The Brain Podcast

Joanne Bell
  • 3,7 (3)
  • CIÊNCIAS DA VIDA
  • DUAS VEZES/SEMANA

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists

  1. 25 DE SET.

    Investigating autoimmune mechanisms underlying progressive supranuclear palsy

    Welcome to the 30th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with senior author Professor Gabor G Kovacs of the Brain article entitled: Midbrain cytotoxic T cells as a distinct neuropathological feature of progressive supranuclear palsy Listen to the fascinating insights exploring the autoimmune side of progressive supranuclear palsy (PSP) following identification of cytotoxic T cells within the mid-brain of PSP post-mortem tissue. The pattern of T cells appears to follow both temporal progression of underlying PSP and may also relate to rate of disease progression. Professor Kovacs discusses potential autoimmune treatment in a neurodegenerative disorder, such as PSP, and others. Check out the full article on the Brain website as part of the August 2025 issue: https://doi.org/10.1093/brain/awaf135 This episode was co-hosted, edited and produced by David Michael and Adam Handel, co-produced by Xin You Tai and Antonia Johnston, original music by Ammar Al-Chalabi.

    26min

  2. 20 DE AGO.

    Can transcriptional analysis detect efficient remyelination in multiple sclerosis?

    Welcome to the 29th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with first author of the Brain article entitled: Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis We are joined by Alida Chen for an interesting discussion into detecting transcriptional changes that may identify efficient remyelination in multiple sclerosis. Using brain bank donor tissue, the authors examine donors who show efficient remyelination compared with those who had poorly remyelinating lesions. They discuss interesting findings around the epithelial–mesenchymal transition pathway as well as the MTORC1 signalling pathway. Further, the team discusses how these findings may translate to in vivo understanding of efficient remyelination in patients with MS as well as other experimental models that may help elucidate this.   Check out the full article on the Brain website as part of the June 2025 issue: https://doi.org/10.1093/brain/awae414 This episode was co-hosted, edited and produced by Chaitra Sathyaprakash and Andreas Thermistocleous, edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    21min

  3. 25 DE JUN.

    Nephrology Meets Neurology: how kidney health links to neurodegeneration

    Welcome to the 28th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with three authors of the Brain article entitled: The relationship between kidney health and neurodegenerative diseases Ms Melody Zuo, Dr Le Chang and Professor Sarah A Gagliano Taliun grace the Brain podcast with an insightful discussion into their recent review examining the connection between kidney disease and neurogeneration. They describe the critical microvascular connection as well as the role of uraemia and small molecules like erythropoetin. Additonally, methodological issues around survival bias, the use of mendelian randomisation and the importance of metadata in the growing age of large available datasets.  Check out the full article on the Brain website and will be part of the August 2025 issue: https://doi.org/10.1093/brain/awaf113 This episode was co-hosted, edited and produced by Chaitra Sathyaprakash and Andreas Thermistocleous, edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    37min

  4. 14 DE MAI.

    Understanding traumatic brain injury with high dimensional proteomic analysis

    Welcome to the 27th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with first author Dr Lucia M Li of the Brain article entitled: High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury Listen to the fascinating insights into classifying traumatic brain injury (TBI) using high dimensional proteomic analysis. TBI may start with a head injury but evidence suggests that multiple different underlying pathophysiological pathways can emerge thereafter. Dr Li also describes how she envisages the future of TBI assessment and potential management. Check out the full article on the Brain website as part of the March 2025 issue: https://doi.org/10.1093/brain/awae305 This episode was co-hosted, edited and produced by David Michael and Adam Handel, co-produced by Xin You Tai and Antonia Johnston, original music by Ammar Al-Chalabi.

    25min

  5. 16 DE ABR.

    Glymphatic homeostasis in heart failure- more in but not out?

    Welcome to the 26th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with first author Dr Marios Kritsilis and senior author Associate Professor Iben Lundgaard of the Brain article entitled: Loss of glymphatic homeostasis in heart failure This academic duo from Lund University discuss their fascinating findings exploring glymphatic homeostasis in a mouse model of heart failure. Counter-intuitively, there may be more influx but not efflux associated with reduced ejection fraction. This has interesting implications on heart failure associated cognitive changes and risk of developing dementia.  Check out the full article on the Brain website as part of the March 2025 issue: https://doi.org/10.1093/brain/awae411 This episode was co-hosted, edited and produced by Xin You Tai and Roberto Bellanti, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    33min

  6. 27 DE FEV.

    Adult congenital myasthenic syndromes - discussing the diagnostic dilemma and other findings from a longitudinal cohort

    Welcome to the 25th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with senior author Dr Tanya Stojkovic of the Brain article entitled: Congenital myasthenic syndromes in adults: clinical features, diagnosis and long-term prognosis Dr Stojkovic discusses findings from an impressive longitudinal adult cohort of congenital myasthenia syndrome and important issues around accurate diagnosis of congenital myasthenic syndromes and use of electromyography and muscle biopsy. Check out the full article on the Brain website as part of the November 2024 issue: https://doi.org/10.1093/brain/awae124 This episode was co-hosted by David Michael and Roberto Bellanti,  edited and produced by Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    22min

  7. 22 DE JAN.

    Nociceptors are functionally male or female: from mouse to monkey to man?

    Welcome to the first episode of 2025 for The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  This episode features a discussion with senior author Dr Frank Porreca of the Brain article entitled: Nociceptors are functionally male or female: from mouse to monkey to man? Dr Porreca discusses important findings into the  sexual dimorphic nature of nociception and how it could and indeed should affect clinical trial participant design, precision medicine and need for more sex specific studies to unravel the regulation of pain nociception in male and female individuals. Check out the full article on the Brain website as part of the December 2024 issue: https://doi.org/10.1093/brain/awae179 This episode was co-hosted by Chaitra Sathyaprakash and Andreas Thermistocleous,  edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    38min

  8. 11/12/2024

    Academic neurology in the UK: a plea to turn away from the precipice

    Welcome to the 23nd episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications.  In this episode, we bring on authors Dr Helen Devine and Professor Simon Mead to discuss their opinion article entitled: Academic neurology in the UK: a plea to turn away from the precipice. The discussions covers the growing concerns regarding the future of academic neurology in the UK and potential solutions. They discuss the parallels seen around the world as this is a growing global problem. They end with their thoughts on why academic neurology is still extremely rewarding and exactly what they would do if they started again. Check out the full article on the Brain website as part of the July 2024 issue: https://doi.org/10.1093/brain/awae151 This episode was co-hosted by Andreas Thermistocleous and Adam Handel,  edited and produced by Andreas Thermistocleous and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.

    29min
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Classificações e avaliações

3,7
de 5
3 avaliações

Sobre

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists

Informações

  • Criado por
    Joanne Bell
  • Anos de atividade
    2022 - 2025
  • Episódios
    30
  • Classificação
    Livre
  • Copyright
    © 2022
  • Site do podcast
    The Brain Podcast

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