Chronic Insights

James Allen

For spoonies, for the chronically ill, for people with autoimmune disease, arthritis, fibromyalgia, EDS, axial spondyloarthritis / ankylosing spondylitis, endometriosis, migraine, POTS or any of the thousand other health conditions which cause chronic pain and fatigue. I'm James Allen, the developer of the Chronic Insights symptom diary app, author of Poetry For Spoonies, veteran spoonie, and AS lifer - grab your duvet, pillow, hot water bottle, meds and headphones as we relax together and shut the world out while we talk about spoonie life and feel less alone, together.

Episodes

  1. Endogenous opioids: the body's own painkillers (RE-UPLOAD)

    07/14/2023

    Endogenous opioids: the body's own painkillers (RE-UPLOAD)

    If you have chronic pain, you need to listen to this episode! Did you know that the body creates it's own opioids? Learn what they are, how they work, how they relate to synthetic opioids, why tolerance and dependence happens and what the future might have in store for next-generation pain medicines Episode transcript⁠ ⁠Follow and DM me on Instagram⁠ Email me at james@chronicinsights.com Get the Chronic Insights symptom diary app ⁠for Android⁠ and ⁠for iOS References: Treating Pain without Pills - Scientific American    Opioid crisis: powerful but non-addictive drug could replace morphine | New Scientist    The new pain treatments that may finally stem the need for opioids | New Scientist    Body’s 'Natural Opioids' Affect Brain Cells Much Differently than Morphine | UC San Francisco (ucsf.edu)    Frontiers | Endogenous opioid systems alterations in pain and opioid use disorder (frontiersin.org)    Scientists Take Another Step Toward Creating Better Pain Medications | Newsroom (unchealthcare.org)    Endocannabinoids and exercise - PMC (nih.gov)    Wired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the ‘runner’s high’ | Journal of Experimental Biology | The Company of Biologists    Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons | Nature Neuroscience    Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia | Journal of Medical Genetics (bmj.com)

    37 min
  2. Nociceptors: how pain is transmitted in the body

    06/22/2023

    Nociceptors: how pain is transmitted in the body

    Studies show that learning how chronic pain works can actually make it easier to cope? The first of a series of episodes explaining the science behind pain, chronic pain, why pain goes wrong, why it doesn't go away, how emotion, anxiety, expectations and other things can affect how we experience chronic pain, and what we can do to feel more empowered over it. Plus, some updates about the Chronic Insights symptom diary, and my upcoming book Poetry for Spoonies. Episode transcript⁠ ⁠Follow and DM me on Instagram⁠ Email me at james@chronicinsights.com Get the Chronic Insights symptom diary app ⁠for Android⁠ and ⁠for iOS Cortical homunculus - Wikipedia  A great class lecture for chronic pain patients: Explain Pain | Mid-Columbia Medical Center (mcmc.net)  Studies which showed Pain Neuroscience Education (PNE) did NOT help: Effect of Additional Pain Neuroscience Education in Interdisciplinary Multimodal Pain Therapy on Current Pain. A Non-Randomized, Controlled Intervention Study - PubMed (nih.gov)  Studies which showed that it DID help:  Embedding pain neuroscience education in the physical therapy management of patients with chronic plantar fasciitis: a prospective case series - PubMed (nih.gov)    [Effectiveness of pain neuroscience education in patients with fibromyalgia: Structured group intervention in Primary Care] - PubMed (nih.gov)    Pain Neuroscience Education Combined with Therapeutic Exercises Provides Added Benefit in the Treatment of Chronic Neck Pain - PubMed (nih.gov)    Effects of combining manual therapy, neck muscle exercises, and therapeutic pain neuroscience education in patients with migraine: a study protocol for a randomized clinical trial - PubMed (nih.gov)    Effectiveness of a structured group intervention based on pain neuroscience education for patients with fibromyalgia in primary care: A multicentre randomized open-label controlled trial - PubMed (nih.gov)    Effect of Pain Neuroscience Education Combined With Cognition-Targeted Motor Control Training on Chronic Spinal Pain: A Randomized Clinical Trial - PubMed (nih.gov)    [Effectiveness of education based on neuroscience in the treatment of musculoskeletal chronic pain] - PubMed (nih.gov)    The effectiveness of training physical therapists in pain neuroscience education on patient reported outcomes for patients with chronic spinal pain: a study protocol for a cluster randomized controlled trial - PubMed (nih.gov)    Pain Neuroscience Education and Physical Therapeutic Exercise for Patients with Chronic Spinal Pain in Spanish Physiotherapy Primary Care: A Pragmatic Randomized Controlled Trial - PubMed (nih.gov)    Pain Neuroscience Education Plus Usual Care Is More Effective Than Usual Care Alone to Improve Self-Efficacy Beliefs in People with Chronic Musculoskeletal Pain: A Non-Randomized Controlled Trial - PubMed (nih.gov)

    44 min

About

For spoonies, for the chronically ill, for people with autoimmune disease, arthritis, fibromyalgia, EDS, axial spondyloarthritis / ankylosing spondylitis, endometriosis, migraine, POTS or any of the thousand other health conditions which cause chronic pain and fatigue. I'm James Allen, the developer of the Chronic Insights symptom diary app, author of Poetry For Spoonies, veteran spoonie, and AS lifer - grab your duvet, pillow, hot water bottle, meds and headphones as we relax together and shut the world out while we talk about spoonie life and feel less alone, together.