Happy & Healthy with Amy

Amy Lang

Do you want to protect your brain from Alzheimer's disease so you can be sharp and stay sharp for life? This podcast is for you.Your host, Amy Lang, master certified health coach and founder of Moxie Club will be sharing with you the lessons learned and insights gained from 20+ years as a health club owner and Alzheimer's prevention coach.For more information, visit www.moxie-club.com

  1. 6d ago

    Alzheimer’s Risk in Women vs. Men: What’s Different

    If your mom was diagnosed with Alzheimer’s, you may already be wondering, “Am I next?” But if your dad, husband, brother, or partner is the one you’re worried about, this episode is for you too. Amy breaks down the differences in Alzheimer’s risk in women and men, including why women carry more modifiable risk factors, why certain risk factors may hit women’s cognition harder, and why Alzheimer’s may show up in men in ways that can blindside you. What to Listen For [00:00] Why this episode is for women and the men they love [02:00] Why “early is everything” in Alzheimer’s prevention [05:00] Why women’s Alzheimer’s risk is not just about longevity [07:00] The UC San Diego study findings that surprised researchers [10:00] The 13 modifiable dementia risk factors studied [12:00] Who carries more risk factors versus who is more affected by them[15:00] How BMI affects cognitive performance differently in women vs men [18:00] What you need to know about the effects of cholesterol management [22:00] How heart health affects Alzheimer’s risk in men[27:00] What behavioral symptoms show up more often in men with Alzheimer’sOver 7.2 million adults in the U.S. have clinical Alzheimer's, and 2 out of 3 are women. But men are not immune, and there are significant differences. Knowing what they are and which modifiable risk factors to pay attention to means more effective prevention as well as treatment. Listen to the full episode, subscribe to Happy and Healthy with Amy, and download Amy’s free RESTORED Protocol guide so you can start building an Alzheimer’s-resistant brain—one habit at a time. RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    29 min

  2. Jun 3

    Neuroinflammation and Brain Health: 8 Steps To Protect Your Brain in Midlife

    What if amyloid is only the match, tau is the brush fire, and neuroinflammation is the wildfire that causes the most damage in Alzheimer’s disease? In this episode of Happy & Healthy with Amy, Amy explains why researchers are paying closer attention to neuroinflammation, what may be keeping the brain’s immune system stuck in the “on” position, and why midlife is such an important window for protecting your brain. You’ll learn how sleep, blood sugar, chronic stress, infections, oral health, and social connection may all influence the conditions that make the brain more—or less—flammable. What to Listen For [00:00] Why amyloid may be the match—but neuroinflammation is the wildfire. [02:30] What the Cochrane review found about anti-amyloid drugs. [04:30] Why timing matters in Alzheimer’s disease. [07:00] Is neuroinflammation a side effect—or a driver? [09:00] Why inflammation itself is not the villain. [11:00] Meet microglia: the brain’s immune cells. [14:00] Why gum disease matters for Alzheimer’s risk.[18:00] The shingles vaccine and dementia risk. [22:00] Blood sugar, insulin resistance, stress, and sleep. [29:00] How to make your brain less “flammable.” Neuroinflammation may be one of the most important pieces of the Alzheimer’s prevention puzzle because it connects so many things we often treat separately: sleep, stress, blood sugar, oral health, infections, diet, and connection. Listen to the full episode to understand what may be making your brain more “flammable,” then download the free RESTORED Protocol so you can choose one simple, evidence-based next step for protecting your brain. Mentioned in The Episode Download the RESTORED ProtocolDownload The First Steps Guide for supporting a parent after Alzheimer’s diagnosisRelated Episodes Alzheimer’s Prevention: What the Cochrane Review MeansAlzheimer’s Drugs: Why Amyloid Removal May Not Be EnoughGum Disease, Menopause & Your Alzheimer's RiskSources RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    26 min

  3. May 27

    Alzheimer’s Drugs: Why Amyloid Removal May Not Be Enough

    If your parent was recently diagnosed with Alzheimer’s, you may have heard about the latest Alzheimer’s treatments - Kisunla and Lequembi - being described as breakthrough "disease-modifying" drugs. And yes, the science is promising in some ways. But here’s the part most families are not told clearly: a drug may successfully remove amyloid from the brain and still not create a meaningful improvement in memory, thinking, reasoning, or day-to-day function. In this episode, Amy explains why. This is not medical advice. It is education designed to help you ask better questions, advocate more clearly, and make decisions with your eyes wide open. You’ll learn what happens in the brain long before symptoms appear, why amyloid is only one part of the Alzheimer’s disease process, and why tau, neuroinflammation, and neurodegeneration matter so much when you’re trying to make informed decisions for someone you love. What to Listen For [00:00] Why amyloid removal may not translate into meaningful improvement. [02:00] What the Cochrane review found about anti-amyloid drugs. [04:30] Why memory problems are not the beginning of Alzheimer’s. [07:00] The Alzheimer’s disease timeline. [10:00] Why treating amyloid after symptoms appear may be too late. [12:30] What tau does in healthy brain cells. [14:00] What tracks closely with cognitive decline. [16:30] What ARIA is and why it matters. [18:00] The role of neuroinflammation in Alzheimer’s.[22:00] Questions to ask the neurologist before deciding. Mentioned in the Episode Alzheimer’s Prevention: What the Cochrane Review MeansCochrane Review: Anti-amyloid Alzheimer’s drugs show no clinically meaningful effectListen now, subscribe to Happy & Healthy with Amy, and share this episode with someone who is trying to make sense of an Alzheimer’s diagnosis in their family. RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    30 min

  4. May 20

    How to Build an Alzheimer’s Care Team

    If your mom or dad was recently diagnosed with Alzheimer’s, you may already feel the weight of caregiving starting to land on your shoulders. But here’s the good news: being the primary caregiver does not mean doing it alone. In this episode of Happy & Healthy with Amy, Amy walks you through how to build an Alzheimer’s care team early, before caregiving by default becomes an unwanted reality. You’ll learn who belongs on the team, what each person holds, and how to ask for help without feeling like you’re begging people to care.  What to Listen For 01:20 — What caregiving in the Alzheimer's space actually means03:00 — How caregiving by default happens 04:45 — Why building a care team is also prevention06:30 — The three professional anchors10:00 — How the neurologist helps you understand the brain-specific picture and future options. 12:15 — Why asking for a social worker may be the one question that changes everything. 15:30 — The one-page care team note that keeps everyone from relying on your memory alone. 18:00 — How to ask family and friends for help so you don't feel like you're beggingBuilding an Alzheimer’s care team early is one of the most loving and practical things you can do for your parent, your family, and yourself.  Listen to this episode now, then subscribe to Happy & Healthy with Amy and download the free guide, Mom Was Diagnosed with Alzheimer’s. Now What? Resources from the Episode Alzheimer’s Association: https://www.alz.orgAlzheimer’s Association 24/7 Helpline: 800-272-3900 ALZConnected: https://www.alzconnected.orgCaregiver Action Network: https://www.caregiveraction.orgAging Life Care Association: https://www.aginglifecare.orgAmy's Free Guide: https://www.amylangcoaching.com/firststepsRecommended Complimentary Episodes My Mom Was Diagnosed with Alzheimer’s. Am I Next? — This is the natural starting point for listeners who are scared that a parent’s diagnosis means their own future is already written. It covers family history, modifiable risk factors, menopause, and the first five brain-health moves Amy recommends. After an Alzheimer’s Diagnosis: A Family Checklist — A strong companion episode because it walks families through the first practical questions to ask after diagnosis, including how to move from panic into grounded action. Alzheimer’s Prevention: What the Cochrane Review Means — Helpful for listeners trying to make sense of scary headlines, anti-amyloid drugs, and what “clinically meaningful” really means for Alzheimer’s prevention. GLP-1s and Alzheimer’s Prevention: Hope or Hype? — A good fit for midlife women hearing about GLP-1s, APOE4, and dementia risk and wanting a more grounded way to evaluate the hype. The Menopause–Alzheimer’s Link: How to Protect Your Brain Health Now — Recommended for women in perimenopause or menopause who want to understand why this transition matters for cognitive health. RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    31 min

  5. May 13

    After an Alzheimer’s Diagnosis: A Family Checklist

    If your mom or dad was just diagnosed with Alzheimer’s, your brain may be trying to solve everything at once. What does this mean? How fast will it progress? Are they safe? What questions should you ask? And what are you supposed to do first? In this episode of Happy & Healthy with Amy, Amy walks you through a a practical checklist to help you move from panic and overwhelm into clarity, grounded action, and better advocacy. Think of it like a pre-flight checklist for one of the hardest journeys your family may ever take.  What to Listen For [00:00] The 47-tabs-at-3-a.m. feeling after a parent’s Alzheimer’s diagnosis [01:35] Why you don't need to feel guilty for thinking about your brain health[04:45] The three roles you may suddenly be carrying[06:20] Two grounding questions to calm your nervous system[08:30] How to make sense of the diagnosis [11:00]  The questions to bring to the next neurologist appointment[14:00] Why the prescription is not the whole plan[20:00] Why Alzheimer’s is not just memory loss[24:30]  The grief underneath the diagnosis[29:00] The hard conversations to start earlyAn Alzheimer’s diagnosis can feel overwhelming, but you do not have to figure everything out today. Start with what you know for sure, choose one next step, and use this episode as your checklist for asking better questions and supporting your parent with love in practical form.  Resources Mentioned My Mom Was Diagnosed with Alzheimer's. Am I Next? (Season 2, Episode 39)Early Is Everything: How Blood Tests Offer New Hope (Season 1, Episode 278)The Latest Alzheimer's Treatments: What Works, What Doesn't, and What's Next - 2025 Update (Season 1, Episode 274)Protect Your Brain with the MIND Diet: Essential Tips for Brain Health (Season 1, Episode 256)The Critical Role of Sleep in Alzheimer's Prevention (Season 1, Episode 249)The 5 As of Alzheimer's Progression: Beyond Memory Loss (Season 2, Episode 17)Listen now, subscribe to Happy & Healthy with Amy, and come back for the next episode on how to build a care team. RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    34 min

  6. May 6

    My Mom Was Diagnosed with Alzheimer's. Am I Next?

    If your mom or dad was just diagnosed with Alzheimer's, you're probably wondering: am I next? Watching a parent receive this diagnosis can make every forgotten word, every misplaced key, every moment of brain fog feel suddenly loaded with meaning. In this episode, Amy answers the question directly — with science, with compassion, and with her own deeply personal experience of watching two generations of her family navigate Alzheimer's. What You'll Learn What family history actually means for your Alzheimer's risk (and why genes are not destiny)Why most cases of Alzheimer's involve far more than genetics — and what that means for youWhat the Lancet Commission's July 2024 report found about modifiable risk factors (the number will surprise you)Why the menopause transition is one of the most important windows for protecting your brainWhy menopause brain fog is not the same as dementia — and what it is telling youThe first 5 brain-health moves Amy would make if she were starting from scratch todayWhat to Listen For 00:00 — Why a parent’s Alzheimer’s diagnosis can make normal forgetfulness feel terrifying. 01:00 — The message Amy wants you to hear first: family history is not destiny. 02:30 — Amy’s personal story of her mother’s diagnosis and the moment that changed everything. 06:30 — What family history actually means for Alzheimer’s risk. 08:00 — Why late-onset Alzheimer’s is influenced by more than genetics. 09:30 — The Lancet Commission’s 14 modifiable dementia risk factors and why that number matters. 11:00 — APOE4, women, and why genes are information — not a foregone conclusion. 13:00 — Why menopause is a brain-body transition, not just a reproductive transition. 17:00 — Why panic research usually creates more anxiety, not more safety. 19:00 — The first five brain health moves: sleep, blood sugar, movement, stress recovery, and connection. 30:44 — The Larry Wall quote Amy uses to remind us that the future is shaped one present-moment choice at a time.Resources mentioned in this episode: Free RESTORED Protocol Guide → amylangcoaching.comYour parent’s diagnosis may feel like a glimpse into your future, but it is not a foregone conclusion. Your story does not have to be a repeat of your parent’s story. Listen to this episode to learn the first five moves Amy recommends for Alzheimer’s prevention, then choose one habit to focus on first. Subscribe to Happy & Healthy with Amy so you don’t miss next week’s episode. Next episode: How to Advocate for a Parent Newly Diagnosed with Alzheimer’s RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    33 min

  7. Apr 29

    Alzheimer’s Prevention: What the Cochrane Review Means

    Have you seen the headlines about anti-amyloid Alzheimer’s drugs showing “no clinically meaningful effect”? If some you love has been diagnosed with Alzheimer’s, that kind of headline can feel like a gut punch. But before you fall into the pit of despair — or pin your hopes on the next promising treatment — you need to about this essential tool called the hierarchy of evidence so you know how to interpret the evidence for yourself. In this episode, Amy breaks down the hierarchy of evidence, explains what the latest Cochrane review actually found, and shows you how to separate meaningful science from scary headlines and health influencer hype. What to Listen For 00:00 — Why the latest anti-amyloid Alzheimer’s drug headlines are so easy to misread 02:35 — The hierarchy of evidence: what it is, why it matters, and how it helps you spot hype 04:50 — Why animal studies can be useful—but should not be treated like proof of what happens in women 07:20 — The difference between correlation and causation, using Chanticleer the rooster as a very memorable example 09:05 — What the “moderate drinking is good for your heart” story teaches us about confounding variables 12:15 — Why GLP-1s and dementia risk are more complicated than the headlines suggest 14:30 — Mechanistic versus clinical evidence, and why something can make sense biologically but still fail in real life 16:10 — The difference between “statistically significant” and “clinically meaningful”—and why that distinction matters for Alzheimer’s prevention 20:30 — What the Cochrane review actually found about anti-amyloid Alzheimer’s drugs 27:45 — Why removing amyloid is not the same as preserving memory, independence, or quality of life 31:30 — The lifestyle habits that still offer the clearest, most empowering path for Alzheimer’s preventionThe big takeaway? Don’t let a headline—or an influencer—tell you what the evidence means. The better you understand the hierarchy of evidence, the easier it becomes to stay curious, grounded, and empowered. 📥 Download the free RESTORED Protocol for the essential 8 evidence-based lifestyle factors for brain health at moxie-club.com/restored Listen to the full episode to learn how to interpret Alzheimer’s prevention research with “new eyes,” then subscribe to Happy & Healthy with Amy and download the free RESTORED Protocol guide to take one clear next step for your brain health. RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    34 min

  8. Apr 22

    GLP-1s and Alzheimer’s Prevention: Hope or Hype?

    When Penn Holderness described APOE4 as a “ticking time bomb,” it struck a nerve for a lot of people, especially women in midlife who already feel vulnerable about their brain health. Could a GLP-1 medication protect your brain if you carry the APOE4 gene? Amy unpacks the science in plain English and explains why genes are not destiny, why menopause changes the conversation for women, and what research-backed actions you can start taking right now. What to Listen For [00:00] Why Penn Holderness’s APOE4 reveal sparked such a big reaction  [02:30] What it actually means to carry one or two copies of the APOE4 gene  [05:30] Why APOE4 is a genetic predisposition, not a verdict  [08:30] The critical difference between APOE4 and the rare genes that directly cause early-onset Alzheimer’s  [10:30] Why midlife and postmenopausal women may face a different level of APOE4-related risk  [14:00] How fear drives people toward quick-fix solutions and why that matters in Alzheimer’s prevention  [18:00] What the observational GLP-1 research shows and the big caveat most people miss  [22:00] What the EVOKE and EVOKE Plus semaglutide trials found in people with early Alzheimer’s symptoms  [25:30] What hormone therapy can do for sleep and symptom relief — and what it has not been proven to do for dementia prevention  [28:30] Why the FINGER study, U.S. POINTER, and modifiable risk-factor research offer the most hopeful path forward  [32:30] The free RESTORED guide, the 8 evidence-based lifestyle factors, and Amy’s call to take action without panic If you’ve been feeling afraid of your genetic risk, this episode is your reminder that APOE4 is not destiny. Amy explains why the most powerful path forward is still grounded in the basics: sleep, movement, metabolic health, stress management, and consistent daily choices. Listen now, subscribe to the show, and grab Amy’s free guide so you can start protecting your brain one step at a time. From The Episode Download the free RESTORED ProtocolBook your Breakthrough Roadmap sessionResearch cited in this episode: 1. NIA Alzheimer's Disease Genetics Fact Sheet — APOE4 prevalence and risk breakdown https://www.nia.nih.gov/health/alzheimers-causes-and-risk-factors/alzheimers-disease-genetics-fact-sheet 2. Altmann A et al. (2014). Sex modifies the APOE-related risk of developing Alzheimer disease. Annals of Neurology. https://pmc.ncbi.nlm.nih.gov/articles/PMC4117990/ 3. Stanford Medicine (April 2026). Women get Alzheimer's more often than men: Five things the science tells us. https://med.stanford.edu/news/insights/2026/04/women-alzheimers.html 4. Alzheimer's Association (2025). Statement on oral semaglutide phase 3 topline data (EVOKE/EVOKE+ trials). https://www.alz.org/news/2025/alzheimers-association-statement-oral-semaglutide-phase-3-topline-data-release 5. Ngandu T et al. (2015). FINGER Study. The Lancet, 385(9984), 2255–2263. https://doi.org/10.1016/S0140-6736(15)60461-5 6. US POINTER Trial (2024). JAMA. https://jamanetwork.com/journals/jama/fullarticle/2837046 7. Alzheimer's Association. US POINTER Study Results. https://www.alz.org/us-pointer/study-results 8. Livingston G et al. (2024). Dementia prevention, intervention, and care: 2024 Lancet Commission update. The Lancet. https://doi.org/10.1016/S0140-6736(24)01235-4 9. Ornish D et al. Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer's disease: a randomized, controlled clinical trial. Alzheimers Res Ther. 2024 Jun 7; RESOURCES: Book a FREE Discovery Call with AmyDownload After Mom’s Alzheimer’s Diagnosis: The First 8 Things to Know and learn how to support her with more calm, clarity, and confidence.Download the RESTORED Protocol: Eight Essential Protective Factors to Build an Alzheimer's-Resistant BrainSchedule your Breakthrough Roadmap session with AmyFollow Amy on Instagram @amylangcoaching  and on Facebook @amylangcoachingSubscribe to Amy's YouTube channel @happyandhealthywithamy

    38 min
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5
out of 5
20 Ratings

About

Do you want to protect your brain from Alzheimer's disease so you can be sharp and stay sharp for life? This podcast is for you.Your host, Amy Lang, master certified health coach and founder of Moxie Club will be sharing with you the lessons learned and insights gained from 20+ years as a health club owner and Alzheimer's prevention coach.For more information, visit www.moxie-club.com

Information

  • Creator
    Amy Lang
  • Years Active
    2020 - 2026
  • Episodes
    343
  • Rating
    Clean
  • Copyright
    © 2026 Happy & Healthy with Amy
  • Show Website
    Happy & Healthy with Amy