CGT Square Talk

Anthony Roth & Armen Gasanyan

On CTG Square Talk we dive into educational topics and explore ways to improve business systems and processes. Our aim is to provide our audience with practical knowledge and actionable takeaways they can implement in their own projects. We hope you can learn something from our conversations.

  1. 2D AGO

    CGT Square Talk - Agentic AI Explained: Models, Costs & Security Risks | Part 2

    Part 2 of our AI series dives deeper into what’s actually powering agentic AI systems, the models behind the scenes. In this episode, the team breaks down how different models are used across AI agents, why a model strategy is critical, and how cost, performance, and reliability all play into real-world implementations. We also explore: Why using a single model isn’t scalable How fallback models prevent downtime The real cost of APIs vs subscriptions Why human-in-the-loop is still essential And a major AI-driven security breach that highlights new risks companies face Whether you're building with AI or just trying to understand how these systems actually work in production, this episode gives you a grounded, behind-the-scenes look. Stay tuned for Part 3, where we’ll walk through a live demo and share practical tips & workflows. 00:00 – Intro & Recap of Part 1   00:54 – What AI Models Actually Do (The “Brains”)   02:01 – Why Model Strategy Matters   03:30 – Cost Considerations & Token Limits   05:02 – Primary vs Fallback Models Explained   07:30 – Real Issues Switching Between Models   09:44 – Trial & Error: Choosing the Right Model   10:38 – When AI Gets It Wrong (Fake Sources Example)   11:27 – Matching Models to Tasks (Research vs Coding)   12:50 – Human-in-the-Loop: Why It’s Critical   15:07 – AI in Development: Junior vs Senior Engineers   16:47 – Where AI Fits in the SDLC   18:48 – AI as a Tool, Not a Replacement   20:32 – Strategy Before Implementation   21:06 – Real Model Stack (What They Actually Use)   23:49 – Subscription vs API Cost Breakdown   26:01 – Real Example: $100 API Cost in One Day   27:30 – Cheaper Model Alternatives (AWS, Open Models)   28:54 – The Future of AI Cost Optimization   32:54 – Enterprise vs Open Source Models   34:33 – Compute Power & Infrastructure Realities   35:59 – Why Design Matters Before Building AI   37:39 – From Experimentation to Architecture   40:20 – The “Skunkworks” Approach to AI   41:40 – Major AI Security Risks (Real Breach Case)   42:37 – How AI Can Exploit APIs   44:25 – Why This Security Threat Matters   46:55 – Is Software Security Falling Behind?   49:59 – Why Traditional Pen Testing Isn’t Enough   51:19 – AI vs Human Security Testing   52:51 – What’s Coming in Part 3 (Demo + Tips) CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    54 min

  2. APR 14

    CGT Square Talk - Agentic AI Explained: Building Real Software with Autonomous Agents | Part 1

    AI isn’t just a buzzword anymore; it’s actively reshaping how software gets built. In this episode of CGT Square Talk, we sit down with Kenny Gibbons to break down how we used agentic AI to automate parts of the software development lifecycle and actually built a working feature in just a few hours. From security concerns and “blast radius” thinking to real-world implementation inside a regulated pharma environment, this is a candid look at what AI can (and can’t) do today. 💡 In Part 1, we cover: What agentic AI actually is (and why it matters) The risks of open-source AI tools How we set up guardrails and “mission control.” Training AI agents to understand real systems The future of AI in regulated industries 👉 In Part 2, we go deeper into scaling this approach and what it means for the future of work. 00:00 – Intro & Why AI Is Back on the Agenda 00:46 – Meet the Team & Backgrounds 02:17 – What Is Clawbot / OpenClaw? 03:10 – Armin’s Technical Background & Journey 04:32 – Why Agentic AI Is a Big Deal 06:35 – Security Risks: “Anyone Can Download This” 07:35 – Guardrails & Controlling the “Blast Radius” 10:08 – What Is Agentic AI (Explained Simply) 12:25 – Balancing Innovation vs. Control 13:43 – Setting Up the System (VPS + Security) 15:35 – Building “Mission Control” for AI Agents 19:12 – Why Architecture Matters More Than Just Spinning Up Agents 23:07 – Where AI Fits in the Software Development Lifecycle 26:20 – Hybrid Agile + Compliance (Pharma Reality) 30:03 – Deciding What Should (and Shouldn’t) Be Automated 31:48 – Training the AI Agents 34:21 – Teaching AI Compliance (CFR 21 Part 11) 36:56 – The Power of Autonomous Learning 39:09 – Will AI Change Regulation? 41:06 – The Future: AI in the FDA & Compliance 45:16 – How We Trained the Developer Agent 47:32 – Building the Full AI Workflow 49:08 – Human Checkpoints & Safeguards 51:41 – Running the First Real Test 53:07 – Building a Feature in 3 Hours 54:16 – AI Finding Its Own Bugs (and Yours) 57:25 – Risks, Hallucinations & Control 1:00:01 – Building Internal Tools with AI 1:04:18 – Will AI Replace SaaS? 1:07:24 – The Risks of Democratizing Software 1:10:05 – Final Advice: Don’t Take the Leash Off Yet CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    1h 12m

  3. 03/31/2025

    Episode 14 - Christian Fuchs

    In this episode, we explore key system considerations in Cell & Gene Therapy with Christian Fuchs, Head of Orchestration and Exceptions Management for Cell & Gene Therapy. Christian brings deep global expertise to the conversation and is responsible for building and leading the operational business capabilities that support the “virtual treatment journey”—orchestrating the data, transactions, and documents that enable CGT delivery in both clinical and commercial settings. CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    39 min

  4. 03/10/2025

    Ep. 13 - Cyrus Tosun (Pt. 2)

    Welcome back for part 2! This week dive back into the Enneagram with our guest and Certified Integral Coach Cyrus Tosun Emotional Intelligence is the key to successful collaboration. Cyrus, with over 10 years experience in coaching and leadership development, gets the team to explore successful ways of working with different personality types and share some of their own stories. Cyrus with his calm style has a knack for helping people unlock their true potential and create thriving, meaningful careers. He’s also a Faculty member at New Ventures West, where he mentors future coaches and offers expertise in executive coaching.  Join us on this interesting ride and see how you can apply the Enneagram and Cyrus’ approach to successful collaboration in a dynamic environment like CGT. CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    43 min

  5. 02/24/2025

    Episode 12 - Cyrus Tosun (Pt. 1)

    This week join the BlueSquared team as they delve into their Enneagram personalities with our guest and Certified Integral Coach Cyrus Tosun Emotional Intelligence is the key to successful collaboration. Cyrus, with over 10 years experience in coaching and leadership development, gets the team to explore successful ways of working with different personality types and share some of their own stories. Cyrus with his calm style has a knack for helping people unlock their true potential and create thriving, meaningful careers. He’s also a Faculty member at New Ventures West, where he mentors future coaches and offers expertise in executive coaching.  Join us on this interesting ride and see how you can apply the Enneagram and Cyrus’ approach to successful collaboration in a dynamic environment like CGT. CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    34 min

  6. 10/28/2024

    Episode 11 - The Power of Collaboration in Cell and Gene Therapy

    In this episode of CGT Square Talk, the BlueSquared team—Anthony, Ian, Gary, and Armen—delve into the critical role of collaboration in the Cell and Gene Therapy space. Focusing on the systems and processes that drive success, they explore how teamwork enhances operational efficiency and accelerates innovation. From streamlining workflows to optimizing cross-functional efforts, collaboration is key to unlocking new possibilities. Join us as we discuss practical approaches to building stronger partnerships and fostering collaboration that can transform the industry. CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    32 min

  7. 10/14/2024

    Episode 10 - Julia Zats

    In today’s episode, we are excited to welcome Julia Zats, a senior IT executive with over 25 years of experience managing and enabling high-performance teams. With deep expertise in developing global IT strategies and implementing systems that support commercialization, Julia has been instrumental in driving success across the cell and gene therapy space. She shares her insights on the importance of collaboration in clearing roadblocks and enabling teams to thrive in this rapidly evolving industry. We also explore how tools like the Enneagram system for personality types can enhance team dynamics, streamline communication, and make teams work more effectively together. Join us for an engaging conversation on fostering collaboration and maximizing team potential in a highly specialized field. Enneagram Link: https://www.enneagraminstitute.com/ David and Goliath by Malcom Gladwell: https://www.amazon.com/David-Goliath-Underdogs-Misfits-Battling/dp/0316204374 CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    43 min

  8. 09/30/2024

    Episode 9 - B2 LSX Boston 2024 Conference Recap

    Today, we’re sitting down with our BlueSquared team to recap our time at the LSX Conference in Boston. From startup funding and patient access to collaboration and AI, we’ll dive into the key takeaways shaping the future of healthcare. Let’s get into it! CGT Square Talk Hosted by: Anthony Roth & Armen Gasanyan  New episodes every other Monday!

    28 min
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Ratings & Reviews

5
out of 5
4 Ratings

About

On CTG Square Talk we dive into educational topics and explore ways to improve business systems and processes. Our aim is to provide our audience with practical knowledge and actionable takeaways they can implement in their own projects. We hope you can learn something from our conversations.

Information

  • Creator
    Anthony Roth & Armen Gasanyan
  • Years Active
    2024 - 2026
  • Episodes
    16
  • Rating
    Explicit
  • Copyright
    © 2026 CGT Square Talk
  • Show Website
    CGT Square Talk