Dr. John Campbell

Campbellteaching

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

  1. Omicron science, promising news

    2h ago

    Omicron science, promising news

    New science explains South Africa's low rates of omicron severe disease SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron https://www.medrxiv.org/content/10.1101/2021.12.26.21268380v1 https://www.medrxiv.org/content/10.1101/2021.12.27.21268278v1 Institute of Infectious Disease and Molecular Medicine, University of Cape Town SARS-CoV-2 Omicron variant has multiple Spike (S) protein mutations These contribute to escape from the neutralizing antibody responses, reducing vaccine protection from infection We assessed the ability of T cells to react with Omicron spike In participants who were vaccinated with Ad26.CoV2.S (J and J) (n = 20) or BNT162b2 (Pfizer) (n = 15 or in unvaccinated convalescent COVID-19 patients (n = 15) SARS-CoV-2-specific T cells play a key role in modulating COVID-19 severity and provide protective immunity Results 70-80% of the CD4 and CD8 T cell response to spike was maintained across study groups The magnitude of Omicron cross-reactive T cells was similar to that of the Beta and Delta variants These results demonstrate that, despite Omicron’s extensive mutations and reduced susceptibility to neutralizing antibodies, the majority of T cell response, induced by vaccination or natural infection, cross- recognises the variant. Well-preserved T cell immunity to Omicron, is likely to contribute to protection from severe COVID-19, supporting early clinical observations from South Africa. Further explanation The limited effect of Omicron’s mutations on the T cell response suggests that vaccination or prior infection may still provide substantial protection from severe disease. Indeed, South Africa has reported a lower risk of hospitalisation and severe disease compared to the previous Delta wave Cross-reactive T cell responses acquired through vaccination or infection may contribute to these apparent milder outcomes for Omicron. The resilience of the T cell response demonstrated here also bodes well in the event that more highly mutated variants emerge in the future. Learn more about your ad choices. Visit megaphone.fm/adchoices

    17 min
  2. Covid vaccine and automobile accidents

    3h ago

    Covid vaccine and automobile accidents

    Are people vaccinated against covid more protected from road accidents .... or not. COVID Vaccine Hesitancy and Risk of a Traffic Crash https://www.amjmed.com/article/S0002-9343(22)00822-1/fulltext Background Coronavirus disease (COVID) vaccine hesitancy, is a reflection of psychology that might also contribute to traffic safety. So People that take covid vaccines are the sort of people who have less traffic accidents People who do not take covid vaccines are the sort of people who have more traffic accidents Methods Population-based longitudinal cohort analysis of adults Determined COVID vaccination status from electronic medical records Traffic crashes requiring emergency medical care Subsequently identified accidents from all (178) hospitals One month follow-up Results, (2021) N = 11,270,763 Total traffic accidents, 6,682 Unvaccinated, 16% Vaccinated, 84% Unvaccinated individuals 1,682 traffic crashes (25%) Equal to a 72% increased relative Confidence interval, (95%) 63% to 82% (P less than 0.001) What about Socioeconomic status Alcohol Sleep apnea Diabetes Depression Dementia Hypertension Cancer Covid infection Equal to a 48% increase after adjustment Confidence interval, (95%) 40% to 57% (P less than 0.001) The increased risks extended across the spectrum of crash severity Results similar for Pfizer, Moderna, or other vaccines Conclusions These data suggest that COVID vaccine hesitancy is associated with significant increased risks of a traffic crash. An awareness of these risks might help to encourage more COVID vaccination. Factors Distrust of government Belief in freedom Misconceptions of everyday risks Faith in natural protection Antipathy toward regulation Chronic poverty Exposure to misinformation Political identity Negative past experiences Limited health literacy Social networks, misgivings around public health guidelines Primary care physicians who wish to help patients avoid becoming traffic statistics, could take the opportunity to stress standard safety reminders such as wearing a seatbelt, obeying speed limits, and never driving drunk Paramedics, should be aware that unvaccinated patients are overrepresented in the aftermath of a traffic crash. Driver insurance policies in the future Together, the findings suggest that unvaccinated adults need to be careful indoors with other people and outside with surrounding traffic. https://www.youtube.com/watch?v=_iryCrHaozU&t=174s But Unvaccinated in Canada could not use, planes, trains, buses https://www.forbes.com/sites/sandramacgregor/2021/08/18/canada-to-make-proof-of-vaccination-mandatory-for-air-and-train-travel/?sh=6569fb1fd465 Also https://covid19-sciencetable.ca/wp-content/uploads/2021/04/Science-Brief_Vaccines-in-Essential-Workers_20210423_published2.pdf Vaccinated more likely to work remotely in Ontario in 2021 ‘Essential workers’ had lower vaccination rates (several pile ups in ice and bad weather) Over 65s do not commute So Staying at home reduces the chances of being in an accident Invalid title Patient in emergency department as a driver, passenger, or pedestrian (codes V00-V69) Total = 6,682 Drivers, 2,856 Passengers, 1,189 Pedestrians, 2,637 (Table 3 of the study) (Therefore, unvaccinated pedestrians more likely to be in an accidents that vaccinated pedestrians) People were considered unvaccinated for the first 14 days after vaccination Given the study only lasted a month, this is half of the time. So how many casualties were misclassified? If 602 of the 6,682 were misclassified, Any difference between the two groups would vanish (Igor Chudov) https://igorchudov.substack.com/p/the-unvaccinated-had-more-car-crashes Deaths at Scene Excluded 42 deaths at scene 8 deaths were included (550 people were actually admitted to hospital) Therefore 84% of death outcomes ignored Learn more about your ad choices. Visit megaphone.fm/adchoices

    12 min
  3. 3h ago

    Inconsistencies in official numbers

    Is UK government data accurate? Or is there under-reporting? https://coronavirus.data.gov.uk https://covid.joinzoe.com/data#levels-over-time https://www.youtube.com/watch?v=Hc7A1bVuSJU https://covid.joinzoe.com/post/worryingly-close-to-100-000-new-cases-a-day Poor lateral flow test reporting Less than 50% have government ‘classical symptoms’ Therefore, government under testing Loss of smell and taste, 6 Fever, 8 ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights Overall, coronavirus (COVID-19) infections continued to increase in England in the most recent week Percentage testing positive still highest in those in school years 7 to 11 Overall prevalence increases up to W/E 23rd October 2.02% in England (1 in 50 people) Week before, 1.79% (1 in 55 people) 2.56% in Wales (1 in 40 people) Week before, 2.31% (1 in 45 people) 1.31% in Northern Ireland (1 in 75 people) Week before, 0.76% (1 in 130 people) 1.36% in Scotland (1 in 75 people) Week before, 1.14% (1 in 90 people) Coronavirus antibodies remain high among UK adults (W/E 3rd October) https://blog.ons.gov.uk/2021/04/28/antibodies-and-immunity-how-do-they-relate-to-one-another/ 92.2% in England 90.0% in Wales 90.8% in Northern Ireland 91.3% in Scotland Positivity has increased in younger adults Showing signs of a slow decline in older adults Antibody finger prick tests A negative antibody test does not mean that a person is not protected Building up to 150,000 UK antibody tests per month Every month for the next year Coronavirus (COVID-19) deaths Between 13 March 2020 and 1 October 2021, 119,869 excess deaths above the five-year average Government figures https://coronavirus.data.gov.uk/details/deaths 140,392 163,515 Current UK deaths (ONS) 12,845 per week 14.8% above average Learn more about your ad choices. Visit megaphone.fm/adchoices

    29 min
  4. 3h ago

    Plausable mechanism for infertiliy after vaccines

    Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic https://journals.sagepub.com/doi/10.1177/09246479251353384 Vibeke and team, crowd funding, Me again - here is link to our crowdfunding - it would be great if you would link. https://buymeacoffee.com/batchdependency Observed Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics Limited data, relationship, COVID-19 vaccination status and birth rates. Objectives Nationwide data from the Czech Republic Rates of successful conceptions (SCs) (conceptions leading to live births 9 months later) For women who were either vaccinated or unvaccinated against COVID-19 before SC. Summary monthly COVID-19 vaccination and birth data Women in the Czech Republic aged 18–39 January 2021 to December 2023. Results 1,300,000 women aged 18–39 years in the Czech Republic Proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. SC rates for the vaccinated group were much lower than expected based on their proportion of the total population. Conclusions SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility. Learn more about your ad choices. Visit megaphone.fm/adchoices

    14 min
  5. Midazolam mortality

    4h ago

    Midazolam mortality

    Excess Deaths in the United Kingdom: Midazolam and Euthanasia in the COVID-19 Pandemic https://www.researchgate.net/publication/377266988_Excess_Deaths_in_the_United_Kingdom_Midazolam_and_Euthanasia_in_the_COVID-19_Pandemic Citation: Wilson Sy (2024) Excess Deaths in the United Kingdom: Midazolam and Euthanasia in the COVID-19 Pandemic. Medical & Clinical Research, 9(2), 01-21. Macro-data during the COVID-19 pandemic in the United Kingdom (UK) are shown to have significant data anomalies and inconsistencies with existing explanations. England 2020 UK spike in deaths, wrongly attributed to COVID-19 in April 2020, was not due to SARS-CoV-2 virus, which was largely absent, but was due to the widespread use of Midazolam injections, which were statistically very highly correlated (coefficient over 90 percent) with excess deaths in all regions of England during 2020. Importantly Excess deaths remained elevated following mass vaccination in 2021, but were statistically uncorrelated to COVID injections, while remaining significantly correlated to Midazolam injections. The widespread and persistent use of Midazolam in UK suggests a possible policy of systemic euthanasia. Unlike Australia, where assessing the statistical impact of COVID injections on excess deaths is relatively straightforward, UK excess deaths were closely associated with the use of Midazolam and other medical intervention. The UK iatrogenic pandemic Caused by euthanasia deaths from Midazolam and also, likely caused by COVID injections, https://www.researchgate.net/publication/374261986_Early_Indication_of_Long-Term_Impact_of_COVID_Injections but their relative impacts are difficult to measure from the data, due to causal proximity of euthanasia. Global investigations of COVID-19 epidemiology, based only on the relative impacts of COVID disease and vaccination, may be inaccurate, due to the neglect of significant confounding factors in some countries. Learn more about your ad choices. Visit megaphone.fm/adchoices

    18 min
  6. 8h ago

    Covid infections increasing again

    Zoe Health study report, Live time data https://health-study.joinzoe.com/ Incidence, = 152,071 (new symptomatic cases 0n 21st September) Current prevalence, 1,829,701 (people currently predicted to have symptomatic covid in the UK) R = 1.1 ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/infections W/E 5th September Professor Spector report https://www.youtube.com/watch?v=rQq91Z3ssqQ Daily new cases of symptomatic COVID Report and the data files download https://console.cloud.google.com/storage/browser/covid-public-data Average over the two weeks up to 20 September 2022. Daily new cases of symptomatic COVID UK = 148,830 Based on the number of newly symptomatic app users per day, and the proportion of these who give positive swab tests. Check against NHS data https://www.nhs.uk/conditions/coronavirus-covid-19/ https://coronavirus.data.gov.uk Past 7 days Testing positive, up 12.7% Admitted to hospital, 4,015 (up 16.9%) Deaths, 289, (down 24.3%) (within 28 days of a positive test) Deaths, List of covid (mostly BA.5) symptoms Sore throat, 68% Headache, 55% Cough, no phlegm 52% Blocked nose, 51% Runny nose, 51% Cough with phlegm, 47% Sneezing, 44% Hoarse, 43% Muscle pains / aches 31% Fatigue, 24% Dizzy, 21% Swollen neck glands, 19% Altered smell, 18% Sore eyes, 16% Shortness of breath, 15% Chest pain / tightness, 15% Chills or shivers, 14% Loss of smell, 13% Earache, 13% Fever, 12% Learn more about your ad choices. Visit megaphone.fm/adchoices

    20 min

About

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

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