High Signal: Data Science | Career | AI

Delphina

Welcome to High Signal, the podcast for data science, AI, and machine learning professionals. High Signal brings you the best from the best in data science, machine learning, and AI. Hosted by Hugo Bowne-Anderson and produced by Delphina, each episode features deep conversations with leading experts, such as Michael Jordan (UC Berkeley), Andrew Gelman (Columbia) and Chiara Farranato (HBS). Join us for practical insights from the best to help you advance your career and make an impact in these rapidly evolving fields. More on our website: https://high-signal.delphina.ai/

  1. Jun 18

    Episode 41: The Verification Crisis: Why Trust Is the New Bottleneck in AI

    Noah Smith, economist and author of Noahpinion, joins High Signal to look at what AI is already changing… and what it isn’t. The conversation moves beyond the usual productivity hype to ask harder questions: Is agentic coding actually increasing revenue per hour worked? Will software remain a high-margin business if AI makes it easy to clone? And what happens when generating content, code, vendors, applications, and companies becomes much cheaper than verifying them? Noah argues that one of the biggest near-term shifts is not simply automation, but trust. AI is beginning to replace parts of the internet’s knowledge infrastructure — search, Stack Overflow, Reddit, and how-to content — while also flooding markets with new forms of slop. For AI builders and leaders, the central challenge may become less about producing more and more about knowing what is real, valuable, and worth trusting…. In a word, verification. LINKS Noah Smith on X Noahpinion — Noah's newsletter Noah's writing we discuss: You Are What You Consume by Noah Smith How Much More Software Do We Really Need? by Noah Smith What If a Few AI Companies End Up With All the Money and Power? by Noah Smith My Thoughts on AI Safety by Noah Smith Updated Thoughts on AI Risk by Noah Smith Salarymen, Specialists, and Small Businesses by Noah Smith Books, essays, and reports mentioned: Status and Culture by W. David Marx (Viking, 2022) If Anyone Builds It, Everyone Dies by Eliezer Yudkowsky and Nate Soares (2025) Machines of Loving Grace by Dario Amodei (2024) All Watched Over by Machines of Loving Grace by Richard Brautigan (poem, 1967) The Bitter Lesson by Rich Sutton (2019) Forecasting the Economic Effects of AI by the Forecasting Research Institute (2026) The Orthogonality Thesis (Arbital) Herbert Simon on the economics of attention (Attention economy) High Signal podcast Watch the podcast episode on YouTube Delphina's Newsletter

    53 min
  2. May 26

    Episode 40: The Economic Reality of AI: Friction, Talent, and the Future of the Firm

    Steve Tadelis, Professor of Economics at UC Berkeley and former senior economist at eBay and Amazon, joins High Signal to bridge the gap between economic theory and the high-stakes reality of data science and AI. Drawing on his experience at the forefront of the world’s largest marketplaces, Steve discusses the "invisible friction" that prevents organizations from acting on data: a combination of misaligned incentives, organizational inertia, and the "Upton Sinclair problem," where leaders are effectively paid not to understand new paradigms. The conversation moves from the "frustratingly obvious" opportunities left on the floor during eBay’s early years to the relentlessly scientific culture of Amazon. Steve explains why surface-level metrics like conversion rates often mask underlying rot in user retention and how rigorous experimentation, such as his famous $20 million search-ad experiment, can expose the difference between genuine growth and mere navigational intent. We also explore the structural shifts of the AI era, where Steve offers an important counter-narrative: rather than leveling the playing field, AI may act as an "unequalizer" that exponentially rewards those with the deepest critical thinking skills. LINKS Steve on LinkedIn Consumer Heterogeneity and Paid Search Effectiveness by Blake, Nosko, and Tadelis (Econometrica, 2015) The Limits of Reputation in Platform Markets by Nosko and Tadelis (NBER, 2015) Information Disclosure as a Matching Mechanism by Tadelis and Zettelmeyer (AER, 2015) The Anatomy of a Large-Scale Hypertextual Web Search Engine by Brin and Page (with Appendix A: Advertising and Mixed Motives) Freakonomics Radio Ep 441: Does Advertising Actually Work? (Part 2: Digital) High Signal podcast Watch the podcast episode on YouTube Delphina's Newsletter

    59 min
  3. May 12

    Episode 39: The 100-Year Lead: What Baseball Teaches Us About the Future of AI

    Chris Fonnesbeck, veteran analyst for the Yankees and Mets and creator of the open-source Bayesian modeling library PyMC, joins to unpack why baseball has been a leading indicator for data science and analytics for over a century, and why builders and AI leaders need to pay attention now. The reason it has led is simple: huge incentives and a culture that treats decisions as quantifiable. With wins worth about eight to ten million dollars apiece and front offices built around probabilistic reasoning, baseball has had every reason to push the methods further and faster than industry. The skillset and culture that built this lead is what AI teams now need to adopt more of: probabilistic thinking, hierarchical models, integrating expert judgment, reasoning carefully under uncertainty, and increasingly causal inference. The conversation traces the throughline from those early statistical innovations to the decisions driving multi-million dollar contracts today, with concrete patterns AI builders can take back to their own work: how to handle small samples and high stakes, why outcomes are the wrong thing to measure, what changes when you push uncertainty all the way through your model, and why robust causal inference needs to be the next frontier. LINKS Chris on LinkedIn The Signal and the Noise: Why So Many Predictions Fail--But Some Don't by Nate Silver Superforecasting: The Art and Science of Prediction by Tetlock and Gardner The Book: Playing the Percentages in Baseball by Tango, Lichtman, and Dolpin High Signal podcast Watch the podcast episode on YouTube Delphina's Newsletter

    56 min
  4. Apr 16

    Episode 38: Why AI Won’t Fix Your Data Culture, It Will Only Amplify It (And What To Do About It)

    Noah Bruegmann, President of Data CRT, joins High Signal to discuss how to move your data function from a cost center to a strategic "value center". He explains how AI amplifies your existing data culture, the importance of "no-assistance" reporting, and how rebranding documentation as "Context" can finally secure executive buy-in. Drawing on 15 years of experience spanning trading floors and Silicon Valley startups, Noah argues that for too long, data teams have been submerged under an "iceberg" of invisible data preparation. He details how the arrival of LLMs and agentic tools is fundamentally shifting this landscape, automating technical drudgery and allowing data professionals to transition into what he calls "Jack Ryan" mode: acting as high-level intelligence analysts rather than mere number crunchers. We dig into the architectural and psychological shifts required to navigate this new era and why the most valuable skill in an AI-augmented world is no longer mastering SQL syntax, but "problem framing": the ability to reduce business ambiguity into high-leverage insights. Noah cautions that while AI offers a dopamine hit of instant answers, it demands a new discipline of rigorous verification to avoid automated hallucinations. The conversation provides a clear directive for executives: move past the "ticket-taker" model and start treating the data team as the essential "left-side brain" for organizational decision-making. LINKS Noah on LinkedIn High Signal podcast Watch the podcast episode on YouTube Delphina's Newsletter

    46 min
  5. Mar 5

    Episode 35: Beyond Online Experimentation: Generative Software That Optimizes Itself

    Martin Tingley, Head of Windows Experimentation at Microsoft and former Head of the Experimentation Platform Analysis Team at Netflix, talks about why humans are the bottleneck in experimentation, and how a five-level maturity framework points the way toward self-optimizing software. Our conversation traces the path from basic hypothesis testing to a frontier where Generative AI creates, evaluates, and refines product variants in a closed loop. We explore the architectural shift required to move from testing single variants to optimizing entire parameter spaces, and how startups are already using AI to generate production-ready landing pages for Fortune 500 companies in hours rather than weeks. Tingley also shares a strategic lens on "experimentation programs," explaining how plotting the distribution of treatment effects across different product areas can serve as a powerful tool for capital allocation and high-level strategy. LINKS Martin on LinkedIn Want Your Company to Get Better at Experimentation? by Iavor Bojinov, David Holtz, Ramesh Johari, Sven Schmit and Martin Tingley (Harvard Business Review) Avoid the Pitfalls of A/B Testing by Iavor Bojinov, Guillaume Saint-Jacques and Martin Tingley (Harvard Business Review) Martin & Co.'s Seven Part Blog Series on Experimentation at Netflix Roberto Medri (Meta) on High Signal: The Incentive Problem in Shipping AI Products — and How to Change It Tim O’Reilly on High Signal: The End of Programming As We Know It Watch the podcast episode on YouTube Delphina's Newsletter

    55 min
5
out of 5
19 Ratings

About

Welcome to High Signal, the podcast for data science, AI, and machine learning professionals. High Signal brings you the best from the best in data science, machine learning, and AI. Hosted by Hugo Bowne-Anderson and produced by Delphina, each episode features deep conversations with leading experts, such as Michael Jordan (UC Berkeley), Andrew Gelman (Columbia) and Chiara Farranato (HBS). Join us for practical insights from the best to help you advance your career and make an impact in these rapidly evolving fields. More on our website: https://high-signal.delphina.ai/

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