High Intensity Health with Mike Mutzel, MS Author Mike Mutzel interviews Jeff Bland, Datis Kharrazian, Ben Greenfield, Abel James, Dave Asprey, Ben Lynch, Jade Teta and Corey chuler

Early onset cancers are on the rise in young adults, yet experts claim they 'don't know what's driving the surge.' Research finds Millennials have more chronic health conditions compared to other generations, likely from early introduction of processed foods.
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----------------------Show Notes--------------------------
00:00 Intro
06:94: early onset cancers in young
30:00 Rise in Cancers
1:15 Global increase
2:23 Metabolic health and cancer
3:00 Berberine and food cravings
3:50 Cancer no longer a disease of the elderly
4:15 Warburg Effect
5:11 High glucose is linked with cancer
6:35 Mainstream medicine food suggestions
7:20 Poor metabolic health and cancer
8:11 Otto Warburg
9:47 High A1C and Cancer
10:39 Glucose intake and mortality 
11:15 Carbohydrate intake and cancer
12:00 Conclusions

Let's take a deep dive into protein, how much you need for your bodyweight, muscle gain, fat loss and why aging increases protein requirements.
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Link to Studies: https://bit.ly/3PmKE7r

-----------Show Notes----------------------
00:00 Intro
0:17 Protein Deep Dive
0:22 Protein thresholds
1:04 Protein, muscle and weight loss
1:32 Strength and mortality 
2:23 RDA for protein is low
3:32 Protein targets for healthy people
4:39 Pre-exercise protein
5:27 Creatine 
6:43 Protein intake for all ages
7:27 Important table to consider 
8:02 Over 65 need more protein 
8:45 Protein timing for muscle gain 
10:00 Protein around exercise 
10:12 Pulse VS even distribution 
12:21 Protein pulse as you get older 
13:29 Pre-bed protein 
15:29 Protein and diabetes
16:17 How much protein you need

A new study finds vegan dieters have higher concentrations of omega-6 fatty acids and lower quantities of health-promoting omega-3 fatty acids, including pro-resolving lipid mediators, in their cell membranes when compared to omnivores.
Resolvins are bioactive lipids made from dietary omega-3 fatty acids that help resolve inflammation.
Resolvins were not detected in the plasma of any vegan subjects, whereas nine out of twenty-four omnivores had detectable concentrations.
These new findings have important implications for heart, brain and prenatal health.

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Link to Studies: https://bit.ly/3sMkdAu

----------------Show Notes--------------------
00:00 Intro
0:17 Vegan VS Omnivore health-promoting omega-3 fatty acids
0:36 Omega-3 Index
0:50 HRV in Vegan VS Omnivore
1:32 Main takeaway
2:10 Linoleic acid decreases conversion of Omega-3
3:42 Importance of your omega-3 index
4:10 HRV in vegans VS Omnivores
5:10 Omega-3 Index and HRV
6:04 Seed oils lower conversion of ALA to EPA and DHA
6:31 Main findings
7:30 ALA conversion is low
8:02 Creatine is low in vegan dieters
9:57 LISTEN TO THIS!

The health benefits of ‘weight loss’ are cancelled out if the weight that you’re losing is from muscle. Here's why you should prioritize protein and resistance training to lose body fat instead. 
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Studies Mentioned:

Christoffersen, B. Ø. et al. Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss. Obesity 30, 841–857 (2022).
Time Stamps:
0:20 Weight Regain due to muscle loss
0:45 Prioritize muscle health with fat loss
1:47 Stimulants have side-effects
2:24 GLP-1 agonists aren’t great
3:23 Metabolic Adaptations with dieting
4:00 Brown fat activation
4:55 Lean tissue loss
6:10 Aerobic VS Resistance Training
6:23 Preventing muscle loss
7:27 This image explains all
8:15 Preventing fat gain
9:50 Brown fat activation
11:59 Consistency is key with brown fat activation
12:45 Cold plunges and heart health
 

After years of intensive LDL-lowering therapies heart disease is still the leading cause of death, claiming over 600,000 lives annually in the USA alone. It's time to focus more on triglycerides and metabolic health. 
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Here’s a few key takeaways: 

01:45 LDL lowering drugs do not affect triglycerides. 
03:41 Triglycerides and remnant cholesterol are associated with the formation of plaque in vessels throughout your body. 
05:45 Total cholesterol minus HDL minus LDL helps you determine your remnant cholesterol. 
11:20 Triglyceride rich lipoproteins promote inflammation and adhesion. 
12:00 High triglycerides (fasted and non-fasted) are associated with higher risk of atherosclerotic cardiovascular disease.
14:40 Increased triglyceride concentration is associated with a 37% increased risk of cardiovascular disease.

New research shows exercise is one of the most important tools for fighting off respiratory infections, including COVID-19. Here's a summary of the most recent data...
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Studies, Video and Images: https://bit.ly/3KRY2z2
 
1. Torres, G., Constantinou, D., Gradidge, P., Patel, D. & Patricios, J. Exercise is the Most Important Medicine for COVID-19. Curr. Sports Med. Rep. 22, 284–289 (2023).
 
2. Jimeno-Almazán, A. et al. Effects of a concurrent training, respiratory muscle exercise, and self-management recommendations on recovery from post-COVID-19 conditions: the RECOVE trial. J. Appl. Physiol. 134, 95–104 (2023).

Time Stamps:
00:00 Exercise is the most important medicine for COVID19.
02:10 Exercise reduces the severity of upper respiratory tract infections.
02:30 Exercise reduces odds of contracting COVID, being hospitalized, being in the ICU, and risk of death.
05:10 Exercise reduces inflammation.
07:30 Autophagy and mitophagy occur with every exercise session, optimizing energy production.
09:20 Exercise prevents the accumulation of exhausted T cells.
10:45 Exercise releases myokines that help the thymus gland release T cells.
11:00 T cells and B cells are mobilized in the blood by increased catecholamines during exercise, and likely cold exposure.
11:20 Natural killer cells and viral specific T cells occur with each exercise session.
12:00 Aerobic exercise mobilizes T lymphocytes, T cells, and effector cells.
13:00 Exercise exerts anti-inflammatory effects within the heart.
13:50 Stem cells from muscle are released during intense exercise.
14:35 Your frontline mucosal defense is impacted by exercise.
15:30 Myokines from exercise increase BDNF.