarettes Harm Reduction Debate 17:21 Closing Thanks and Takeaways Links from this Episode: ·       Learn more the partnership with Swope Health ·       Learn about Dr. Nikki Nollen ·       Learn more about Dr. Lisa Sanderson Cox ·       Learn more about research on e-cigarette usage To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    18 phút

  3. 1 THG 4

    Training the Next Generation of Translational Cancer Researchers: KU Cancer Center's K12 Program

    Dr. Roy Jensen introduces the season's focus on the people behind cancer research and hands hosting duties to Dr. Ronald Chen, chair of Radiation Oncology and associate director for Community Outreach and Engagement at The University of Kansas Cancer Center. Dr. Chen highlights the KU Cancer Center's K12 Paul Calabresi Career Development for Clinical and Translational Oncology program, which mentors and trains early career clinician-investigators, and interviews K12 scholar Dr. Yiduo Hu, a breast medical oncologist who joined KU after training at Yale and completing research and degrees at Case Western, Dana-Farber/Harvard, and Columbia University. Dr. Hu describes translational research as bridging communication between bench science and patient care, explains how the K12 Program's protected time and mentorship support his work on DNA damage repair and genome integrity in breast cancer, and discusses his newly activated pragmatic trial comparing two commonly used chemotherapy regimens for high-risk breast cancer. They also emphasize collaboration, including engagement with KU Cancer Center's PIVOT patient advocate group, to keep research patient-relevant and team-based. 00:00 Season Introduction 00:28 Guest Host Handoff 00:44 K12 Program Overview 01:18 Dr. Hu's Background 01:58 Translational Research Explained 03:08 K12 Support and Focus 04:09 Building A Clinical Trial 05:38 Protected Time Matters 06:22 Mentorship at KU Cancer Center 07:39 Community and PIVOT Collaboration 09:41 Career Reflections 10:33 Closing Thanks and Resources Links from this Episode: ·         Learn more about the K12 Paul Calabresi Career Development for Clinical and Translational Oncology Program To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    12 phút

  4. 24/12/2025

    Clinical Pharmacology: The Science Behind Safer, Smarter Cancer Therapies

    In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, interviews Dr. Brent Sear, director of the Clinical Pharmacology Shared Resource at KU Cancer Center. Brent shares his unique career journey into clinical pharmacology, the role of clinical pharmacology in advancing cancer therapies, and the critical work his team does in guiding clinical trials and personalizing cancer treatment. They also discuss emerging technologies and their potential impact on the future of cancer research. Tune in to learn more about the intricate processes that ensure safe and effective cancer therapies. 00:00 Introduction to the Podcast and Guest 01:06 Brent Sear's Journey into Cancer Research 03:21 Understanding Clinical Pharmacology 04:54 The Role of Clinical Pharmacology Shared Resource 06:40 Importance of Precise Measurement in Cancer Treatment 08:40 Collaborative Projects and Scientific Insights 09:55 Advice for Aspiring Researchers 11:52 Future of Clinical Pharmacology in Cancer Research 13:33 Conclusion and Farewell Links from this Episode: ·       Learn more about the Clinical Pharmacology Shared Resource at KU Cancer Center ·       Learn about Brent Sear, director of the Clinical Pharmacology Shared Resource ·       Learn about Shared Resources and Core Facilities at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    15 phút
  5. Looking Ahead: Hope and the Future of Cancer Research

    10/12/2025

    Looking Ahead: Hope and the Future of Cancer Research

    In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, hosts Dr. Kristy Brown, a nationally recognized expert in cancer metabolism and hormone signaling. Dr. Brown discusses the latest breakthroughs in understanding the relationship between obesity, estrogen, and cancer, along with how these discoveries shape more effective treatments. She reflects on her career and shares moving accounts of patient interactions that fuel her research. The conversation delves into emerging opportunities in cancer treatment and prevention, the role of artificial intelligence in research, and offers advice for early-career scientists on making a meaningful impact. Dr. Brown expresses optimism for future cancer research advancements and the potential for improved patient outcomes. 00:00 Introduction to the Podcast and Today's Topic 00:28 Meet Dr. Kristy Brown: Expert in Cancer Metabolism 01:02 Optimism in Cancer Research: Key Developments 02:31 Proud Moments in Cancer Research 04:15 Obesity, Metabolism, and Cancer: Emerging Discoveries 06:10 Translational Research: From Lab to Clinic 09:08 Advice for Early Career Scientists 12:18 Hope for the Future: Personal Reflections 13:24 Conclusion and Resources Links from this Episode: ·       Learn more about Dr. Kristy Brown ·       Learn about Dr. Brown's research ·       Learn about cancer prevention at KU Cancer Center To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    14 phút
  6. It Takes a Village: The Power of Cross-Disciplinary Collaboration in Cancer Research

    26/11/2025

    It Takes a Village: The Power of Cross-Disciplinary Collaboration in Cancer Research

    In this episode of Bench to Bedside, Dr. Roy Jensen speaks with Dr. Anna Arthur and Dr. Gregory Gan about their innovative cross-disciplinary work at the intersection of nutrition and radiation oncology. They explore how their combined expertise leads to holistic cancer treatment approaches, focusing on the effects of diet, inflammation, and treatment response on patient outcomes. Both experts share their personal and professional journeys into their respective fields, the collaborative projects they have undertaken, and the way they integrate multidisciplinary insights into improving cancer care. They also highlight their efforts to mentor the next generation of researchers, underscoring the value of collaboration in scientific innovation. 00:00 Introduction to Cross-Disciplinary Collaboration 00:41 Meet the Experts: Dr. Anna Arthur and Dr. Gregory Gan 00:48 Journey into Their Respective Fields 02:02 Challenges and Realizations in Cancer Research 05:22 The Intersection of Nutrition and Radiation Oncology 10:28 Collaborative Projects and Their Impact 19:31 Mentoring the Next Generation of Researchers 23:14 Future Directions in Integrating Nutrition and Cancer Treatment 25:04 Conclusion and Final Thoughts Links from this Episode: ·       Learn more about Dr. Anna Arthur ·       Learn about Dr. Gregory Gan ·       Learn about the Nutrition Shared Resource at the cancer center ·       Learn about head and neck cancer To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    27 phút

  7. 05/11/2025

    The Power of Patient Voices in Cancer Research

    In this episode of Bench to Bedside, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, talks with Marilyn Mahan and Karl Frees, members of Patient and Investigator Voices Organizing Together (PIVOT) – KU Cancer Center's patient research advocacy group – and co-chairs of the PIVOT Educational Task Force. They discuss PIVOT, an initiative bringing patients, survivors, caregivers, and researchers together to enhance cancer research. Marilyn and Karl share how PIVOT integrates patient perspectives into research, the ways advocates collaborate with researchers, and the program's impact on studies and researcher motivation. Both guests recount their personal cancer journeys and their dedication to influencing cancer research to become more patient-centered and effective. They stress the importance of patient advocacy, the empowerment that comes with shared knowledge, and the future goals of expanding PIVOT's reach and impact. 00:00 Introduction to Bench to Bedside 00:18 What is PIVOT? 02:03 How PIVOT Advocates Collaborate with Researchers 04:15 Impact of Patient Involvement on Research 06:34 Personal Cancer Journeys 13:53 Future Goals for PIVOT 18:58 Encouraging Advocacy and Involvement 21:17 Conclusion and How to Get Involved Links from this Episode: ·       Learn more about PIVOT and how to join ·       Learn about Lynch Syndrome ·       Learn about oral cancer ·       Follow PIVOT on Instagram To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    23 phút
  8. There's No Place Like Home

    22/10/2025

    There's No Place Like Home

    In this episode of the Bench to Bedside podcast, Dr. Roy Jensen, vice chancellor and director of The University of Kansas Cancer Center, speaks with Dr. Ronald Chen, chair of Radiation Oncology and associate director for Community Outreach and Engagement at KU Cancer Center. Dr. Chen shares his personal and professional journey from growing up in Topeka to Harvard and a career on the East Coast and back to Kansas, focusing on his motivation to return home and how his work impacts rural communities. He discusses his efforts in cancer care, telehealth and clinical trials, emphasizing the importance of bringing skills back to Kansas to improve local healthcare. 00:00 Introduction to Bench to Bedside 00:47 Meet Dr. Ron Chen 01:33 Dr. Chen's Educational Journey 03:41 Returning to Kansas 05:40 Advice for Young Kansans 07:19 Midwest Reflections 09:50 Addressing Rural Healthcare Challenges 12:35 Community Engagement and Partnerships 14:46 Balancing Clinical Care and Research 17:02 Future of Cancer Care at KU 19:30 Conclusion and Farewell Links from this Episode: ·       Learn more about Dr. Ronald Chen ·       Read this Q&A with Dr. Chen focused on eliminating health disparities ·       Learn more about community outreach and engagement at KU Cancer Center ·       Read about the Masonic Cancer Alliance To ensure you get our latest updates, follow us on the social media channel of your choice by searching for KU Cancer Center.

    20 phút
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Giới Thiệu

The University of Kansas Cancer Center's podcast Bench to Bedside provides a glimpse into the latest research discoveries that are transforming cancer care. Join Roy Jensen, MD, vice chancellor and director of the cancer center, weekly to hear from the top experts in the field as well as patients and caregivers.

Thông Tin

  • Nhà sáng tạo
    The University of Kansas Cancer Center
  • Năm hoạt động
    2021 - 2026
  • Tập
    91
  • Xếp hạng
    Sạch
  • Bản quyền
    © 2023
  • Trang web chương trình
    Bench to Bedside

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