Metabolic Mind

Bret Scher
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Metabolic Mind is working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. Metabolic interventions like ketogenic therapy are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. We explore topics that can help you understand how Metabolic Psychiatry might help you or a loved one treat mental disorders Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.

  1. -3 ДН.

    This Fat is Increasing Your Risk of Chronic Disease

    Could tackling visceral fat be the key to finally reversing the chronic disease crisis? Unlike the fat you see on your waistline, visceral fat hides deep inside your body, wrapping around organs like your liver, pancreas, and even your heart. And far from being inert, this fat acts like an inflammatory organ, fueling disease, undermining your immune system, and raising the risk of diabetes, cancer, and heart attacks. In this interview, Dr. Bret Scher sits down with Dr. Sean O’Mara, a physician with an extraordinary background (from undercover narcotics agent to Army ER doctor) who has spent over a decade studying visceral fat. Dr. O’Mara explains: 🐍 Why visceral fat is the true “head of the snake” driving chronic disease 🧪 How to detect it (and why most doctors ignore it) 💪 The surprising lifestyle interventions that can shrink it (fast). ⚠️Why visceral fat may be the single most dangerous and overlooked threat to your health It may fly under the radar, but visceral fat isn’t beyond reach. With the right tools and lifestyle changes, we can take back control of our health—and rewrite the future of chronic disease. Expert Featured: Dr. Sean O’Mara Website: https://drseanomara.com/Instagram: https://www.instagram.com/drseanomara/X: https://x.com/DrSeanOMara Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

    45 мин.

  2. 25 АВГ.

    The Truth About Treatment Resistant Depression: Part Three (Nutrition and Lifestyle)

    Despite decades of therapy and pharmaceutical use, most patients with major depressive disorder fail to achieve full relief. In part three of our series, Harvard-trained psychiatrist and nutrition specialist Dr. Georgia Ede shares why lifestyle interventions are actually some of the most powerful tools we have for fighting treatment resistant depression. Drawing on years of clinical practice and pioneering work in metabolic psychiatry, Dr. Ede explains how metabolic health, sleep, exercise, circadian rhythm, and nutrition directly influence brain energy. She also breaks down why nutrition (especially carbohydrate restriction and ketogenic diets) hold unique promise for restoring brain function, even in people who haven’t responded to conventional treatments like medication and therapy. This conversation covers: How treatment-resistant depression is tied to brain metabolismThe role of exercise intensity in improving symptomsHow sleep and circadian rhythm shape brain healthHow nutrition is the #1 lever for change Clinicians, researchers, and individuals navigating depression: this conversation is a powerful reminder that patients have more power than they’ve been led to believe and deserve to know the full spectrum of tools available to them. Lifestyle interventions shouldn’t be “secondary”—they’re foundational. Check out Metabolic Mind's model for metabolic psychiatry to learn more. 📌 In case you missed episode 1 and 2 of our 3-part Treatment Resistant Depression series: Episode 1: Breaking the Myth: https://youtu.be/q7jg6wlD6gYEpisode 2: TMS & Psychedelics: https://youtu.be/ay4RjudumHw Expert Featured: Dr. Georgia Ede Website: https://www.diagnosisdiet.com/Book: https://www.diagnosisdiet.com/change-your-diet-change-your-mindYouTube: ‪@GeorgiaEdeMD‬X: https://x.com/GeorgiaEdeMDIG: https://www.instagram.com/georgiaedemd/ CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between...

    29 мин.

  3. 20 АВГ.

    The Truth About Treatment-Resistant Depression: Part Two (TMS and Psychedelics)

    Treatment-resistant depression can feel like the end of the road, but there are more options than most people realize. Beyond traditional antidepressants, a range of innovative treatments exist, including: Electroconvulsive therapy (ECT)Repetitive Transcranial magnetic stimulation (rTMS)Vagus nerve stimulationRapid-acting compounds like ketamine, esketamine, and psilocybin These treatments are offering new hope for patients who haven’t found relief in the current standard of care. In this second part of our three-part series, Dr. Georgia Ede and Dr. Bret Scher dive deep into the science, effectiveness, and practical considerations of these approaches. You’ll learn how these treatments work, the evidence behind them, and what to expect in terms of accessibility, cost, and side effects. From the rapid results of ketamine (sometimes within a single day) to the growing public awareness of rTMS, this discussion explores both cutting-edge and underutilized options, plus the barriers that still keep many from accessing them. Watch now to discover why “treatment-resistant” doesn’t mean “hopeless,” and be on the lookout for Part 3, where we’ll explore powerful (and accessible) lifestyle and metabolic interventions that can complement or even replace medical treatments. Expert Featured: Dr. Georgia Ede Website: https://www.diagnosisdiet.com/Book: https://www.diagnosisdiet.com/change-your-diet-change-your-mindYouTube: ‪@GeorgiaEdeMD‬X: https://x.com/GeorgiaEdeMDIG: https://www.instagram.com/georgiaedemd/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

    27 мин.

  4. 19 АВГ.

    What Doctors Really Think About the ‘Miracle’ Weight Loss Drugs

    GLP-1 medications like Ozempic, Wegovy, and Mounjaro have become household names, celebrated as breakthrough treatments for weight loss and obesity. But while headlines showcase dramatic before-and-after photos and promises of rapid transformation, when we step beyond the marketing, a more nuanced reality comes to light. In this candid conversation, Dr. Mark Cucuzzella, a family medicine physician, and Dr. Tro Kalayjian, board-certified in internal and obesity medicine, draw on decades of clinical experience to examine where GLP-1s truly shine, where they fall short, and why the foundation for lasting health can’t come from a prescription alone. They make the case for integrating GLP-1s into a comprehensive care plan, one that addresses nutrition, movement, sleep, and stress. Without these pillars, patients face higher risks of side effects, reduced long-term benefits, and the all-too-common rebound weight gain. In this interview, you’ll learn: Which patients benefit most from GLP-1 therapy (and which may not)How “medication stewardship” ensures safe, responsible useWhy starting at the lowest effective dose and tapering mattersHow lifestyle-first programs can match or exceed drug results at a fraction of the cost Drs. Cucuzzella and Kalayjian remind us that true success lies in restoring metabolic health and building habits that last long after the injection ends. GLP-1 medications can be powerful allies, but they’re not a silver bullet. Without a foundation of nutrition, movement, sleep, and stress management, they risk becoming just another short-term fix. Expert Featured: Dr. Mark Cucuzzella Website: https://www.drmarksdesk.com/ Dr. Tro Kalayjian Website: https://toward.health/IG: https://www.instagram.com/doctortro/X: https://x.com/DoctorTro Resources Mentioned: TOWARD: a metabolic intervention that improves addiction and binge eating symptoms https://doi.org/10.3389/fpsyt.2025.1612551 CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education,...

    44 мин.

  5. 13 АВГ.

    The Truth About Treatment Resistant Depression: Part One (Breaking the Myth)

    What is treatment resistant depression and perhaps more importantly, what does it say about the ineffective care many receive? Treatment-resistant depression (TRD) is defined as major depressive disorder (MDD) that fails to respond to at least 2 anti-depressant medications. Nearly 10% of the adult population in the U.S. experience a major depressive episode each year. The numbers in our youth are even more alarming with some studies suggesting that between 40-50% of college-aged students are living with depression. While anti-depressant medications tend to be the first-line treatment for MDD, as Dr. Georgia Ede highlights, “it’s more common not to respond to standard antidepressants than it is to respond to them.” This makes TRD the “norm”, but the name itself is misleading. It doesn’t mean your brain is broken or that you’ve run out of options. In fact, it says more about the limits of our current standard of treatments than about you. In this first episode of a three-part series, cardiologist Dr. Bret Scher sits down with Harvard-trained psychiatrist @GeorgiaEdeMD‬ to unpack what treatment-resistant depression really means, why it’s more common than most people think, and why the term can be so harmful. In this episode, you’ll learn: How depression is diagnosedThe surprising prevalence of TRDWhy antidepressants often fail to deliver lasting reliefThe biological factors (from inflammation to metabolic dysfunction) that may be driving MDDThe importance of broadening the treatment toolbox beyond medication If you or someone you love has been labeled with “treatment-resistant” depression, this conversation is an important reminder: there are other options to explore, and more importantly, there is hope. Be on the lookout for episode 2 of this 3-part TRD series, where Dr. Scher and Dr. Ede cover alternative treatments and cutting-edge therapies including neurostimulation, psychedelic-assisted therapy, and metabolic interventions that could offer new hope. Expert Featured: Dr. Georgia Ede Website: https://www.diagnosisdiet.com/Book: https://www.diagnosisdiet.com/change-your-diet-change-your-mindYouTube: ‪@GeorgiaEdeMD‬X: https://x.com/GeorgiaEdeMDIG: https://www.instagram.com/georgiaedemd/ Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can...

    25 мин.

  6. 11 АВГ.

    6 Clear Signs You Might Have Food Addiction & What You Can Do

    Is food addiction a mental illness? Should ultra-processed foods rich in sugar and refined carbohydrates be classified alongside alcohol, nicotine, and other addictive substances linked to substance use disorders? Food addiction (especially to processed, packaged, carb-heavy foods) is real, widespread, and often misunderstood by both the public and healthcare professionals. Dr. Bret Scher and Dr. Georgia Ede sit down with Dr. Jen Unwin, a psychologist with over 30 years of NHS experience, to explore the science, diagnostic challenges, and recovery strategies for ultra-processed food addiction. In this interview, you’ll learn: Why food addiction isn’t yet formally recognized as a substance use disorderHow food addiction differs from emotional or disordered eatingBiological mechanisms driving addictive patterns, such as dopamine spikes from refined carbohydratesThe six WHO criteria for substance use disorder and how they apply to foodThe role of ketogenic and low-carb diets in recovery from food addictionThe influence of artificial sweetenersThe importance of defining the addictive substances involved You’ll hear practical strategies for treatment, including abstinence-based approaches, personalized dietary plans, group support, and brain-retraining education. The conversation also explores the rise of GLP-1 medications—where they can help, where they fall short, and how they compare to dietary interventions in addressing root causes. If you or your patients struggle with cravings, cycles of relapse, or feelings of helplessness around food, this discussion offers hope, clarity, and actionable next steps toward lasting recovery. Expert Featured: Dr. Jen Unwin https://x.com/drjenunwinwww.the-chc.org Dr. Georgia Ede ‪@GeorgiaEdeMD‬ Resources Mentioned: The International Food Addiction Conference www.the-chc.org/fas/conference Dr. Unwin’s Book https://www.amazon.com/Fork-Road-Hopeful-Guide-Freedom-ebook/dp/B08XZL1LLJ/ CME’s Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between...

    57 мин.

  7. 7 АВГ.

    Q&A’s: Are Sweeteners Helpful or Harmful? Dairy? Ketone Levels, Longevity, and More

    Ketogenic therapy for mental health is gaining traction, but what happens when it doesn’t seem to work or even makes things worse? In this episode, Dr. Georgia Ede and Dr. Bret Scher answer some of the most common questions about ketogenic diets, including what to do when your mental health doesn’t improve, how to properly enter ketosis, and why sweeteners, snacks, and dairy might be holding you back. They break down the difference between a ketogenic diet and ketogenic therapy, and why things like ketone levels, medication adjustments, and lifestyle factors matter. You’ll also learn why some people experience initial worsening symptoms, how to transition more gradually, and when to seek support from experienced clinicians. From food choices to long-term outcomes, this episode covers key troubleshooting strategies for making ketogenic therapy work for your brain and body. Have questions about ketogenic therapy and mental health? Drop them in the comments, we’d love to hear from you! Expert Featured: Dr. Georgia Ede Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

    28 мин.

  8. 4 АВГ.

    Do We Have Kidney Health All Wrong?

    Is high protein intake responsible for chronic kidney disease? Have you ever heard that ketogenic diets are harmful to your kidneys? These are just a few of the common kidney health myths debunked in this interview with Dr. Thomas Weimbs, who says that traditional views on what causes chronic kidney disease are “definitely not founded in science.” Dr. Thomas Weimbs, professor and vice chair at UC Santa Barbara, has spent decades studying chronic kidney disease (CKD). His recent research explores the impact of ketogenic interventions on kidney function, and the findings may surprise you. Rather than harming the kidneys, Dr. Weimbs is finding that keto can actually improve kidney function in people living with CKD. According to Dr. Weimbs, “Clearly, the number one cause of chronic kidney disease is not protein in excess—it’s, of course, carbohydrates in excess and type 2 diabetes. Insulin resistance is causing chronic kidney disease.” In this episode, you’ll learn: Why longstanding myths about protein and kidney function need to be re-examinedWhy misconceptions around keto and kidney health existHow ketogenic diets are showing promise for chronic kidney disease (including PKD)About results from randomized controlled trials and the 2-year Virta Health studyHow ketones may directly benefit kidney health Dr. Weimbs also shares insights from his lab’s ongoing research—findings that challenge conventional thinking and call for a re-examination of how we understand and treat chronic kidney disease. Expert Featured: Dr. Thomas Weimbshttps://www.facebook.com/groups/256099897773551/https://santabarbaranutrients.com/ CMEs Mentioned: Managing Major Mental Illness with Dietary Change: The New Science of Hope https://www.mycme.com/courses/managing-major-mental-illness-with-dietary-change-9616 Brain Energy: The Metabolic Theory of Mental Illness https://www.mycme.com/courses/brain-energy-the-metabolic-theory-of-mental-illness-9615 Follow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry. Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/ About us: Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them. Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

    32 мин.
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Metabolic Mind is working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. Metabolic interventions like ketogenic therapy are being used to treat serious mental illnesses like Bipolar Disorder, Schizophrenia, and Major Depressive Disorder. We explore topics that can help you understand how Metabolic Psychiatry might help you or a loved one treat mental disorders Watch our videos at https://www.youtube.com/@metabolicmind Our channel is for information only. Consult your physician before changing your lifestyle or medications.

Информация

  • Автор
    Bret Scher
  • Годы выхода
    2023 - 2025
  • Выпуски
    130
  • Ограничения
    Без ненормативной лексики
  • Авторские права
    © Bret Scher, MD FACC
  • Сайт подкаста
    Metabolic Mind

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