Listen In - Bitesize Bio Webinar Audios

Bitesize Bio
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The Listen In podcast from Bitesize Bio is a compilation of our best webinars to enjoy at your leisure, wherever and whenever. Each episode is an opportunity to gain the valuable insights you need to advance your research. From a crash course in developing fool-proof ELISAs to the latest applications and innovations in CRISPR/Cas9 and microscopy techniques, and much more—you'll hear about challenges encountered and discover practical solutions to achieve the best possible results. Tap into the experience and expertise of leading researchers and commercial specialists to drive your research projects forward efficiently and productively. Listen In now! https://bitesizebio.com/listen-in/

  1. Detecting Rare T-Cell Responses at Scale with ELISpot and FluoroSpot

    3天前

    Detecting Rare T-Cell Responses at Scale with ELISpot and FluoroSpot

    Detecting rare antigen-specific T-cell responses requires assays that are both sensitive and scalable. Traditional methods like flow cytometry often struggle with high-throughput needs or with preserving precious sample material. In this episode of Listen In, you’ll discover how ELISpot and FluoroSpot assays overcome these challenges. These cell-based immunoassays measure cytokine and antibody secretion at the single-cell level, offering a sensitive, robust, and accessible way to capture rare immune responses. You’ll learn how ELISpot and FluoroSpot can be applied in vaccine studies, biotherapeutic evaluation, and cell and gene therapy development. The episode also explores practical guidance on assay setup and execution, the advantages of multiplex cytokine detection with FluoroSpot, and how these platforms can be qualified for use in preclinical and clinical trials. With their unique combination of sensitivity and ease of use, ELISpot and FluoroSpot provide a valuable alternative to flow cytometry, especially when high throughput and efficient data collection are priorities. Watch the full presentation here: https://events.bitesizebio.com/detecting-rare-t-cell-responses-at Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    1 小时 4 分钟
  2. From Surplus to Savings: Tackling Unused Lab Products in Life Sciences

    8月11日

    From Surplus to Savings: Tackling Unused Lab Products in Life Sciences

    In the life sciences, an astounding amount of unused products and materials end up in landfills instead of contributing to research progress. This issue arises across the product lifecycle, from liquidated biotech start-ups that abandon equipment to over-purchasing and pipeline deprioritization at successful firms. Even well-intentioned suppliers encounter forecasting challenges that leave perfectly good items discarded! In this episode of Listen In, explore the root causes of waste in our industry, as we draw on real-world examples of failed companies, discontinued pipelines, and canceled orders. We will examine the ripple effects this has on both operational efficiency and the broader sustainability goals of life science organizations. We will also introduce Wasteless Bio, a dedicated marketplace designed to keep high-quality, unused products in circulation—helping researchers access discounted reagents and instruments while reducing environmental impact. Whether you are a biotech executive, lab manager, or supplier, you will gain a clearer understanding of how to rescue valuable resources from the trash and reinvest them back into scientific innovation. Watch the full presentation here: Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    31 分钟
  3. Automated Hepatocyte Counting: New Technology for Simple, Reliable Counts

    7月7日

    Automated Hepatocyte Counting: New Technology for Simple, Reliable Counts

    Automated counting of certain cell types is notoriously challenging due to their irregular shapes, variable nuclei number, autofluorescence, and often high amounts of debris in samples. However, with the latest developments in cell-counting hardware and app technology, automated counting of even challenging cells is simpler than ever. In this episode, see how you can achieve reliable automated cell counts with the CellDrop Automated Cell Counter. Using hepatocytes as an example, you will learn how the machine learning technology integrated into DeNovix’s Hepatocyte app can save time, reduce human error, and provide consistent results. Watch the full presentation here: https://events.bitesizebio.com/automated-hepatocyte-counting-new Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    30 分钟
  4. Pioneering Biomarker Discovery In Mucinomics Through Mass Spectrometry

    6月9日

    Pioneering Biomarker Discovery In Mucinomics Through Mass Spectrometry

    In this episode of Listen In, we showcase cutting-edge mass spectrometric analysis of mucins, including the characterization of mucinases, enrichment techniques, and complete mucinomic mapping of translationally relevant mucin proteins. Mucins are a diverse family of high molecular weight glycoproteins that play critical roles in protecting and lubricating epithelial surfaces, making them integral to numerous physiological processes and disease states. As a promising class of biomarkers, mucins may offer unique insights into various pathologies, such as cancer and chronic inflammatory diseases. However, their complex structures and extensive glycosylation present significant challenges in their study and application. Mucin-domain glycoproteins are densely O-glycosylated and play key roles in many biological functions. However, their dense O-glycosylation remains enigmatic both in the glycoproteomic landscape and structural dynamics, primarily due to the challenges associated with studying mucin domains.  In this episode, you will get an introduction to the (glyco)proteomic techniques used in Mucinomics and learn how proper sample preparation of mucin-containing tissues for mass spectrometry is key to discovery. MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany. Watch the full presentation here: Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    1 小时 3 分钟
  5. How to Multiplex Any Assay: User Experience of the xMAP INTELLIFLEX®

    5月26日

    How to Multiplex Any Assay: User Experience of the xMAP INTELLIFLEX®

    In this episode, learn about latest advancements in multiplex assay technology. Hear from real user experience how the advanced xMAP INTELLIFLEX® DR-SE Instrument revolutionizes assay multiplexing, enabling simultaneous rapid data acquisition for multiple sample parameters to expand the depth and breadth of your research. Watch the full presentation here: https://events.bitesizebio.com/user-experience-of-the-xmap This compact, flow-based multiplex platform integrates xMAP® Technology with modern enhancements to streamline assay development, enhance user experience, and deliver fast, reliable results by acquiring data for two parameters per analyte simultaneously. Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    1 小时 2 分钟
  6. Inside Immunoassays: Strategies to Maximize Your Immunoassay Data and Insights

    4月28日

    Inside Immunoassays: Strategies to Maximize Your Immunoassay Data and Insights

    Immunoassays are pivotal in scientific research, enabling the precise identification and measurement of specific analytes. They pave the way for investigations into disease mechanisms, discovering biomarkers, and evaluating the efficacy of potential therapeutic interventions. The key reagents included in an immunoassay can significantly impact reliability and reproducibility, underscoring the importance of understanding critical components within immunoassay kits. When selecting an immunoassay platform, it's essential to consider critical elements such as multiplexing capabilities and sensitivity needs as part of the experimental design. Additionally, understanding the various assay formats and their data outputs can aid in the immunoassay selection process. In this episode, immunoassay experts give practical guidance in these areas, empowering researchers to achieve more precise and meaningful results, thereby advancing knowledge and understanding in various scientific fields. MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany. For Research Use Only. Not For Use In Diagnostic Procedures. Watch the full presentation here: https://events.bitesizebio.com/inside-immunoassays-strategies-to Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    37 分钟
  7. AI-Powered 3D Organoid Analysis

    3月31日

    AI-Powered 3D Organoid Analysis

    Multicolor 3D fluorescent confocal microscopy presents significant challenges in image acquisition and data analysis. However, AI is making a massive impact on 3D spatial biology. This episode of Listen In explores the incorporation of AIVIA, an AI-powered image analysis software, into workflows to address these challenges in analyzing multicolor fluorescent microscopy data of 3D organoids. See how AIVIA’s tools enhance the visualization and quantification of cellular structures and organoids, enabling precise segmentation and analysis of fluorescent signals. And get a showcase of how AIVIA supports Python-based image analysis for microscopists. Watch the full presentation here: https://events.bitesizebio.com/ai-powered-3d-organoid-analysis Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    1 小时 2 分钟
  8. High-Throughput and Wide-Range Protein Concentration Determination of Monoclonal Antibodies

    2月24日

    High-Throughput and Wide-Range Protein Concentration Determination of Monoclonal Antibodies

    In this episode of Listen In, explore high-throughput and wide-range protein concentration analysis that can deliver a 20-fold improvement in time and budget savings. Protein concentration is an obligatory critical quality attribute necessary to determine total protein content in biopharmaceutical formulations. Concentration determination is necessary before many downstream assays. A UV-based spectrophotometric assay using the protein’s extinction coefficient is the most typical method. Conventional UV methods or a specialized approach using variable pathlength slope spectroscopy could take one day to measure 15 samples in triplicate. Larger batches would require multiple analysts for a single-day turnaround time. With vast studies spanning multiple projects, protein concentration analysis becomes a key deliverable before all other methods can be performed. Thus, efficient rapid concentration analysis with a minimal volume requirement is essential. Hit play to learn how the Lunatic (Unchained Labs, Pleasanton, CA) offers rapid, plate-based concentration measurement with minimal prep and sample volume requirements. It utilizes only two microliters per sample, can analyze 96 wells in less than 12 minutes, and provides accurate measurements over a broad concentration range, from 0.03 mg/mL to 176 mg/mL. Watch the full presentation here: https://events.bitesizebio.com/high-throughput-and-wide-range/join Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

    28 分钟
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The Listen In podcast from Bitesize Bio is a compilation of our best webinars to enjoy at your leisure, wherever and whenever. Each episode is an opportunity to gain the valuable insights you need to advance your research. From a crash course in developing fool-proof ELISAs to the latest applications and innovations in CRISPR/Cas9 and microscopy techniques, and much more—you'll hear about challenges encountered and discover practical solutions to achieve the best possible results. Tap into the experience and expertise of leading researchers and commercial specialists to drive your research projects forward efficiently and productively. Listen In now! https://bitesizebio.com/listen-in/

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