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  1. 21h ago

    The A$2.2B Myricx Bio Deal, AI's Healthcare Land Grab and Preventive Health

    Novartis has agreed to acquire Myricx Bio for up to US$1.5 billion, approximately A$2.2 billion, in a major outcome for a UK biotech company with deep Australian venture backing. In the inaugural What the Health Wrap, host Emily Casey is joined by Dr Jackie Rabec, co-founder and Chief Product Officer at ThinkMD.ai, and Dr Prashanth Rajan, Associate at Brandon Capital, to work through what the fortnight's biggest healthcare stories actually mean. Prashanth explains how Myricx Bio evolved from small-molecule science into a new class of antibody-drug conjugate payloads. He discusses why the proposed acquisition matters for cancer therapeutics, investors and Australia's biotech ecosystem, while cautioning that the ultimate test will still come through clinical development. The conversation then turns to artificial intelligence. Jackie argues that healthcare companies need more than a powerful model. They need a genuine problem, sustainable economics, clinical workflow integration and the change management required for adoption. Prashanth applies the same test to AI drug discovery, where molecular designs must still survive laboratory testing and clinical trials. The panel also examines proposed changes to Australia's R&D Tax Incentive. Under the current proposal, the offset would be refundable for eligible businesses younger than ten years and non-refundable for older businesses. Prashanth explains why that distinction could affect biotech companies just as expensive clinical programs begin to scale, potentially pushing investment, clinical activity and company growth offshore. AdvanCell's US$315 million Series D offers a timely example of what sustained local support can produce. The company is advancing a Lead-212 targeted alpha therapy for metastatic prostate cancer while expanding its isotope supply and manufacturing infrastructure. Finally, the panel asks whether preventive health and longevity represent the future of care or another layer available mainly to people who can afford it. Everlab's A$65 million Series A and Neko Health's US$700 million Series C demonstrate growing demand, but questions remain about equity and whether earlier intervention can reduce pressure on public healthcare systems. GuestsDr Jackie Rabec is co-founder and Chief Product Officer at ThinkMD.ai, which builds offline-capable clinical decision-support tools for frontline health workers. She previously worked at Google and was Head of Product at Heidi Health. Dr Prashanth Rajan is an Associate at Brandon Capital and leads its activities in New South Wales. He has a background in bioinformatics, biochemistry and molecular biology. Chapters00:00 Introducing the What the Health Wrap 08:07 Myricx Bio's proposed US$1.5 billion acquisition 11:13 Antibody-drug conjugates and Australian biotech 15:35 AI in healthcare beyond administration 24:50 The promise and limits of AI drug discovery 28:46 Proposed changes to Australia's R&D Tax Incentive 35:22 AdvanCell's US$315 million Series D 42:25 Preventive health, longevity and primary care 53:28 Rapid fire: platform risk, companies to watch and useful resources Links and resourcesThinkMD.ai: https://www.thinkmd.ai/ Dr Prashanth Rajan at Brandon Capital: https://brandoncapital.vc/team_member/prashanth-rajan/ Myricx Bio acquisition announcement: https://brandoncapital.vc/2026/07/06/brandon-capital-announces-agreement-for-novartis-to-acquire-portfolio-company-myricx-bio-to-advance-new-class-of-cancer-therapeutics/ Australian Treasury's R&D Tax Incentive proposal: https://treasury.gov.au/sites/default/files/2026-06/p2026-781365_0.pdf Claude for Healthcare: https://www.anthropic.com/news/healthcare-life-sciences Chai Discovery's US$400 million Series C: https://www.chaidiscovery.com/news/series-c AdvanCell's US$315 million Series D: https://svhealthinvestors.com/news/advancell-closes-us-315-million-oversubscribed-series-d-financing-to-advance-targeted-alpha-therapies-and-expand-clinical-and-commercial-manufacturing-infrastructure Everlab: https://www.everlab.com.au/ Neko Health's US$700 million Series C: https://www.nekohealth.com/se/en/press/neko-health-raises-usd700m-series-c-ahead-of-us-launch About the hostEmily Casey is the founder of What the Health and host of the What the Health Wrap, making major developments in health technology and innovation easier to understand. The What the Health Wrap is brought to you by What the Health in partnership with Tenmile Ventures. What the Health is part of Day One Network, the podcast and media network from W2D1 Media: https://dayone.fm/

    The A$2.2B Myricx Bio Deal, AI's Healthcare Land Grab and Preventive Health
  2. Trailer

    Introducing What The Health with Emily Casey | Official Trailer

    Five years of health innovation coverage, millions of reads, and a community of 11,000+. Now finally, What the Health has a podcast too — bringing the content to convos you can now listen to on the go and in video. Host Emily Casey brings the founders, clinicians, investors, operators, and policymakers shaping the future of health into the room for candid, useful, and occasionally unruly conversations. This trailer offers a first taste of the questions the show will tackle. What happens when billions flow into biotech while policy struggles to keep up? How reliable are the latest AI health tools? What can at-home screening change for patients and the wider health system? And when everyone is talking about AI, where is the real advantage? What The Health goes beyond the headlines to work out what is real, what is hype, what is worth paying attention to and why it matters. Expect: candid conversations with leading minds in health innovationclear explanations without the health-speaksharp takes backed by factspractical context on the companies, ideas and policy shifts changing healthcarea smarter way to stay ahead without drowning in noise What The Health is more than a podcast. It is a newsletter, events platform and private community built for people who want to stay switched on to health and health tech. Subscribe to the newsletter and join the What The Health community: https://www.whatthehealth.io/ Follow the show: https://dayone.fm/show/what-the-health-with-emily-casey/ Brought to you by Tenmile. Tenmile partners with teams tackling major unmet needs in human health, helping turn bold ideas and breakthrough science into companies that can improve lives. Learn more: https://www.tenmile.com/ What The Health is part of the Day One Network and produced by W2D1 Media. This podcast is for general information and commentary and is not medical advice.

  3. Trailer

    Introducing What The Health with Emily Casey | Official Teaser

    Five years of health innovation coverage, millions of reads, and a community of 11,000+. Now finally, What the Health has a podcast too — bringing the content to convos you can now listen to on the go and in video. Host Emily Casey brings the founders, clinicians, investors, operators, and policymakers shaping the future of health into the room for candid, useful, and occasionally unruly conversations. This trailer offers a first taste of the questions the show will tackle. What happens when billions flow into biotech while policy struggles to keep up? How reliable are the latest AI health tools? What can at-home screening change for patients and the wider health system? And when everyone is talking about AI, where is the real advantage? What The Health goes beyond the headlines to work out what is real, what is hype, what is worth paying attention to and why it matters. Expect: candid conversations with leading minds in health innovationclear explanations without the health-speaksharp takes backed by factspractical context on the companies, ideas and policy shifts changing healthcarea smarter way to stay ahead without drowning in noise What The Health is more than a podcast. It is a newsletter, events platform and private community built for people who want to stay switched on to health and health tech. Subscribe to the newsletter and join the What The Health community: https://www.whatthehealth.io/ Follow the show: https://dayone.fm/show/what-the-health-with-emily-casey/ Brought to you by Tenmile. Tenmile partners with teams tackling major unmet needs in human health, helping turn bold ideas and breakthrough science into companies that can improve lives. Learn more: https://www.tenmile.com/ What The Health is part of the Day One Network and produced by W2D1 Media. This podcast is for general information and commentary and is not medical advice.

  4. 6d ago

    Are Your People More Productive or Just Faster? Claudia Barriga-Larriviere, Startup Flamingo

    Every great team she has ever seen shares one trait: they are comfortable with discomfort. Claudia Barriga-Larriviere has spent nearly 20 years building people and culture inside startups and global enterprises — and she thinks most of the AI conversation is quietly dodging the hard, human questions. In this episode of Building Tech Teams, James MacDonald sits down with Claudia Barriga-Larriviere — people-and-culture leader and founder of Startup Flamingo — for a practitioner-to-practitioner conversation on how capable people actually build teams. They get into self-awareness as a muscle rather than a gift, why Australia's love of harmony quietly kills direct feedback, and the difference between a team that is genuinely high-performing and one that is just stressed and running fast off a cliff together. Then it turns to AI — not as weather to brace for, but as a tool you have to point somewhere. Are your people more productive, or just faster? What do you lose when you automate the uncomfortable parts of the job — the feedback loop, the one-on-one, the human connection — and who is a flattened, agent-run org actually built for? Claudia makes the case that AI should augment an already good team, that you have to build that team first, and that the leaders winning this moment are the ones asking better questions instead of racing to be first. It's a conversation about discomfort, storytelling, balanced teams, and keeping the human in a human organisation. Chapters0:35 — The one trait every great team shares: comfortable with discomfort (plus self-awareness)1:46 — Is self-awareness born or built? Temperament, empathy and psychological safety3:28 — Why leaders dodge the hard conversation3:59 — Cutting her teeth on GFC redundancies: directness and an American education6:04 — Australia's harmony problem vs direct feedback6:43 — What "high performance" actually means (and what it doesn't)7:42 — The feedback loops we outsource because they're uncomfortable9:17 — Protect the plan, or chase the Nazis? An Indiana Jones lesson for leaders11:18 — Read fiction: storytelling, empathy and depersonalising feedback14:35 — Praise the person, critique the work — and when to call it out16:55 — Overconfident founders and the case for yin-and-yang teams18:39 — Powers of Two: debunking the lone genius (Lincoln, Lennon & McCartney, Jobs & Woz)23:13 — Hire for change, not to fit in24:20 — The maths of a founding team: builder, organiser, learner26:41 — Glue vs grease: does your team need cohesion or speed?28:53 — Project or person? The metabolism of a team29:47 — AI is a tool, not the weather33:16 — The narrative vs the technology — and the Tickle Me Elmo problem41:14 — Slow down to speed up: when the market rewards layoffs42:32 — The CPO's dilemma: more productive, or just faster?45:04 — When is the risk no longer worth it? (You're paying by the token)48:21 — Longevity isn't impact: off-ramps and the retention vanity metric49:52 — Is AI making the manager redundant?52:54 — The automatic ball thrower: what you lose when you automate connection58:31 — AI augments a great team — but you have to build that team first59:18 — Departing advice: play the tape to the end, and be in the business you're in1:03:32 — Purpose over "who gets there first" — go touch some grass About the GuestClaudia Barriga-Larriviere is a people-and-culture leader with nearly 20 years building teams across startups and global enterprises, and the founder of Startup Flamingo. LinksClaudia Barriga-Larriviere — Startup Flamingo: startupflamingo.comJames MacDonald — LinkedIn · NTP Talent (NewyTechPeople): ntptalent.com.au Hosted by James MacDonald, Managing Director of NTP Talent. Building Tech Teams is produced by Day One®, trusted partners in the technology space and the production partner behind Blackbird Ventures' Wild Hearts. Sister shows include First Cheque, Oversubscribed and In The Blink of AI. Episodes are cross-promoted across the network.

    Are Your People More Productive or Just Faster? Claudia Barriga-Larriviere, Startup Flamingo
  5. Jul 19

    What Makes a Founder Worth Backing at Pre-Seed? With Ilana Elbaz | GTM at Deel

    Episode SummaryIlana Elbaz was employee number five and the first go-to-market hire at Deel, helping scale the company from its early pivots through blockchain and payments to a business she helped grow from zero to hundreds of millions in ARR in just a few years. She's now an active angel investor and runs Deel's global pitch competition, which received tens of thousands of applications this year. In this episode, Cheryl and Maxine unpack how operating inside one of the fastest-scaling companies in the world shapes the way Ilana evaluates founders as an investor. She breaks down her "3-star model" for backing companies (right infrastructure, right team, right timing, read from right to left), why she looks for founders with velocity and speed over founders who claim to have it all figured out, and why the biggest red flag at pre-seed is a founder who narrows their market too early. You'll also hear why she pushes back on founders who insist on enterprise-only or single-market strategies before they even know their ICP, why treating international hiring as a growth problem rather than an HR problem is critical for founders building outside the US, and why Australian founders' instinct to think global from day one is a genuine advantage. Ilana shares what she learned scaling Deel's own go-to-market using the company's own product across dozens of countries, and why staying close to your first hundred customers matters more than shipping a polished product. She closes with her Big Cojones moment: repeatedly landing alone in unfamiliar countries, from opening entities in Thailand to sourcing product in China at 19, with no support system and straight into meetings with lawyers she'd never met. Time Stamps00:00 - Intro 04:15 – Ilana's first investment: buying Amazon stock at age 10 and the lesson she learned selling too early 09:30 – Why Ilana joined Deel as employee five, drawn in by the labor law and compliance nightmare of scaling internationally 14:05 – The 3-star model: right infrastructure, right team, right timing, and why it should be read backwards 17:50 – Why founders who claim to have it all figured out should be a pass 21:40 – The danger of narrowing your market too early at pre-seed 28:10 – Why treating global hiring as a growth problem, not an HR problem, changes everything 33:00 – What makes Australian founders well suited to thinking global from day one 36:45 – How to answer "what's your expansion plan" as a green flag for investors 40:20 – Inside Deel's global pitch competition: 35,000 applications and five investments 46:10 – Big Cojones moment: landing alone in unfamiliar countries to open new markets Mentioned in this episode: Pear Tree If you're a founder or operator trying to scale, here's the reality — Australian hiring is getting harder, salaries are at record highs, and the talent you need is increasingly out of reach. The best operators are quietly building offshore teams of engineers, marketers, accountants and analysts at a fraction of the cost. Pear Tree does it differently. We headhunt highly skilled talent from the Philippines and South Africa with full transparency on where every dollar goes, so your team is paid fairly and fully focused on your business. As a Day One listener, you’ll receive a free team audit to identify where offshore talent could move the needle in your business, plus 20% off your first hire. Deel x PX_Script 2 Deel x PX_Script 1 This podcast uses the following third-party services for analysis: Podtrac - https://analytics.podtrac.com/privacy-policy-gdrp Spotify Ad Analytics - https://www.spotify.com/us/legal/ad-analytics-privacy-policy/

    What Makes a Founder Worth Backing at Pre-Seed? With Ilana Elbaz | GTM at Deel

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