Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition

Sarah Ann Macklin
  • 4.7 (31)
  • ALTERNATIVE HEALTH
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Health shouldn’t feel this hard. I’ve lived it, studied it, and now I’m here to help make it make sense. A smarter, more human way to live well. Subscribe now, and start living well, for real. Instagram: @sarahannmacklin Newsletter: https://substack.com/@sarahannmacklin Website: sarahannmacklin.com #LiveWellBeWell

  1. This One Gut Microbe Could Decide If Cancer Treatment Works | William Li

    2D AGO

    This One Gut Microbe Could Decide If Cancer Treatment Works | William Li

    Watch the FULL podcast here: https://youtu.be/yZDzsfNjG_M Curious what Akkermansia actually does for your health? It’s discussed here as a keystone gut microbe linked to improved insulin sensitivity, lower A1C in clinical studies, GLP-1 release and healthier blood vessels, with associations to cancer immunotherapy response. This clip explores the gut brain circulation connection, how metabolism and energy relate to this microbe, and why people considering immunotherapy might also focus on gut health. We also touch on the importance of discussing immunotherapy with an oncologist and staying within medical advice boundaries. *** This episode is sponsored by: NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell *** The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/ *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

    10 min
  2. Why Compatibility is Overrated: Alain de Botton’s Guide to Relationships That Last

    4D AGO

    Why Compatibility is Overrated: Alain de Botton’s Guide to Relationships That Last

    We spend so much of our lives trying to be impressive. We polish our edges and hide our cracks because we’re terrified that being "real" means being weak. But what if the very things we are hiding are actually the only bridges to real connection? It is a scary thought, but one that completely changes how we show up in the world. Here’s what we explore together: - Why being "invulnerable" is sometimes just as important as being open and how to know the difference. - How accepting your own foolishness can actually make you invincible to humiliation. - Why we feel "boring" with some people and alive with others and why it is not your fault. - How to use curiosity to metabolize pain and crisis into understanding. - Why following your "gut" in love can sometimes lead you straight into disaster. - Why the truth sometimes needs to be delivered in "small pieces" to be heard. - Why a functioning relationship is the most difficult achievement of a human life. - How to find a path that fits your unique nature in a world that wants you to conform. Love, Sarah Ann 💛 *** This episode is sponsored by: NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today 15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex. Learn from world-class sex therapists and relationship experts with courses tailored to your needs. 15% off with code LiveWell15 at mymojo.com/livewellbewell *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/ *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/ 📹 Subscribe:http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast 💌 Newsletter: https://sarahmacklin.substack.com/ *** If You Enjoyed This Episode, You Might Also Like: The 7 Pillars to Finding Genuine Love Beyond Dating Apps | Francesca Hogihttps://youtu.be/aGqlB61ldoA *** Sign up to Sarah’s Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/ *** Highlights 00:00 Intro 02:03 The Vulnerability Paradox: When to Put Your Wall Up 05:26 Why You Should Embrace Being an “Idiot” & Letting Go of Shame 10:22 Mastering Open Communication in Any Relationship 15:36 The Hard Truth About Modern Relationship Challenges 26:16 The Best Question to Ask on a First Date 28:40 Heartbreak and Its Aftermath 37:22 Dealing with Criticism & Managing High Sensitivity 41:12 Reconnecting with Our Bodies 47:38 The Importance of Therapy and Self-Awareness 52:26 The Role of Compassion in Psychotherapy 57:53 Why We Run from Ourselves 01:05:11 Friendship and Emotional Support 01:09:55 The Gift of Vulnerability: Building Deeper Connections 01:14:28 Redefining Success Beyond Money and Status 01:20:17 Communication Secrets for Healthy Long-Term Relationships 01:26:46 Navigating Attachment Styles 01:34:45 The Power of Love and Practice *** Love what you’re hearing? My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.

    1h 41m
  3. How much social connection do we actually need? Loneliness, stress, and midlife health | Anders Hansen

    6D AGO

    How much social connection do we actually need? Loneliness, stress, and midlife health | Anders Hansen

    Watch the FULL podcast here: https://youtu.be/HHvG8HEYdjA Are we built to manage only about 150 meaningful relationships, and what does that mean for our health? It matters because small, real-world connections help lower loneliness-driven stress that can worsen heart disease prognosis and raise some cancer risk. This clip explores the 150-person social limit, why in-person cues beat screens, a call-based study that eased loneliness, concerns about AI companions and hyper-independence, and lessons from hunter-gatherers on movement, sleep, and mood. Together we consider balancing fast tech with our unchanged human needs. *** This episode is sponsored by: NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell *** The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/ *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

    11 min
  4. Can gut bacteria influence brain disease? The microbiome, Parkinson’s and dementia | William Li

    JAN 30

    Can gut bacteria influence brain disease? The microbiome, Parkinson’s and dementia | William Li

    Can specific gut and mouth bacteria influence brain health and conditions like Parkinson's or Alzheimer's? We look at early clinical work on Lactobacillus plantarum PS128 and its potential to slow Parkinson's progression, links between gum disease and dementia, and how Lactobacillus reuteri may stimulate oxytocin. This clip explores the gut-brain and oral-brain connections, the idea of a brain microbiome, and emerging views on brain regeneration and healthy aging. *** This episode is sponsored by: NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell *** The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/ *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

    7 min
  5. Why Women Feel Like TWO DIFFERENT PEOPLE Every Month (The Science of Hormones) | Dr. Sarah Hill

    JAN 28

    Why Women Feel Like TWO DIFFERENT PEOPLE Every Month (The Science of Hormones) | Dr. Sarah Hill

    Ever feel like you’re waking up as two different people depending on the week of the month? One week you’re taking on the world with total confidence, and the next, you’re second-guessing every decision you’ve ever made. It turns out, that isn’t just "you being emotional", it’s actually a sign of your brain responding to a very specific biological rhythm. This week on Live Well Be Well, I’m sitting down with the brilliant Dr. Sarah Hill. She’s an evolutionary psychologist and the author of This Is Your Brain on Birth Control and The Period Brain. Sarah has this incredible way of explaining how our hormones like estrogen, progesterone, and testosterone, aren’t just about reproduction; they are actually "wise advisors" that shape how we think, who we’re attracted to, and how we show up in our work and relationships. Here’s what we explore together: - Your Hormones as Information: How these biological signals act as internal guides for your behavior and motivation. - The "Two Advisors" Theory: Why feeling different across your cycle actually makes you a better, more well-rounded decision-maker. - The Power of Progesterone: Why this often-ignored hormone is actually a neuroprotective "superpower" that helps your brain slow down and recover. - Cycle Variability: Why your "symptoms" can change every month based on everything from sleep to stress. - The Male Perspective: A fascinating look at how men’s testosterone is actually more reactive to the environment (like sports or competition) compared to the predictable cycles of women. - Bridging the Cultural Gap: How to stop overriding your body’s natural cues in a world that expects you to be the same person every single day. Love, Sarah Ann 💛 *** This episode is sponsored by: NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today 15% off with code LWBW15 at https://nowatch.com/ Mojo: the app for expert-led courses in better sex. Learn from world-class sex therapists and relationship experts with courses tailored to your needs. 15% off with code LiveWell15 at mymojo.com/livewellbewell *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/ *** If You Enjoyed This Episode, You Might Also Like: Women's Brain Health: What Science REALLY Says About Hormones, PMS & Menopause | Dr Sarah McKay https://youtu.be/aKnS1McNVm8?list=PLfXKbjBGaUhb7iE0BaE2PZINeLZ3Ybb0M *** Highlights Intro (00:00:00) The Wisdom of the Menstrual Cycle (00:01:55) The Luteal Phase: The Dark Side of the Cycle (00:04:42) Men's Hormones vs. Women's Hormones (00:11:46) The Impact of Hormones on Behavior (00:17:37) Tracking Your Cycle for Better Understanding (00:23:25) PMS: Understanding and Reframing (00:29:49) Evolutionary Perspectives on Attraction (00:36:38) Research on Birth Control and Relationship Satisfaction (00:41:29) Scent and Attraction (01:01:00) Sexual Orientation and Hormonal Influence (01:07:51) Menopause and Attraction (01:11:02) Communication and Understanding in Relationships (01:19:03) The Importance of Recognizing Biological Differences (01:28:35)

    1h 35m
  6. Is Your Phone Killing Your Creativity? 3 Ways to Boost Brain Health | Tj Power

    JAN 26

    Is Your Phone Killing Your Creativity? 3 Ways to Boost Brain Health | Tj Power

    Can boredom and daydreaming actually boost creativity and calm? Here, I’m discussing how a solo writing sprint in nature left my HRV higher and my mind clearer, then we examine the default mode and executive networks, task switching, and screen-free habits. This clip explores the Meals, Bedroom, Bathroom rule for no phones, the value of nature time, and reframing boredom as daydreaming to restore the brain. We talk practical steps for dopamine-heavy habits, why reflection improves decisions, and how daydreaming can spark ideas and support mental health. Watch the FULL podcast here: https://youtu.be/ZoyEJ0WD99g *** This episode is sponsored by: NOWATCH: Health tracking reimagined Know your body, trust yourself.15% off with code LWBW15 at nowatch.com *** The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/ *** Let’s be friends!📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah🐦 Twitter: https://x.com/SarahAnnMacklin📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

    7 min
  7. Longevity Doctor: Alzheimer’s Is Preventable If You Do These 5 Things Early | Dr Darshan Shah

    JAN 22

    Longevity Doctor: Alzheimer’s Is Preventable If You Do These 5 Things Early | Dr Darshan Shah

    Watch the FULL podcast here: https://youtu.be/qHFymGgsYyE Worried about Alzheimer’s and what you can do now? You’ll hear practical, testable steps to lower risk by targeting metabolism, inflammation and toxins, plus daily habits for brain rest and sleep. This clip explores the idea that Alzheimer’s can have different drivers, the importance of early testing (continuous glucose monitors, hs-CRP, urine toxin tests), and simple changes like meditation, less phone time, better sleep, air purifiers, filtered water, non-toxic skin products, and eating organic while avoiding ultra-processed foods. *** This episode is sponsored by: NOWATCH: Health tracking reimaginedKnow your body, trust yourself.15% off with code LWBW15 at nowatch.com *** The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes 👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/ *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/📹 Subscribe: http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast💌 Newsletter: https://sarahmacklin.substack.com/

    4 min
  8. We Weren't Designed to be Happy: The Scientific Reason You Feel "Off" | Anders Hansen

    JAN 21

    We Weren't Designed to be Happy: The Scientific Reason You Feel "Off" | Anders Hansen

    This week on Live Well Be Well, I’m joined by Dr Anders Hansen, psychiatrist, neuroscientist, and bestselling author of The Real Happy Pill and Brain Blues, to explore how modern life is reshaping our mental health, focus, and emotional resilience. In this conversation, Anders explains why anxiety, low mood, and restlessness are not failures of the mind, but evolutionary responses that no longer fit our current environment. We discuss how movement, boredom, attention, and social connection shape brain chemistry, and why understanding our evolutionary wiring can help us respond to stress with more compassion and clarity. Here’s What We Dive Into: - Why the human brain evolved for survival, not constant happiness or comfort. - How modern environments amplify anxiety, low mood, and attention problems. - Why physical movement is one of the most effective interventions for mental health. - How boredom and mental rest support creativity, emotional regulation, and focus. - What social connection does to the brain, and why isolation increases psychological distress. - How dopamine, serotonin, and stress hormones respond to modern stimulation. - Why chasing happiness can backfire, and what a healthier goal looks like. - How understanding evolution helps reduce shame around mental health struggles. Love, Sarah Ann 💛 *** This episode is sponsored by: NOWATCH: The compassionate health tracker Connecting body and mind with unique stress recovery insights so you can live fully today 15% off with code LWBW15 at https://nowatch.com/   *** The Great British Veg Out How to support your gut, energy, and hormones by eating more — not less. 👉 https://sarahmacklin.substack.com/p/the-great-british-veg-out Reset Your Health If your body feels off after stress, travel, or burnout — this is where to start. 👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days 👉 Practical beats perfect. Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks. https://open.substack.com/pub/sarahmacklin/p/download-your-free-5-recipes-to-relieve 👉 If this resonates, you can join the thousands who read The Compassionate Cure each week. https://sarahmacklin.substack.com/What if many of the mental health struggles we face today are not signs that something is wrong with us, but signals from a brain designed for a very different world? *** Let’s be friends! 📷 Instagram: https://www.instagram.com/sarahannmacklin/ 📹 Subscribe:http://www.youtube.com/@livewellbewellsarah 🐦 Twitter: https://x.com/SarahAnnMacklin 📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast *** If You Enjoyed This Episode, You Might Also Like: The Uncomfortable Truth About Why We Can't Commit | Mo Gawdat https://youtu.be/2WeffWLvdbo *** Sign up to Sarah’s Compassionate Cure newsletter: Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/ *** Why modern life feels mentally overwhelming (00:00:00) The evolutionary purpose of anxiety and low mood (00:03:40) Why the brain struggles with constant comfort (00:08:20) Movement and its impact on brain chemistry (00:12:55) Why physical activity reduces anxiety and depression (00:18:30) Boredom, focus, and mental recovery (00:24:10) Social connection and the brain’s safety signals (00:30:05) Dopamine, stimulation, and emotional balance (00:36:40) Why happiness is a poor long term goal (00:42:15) Reducing shame through evolutionary understanding (00:48:30) Practical ways to support everyday mental wellbeing (00:54:10) The Impact of Social Media on Mental Health (00:55:31) The Science of Happiness (01:09:00) Curiosity: The Engine of Growth (01:17:57) *** Love what you’re hearing? My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.

    1h 21m
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4.7
out of 5
31 Ratings

About

Health shouldn’t feel this hard. I’ve lived it, studied it, and now I’m here to help make it make sense. A smarter, more human way to live well. Subscribe now, and start living well, for real. Instagram: @sarahannmacklin Newsletter: https://substack.com/@sarahannmacklin Website: sarahannmacklin.com #LiveWellBeWell

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