Beyond the Endpoint

Duke Clinical Research Institute

The Duke Clinical Research Institute is drawing on gold-standard research and real-world evidence to bring you Beyond the Endpoint, a podcast that is demystifying clinical research and healthcare through conversations with renowned clinicians and scientists.

  1. Beyond the Headlines: PMDD and Antihistamines, Real-Time FDA Study Monitoring Using Al, and More!

    May 13

    Beyond the Headlines: PMDD and Antihistamines, Real-Time FDA Study Monitoring Using Al, and More!

    In this Beyond the Headlines episode, we examine the FDA's push for real-time clinical trial data, an executive order making psychedelic research a federal priority, advances in CAR T-cell therapy for autoimmune conditions, and viral claims about antihistamines as a treatment for premenstrual dysphoric disorder. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-16-beyond-headlines

    25 min
  2. The COPD Gap: Diagnosis, Treatment, and Access

    Apr 22

    The COPD Gap: Diagnosis, Treatment, and Access

    COPD is the third leading cause of death worldwide. Yet the disease remains underdiagnosed and underfunded. Host Emily O'Brien and pulmonologist Chris Mosher discuss stigma, funding disparities, barriers to care, and promising research that's bringing new hope to patients. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-15-copd-gap-diagnosis-treatment-and-access

    35 min
  3. Hard Habits: What Kidney Stones Teach Us About Behavior Change

    Apr 8

    Hard Habits: What Kidney Stones Teach Us About Behavior Change

    Why is it so hard to change our behavior, even when we know what we should be doing? Host Emily O'Brien sits down with urologist and DCRI faculty member Dr. Chuck Scales to discuss the science of behavior change and surprising findings from the PUSH trial, the largest kidney stone prevention trial to date. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-14-hard-habits-what-kidney-stones-teach-us-about-behavior-change

    24 min
  4. Closing the Gap in Cardiac Arrest Survival: Why Bystanders Matter

    Mar 11

    Closing the Gap in Cardiac Arrest Survival: Why Bystanders Matter

    During a cardiac event, every minute without CPR reduces survival chances by 10%. In this episode, DCRI's Tyler Cope discusses a coordinated effort to train nearly 20,000 people across North Carolina in a single day and what it takes to get more bystanders to take action in an emergency. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-13-closing-gap-cardiac-arrest-survival-why-bystanders-matter

    29 min
  5. From Research to Relief: Raising the Standard in Back Pain Treatment

    Feb 25

    From Research to Relief: Raising the Standard in Back Pain Treatment

    Nearly 40% of Americans have experienced back pain in the past three months, yet treatment hasn't kept pace with the science. Host Emily O'Brien talks with DCRI researcher Steven George about biopsychosocial models of care, pragmatic trials, and building a better system for chronic pain management. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-12-research-relief-raising-standard-back-pain-treatment

    34 min
  6. All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin

    Feb 11

    All About Allergies: The Evolution of Care & Evidence with Dr. Zach Rubin

    Double-board-certified pediatrician and allergist/immunologist Zach Rubin joins Manesh Patel for an evidence-based discussion on allergy science. The conversation dives into the differences between allergies and sensitivities, recent shifts in food allergy prevention, environmental and metal allergies, and FDA-approved treatments, including Xolair and needle-free EpiPens. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-11-all-about-allergies-evolution-care-evidence-dr-zach-rubin

    31 min
  7. From Innovation to Implementation: AI in Action

    Jan 28

    From Innovation to Implementation: AI in Action

    Guests Michael Pencina and Suresh Balu join the Beyond the Endpoint hosts to explore the impact of AI in healthcare. They discuss the role of AI-powered tools in research, clinical care, and operations, while examining evidence standards, transparency challenges, and the potential evolution of the physician-patient relationship. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-10-innovation-implementation-ai-action

    26 min
  8. Beyond the Headlines Series: Looking back at 2025 headlines, Dementia & Vaccines, and Cannabis Research

    Jan 14

    Beyond the Headlines Series: Looking back at 2025 headlines, Dementia & Vaccines, and Cannabis Research

    Kick off 2026 with hosts Manesh Patel and Emily O'Brien as they evaluate last year's most discussed health stories and wellness trends, cannabis reclassification, and a shingles vaccine-dementia study. 🔗 Access resources related to this episode: https://dcri.org/blog/s2-ep-9-beyond-headlines

    21 min
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Ratings & Reviews

3
out of 5
2 Ratings

About

The Duke Clinical Research Institute is drawing on gold-standard research and real-world evidence to bring you Beyond the Endpoint, a podcast that is demystifying clinical research and healthcare through conversations with renowned clinicians and scientists.

Information

  • Creator
    Duke Clinical Research Institute
  • Years Active
    2017 - 2026
  • Episodes
    48
  • Rating
    Clean
  • Copyright
    © All rights reserved
  • Show Website
    Beyond the Endpoint

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