Dr. John Campbell

Campbellteaching

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

  1. 25m ago

    BBC and vitamin D

    33% reduction in hospitalization with acute respiratory infections, (upper and lower) Covid Influenza Bronchitis Pneumonia Prostate cancer, colon cancer, ovarian cancer, breast cancer, cancer treatments, dementia, diabetes type 2, metabolic syndrome, obesity, polycystic ovary syndrome, all infections, covid, TB, low mood, Alzheimer’s Parkinson’s, MSK pains and problems, osteoporosis, MS, RA, SLE, DM1, Crohn’s, psoriasis, eczema, hypertension, CAD, heart failure, stroke, preeclampsia Vitamin D deficiency linked to hospital admissions https://www.bbc.com/news/articles/czx3g1d57xpo University of Surrey People with a severe vitamin D deficiency (below 15 nmol/L), a third more likely to be admitted to hospital with conditions including bronchitis and pneumonia. (15 nmol/L is 6 ng / ml) Abi Bournot, (lead author) "antibacterial and antiviral properties" of vitamin D are thought to help reduce the risk of respiratory tract infections." Improves immune recognition Supports T and B cell response Reduces excessive pro-inflammatory cytokines Promotes production of antimicrobial peptides against bacterial infections. Enhances antiviral white cell function, e.g. promotes interferon reserves "This research attaches hard data to support the theory. "Despite its importance to our overall health, many people are deficient and do not meet the government's recommended intake of 10 microgrammes of vitamin D per day." (10 micrograms is 400 iu) NHS data from 36,258 people. (40 to 69) For each 10 nmol/l (4 ng / ml) increase in vitamin D, the hospital admission rate for respiratory tract infections fell by 4%. Association between serum 25-hydroxyvitamin D status and respiratory tract infections requiring hospital admission: unmatched case-control analysis of ethnic groups from the United Kingdom Biobank cohort https://www.sciencedirect.com/science/article/abs/pii/S0002916525007713?via%3Dihub Background Vitamin D status has been found to be inversely associated with risk of respiratory tract infections (RTIs). Methods An unmatched case-control study (Observational, cases are not individually matched on specific characteristics) Data from United Kingdom Biobank Includes 500k adults with serum 25(OH)D status and hospital episodes N = 36,258, n = 27,872 Results 34% were White 28% Asian 19% Black 11% other 7% of mixed ethnicity. RTI rate was 8.5% (median time to RTI, 14.8 y) Each 25(OH)D +10 nmol/L increase) was significantly associated with a 4% lower hazard ratio (HR) for RTI hospitalization. (So difference between 15 nmol/L and 65 nmol/L would be 50% reduction) less than15 nmol/L v more than 75 nmol/L 33% reduction in hospitalization with acute respiratory infections Learn more about your ad choices. Visit megaphone.fm/adchoices

    BBC and vitamin D
  2. 25m ago

    Infrequent complications

    Changes of ECG parameters after BNT162b2 vaccine in the senior high school students https://pubmed.ncbi.nlm.nih.gov/36602621/ Full text link https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813456/ Data collected, December 2021 Published, January 2023 Aims Determine the ECG parameter change Determine efficacy of ECG screening after the second dose of BNT162b2 In cooperation with the school vaccination system of Taipei City government (Taiwan) N = 4,928 (mostly male) 12 to 18 year old Before and after 12 lead ECGs Three follow up 12 lead ECGs ECGs read by by pediatric cardiologists Serial comparisons of ECGs and questionnaire survey Heart rate increased significantly after the vaccine, (mean increase of 2.6 beats per minute) QRS duration and QT interval decreased significantly after the vaccine with increasing heart rate 763 (17.1%) had at least one cardiac symptom after the second vaccine dose. After the first dose, 209 (5.7%) had at least one cardiac symptom Cardiac symptoms Chest pain Palpitations Dizziness or syncope Depolarization and repolarization parameters All 4 cardiac symptoms significantly higher after the second dose of BNT162b2 vaccine (p less than 0.001) N = 4,928 Abnormal ECGs were obtained in 51 (1.0%) 31 students were asymptomatic ST – T changes, 37 Premature ventricular contractions, 4 Sinus bradycardia, 2 Atrial tachycardia, 1 Incomplete right bundle branch block, 3 Abnormal QRS, 2 Prolonged QT, 2 4 judged to have significant arrhythmia 1 was diagnosed with mild myocarditis 10, suspected pericarditis All of these symptoms improved over time Asymptomatic at one month No covid in Taiwan at this time. Conclusion Cardiac symptoms are common after the second dose of BNT162b2 vaccine Incidences of significant arrhythmias and myocarditis are 0.1% One in a thousand Rotavirus vaccine Rotashield, (1999) https://www.cdc.gov/vaccines/vpd-vac/rotavirus/vac-rotashield-historical.htm 1 to 2 serious events per 10,000 vaccinees (Intussusception) Vaccine withdrawn From the authors BNT162b2 has a better safety profile than mRNA-1273 Moderna Cardiac-related adverse effects, as peri- and myocarditis, are of particular concern because of possible serious complications US vaccina advice https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html#children https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html CDC recommends one updated (bivalent) booster dose: • For everyone aged 5 years and older if it has been at least 2 months since your last dose. • For children aged 6 months–4 years who completed the Moderna primary series and if it has been at least 2 months since their last dose. UK vaccine advice Who can get a COVID-19 vaccine Everyone aged 5 (on or before 31 August 2022) and over can get a 1st and 2nd dose of the COVID-19 vaccine. People aged 16 and over, and some children aged 12 to 15, can also get a booster dose. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Infrequent complications
  3. 2h ago

    Confirmed disturbing scandal

    Worst treatment sandal in HNS history (so far). Infected blood report https://www.infectedbloodinquiry.org.uk/reports https://www.infectedbloodinquiry.org.uk/reports/inquiry-report Rishi Sunak “a day of shame for the British state” “Today’s report shows a decades-long moral failure at the heart of our national life – from the National Health Service to the Civil Service, to ministers in successive governments, at every level the people and institutions in which we place our trust failed in the most harrowing and devastating way. “They failed the victims and their families and they failed this country.” “moral failure at the heart of our national life” in which doctors, civil servants and ministers had put reputations above patient safety. “On behalf of this and every government stretching back to the 1970s, I am truly sorry.” https://www.telegraph.co.uk/news/2024/05/20/infected-blood-scandal-inquiry-live-latest/ The final report concluded Health service and governments took part in a “chilling” cover-up, as they “closed ranks” to hide the truth, even destroying documents to keep patients in the dark. Sir Brian Langstaff the “horrifying” scandal could and should have been avoided, but a “catalogue of failures” led to “calamity”. https://www.telegraph.co.uk/news/2024/05/20/nhs-cover-up-avoidable-disaster-infected-blood-inquiry/ “It will be astonishing to anyone who reads this report that these events could have happened in the UK …that a level of suffering which it is difficult to comprehend, still less understand, has been caused to so many”. victims of the scandal “have been forced into a decades-long battle for the truth “Successive governments claimed that patients had received the best medical treatment available at the time, and that blood screening had been introduced at the earliest opportunity. Both claims were untrue. “Standing back, and viewing the response of the NHS and of government overall, the answer to the question ‘was there a cover-up?’ is that there has been. “Not in the sense of a handful of people plotting in an orchestrated conspiracy to mislead, but in a way that was more subtle, more pervasive and more chilling in its implications. “In this way there has been a hiding of much of the truth.” tragedy “was not an accident”. https://www.telegraph.co.uk/news/2024/05/20/infected-blood-inquiry-report-key-findings/ Learn more about your ad choices. Visit megaphone.fm/adchoices

    Confirmed disturbing scandal
  4. 2h ago

    Global deaths under-reported

    Under reporting of deaths, 19 months into the pandemic https://coronavirus.jhu.edu/map.html Total deaths, 5,018,949 Total cases, 247,883,004 Total vaccine doses, 7,129,732,439 World Health Organization https://www.who.int/data/stories/the-true-death-toll-of-covid-19-estimating-global-excess-mortality Based on the excess mortality estimates produced for 2020 we are likely facing a significant undercount of total deaths directly and indirectly attributed to COVID-19 Many countries still lack functioning civil registration and vital statistics systems Percentage of registered deaths https://www.who.int/data/data-collection-tools/score/dashboard#/ 98% in the European 10% in the African region Comparisons difficult Excess mortality The difference in the total number of deaths in a crisis, compared to those expected under normal conditions Therefore, includes direct and indirect impact WHO, 2020 data Official, 1,813,100 Lower bound, 3 million Region of the Americas in 2020 Excess mortality estimates range from 1.34 to 1.46 million 60% more than reported European Region in 2020 Excess mortality estimates range from 1.11 to 1.21 million 50% more than reported https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates Excess death calculations Actual worldwide toll, 16.8 million excess deaths 95% probability, 10.3 million to 19.5 million Official versus actual deaths (Economist) US, deaths = 745,274 US, deaths = 860,000 to 1 million China, deaths = 4,600 China, deaths = 150,000 to 1,700,000 India, deaths = 458,000 India, deaths = 1.2 million to 7.2 million Russia, deaths = 236,462 Russia, deaths = 870,000 to 910,000 Indonesia, deaths = 143,457 Indonesia, deaths = 300,000 to 1.2 million Pakistan, deaths = 28,477 Pakistan, deaths = 300,000 to 910,000 Bangladesh, deaths = 27,873 Bangladesh, deaths = 200,000 to 720,000 Turkey, deaths = 71,052 Turkey, deaths = 130,000 to 420,000 Mexico, deaths = 288,464 Mexico, deaths = 560,000 to 600,000 Brazil, deaths = 608,071 Brazil, deaths = 660,000 to 740,000 Factors Death tolls are heavily influenced by the age structure of a country’s population Rely on the assumption that officially published excess-mortality numbers are accurate Covid-19 disruption, some governments may have changed how they compile data Institute for Health Metrics and Evaluation, University of Washington https://covid19.healthdata.org/global?view=cumulative-deaths&tab=trend Total deaths are the estimated number of deaths attributable to COVID-19, including unreported deaths. Reported and unreported deaths, 11.9 million Learn more about your ad choices. Visit megaphone.fm/adchoices

  5. 3h ago

    44% of hospitalisations boosted

    CDC Says 44% of People Hospitalized With COVID Had Third Dose or Booster https://www.medscape.com/viewarticle/980351?src=mkm_ret_220912_mscpmrk_trdalrtuk03_int&uac=127834AR&impID=4631827&faf=1 Almost half the people who were hospitalized with COVID-19 last spring had been fully vaccinated and received a third dose or booster shot https://www.cdc.gov/mmwr/volumes/71/wr/mm7134a3.htm?s_cid=mm7134a3_x Laboratory-Confirmed COVID-19–Associated Hospitalizations Among Adults During SARS-CoV-2 Omicron BA.2 Variant Predominance Data from the COVID-19–Associated Hospitalization Surveillance Network March 20–May 31, 2022 Among hospitalized nonpregnant patients 39.1% had received a primary vaccination series and 1 booster (3 jabs) 5.0% had received a primary series and ≥2 boosters (4 jabs) 39.1 + 5 = 44.1% (Medscape is correct, well under by 0.1%) Therefore, CDC advises All adults should stay up to date† with COVID-19 vaccination, multiple nonpharmaceutical and medical prevention measures should be used to protect those at high risk for severe COVID-19 illness, irrespective of vaccination status Why? Unvaccinated adults were 3.4 times more likely to be hospitalized with COVID than those who were vaccinated Also in this CDC report Hospitalization rates among adults aged ≥65 years, increased threefold Hospitalization rates in adults aged 18–49 and 50–64 years, both increased 1.7-fold during omicron surge https://support.google.com/youtube/answer/11161123 Vaccine safety: content alleging that vaccines cause chronic side effects, outside of rare side effects that are recognised by health authorities Efficacy of vaccines: content claiming that vaccines do not reduce transmission or contraction of disease https://support.google.com/youtube/answer/9891785 Claims that there is a guaranteed prevention method for COVID-19 Claims that any medication or vaccination is a guaranteed prevention method for COVID-19 Claims about COVID-19 vaccinations that contradict expert consensus from local health authorities or the WHO Claims that an approved COVID-19 vaccine will cause death, infertility, miscarriage, autism or contraction of other infectious diseases Claims that COVID-19 vaccines do not reduce risk of serious illness or death New Zealand drops mask and vaccine mandates in sweeping Covid changes https://www.theguardian.com/world/2022/sep/12/new-zealand-drops-mask-and-vaccine-mandates-in-sweeping-covid-changes Deaths, 1,950 (about 50 at the end of 2021) Hospitalisations, (NZ key metric) down sharply in recent weeks Jacinda Ardern Today marks a milestone in our response. Finally, rather than feeling that Covid dictates what happens to us, our lives, and our futures, we take back control Mask-wearing, only compulsory in healthcare settings (largely ignored anyway) End of vaccine mandates, for workers and inbound travellers Tests on arrival in NZ, encouraged Covid-positives, still required to isolate (no longer household contacts) This will be the first summer in three years where there won’t be the question of what we will and what won’t be cancelled because of Covid cases Learn more about your ad choices. Visit megaphone.fm/adchoices

  6. 3h ago

    Stroke and death subsequent to Moderna

    Fatal Post COVID mRNA-Vaccine Associated Cerebral Ischemia https://pubmed.ncbi.nlm.nih.gov/37064937/ Keywords: COVID-19; Moderna vaccine; cerebral edema; neurology; stroke. McMillan N, Rosenberg HJ, Anderson MP, Pal P, Stephenson K, Fehnel CR. Fatal Post COVID mRNA-Vaccine Associated Cerebral Ischemia. Neurohospitalist. 2023 Apr;13(2):156-158. doi: 10.1177/19418744221136898. Epub 2022 Dec 5. PMID: 37064937; PMCID: PMC10091442. Department of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA. Background Venous thromboses have been linked to several COVID-19 vaccines Here we describe a case of post-Moderna COVID-19 vaccination arterial infarct, with vaccine-associated diffuse cortical edema, that was complicated by refractory intracranial hypertension. Case summary 24 hrs after receiving her first dose of the Moderna COVID-19 vaccine, a 30-year-old female developed severe headache. Three weeks later she was admitted with subacute headache and confusion. Imaging initially showed scattered cortical thrombosis with an elevated opening pressure on lumbar puncture. An external ventricular drain was placed, but she continued to have elevated intracranial pressure. Ultimately, she required a hemicraniectomy, but intractable cerebral edema resulted in her death. Pathology was consistent with thrombosis and associated inflammatory response. Conclusion Though correlational, her medical team surmised that the mRNA vaccine may have contributed to this presentation. The side effects of COVID-19 infection and vaccination are still incompletely understood. Though complications are rare, clinicians should be aware of presentations like this one. More information Had prior asymptomatic COVID-19 infection three months earlier 24-hours after first dose of the mRNA COVID-19 vaccine (Moderna). Developed severe, atypical throbbing bi-frontal headache Headaches were atypical (no prior headaches) Three weeks after vaccination Developed blurred vision and confusion Bifrontal headache with photophobia Lumbar puncture revealed lymphocytosis Broad spectrum antimicrobial coverage was started. Her mental status acutely worsened later that evening New left hemiparesis. Elevated D-dimer CSF cultures and PCR testing returned negative Intracranial pressure remained refractory to maximal medical management, including deep sedation, paralysis and hypothermia, prompting a right decompressive hemicraniectomy. The patient expired from refractory cerebral edema. Brain autopsy showed infiltrates of CD8 and CD4-positive T-cells, in association with intravascular thrombi Fungal and bacterial stains were negative. Discussion Diffuse endothelial damage and vessel wall inflammation, suggested an underlying pro-thrombotic state and T cell inflammatory response. The arterial infarct in this case is likely related to a pro-thrombotic state Due to the large volume of infarction, the patient was not started on anticoagulation after extensive discussion of the risks vs potential benefit. In summary, administration of COVID-19 vaccine was considered a possible cause of the extensive multifocal arterial thromboses with associated inflammatory response and elevated intracranial pressure given the temporal association. The mechanism for initial elevation in intracranial pressure is not known but may relate to cerebral autoregulatory changes in the setting of cortical microvascular thrombosis. https://petermcculloughmd.substack.com/p/fatal-post-covid-19-mrna-vaccine?utm_source=post-email-title&publication_id=1119676&post_id=144566381&utm_campaign=email-post-title&isFreemail=false&r=1f3dql&triedRedirect=true&utm_medium=email Suspected Unexpected Serious Adverse Reaction (SUSAR) such as this would have put a pause on the entire study and an investigation into why this happened and Learn more about your ad choices. Visit megaphone.fm/adchoices

    Stroke and death subsequent to Moderna

About

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

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