The Human Upgrade with Dave Asprey

Dave Asprey
The Human Upgrade with Dave Asprey

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human. Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward. Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

  1. Ayurveda Meets Biohacking: 5000-Year-Old Medicine Secrets for Modern Stress | Mona Sharma

    1D AGO

    Ayurveda Meets Biohacking: 5000-Year-Old Medicine Secrets for Modern Stress | Mona Sharma

    This episode reveals the ancient health protocols Western medicine forgot, and how they are now being used to heal stress, rewire the nervous system, and radically improve human performance.  Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR  Host Dave Asprey sits down with Mona Sharma, a renowned Ayurvedic practitioner, celebrity wellness expert, and functional medicine advocate who grew up in a Canadian ashram. Mona combines ancient Vedic practices with cutting-edge science to help her clients, including Will Smith and other high-profile figures, achieve high performance, emotional resilience, and deep-rooted healing. She translates the 5,000-year-old system of Ayurveda into practical strategies anyone can use to optimize health in today’s chaotic world.  Together, they explore how Ayurvedic biohacking techniques like breathwork, circadian alignment, detoxification, and herbal medicine are now being validated by data in neuroscience, mitochondrial biology, and functional medicine. They also dive into trauma, stress rewiring, nervous system resilience, and how to build your own modern “ashram” for healing and longevity.  You’ll learn how to shift from hypervigilance into calm, how to optimize vagal tone, and how ancient practices like tongue scraping and ghee detox intersect with modern tools like cold therapy, nootropics, sleep optimization, and self-quantification.  If you care about biohacking, neurohacking, longevity, or want to understand how emotional states shape mitochondrial function, this episode is packed with grounded insight and powerful takeaways. It offers a masterclass in approaching health through both spiritual and systems biology perspectives, while avoiding burnout and noise.  You’ll also hear how Mona:  • Reversed her own heart condition after failed surgeries and medication  • Guides high-stress clients using Ayurvedic principles and modern lab testing  • Connects vagal nerve stimulation, breathwork, and emotional detox for lasting nervous system regulation  • Uses personalized nutrition, pulse reading, and lifestyle upgrades to treat the root cause  • Brings ancient healing into modern wellness spaces like Upgrade Labs  This is essential listening for anyone exploring Smarter Not Harder protocols, blending functional medicine with high-level biohacking, and finding sustainable ways to enhance vitality without relying on pharmaceuticals or performance fads.  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares and brings you real tools to become more resilient, aware, and high performing.    SPONSORS:  -Calroy | Head to https://calroy.com/dave for an exclusive discount.   -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Mona’s Website –  https://www.monasharma.com/  • Mona’s Instagram: https://www.instagram.com/monasharma/?hl=en  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  • 00:00 Trailer  • 00:54 Intro  • 01:44 Mona’s Personal Healing Journey  • 03:42 What Ayurveda Really Is  • 07:15 Breathwork and Daily Rituals  • 09:41 Where Western Medicine Falls Short  • 13:27 Ancient Tools That Still Work  • 22:02 Nervous System as the Healing Key  • 31:50 Rewiring Through Visualization  • 32:59 Transformations with Celebrity Clients  • 33:31 Stress in the Public Eye  • 34:18 Finding Core Values and Alignment  • 35:48 Home Detox, Real Impact  • 37:52 Blending Body and Spirit  • 48:52 Understanding Your Dosha  • 54:02 Applying Ayurveda Today  • 58:34 Final Thoughts and Takeaways  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    59 min
  2. The Biohacker’s Guide to CIA Mind Control & Brainwashing

    3D AGO

    The Biohacker’s Guide to CIA Mind Control & Brainwashing

    You’re being programmed, and it’s more subtle and pervasive than you think. From invisible influence to psychological manipulation, this episode shows you how to recognize when your thoughts aren’t really yours.  Host Dave Asprey uncovers the hidden science of mind control with Harvard historian Rebecca Lemov. She is a professor of the History of Science at Harvard University and one of the world’s leading experts on psychological manipulation, surveillance science, government experimentation, and Cold War brainwashing programs. Her groundbreaking research into MK Ultra, behavioral psychology, and reeducation campaigns reveals exactly how external forces hijack your thoughts, emotions, and decisions, without you knowing.  They break down how mind control evolved from CIA-funded brain implants and LSD experiments into today’s algorithmic persuasion, trauma-based manipulation, and tech-driven influence. This episode gives you practical tools to defend your thoughts, upgrade your awareness, and reclaim your mental sovereignty.  This is essential listening for anyone serious about biohacking, mindfulness, longevity, mental performance, self-awareness, hacking the nervous system, emotional control, and high-performance mindset training.  You’ll Learn:  • How the CIA used MK Ultra, psychedelics, hypnosis, and implants to test behavior control  • What mind control looks like in modern media, social platforms, and persuasive technology  • How unresolved trauma and emotional blind spots leave you vulnerable to manipulation  • The connection between neurohacking, mindset, and mental autonomy  • How to recognize when you are running someone else’s code  • The best psychological tools to build resilience and conscious awareness  • How to build a “mental firewall” with meditation, breathwork, and attention training  Watch this episode on YouTube for the full video experience:  https://www.youtube.com/@DaveAspreyBPR  Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living.  Episodes are released every Tuesday and Thursday, where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing.  SPONSORS:  -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  -OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY.  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Rebecca’s New Book – The Instability of Truth: https://wwnorton.com/books/9781324075264  • Rebecca's Website: https://rebeccalemov.com/ • Rebecca’s Instagram: https://www.instagram.com/rebeccalemov/?hl=en  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  • 00:00 Trailer  • 01:01 Intro  • 01:49 Mind Control at Harvard  • 02:54 Hypnosis and Mental Programming  • 04:48 Morning Routines and Meditation  • 06:02 AI Companions and Digital Influence  • 11:17 MK Ultra and Government Experiments  • 20:25 Archives and the War on Truth  • 24:49 Marketing and Manipulation  • 27:22 Chilling CIA Mind Control Stories  • 33:59 Meditation and God Encounters  • 34:40 Biohacking Origins  • 35:15 Building Mental Resilience  • 36:11 Compassion as Control  • 37:54 Escaping Modern Programming  • 39:57 Free Will vs. Influence  • 46:03 Therapy and Suggestion  • 49:25 SEER Training and Torture Simulation  • 01:03:27 One-Pointed Focus  • 01:06:46 Final Reflections  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 4m
  3. Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo

    MAY 16

    Military Tech Goes Public: Think 30% Faster with This Brain Hack | Geoffrey Woo

    Your brain runs slow when it’s running on the wrong fuel.  In this episode of The Human Upgrade, Dave Asprey sits down with Geoffrey Woo, Stanford-trained computer scientist and founder of Ketone-IQ, to reveal the high-performance brain fuel once reserved for Special Forces and elite athletes.  Discover how ketones helped operators in combat zones sharpen focus, recover faster, and boost reaction speed by up to 30%. Learn why glucose falls short, how to hack your mitochondria for better cognition, and what it takes to unlock rapid-fire thinking on demand.  This is brain energy for people who want to win, at life, work, and everything in between. Whether you’re fasting, flying, or facing real pressure, ketones flip the switch.  You’ll Learn:  • Why ketones beat glucose for focus, speed, and mental clarity  • How Special Forces use ketones to recover brain function under stress  • The truth about esters, salts, and the new wave of ketone diols  • How ketones support faster thinking, emotional control, and clean energy  • What makes Ketone-IQ different, and how Dave stacks it for peak performance  • The best ways to combine ketones with fasting, workouts, and meditation  • Why your metabolism controls your mood, reaction time, and resilience  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Ketone-IQ Website –  https://ketone.com/pages/dave-asprey?utm_source=partners&utm_medium=referral&utm_campaign=DAVE  • Geoffrey's Website: https://www.geoffreywoo.com/  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  • 00:00 – Trailer  • 02:00 – Intro  • 02:12 – Ketosis & brain performance  • 02:53 – Geoffrey’s background  • 03:52 – Ketone supplement evolution  • 04:41 – What makes Ketone-IQ different  • 07:18 – Manufacturing breakthroughs  • 13:53 – Entrepreneur mindset  • 18:58 – Future of biohacking  • 45:59 – Why classics still matter  • 46:23 – Cultural decline  • 47:04 – Decentralization  • 48:25 – Info overload & mental clarity  • 49:38 – Ketones & consciousness  • 57:49 – Religion & belief systems  • 01:03:32 – Key biohacking biomarkers  • 01:12:47 – Brain data & future upgrades  • 01:26:34 – Listener offer  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 27m
  4. The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners

    MAY 15

    The Anti-Aging Chamber That Rewinds Your Biological Clock|Dr. Jason Sonners

    Your cells are starving. Not for food—but for oxygen.  In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Jason Sonners, world-renowned hyperbaric expert and regenerative medicine pioneer, to reveal how controlled oxygen under pressure is becoming one of the most powerful tools in anti-aging and performance science.  You’ll learn how hyperbaric oxygen therapy (HBOT) triggers stem cell activation, rewires your epigenome, boosts mitochondrial energy, and reverses biological aging—if you use it the right way. Jason shares breakthrough findings from his latest PhD research comparing low- and high-pressure chambers, with surprising results on inflammation, telomeres, cognitive performance, and recovery speed.  This is next-gen longevity—measurable, stackable, and customizable. From sleep upgrades and HRV boosts to stacking HBOT with fasting, methylene blue, or red light, this episode dives into what it takes to oxygenate your biology at the deepest level.  You’ll Learn:  • How hyperbaric oxygen therapy (HBOT) triggers stem cell regeneration and cellular repair  • Why mild-pressure chambers may be more powerful than you think • What HBOT does to inflammation, brain fog, and biological aging markers  • How to stack HBOT with fasting, red light, and methylene blue for amplified results  • What Dr. Sonners’ PhD research reveals about oxygen pressure and genetic expression  • The truth about oxygen toxicity—and how to avoid the common mistakes  • How elite performers use HBOT for brain optimization, recovery, and resilience  ** Get 30% of yourr tickets to the Biohacking conference by going to https://biohackingconference.com/2025 and use code ‘OXYHEALTH’ **  Thank you to our sponsors!   -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.   -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Jason's Website –  www.hbotusa.com  • OxyHealth Website: https://www.oxyhealth.com/  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com   Timestamps:  • 00:00 Trailer  • 01:59 Intro  • 03:14 New research on aging and oxygen  • 05:39 Mild vs. hard-shell chambers  • 13:05 HBOT for longevity and stem cells  • 16:43 How to optimize your sessions  • 22:35 Best therapies to stack with HBOT  • 25:40 Oxygen delivery and safety  • 26:43 Altitude and chamber effects  • 30:01 Key benefits of hyperbaric therapy  • 34:22 Supplement synergy and timing  • 37:25 Pressure and oxygenation findings  • 39:27 Medical vs. welding oxygen  • 44:57 Safety myths and toxicity risks  • 47:39 Future of biohacking with oxygen  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    49 min
  5. The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon

    MAY 13

    The New Science Behind Psychedelics, Exotic Shrooms, & Daily Flow-States | Matt Zemon

    Your brain has a gear you’ve never touched. Psychedelics can shift you into it.  In this episode of The Human Upgrade, Dave Asprey uncovers how high-performance psychedelic mushrooms help you access flow states, rewire your brain, and enhance clarity, energy, and emotional resilience. This is next-level biohacking rooted in real science.  You will learn how to use psychedelics with intention. When to microdose. When to go deep. How to stack them with nootropics for even stronger results. Dave breaks down the latest research on psilocybin, brain plasticity, trauma release, and how to turn ancient compounds into modern performance tools.  What You Will Learn in This Episode:  • How psychedelic shrooms unlock flow, focus, and creative power  • Why psilocybin boosts neuroplasticity, mood, and emotional healing  • Microdosing vs. full-dose: what works, when, and how  • How to stack psychedelics with nootropics and other biohacks  • The newest research on brain optimization and long-term benefits  • How to use psychedelics safely, strategically, and for real results  • Why shrooms may be the strongest mental upgrade in your toolkit  Thank you to our sponsors!   -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.   -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.   Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Matt’s Website –  https://mattzemon.com/  • Matt's Instagram - https://www.instagram.com/matt.zemon/  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  • 00:00 – Trailer  • 01:00 – Intro  • 06:01 – Personal Psychedelic Journeys  • 07:39 – Psychedelics and Self-Discovery  • 11:59 – Safe Use and Smart Navigation  • 29:09 – Psychedelics and Society  • 36:40 – Building Trust in the Process  • 37:14 – Facing Inner Fear  • 37:38 – Choice and Healing  • 37:51 – Diet and Conscious Decisions  • 38:55 – Judgment and Relationships  • 39:29 – Spirituality and Psychedelics  • 40:07 – The Entheogenic Reformation  • 41:29 – Past Lives and Expanded States  • 43:44 – Where Science Meets Spirituality  • 49:59 – Gratitude and Compassion in Healing  • 01:01:47 – The Power of Apologies  • 01:04:56 – Psychedelics in Therapy  • 01:08:57 – Final Thoughts on Psychedelics and Culture  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 11m
  6. Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah

    MAY 9

    Why Oral Testosterone Is the Ultimate Upgrade for Energy, Mood and Longevity (Men AND Women) | Shalin Shah

    Low testosterone is sabotaging your health, motivation, and longevity. Diet alone will not fix it.  In this episode of The Human Upgrade, Dave Asprey sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to expose the truth about testosterone decline in both men and women. They break down why testosterone is crashing worldwide, why natural fixes almost always fail, and how the latest science finally makes testosterone therapy safer, simpler, and more effective than ever before.  You will discover why testosterone is essential for dopamine, brain function, sleep, muscle, libido, and mitochondrial health. Fixing your levels can reverse fatigue, brain fog, poor motivation, and slow aging itself.  Shalin reveals how new oral testosterone technology (Kyzatrex®) overcomes the dangers of old therapies and restores natural hormone rhythms without needles, creams, or dangerous side effects.  What You Will Learn in This Episode:  • Why testosterone matters for men and women at every age  • The real causes of the global testosterone crash  • Why diet, sleep, and exercise cannot fully fix low testosterone  • How testosterone drives dopamine, motivation, and longevity  • The breakthrough that makes oral testosterone safe and effective  • How Kyzatrex® lowers SHBG and boosts free testosterone naturally  • Why maintaining youthful testosterone levels protects brain, muscle, libido, and lifespan  • How to safely use testosterone therapy without suppressing fertility or causing side effects  ** Visit livethrive.co/asprey to get a discount on your first month's supply! **  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Purchase Kyzatrex® – https://livethrive.co/?utm_campaign=11813552-Asprey • Shalin’s Instagram - https://www.instagram.com/themetabolicceo/  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  00:00 Trailer  00:52 Introduction  01:29 Global Decline in Testosterone Levels  02:27 Symptoms of Low Testosterone  03:48 Personal Journey with Testosterone Therapy  05:06 The Role of Testosterone in Overall Health  06:18 Testosterone Levels in Men and Women  08:48 Challenges and Innovations in Testosterone Delivery  16:25 The Importance of Circadian Rhythm in Testosterone Therapy  19:19 The Future of Testosterone Therapy  32:00 Investment and Development in Testosterone Therapy  34:57 Introduction to FDA and Hormone Replacement  35:31 FDA’s Impact on Women’s Health  36:10 Testosterone and Cardiovascular Risk  39:05 Testosterone and Depression  40:30 Testosterone Testing and Misconceptions  44:58 The Testosterone Project and Female Hormone Therapy  47:51 Testosterone’s Role in Longevity and Health  55:37 Cost and Accessibility of Testosterone Therapy  01:04:03 Conclusion and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 5m
  7. The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD

    MAY 8

    The Deadliest Room in Your House — And How to Detox It for Better Health | Aly Cohen MD

    Your environment is rewiring your hormones, fertility, and long-term health without your consent.  In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Aly Cohen, board-certified rheumatologist, integrative medicine specialist, and environmental health educator. Together they expose how common toxins in plastics, pesticides, drinking water, personal care products, and food packaging are hijacking your biology.  Dr. Cohen explains how daily chemical exposures contribute to autoimmune disease, thyroid dysfunction, hormone imbalance, infertility, obesity, cancer, and accelerated aging. You will learn how to identify hidden endocrine disruptors, spot surprising sources of microplastics and PFAS (“forever chemicals”), and apply science-backed detox strategies to protect your hormones, fertility, metabolism, and longevity.  What You’ll Learn in This Episode:  • How chemicals in household, cleaning, and beauty products disrupt hormones  • The link between environmental toxins, autoimmune disease, thyroid issues, and infertility  • Hidden sources of microplastics and PFAS chemicals and how to eliminate them  • Affordable, practical steps to detox your home, water, and personal care routine  • Dr. Cohen’s top biohacks to protect fertility, balance hormones, and build toxin resilience    THANK YOU TO OUR SPONSORS!  -BON CHARGE | Go to https://boncharge.com and use code DAVE for 15% off.   -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Aly’s Website –  https://thesmarthuman.com/  • Aly's Website - https://alycohenmd.com/  • Aly’s New Book – Detoxify: https://alycohenmd.com/books  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  00:00 Trailer  02:01 Introduction  02:15 Rheumatism and Rheumatology  03:36 Autoimmune Diseases and Toxins  04:17 Chemical Impact on Health  04:49 Personal Health Journey  06:15 Microplastics and Immune Disruption  08:21 Resilience and Lifestyle Changes  21:45 Nutritional Deficiencies  26:48 Lab Results and Assessments  34:40 Detoxification and Resilience  41:14 Personal Journey Continued  42:22 Clean Drinking Water  44:20 Travel Hacks for Water  46:15 Hotel Room Detox Tips  50:06 EPA Water Standards  53:06 Restaurant Toxins and Home Safety  55:36 Top Toxic Household Items  01:08:31 Synthetic Materials Impact  01:13:30 Final Thoughts and Book  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 13m
  8. Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh

    MAY 6

    Biohacking Your Heart Health: The Life-Saving Molecule You NEED to Know | Dr. Anurag Singh

    What if you could reverse the age of your heart...without leaving home?  In this episode of The Human Upgrade, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer of Timeline, to reveal groundbreaking science that targets cardiovascular aging at the cellular level. You’ll discover how mitochondrial decline drives heart failure, why postmenopausal women face skyrocketing cardiac risks, and how one powerful molecule, Urolithin A, can rejuvenate your heart’s energy systems.  Dr. Singh shares clinical research showing how Urolithin A improves mitochondrial function, boosts endurance, and may even reverse biological aging markers in the heart. You’ll also learn how simple lifestyle biohacks, combined with cellular nutrition, can protect your cardiovascular health and extend your healthspan.  What You’ll Learn in This Episode:  • The link between mitochondrial decline and heart failure  • Why women’s cardiac risk skyrockets after menopause  • How Urolithin A stimulates mitophagy and energy renewal  • New human clinical data on reversing cardiac aging markers  • Biohacking strategies to fortify your cardiovascular health  • How to optimize endurance, recovery, and heart resilience   THANK YOU TO OUR SPONSORS!  -STEMREGEN | Head to https://www.stemregen.co/dave for 20% off your first order.   -Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.    Resources:   • Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/  • Timeline Website –  https://www.timeline.com/partners/dave-asprey  • Timeline Instagram - https://www.instagram.com/timeline_longevity/  • 2025 Biohacking Conference: https://biohackingconference.com/2025  • Danger Coffee: https://dangercoffee.com  • Dave Asprey’s Website: https://daveasprey.com  • Dave Asprey’s Linktree: https://linktr.ee/daveasprey  • Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com  • Own an Upgrade Labs: https://ownanupgradelabs.com  • Upgrade Labs: https://upgradelabs.com  • 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com  Timestamps:  • 00:00 — Trailer  • 02:11 — Supplements that help  • 03:05 — Long-term benefits  • 04:38 — Stacking with lifestyle  • 22:19 — Heart health connection  • 29:39 — Mitochondria & brain function  • 33:04 — Glymphatic system & Alzheimer’s  • 33:53 — Bed height & brain health  • 34:18 — Why mitochondria matter  • 35:43 — Inflammation & dysfunction  • 38:12 — Transplants & consciousness  • 39:19 — Meditation’s effects  • 40:33 — The ultimate biohacking stack  • 43:06 — Creatine for sleep & focus  • 50:00 — Fertility insights  • 57:23 — Skin health  • 01:00:28 — Final thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    1h 4m
See All (1.3K)

Hosts & Guests

4.6
out of 5
6,856 Ratings

About

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™. You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human. Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward. Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

Information

More From Integrity Network

You Might Also Like

To listen to explicit episodes, sign in.

Stay up to date with this show

Sign in or sign up to follow shows, save episodes, and get the latest updates.
Select a country or region

Africa, Middle East, and India

Asia Pacific

Europe

Latin America and the Caribbean

The United States and Canada