28 episodes

Flux is a podcast about the pioneers building companies at the frontier of technology. This series of interviews goes beyond the soundbites, allowing some of the most interesting players in technology to share their insider expertise and explain the challenges they face in building the future. Hosted by Alice Lloyd George.

Flux Alice Lloyd George

    • Technology
    • 5.0, 57 Ratings

Flux is a podcast about the pioneers building companies at the frontier of technology. This series of interviews goes beyond the soundbites, allowing some of the most interesting players in technology to share their insider expertise and explain the challenges they face in building the future. Hosted by Alice Lloyd George.

    27: Alex Bisignano — Decoding Pandemic Genetics

    27: Alex Bisignano — Decoding Pandemic Genetics

    Hi from Alice and the Flux team. We hope you are safe and well. 
    In the latest episode I talk with Alex Bisignano, founder of Phosphorus is the second ever company to be approved by the FDA for at-home saliva testing to detect COVID-19. Alex has been on the frontlines of the pandemic in New York City. While most companies are using synthetic data, Alex and his team have collected live samples from patients in the lab.
    Phosphorus has been able to rapidly develop virus and antibody test products, even though that wasn't the company's prior business. Alex shares how he thinks about supply chain reliability and how they are ramping up test manufacturing. We also get into genetics as a possible predictor for COVID-19 severity, which biological pathways may play a role, and what it would look like if we had large-scale biobanks.
    If we are able to correctly identify who is at higher risk, what are the implications for employment and privacy policy? We get into the ethical questions around mandatory testing and disclosure and how countries like China have responded to the pandemic. Alex also reveals how he thinks Silicon Valley may shift in its attitude towards the hard sciences and biotech.
    Full transcript on Medium. This episode was produced by Daniel Bouza.

    • 24 min
    26: Andy Coravos — A Brave New World of Digital Medicine

    26: Andy Coravos — A Brave New World of Digital Medicine

    Welcome back to Flux! In this episode I talk with Andy Coravos the co-founder of Elektra Labs, which is building a future of digital medicine that's data-driven and secure. Recently we’ve seen an explosion of wearables and sensors in healthcare. How accurate are these monitoring tools? How secure are they from hackers? Elektra is cataloguing these distributed devices and has created benchmarks for pharmaceutical companies, doctors and device makers. We're also now seeing the advent of digital therapeutics such as video games that help treat ADHD or PTSD. Is the FDA equipped to respond to these changes? How will doctors and pharmacies prescribe digital medicine? 
     
    Andy shares her thoughts on the FDA and what she feels is the balance between proper regulation and advancing progress. She discusses what wearables she personally is comfortable using and why a Hippocratic Oath for devices is important. Andy tells me about her family of tinkerers and inventors, why she finds meditation critical, and how she got the courage to jump from private equity to startups. 
     
    Full transcript on Medium. This episode was produced by Daniel Bouza.

    • 37 min
    25: LaTurbo Avedon — the Avatar That Grew up in Cyberspace

    25: LaTurbo Avedon — the Avatar That Grew up in Cyberspace

    In this episode we try out a new format. I talk remotely with LaTurbo Avedon, an online avatar who has been active as an artist and curator since 2008. Her responses have been run through a speech synthesizer.
     
    Recently we've seen a wave of next-gen virtual stars rise up, from Lil Miquela in the west to pop-stars like Kizuna AI in the east. As real-time avatar representation becomes more accessible, what emergent behaviors will we see and what will our virtual relationships look like? LaTurbo was early to exploring these questions of identity and experimenting with telepresence. She has shape-shifted across media types, spending time in everything from AOL and chat rooms, to MMOs, virtual worlds and social media platforms. She shares her thoughts on how social networks have breached our trust, why a breakup is likely, and how users should take control of their data. We get into the rise of battle royale gaming, why multiplicity of self is important, and how we can better express agency and identity online.
    This episode was produced by Adriene Lilly. Full transcript with links on Medium.

    • 25 min
    24: Matt Cauble—Soylent’s Co-Founder Goes After Alcohol 

    24: Matt Cauble—Soylent’s Co-Founder Goes After Alcohol 

    In this episode I talk with Matt Cauble the co-founder of Kin Euphorics, a functional beverage company that aims to reduce stress — “all bliss, no booze.” Matt was previously a co-founder of Soylent and he shares tales from the company’s early days, describing how they made one of the largest pivots in YC history from building software-defined radios to meal-replacement shakes. He explains why Soylent resonated and we get into co-founder Rob Rhinehart's latest interest in space settlement and the Mars industry event he hosted in the Mojave. Matt shares why he is now interested in wellness, how he's applying lessons from Soylent to building the Kin community, and why strong companies often look like new social movements. We get into the product’s formula, which includes nootropics and adaptogens, and what it means to challenge a ritual as ancient as alcohol.

    • 37 min
    23: Eric Marcotulli—Bottling the Fountain of Youth

    23: Eric Marcotulli—Bottling the Fountain of Youth

    Eric Marcotulli is the co-founder of Elysium, a life sciences company developing consumer-facing health products based on aging research. Elysium's first product is Basis, a supplement that increases NAD levels and activates sirtuins, boosting cellular health and longevity. 
     
    In the latest episode of Flux we discuss why longevity companies like Sirtris Pharmaceuticals failed, which was initially bought for $720 million in 2008. Eric explains why going direct to consumer is the best strategy and what the current Basis user base looks like. He shares what its like working with eight nobel laureates on his science advisory board and how they decide what product research to pursue. He gets into the importance of bringing peer review rigor to the category, how he plans to build consumer trust, why cellular senescence is a particular area of interest, what his personal health routine is and how he thinks about the singularity. 

    • 41 min
    22: Isaac Cohen —An XR Trailblazer on how to Build Humane Technology

    22: Isaac Cohen —An XR Trailblazer on how to Build Humane Technology

    In the this episode I sit down with Isaac Cohen (Cabbibo), a fascinating creator at the forefront of VR and AR who has released a number of apps and experiences that push the boundaries - you can find some of his pieces on Steam. He has a background in physics and interface design, previously worked at Leap Motion, and has been an artist in residence at Unity and Adobe. Isaac shares his views on why realism in VR is the wrong approach and how developers need to approach it in a transformative rather than a derivative way. He describes the ARkit workflow, how he thinks about using AR to give users agency, and why emotional efficiency is important in computing. He gets into some of the UX insights he's picked up along the way, which creators inspire his work, what today's corporates can learn from the long-term research done at places like Xerox PARC, and the role artists play in pointing them towards the right questions.
    Full transcript on Medium.
     
    This episode was produced by Adriene Lilly and Allison Behringer. 

    • 42 min

Customer Reviews

5.0 out of 5
57 Ratings

57 Ratings

magellan12345 ,

love it

amazing guests and good banter

DougJF ,

love it

amazing guests and thoughtful topics. please do more episodes

crazyfoosf ,

Superb hostess, amazing guests

The woman who hosts this does an amazing job of building rapport with her guests quickly, which allows her to seamlessly transition between questions and witty commentary... textbook repartee. Really great content, and there’s just something about her British accent...

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