FLASCO OncoPod

Florida Society of Clinical Oncology

The FLASCO OncoPod is a podcast series that brings you engaging interviews and conversations with oncology champions and thought leaders. Each episode explores important topics in cancer care, from the latest clinical advancements to FLASCO events and initiatives. Whether it’s discussing groundbreaking research, policy updates, or sharing personal stories from members, the OncoPod keeps oncology professionals informed and connected. It’s your go-to source for staying up-to-date on FLASCO’s efforts to support and strengthen the oncology community across Florida.

  1. 1d ago

    The Evolving Management of Hepatocellular Carcinoma: Prevention, Multidisciplinary Care, and Emerging Therapies

    Hepatocellular carcinoma (HCC) continues to present unique challenges for oncology teams, requiring coordinated multidisciplinary care and an evolving understanding of both liver disease and cancer management. In this episode of the FLASCO OncoPod, Dr. Beau Bosko Toskich, MD, FSIR, Professor of Radiology, Medical Oncology, and Radiation Oncology and Director of Interventional Oncology at Mayo Clinic Comprehensive Cancer Center, provides a comprehensive overview of the modern HCC treatment landscape. Dr. Toskich discusses the changing epidemiology of hepatocellular carcinoma, emphasizing the growing impact of metabolic-associated liver disease, the importance of early detection and surveillance, and opportunities for disease prevention. He explores how multidisciplinary collaboration—including hepatology, surgery, interventional radiology, medical oncology, and radiation oncology—has transformed patient care, while highlighting the expanding role of locoregional therapies, immunotherapy, transplant evaluation, and emerging combination treatment strategies. Listeners will gain practical insights into patient selection, downstaging approaches, and the latest advances that are reshaping outcomes for patients with HCC. Whether you routinely manage liver cancer or simply want to stay current on one of oncology's fastest-evolving disease states, this episode offers valuable clinical perspectives on delivering personalized, multidisciplinary care for patients with hepatocellular carcinoma.

    The Evolving Management of Hepatocellular Carcinoma: Prevention, Multidisciplinary Care, and Emerging Therapies
  2. Jul 20

    Part 4, Advancing Biomarker-Driven Care Through Optimized IHC Testing: Practical Insights on IHC Testing Across Tumor Types

    In this episode of the FLASCO OncoPod, host Dr. Edgardo Santos, President of the Florida Society of Clinical Oncology (FLASCO), leads a multidisciplinary discussion on the evolving role of immunohistochemistry (IHC) in precision oncology. Joined by Dr. Lamees Saeed (Tampa General Hospital Cancer Institute), Dr. Jesus Fabregas (Memorial Cancer Institute), Dr. Ana Sandoval (Herbert Wertheim Cancer Institute at Baptist Health South Florida), and Dr. Nathalie McKenzie (AdventHealth Cancer Institute), the panel explores how IHC has evolved from a diagnostic tool into a critical component of biomarker-driven treatment selection. In part 4, the panel examines the real-world barriers that continue to affect IHC testing, including variability in reflex testing, pathology workflows, tissue stewardship, and reporting consistency. Experts share practical strategies for improving communication between oncologists and pathologists, streamlining testing protocols, and ensuring patients receive timely, comprehensive biomarker evaluation. Looking ahead, the discussion explores how artificial intelligence, digital pathology, electronic medical record integration, and automated clinical trial matching may transform precision oncology while reinforcing that multidisciplinary collaboration remains essential to delivering high-quality, personalized cancer care. The episode concludes with key takeaways clinicians can implement to strengthen biomarker-driven decision-making in their own practices. This podcast is being sponsored by Daiichi Sankyo.

    Part 4, Advancing Biomarker-Driven Care Through Optimized IHC Testing: Practical Insights on IHC Testing Across Tumor Types
  3. Jul 16

    Part 3, Advancing Biomarker-Driven Care Through Optimized IHC Testing: Practical Insights on IHC Testing Across Tumor Types

    In this episode of the FLASCO OncoPod, host Dr. Edgardo Santos, President of the Florida Society of Clinical Oncology (FLASCO), leads a multidisciplinary discussion on the evolving role of immunohistochemistry (IHC) in precision oncology. Joined by Dr. Lamees Saeed (Tampa General Hospital Cancer Institute), Dr. Jesus Fabregas (Memorial Cancer Institute), Dr. Ana Sandoval (Herbert Wertheim Cancer Institute at Baptist Health South Florida), and Dr. Nathalie McKenzie (AdventHealth Cancer Institute), the panel explores how IHC has evolved from a diagnostic tool into a critical component of biomarker-driven treatment selection. The panel discusses how expanding biomarker indications are changing when and how testing is performed, from first-line diagnosis through disease progression. Experts explore the growing clinical importance of HER2-low and HER2-ultralow expression in breast cancer, the role of comprehensive biomarker testing in gynecologic malignancies, and how IHC and next-generation sequencing work together to guide personalized treatment strategies in thoracic oncology. The conversation also highlights the importance of standardized pathology reporting, multidisciplinary collaboration, and balancing timely treatment with the need for complete biomarker results to ensure patients receive the most appropriate targeted therapies. This podcast is being sponsored by Daiichi Sankyo.

    Part 3, Advancing Biomarker-Driven Care Through Optimized IHC Testing:  Practical Insights on IHC Testing Across Tumor Types
  4. Jul 16

    Part 2, Advancing Biomarker-Driven Care Through Optimized IHC Testing: Practical Insights on IHC Testing Across Tumor Types

    In this episode of the FLASCO OncoPod, host Dr. Edgardo Santos, President of the Florida Society of Clinical Oncology (FLASCO), leads a multidisciplinary discussion on the evolving role of immunohistochemistry (IHC) in precision oncology. Joined by Dr. Lamees Saeed (Tampa General Hospital Cancer Institute), Dr. Jesus Fabregas (Memorial Cancer Institute), Dr. Ana Sandoval (Herbert Wertheim Cancer Institute at Baptist Health South Florida), and Dr. Nathalie McKenzie (AdventHealth Cancer Institute), the panel explores how IHC has evolved from a diagnostic tool into a critical component of biomarker-driven treatment selection. In part 2, the panel explores why routine biomarker testing is becoming an essential part of cancer care, highlighting how markers such as mismatch repair (MMR), HER2, PD-L1, and Claudin 18.2 are helping clinicians personalize treatment strategies and improve patient outcomes. Through real-world clinical examples, the discussion examines the value of reflex testing, when repeat testing may be appropriate, and how close collaboration between oncologists, pathologists, and multidisciplinary care teams helps ensure patients receive timely, biomarker-driven treatment. The conversation also addresses practical workflow considerations, including pathology communication, turnaround times, and strategies for integrating evolving testing standards into everyday clinical practice. This podcast is being sponsored by Daiichi Sankyo.

    Part 2, Advancing Biomarker-Driven Care Through Optimized IHC Testing: Practical Insights on IHC Testing Across Tumor Types
  5. Jun 5

    CLL Treatment Evolution: Rethinking Monotherapy vs Combination Strategies in the Era of Next-Generation BTK Inhibitors

    The treatment landscape for chronic lymphocytic leukemia (CLL) has transformed dramatically over the past decade, creating new opportunities and new questions for clinicians managing this increasingly complex disease. In this episode of the FLASCO OncoPod, FLASCO President Edgardo Santos, MD, FACP, FASCO, sits down with renowned CLL expert Javier Pinilla-Ibarz, MD, PhD, of Moffitt Cancer Center to discuss how advances in targeted therapies are reshaping treatment decisions across the CLL continuum. Together, they explore the evolution of CLL care from chemoimmunotherapy to modern treatment approaches centered around BTK inhibitors, BCL2 inhibitors, and anti-CD20 monoclonal antibodies. The conversation examines how molecular and genetic risk factors, including IGHV mutation status, TP53 abnormalities, and cytogenetic findings, influence first-line treatment selection and long-term management strategies. Dr. Pinilla-Ibarz shares practical insights into the ongoing debate between fixed-duration combination regimens and continuous therapy approaches, highlighting the benefits, limitations, and patient-specific considerations that guide real-world clinical decision-making. The discussion also covers measurable residual disease (MRD), emerging MRD-guided treatment strategies, management of high-risk disease, sequencing therapies after relapse, and the growing role of next-generation BTK inhibitors. Looking ahead, the episode explores promising therapies on the horizon, including novel BTK degraders, next-generation BCL2 inhibitors, cellular therapies, and other innovative approaches that may further improve outcomes for patients living with CLL. Whether you are a hematologist, oncologist, advanced practice provider, or healthcare professional interested in the latest developments in blood cancers, this episode offers a comprehensive and clinically relevant update on where CLL treatment stands today and where the field is headed next.

    CLL Treatment Evolution: Rethinking Monotherapy vs Combination Strategies in the Era of Next-Generation BTK Inhibitors

Ratings & Reviews

5
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About

The FLASCO OncoPod is a podcast series that brings you engaging interviews and conversations with oncology champions and thought leaders. Each episode explores important topics in cancer care, from the latest clinical advancements to FLASCO events and initiatives. Whether it’s discussing groundbreaking research, policy updates, or sharing personal stories from members, the OncoPod keeps oncology professionals informed and connected. It’s your go-to source for staying up-to-date on FLASCO’s efforts to support and strengthen the oncology community across Florida.