Prevention is Cure

PREKURE - Prof Grant Schofield
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How do we live a life worth living? Prof Grant Schofield dives deep into the lessons, science, and habits that define human flourishing. From reversing chronic disease to the psychology of behaviour change, he interviews the leading experts to help you navigate the complexities of the modern world. It’s time to stop managing sickness and start building a better version of yourself. Powered by prekure.com

  1. May 17

    #44 The Amplified Mind: How to Stay Human in the Age of AI

    Prof Grant Schofield speaks with Paul Alden, a 38-year veteran firefighter turned author about his upcoming book The Amplified Mind. Drawing on his experience watching EMTs lose critical thinking capacity when protocols replaced diagnostic reasoning, Paul draws a striking parallel to what's happening right now with AI adoption across every profession. They explore why the sequence matters, generating your own ideas before turning to AI, and how "synthetic fluency" is quietly eroding our agency, creativity, and capacity to learn. From the five-minute rule to the Google Effect, Paul shares practical disciplines for staying the author of your own thinking rather than becoming an editor of AI output. The Amplified Mind is available on Amazon from May 26th. Pre-order from May 22nd at theamplifiedmind.ai.

    1h 3m

  2. May 12

    Paul Taylor Podcast: Choose your hard: Science-backed strategies to thrive in a difficult world, with Emeritus Professor Grant Schofield

    From the Hardiness podcast with Dr Paul Taylor If you think ease and comfort are the keys to happiness, think again. This episode explores how deliberately embracing life's challenges, through movement, fasting, cold exposure, and mental resilience, can transform your health, happiness, and purpose. Grant Schofield, an esteemed researcher and author, reveals that life's true reward lies in choosing the hard path, strong in the knowledge that it leads to a more vibrant, resilient life.        Choose your path, and in doing so, choose your future. And for those ready to take action, Grant’s new book Choose Your Hard distils these powerful principles into actionable step because the path to a better life is a deliberate choice. 00:00 The Role of an Emeritus Professor 02:57 The Academic Publishing Industry 05:54 Understanding Misogi and Personal Challenges 09:00 Fasting and Autophagy Explained 12:01 The Science of Metabolism and Immune Function 15:04 Psychological Aspects of Fasting 17:58 Preparing for a Fast: Strategies and Mindset 20:58 Physical Responses and Adaptations During Fasting 25:51 The Role of Stress in Health 27:28 Choosing Your Hard: Embracing Life's Challenges 35:19 Agency and Responsibility in Health 40:10 Movement: The Foundation of Health 46:43 Dopamine: The Devil's Seesaw 52:41 Hard vs. Soft Dopamine: Resetting the System 53:28 The Irony of Pleasure and Pain 55:24 Facing the Elements: Hot and Cold Exposure 01:01:38 Understanding Emotions and Their Ownership 01:05:18 Finding Meaning and Purpose in Life

    1h 21m

  3. May 4

    #43 The Placebo Effect: The Most Underrated Tool in Health & Performance

    Prof Grant Schofield is joined by Sam Schofield on this episode that dives deep into the placebo, and 'nocebo' effect, exploring how belief, self-narrative, and perceived feedback can measurably change your physiology, performance, and recovery. From Roger Bannister's four-minute mile to sham knee surgeries, sleep score dangers, and the milkshake study, this episode makes the case that the mind is the most underused lever in health and medicine.

    37 min

  4. Apr 28

    #42 The Hormonal Orchestra: Why Willpower Isn't Enough to Manage Hunger

    Prof. Grant Schofield and Kayla dive into the science and break down the five key hormones controlling appetite, insulin, leptin, ghrelin, the incretins (GIP & GLP-1), and cortisol and explain why willpower alone can never beat a dysregulated hormonal system. They explore metabolic flexibility, why cycling in and out of ketosis is normal human physiology (not a fad), and how exercise context should drive your fuelling strategy.

    44 min

  5. Apr 19

    #41 The Science of doing hard sh*t to build health that lasts a lifetime

    What if the secret to a long, healthy life isn't making things easier, it's choosing the right kind of hard? In this episode, Prof. Grant Schofield and Kayla sit down to celebrate the launch of Grant's new book, Choose Your Hard: The Science of Doing Hard Sh*t to Build Health That Lasts a Lifetime. They unpack the seven truths behind lasting health and performance, from the biology of hormesis and the dopamine trap, to nutrition, facing the elements, managing distraction, owning your emotions, and finding meaning. Whether you're a high performer or just starting out, this episode will challenge you to stop chasing the easy path and start choosing your hard, deliberately and with purpose.

    1h 7m

  6. Apr 12

    #40 You Can't Supplement Your Way Out of This: AI, Ultra-Processed Thinking & the Root Causes of Poor Health

    Grant and Kayla follow up on Claude's viral AI essay with Claude's own response, they unpack new research on AI-induced "delusional spirals," a Nobel laureate economist's dire warning about AI and human thinking, and the cultural moment we're in with films like WALL-E and Good Luck, Have Fun, Don't Die. Then stay tuned to hear about nutrition: the omega-3 to omega-6 ratio crisis, a landmark 1.8-million-person study on vegan diets and colorectal cancer, why minced beef may build muscle better than steak in older adults, and the sobering reality that modern fruits and vegetables contain a fraction of the nutrients they did in 1950.

    51 min

  7. Apr 5

    #39 The 5 New Game-Changing Health Studies: Exercise, Sunlight, Fasting, Social Media & AI

    Prof. Grant Schofield and Kayla dive into five groundbreaking scientific papers that challenge conventional wisdom about health and technology. Discover why exercise signals your entire body to heal, how Swedish women who avoided sunlight faced mortality risks equal to smoking, and why eating earlier in the day beats traditional intermittent fasting. Plus: the shocking evidence proving social media harms teens (backed by Meta's own leaked documents), and why AI is dangerously designed to always agree with you, even when you're wrong.

    30 min

  8. Mar 29

    #38 Why You Should Give A Sh*t About Fibre

    Is fibre actually the health hero we've been told it is? Prof. Grant Schofield and Kayla dive deep into the science behind fibre recommendations and expose how food companies game the system. From the surprising truth about constipation to why cows eating grass end up on a high-fat diet, this episode challenges everything you thought you knew about fibre.Key Takeaways:• Why dietary fibre guidelines might be doing more harm than good• How food manufacturers add fibre to junk food to make it seem healthy• The real reason people in East Africa had fewer chronic diseases (spoiler: it wasn't just fibre)• What happened when researchers put people on a ZERO fibre diet for constipation• Why focusing on "eat real food" beats obsessing over fibre gramsTimestamps0:05 - Introduction: The least sexy topic in nutrition science1:09 - Why dietary guidelines actually matter (hospitals, schools, prisons)2:19 - The three big nutrition mistakes: saturated fat, red meat, and salt6:19 - The "giant scrubbing brush" theory and where the fiber hypothesis came from7:37 - The Inuit counter-argument: No fibere, no disease8:44 - Leaded petrol: The confounding variable everyone forgot12:06 - The donut fibre scam: How food companies game health ratings15:33 - Understanding relative vs absolute risk (the 1% reality check)17:29 - Two plausible mechanisms: The viscous gel pathway18:55 - Short chain fatty acids and gut bacteria19:54 - Cows and gorillas: The high-fat diet from grass23:30 - The constipation paradox: Does fiber actually help?24:51 - The zero fibre diet study that shocked everyone26:08 - Mendelian randomization: The "genetically predicted fiber intake" problem31:30 - Vision of the anointed: When interventions fail, do more of the same33:03 - The Women's Health Initiative: The biggest fiber trial that did nothing36:30 - What to do instead: Focus on ultra-processed food41:08 - Three take-home messages about fiber42:00 - Grant's simple dietary guidelines43:04 - The farting observation: What your body tells you about fiber43:59 - Post-episode: What should you actually change?

    46 min
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About

How do we live a life worth living? Prof Grant Schofield dives deep into the lessons, science, and habits that define human flourishing. From reversing chronic disease to the psychology of behaviour change, he interviews the leading experts to help you navigate the complexities of the modern world. It’s time to stop managing sickness and start building a better version of yourself. Powered by prekure.com

Information

  • Creator
    PREKURE - Prof Grant Schofield
  • Years Active
    2018 - 2026
  • Episodes
    52
  • Rating
    Explicit
  • Copyright
    © PREKURE - Prof Grant Schofield
  • Show Website
    Prevention is Cure

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