High Intensity Health with Mike Mutzel, MS Author Mike Mutzel interviews Jeff Bland, Datis Kharrazian, Ben Greenfield, Abel James, Dave Asprey, Ben Lynch, Jade Teta and Corey chuler

A new study finds over 40% of cancer deaths in the US are preventable through lifestyle changes such as reducing smoking, alcohol consumption, and obesity, while promoting exercise and a healthy diet, with a specific focus on the protective benefits of exercise for women against breast cancer.
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Research Mentioned:
 
Islami, F. et al. Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States, 2019. CA: A Cancer J. Clin. (2024) doi:10.3322/caac.21858.

Key Takeaways:
CNN Article Overview (00:53):
Specific Risk Factors (01:46):
Cancer Prevention Strategies (02:48):
Role of Exercise (04:25):
2019 Study Findings (06:15):
Alcohol Consumption Impact (10:07):
Diet and Cancer Risk (10:59):
Conclusion (11:53):
 

For the past 60 years the medical community has obsessively focused on lowering LDL-cholesterol levels…
Research shows these five preventable health conditions make LDL-Cholesterol more likely to cause artery plaque build-up, even if your LDL-Cholesterol levels are low.
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Research Mentioned:
Zanoni, P., Velagapudi, S., Yalcinkaya, M., Rohrer, L. & Eckardstein, A. von. Endocytosis of lipoproteins. Atherosclerosis 275, 273–295 (2018).

Ference, B. A., Braunwald, E. & Catapano, A. L. The LDL cumulative exposure hypothesis: evidence and practical applications. Nat. Rev. Cardiol. 1–16 (2024) doi:10.1038/s41569-024-01039-5.
Time Stamps:
00:45 LDL's link with atherosclerosis is nuanced.

 02:30 Initial damage to the arterial wall makes LDL levels problematic.

03:45 Increases risk of arterial wall damage: elevated blood pressure, insulin resistance/diabetes, smoking/vaping, obesity, elevated blood viscosity, consuming oxidizableoils.

08:40 High LDL and high triglycerides suggest insulin resistance and increased cardiovascular risk.

09:50 Start with diet and exercise together.

11:20 Statins have concerning side effects.

13:15 Plaque formation begins early in life.

13:50 High LDL is found in centenarians.

14:44 Centenarians are metabolically healthy.

15:40 Your liver makes LDL cholesterol.

16:10 Every cell in your body requires cholesterol.

18:00  Diets high in seed oils make your LDL more likely to be oxidized.

20:55 30-50% of people who have heart attacks have optimal serum cholesterol.

New research suggests vitamin D and A work better when they're taken together. Here's more food for thought...
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Link to study: https://medicinskiglasnik.ba/article/36
------------Show Notes-------------------------
0:00 Intro
0:20 Vitamin D receptor binding requires vitamin A. 
0:50 Retinol is found in animal-based products. Pre-vitamin A is from vegetables.
1:40 Pairing vitamin A and vitamin D supports immune system, brain, and blood sugar health.
2:40 Excessive supplemental vitamin A in pregnant women can affect fetal growth.  
4:25 There are fewer micronutrients in your food.
5:45 Paired vitamin D and vitamin A balance the anti-inflammatory mechanisms of the immune system.
7:25 Mike suggests that you supplement with a retinol, not a beta carotenoid version of pre-vitamin A.

Mark Bell and Nsima Inyang delve into the transformative benefits of sunlight and outdoor activity for enhancing hormone levels, accelerating fat loss, and improving overall health.
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Link to Video Interview: https://youtu.be/mX3Mt5glQKY
Time Stamps

0:00 Intro
2:30 Exercise snacks
4:30 Cardio helps you get shredded 
5:30 Movement between sets
7:30 Exercise capacity 
8:22 Fat loss and diet
10:40 How Nsima stays shredded 
12:17 Cycling Carbs
13:26 Calories VS Carbs
15:45 Protein for muscle gain 
18:00 How much protein do you need
19:41 Red meat VS Fish VS Chicken
25:00 Cheat meals
27:00 the power of being outside

A recent study has revealed the presence of microplastics in the male penis, linking these particles to erectile dysfunction.
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--------------Show Notes----------------------------
0:00 Intro
0:05 microplastic particles make their way to the male penis
0:49 study detected microplastic particles
1:46 microplastic particles in the carotid artery plaque
2:12 microplastics and erectile dysfunction
3:55 Study Title 
4:11 Top prevention tips
4:58 face masks and microplastics 
6:18 small plastics still absorbed 
6:37 Key ways to avoid
 

Dr. Zinkov discusses ways to use peptides therapeutically to improve tissue rejuvenation and repair, promote longevity, enhance muscle growth, and boost mood, vitality, and libido. She discusses the benefits and risks, sourcing, dosages, cycling, administration routes, and how they work in combination w/ hormone optimization.
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Link to Video, Show Notes and Research: https://bit.ly/4bcEks6
Show Notes:
02:45 Peptides stimulate your endogenous production of growth hormone.
03:10 Sermorelin does not increase growth hormone beyond super physiologic levels.
04:35 Peptides can improve hormone health, longevity, reverse aging-related processes of inflammation and injury recovery.
08:45 Growth hormone improves cell function.
11:05 Sermorelin stimulates growth hormone secretion for about 12 minutes.
12:30 Growth hormone peaks are nighttime and post-workout.
14:30 Symptoms of suboptimal growth hormone.
15:45 IGF-1 is a biproduct of growth hormone breakdown.
18:30 Additional strategies.
22:05 Poor diet and lifestyle choices reduce growth hormone.
25:10 Women in their teens and 20s may have suboptimal production of hormones.
30:30 Progesterone receptors can be stimulated with herbal treatments.
31:30 Xenoestrogens cause more disruptive receptor stimulation.
33:15 Obesity is one of the biggest risk factors for breast cancer.
34:30 Growth hormone stimulates collagen production.
37:15 Low dose Rapamycin slows the aging process.
40:30 Methylene Blue has been used as a nootropic.
43:55 Nicotine directly and quickly stimulates the vagal nerve.
53:00 Growth hormone does not cause cancer.