As we continue on in our mini series on Immunizations Updates, we are joined by pediatric nurse practitioner Dr. Maddie Manfredi to explore the growing challenge of vaccine hesitancy. Together we will review the profound public health impact of immunizations, define vaccine hesitancy as a spectrum of decision-making rather than simple refusal, and discuss its implications for herd immunity and pediatric outcomes. Dr. Manfredi shares findings from her DNP project, including the use of a novel Caregiver Vaccine Readiness Survey to proactively identify concerns and guide more tailored, patient-centered conversations using motivational interviewing. We’ll highlight the critical role of provider communication in building trust, addressing caregiver concerns, and improving vaccine acceptance, with promising results shared from a DNP project on MMR vaccine acceptance. The episode underscores that how we communicate matters just as much as what we say and invites listeners to rethink traditional approaches in today’s complex sociopolitical landscape. Stay tuned for the next episode, where Dr. Carson and Dr. Manfredi model motivational interviewing strategies through case-based role play. Website: www.thepedsnp.com Contact: thepedsnp@gmail.com Instagram: @thepedsnppodcast AACN Essentials Mapping (Domain. sub-competency): 1.1f, 1.2g 2.2c, 2.2f, 2.3b, 2.4e 3.1a, 3.2b, 3.3d 4.1a, 4.1d, 4.2c 5.1b, 5.2a, 5.3c 6.2b, 6.3a 7.1c, 7.2d 8.2c, 8.3d 9.1a, 9.2f, 9.3c 10.2a, 10.2d, 10.3b References: Bernstein, T. A., Broome, M., Millman, J., Epstein, J., & Derouin, A. (2022). Promoting strategies to increase HPV vaccination in the pediatric primary care setting. Journal of Pediatric Health Care, 36(2), e36–e41. https://doi.org/10.1016/j.pedhc.2021.10.009 Bullen, M., Heriot, G.S., & Jamrozik, E. (2023). Herd immunity, vaccination and moral obligation. 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