Tacos and Tech Podcast

Neal Bloom

The Tacos and Tech Podcast highlights the builders of companies, technologies, ecosystems with a local flair for our lifestyle as well. risingtidepartners.substack.com

  1. JAN 5

    This Week in San Diego Tech News - 1/5/2026

    Listen & subscribe on Apple, Spotify, YouTube. Welcome everyone to the weekly San Diego Tech News! I’m Neal Bloom from Rising Tide Partners. My co-host in this episode is Fred Grier, journalist and author of The Business of San Diego substack. He covers the ins-and-outs of the startup world including breaking news, IPOs, fundraising rounds, and M&A through his newsletter. Before we dive in, we wanted to thank and ask our listeners to help us grow the show, leave a review and share with one other person who should be more plugged in with the SD Tech Scene. Thank you for the support and for helping us build the San Diego Startup Community! 1/5/2026 Draft numbers of total VC Investment into SD Companies in 2025: $3.4B Select top fundings: * Tech: * ShieldAI $240M, Cybereason $120M, Flock Fleight $60M, Clearspeed $60M, FABRIC8LABS $50M, Equip $46M * Biotech: * Crystalis Therapeutics $205M; Timberlyne Therapeutics $180M; Protego Biopharma $130M; Aspen Neuroscience $115M; Raythera $110M 2025 Acquisitions: * Avidity $12B by Novartis * Cidara Therapeutics $9.2B Merck * Capstan Thera $2.1B by AbbVie * Arthrosi Thera $1B * Kate Thera $1.1B * Regulus Therapeutics acquired by Novartis ($1.7B) * Nalu Medical $500M IPOs: * Aardvark Thera * Aptera * Once Upon A Farm * Carlsmed * MapLight Therapeutics 2026 Predictions * More IPOs & M&A, market up * Fundings up, in specific areas, more in other markets than SD * More return to office, in specific areas Carta Startup Ranking - San Diego #6 Trust & Will Holiday Bowl TED announced move to SD Curated Events List – For full list – check The Social Coyote CES - Jan. 5-10 Carlsbad Industry Exchange - Jan. 6 JPM - Jan. 12-15 State of Venture event - Jan. 29 This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit risingtidepartners.substack.com/subscribe

    41 min
  2. San Diego Angel Conference – Investor Education & Networking Series

    12/23/2025

    San Diego Angel Conference – Investor Education & Networking Series

    In this special episode, we bring you a practical, high-context walkthrough of early-stage investing hosted by the San Diego Angel Conference (SDAC). With insights from the Pillsbury ECVC legal team and SDAC organizers, this session offers angel investors - both new and experienced - a clear breakdown of key financing instruments like SAFEs, convertible notes, and priced equity rounds. We cover the structure and implications of different entity types (C-Corps, LLCs, S-Corps), the nuance behind valuation caps and discounts, the benefits of pro rata rights, and the tax advantages of Qualified Small Business Stock (QSBS). Whether you’re gearing up for Fund 8 or thinking about writing your first check, this session equips you with the frameworks and real-world insights you need to invest smarter. Key Topics Covered * Why SDAC is building year-round investor education & networking events * Overview of startup legal structures: LLCs vs. C-Corps (and why Delaware still leads) * What investors should understand about SAFE agreements * How post-money valuation caps really work (and how they differ from discounts) * Why side letters can protect your upside: pro rata, info rights, MFNs, and more * How convertible notes differ from SAFEs and when they might be preferable * Real red flags on cap tables and what they tell you about a company’s past * What to know about Zombie SAFEs (and how to avoid them) * Tax advantages of Qualified Small Business Stock (QSBS) and recent updates to eligibility * The evolving dynamics of angel rounds, bridge financing, and recapitalizations Links & Resources * San Diego Angel Conference Website * Qualified Small Business Stock Overview – IRS This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit risingtidepartners.substack.com/subscribe

    1h 3m
  3. Building Biolinq

    12/16/2025

    Building Biolinq

    In this episode of the Tacos & Tech Podcast, host Neal Bloom sits down with Jared Tangney, co-founder and CTO of Biolinq. From their early EvoNexus days to today’s FDA clearance, Jared walks us through the incredible journey of Biolinq - how it pivoted from sweat-sensing tattoos to a revolutionary microneedle platform that can measure glucose, lactate, and even cortisol with no blood and no pain. Jared shares how a Mailchimp newsletter led to their first investor, Mark Cuban, and why he believes San Diego is the global epicenter for biosensing innovation. With a focus on serving the largest segment of the diabetes population and plans to expand into broader metabolic and stress biomarkers, Biolinq is changing what’s possible in wearable health tech. Key Topics Covered: * How Biolinq’s microneedle platform works and why it matters * From sweat-based sensors to skin-based semiconductors * Lessons from nearly a decade of R&D and pivots * Measuring glucose, lactate, and now cortisol - what’s next? * How a newsletter sign-up brought Mark Cuban in as the first investor * Navigating FDA clearance and commercialization strategies * San Diego’s competitive edge in biosensing, diabetes tech, and medical wearables * The growing importance of AI and multi-analyte sensing in personal health * Reflections on community, startup persistence, and tacos (Fish 101 for the win) Links & Resources:Learn more about Biolinq Connect with Jared Tangney:LinkedIn This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit risingtidepartners.substack.com/subscribe

    48 min
  4. Burbank Tech Talks - Looking Ahead in Media

    12/09/2025

    Burbank Tech Talks - Looking Ahead in Media

    In this special live episode of the Tacos & Tech Podcast, we take you inside the latest Burbank Tech Talk event, recorded at Tailored Space in the heart of the Media Capital of the World. This panel brought together creators, founders, and technologists to explore the fast-shifting landscape of entertainment, gaming, and AI—and what it means for the future of storytelling, monetization, and creativity. From visual effects to streaming-era music deals to real-time game personalization powered by AI, this episode dives into what’s working now, what’s being disrupted, and what’s coming next. Whether you’re a founder, artist, developer, or fan of the future, you’ll walk away with clear-eyed insights on where media and tech are headed. In this episode, we cover: * Why AI is more workflow revolution than job replacement—and how creators are adapting * The rise of AI-as-inspiration in music, gaming, and film * How independent creators can build real businesses with the new tools (if they think like founders) * Why monetization and royalties are still the biggest friction points in music tech * What’s coming next: global content, micro-audiences, and curated experiences in the AI era * The growing importance of local innovation ecosystems like Burbank in a rapidly decentralized creative economy Featured Speakers: * Nova Renay– Host and moderator, composer, producer, and creative technologist * George Karalexis and Donna Budica of Ten2 – Music entrepreneurs helping artists monetize through content transparency and UGC * Alan Lasky – Former VFX and studio exec, speaking on the evolution of visual effects and media economics * Cody Germain – Founder of Bear Club Games, previously at Riot and Epic Games, sharing how AI is transforming real-time gameplay and player experience Key Topics Covered: * The myths vs. realities of AI in creative work * How generative tools like Suno and Sora are being used behind the scenes by major producers * AI in game engines, browser-based games, and new distribution channels * The death of theatrical? What it means for local film production * Independent vs. major label artist trajectories in the TikTok era * The opportunity for cities like Burbank to lead through local investment in experimentation, talent, and infrastructure Links & Resources: * Tailored Space – coworking host location * Burbank Economic Development Division * Ten2 Media * Rise and Tide Partners * Upcoming Burbank Events: * Burbank Tech Talks: [Tech, Talent & the New Learning Economy] – January 20, 2026 Watch the Recording: 📺 Full Video Link🎬 Event Recap Teaser Clip This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit risingtidepartners.substack.com/subscribe

    1h 6m
5
out of 5
37 Ratings

About

The Tacos and Tech Podcast highlights the builders of companies, technologies, ecosystems with a local flair for our lifestyle as well. risingtidepartners.substack.com

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