The Clinical Research Podcast

Research & Innovation
The Clinical Research Podcast

Getting to the heart of clinical research through the views of world-leading researchers, scientists and academics involved in answering the big questions about our health. From experimental medicine through to understanding common illnesses like asthma and arthritis, we discuss the latest research, what it means for our health and what scientific discoveries are next. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk.

  1. NOV 12

    Explainer - how you can help research stem cell therapy for blood cancer

    An interview with Dr Chloe Anthias, medical director of the new Cell Collection Centre has just opened by Anthony Nolan charity as part of our NIHR Nottingham Clinical Research Facility. Links a little while ago I talked to Prof Mark Bishton, who’s an oncologist at the hospital about stem cell research. Listen here NIHR Nottingham Clinical Research Facility To find out more about the Anthony Nolan Cell Collection Centre, to donate to Anthony Nolan or to find out how to join the stem cell register, visit: www.anthonynolan.org This Podcast is brought to you by the NIHR Nottingham Clinical Research Facility. Follow us on @NottmCRF, or email Nottingham research. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

    15 min

  2. SEP 27

    Using Nanopore sequencing to diagnose brain tumors

    This bulletin intro was brought you by Harriet Anderson from Research and Innovation Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. Tags: #SAPhEStudy, #Nanopore #SequencerDevice, #Tech, #RoundTableTalks, #PRES #BrainTumor Links Nanopore - https://nottinghamcrf.nihr.ac.uk/about/news/nottingham-leads-the-way-dna-sequencing-technology-could-transform-brain-tumour-diagnosis Patient transfers - nuhnt.GetInvolved@nhs.net Loughborough University round-table talks about dementia care and research - Neil.chadborn@nottingham.ac.uk. R&I Clinical support department showcase - i.antonopoulou@nhs.net Participant research experience survey - https://sites.google.com/nihr.ac.uk/crneastmidspres/survey SAPhE study - SAPhEstudy@nuh.nhs.uk This Podcast is brought to you by the ⁠Research & Innovation team at Nottingham University Hospitals NHS Trust⁠. Follow us on ⁠@ResearchNUH⁠ and ⁠@NottmBRC⁠, or email ⁠R&Icomms@nuh.nhs.uk⁠. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

    7 min

  3. AUG 6

    Explainer - how does asthma work?

    Asthma is one of the most common conditions - there are 8 million of us in the UK who suffer from it.  t can range from the needing a quick puff on your inhaler if you exercise and there’s a lot of pollen about it, to serious, fatal attacks, there’s still a lot we don’t know. That’s what this interview with our respiratory physician Matthew Martin is all about. One of the things we’re not sure about is to do with how people with inhalers use them - short version, we might doing it all wrong, then again we might not, this is research after all - and that’s what  the second bit of the interview you’re about to hear covers. More on the APEX trial: https://nottinghambrc.nihr.ac.uk/research/respiratory/airway-disease-theme

    10 min

  4. JUL 18

    Make your contribution to health research

    This bulletin intro was brought to you by Ian Kingsbury from East Genomics Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at ⁠R&Icomms@nuh.nhs.uk⁠. #BioResource, #GLADstudy, #NIHR, #Chest drains, #PneumocystisPneumonia, #NottinghamUniversityHospitals Links East Genomics – https://www.eastgenomics.nhs.uk/ Join the world's largest study of anxiety & depression - https://gladstudy.org.uk/ PCP – If you are interested in contributing to the development of this research proposal, please contact Vikki Flemming, Consultant Clinical Scientist, Clinical Microbiology, vicki.fleming@nuh.nhs.uk  Chest drain - So If you, or someone you care for, has had a chest drain fitted as part of their treatment, please email: GetInvolved@nuh.nhs.uk BioResource – bioresource.nihr.ac.uk or Joanne.Llewellyn@nuh.nhs.uk This Podcast is brought to you by the ⁠Research & Innovation team at Nottingham University Hospitals NHS Trust⁠. Follow us on ⁠@ResearchNUH⁠ and ⁠@NottmBRC⁠, or email ⁠R&Icomms@nuh.nhs.uk⁠. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

    8 min

  5. JUL 9

    Explainer - AHP and physio led researcher

    One of the fundamentals of clinical research is the ‘blind’ bit of the double-blind placebo controlled trial. If neither the researcher nor the participant know whether they’re getting placebo or the drug, it removes the chances that they’re unconsciously  responding in the way they think they should.  The placebo effect can account for up to 30% of a difference, so it has to be dealt with. But if you’re trialling a therapy where the patient will know what’s going on - like exercise for rehab, for example - it can’t be blind. So how do you get round that? We spoke to clinical research  physiotherapist Paul Matthews about the challenges he faced when he was studying exercise as part of rehab for broken ankles. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

    8 min

  6. MAY 9

    Bulletin 11 - mental health research, Nottingham babies, walking for your liver, and walking for leukaemia

    The intro this week was from Harriet Anderson, who works in the Research and Innovation team at Nottingham University Hospitals NHS Trust. Keep listening for more team members introducing other episodes. If you're a clinical researcher at NUH or the University of Nottingham and want to be voice of the podcast contact us at R&Icomms@nuh.nhs.uk. Links Mental health citizen science - www.gladstudy.co.uk Participant in Research Experience Survey - The results for NUH: https://www.nuh.nhs.uk/ri-feedback, and for people in the East Midlands: https://sites.google.com/nihr.ac.uk/crneastmidspres/survey NHS East Genomics - https://www.eastgenomics.nhs.uk/for-healthcare-professionals/genomic-tests/ Liver walks: email Abhishek Sheth at nuhtnt.nottinghamhepatology@nhs.net LifeArc Centre for Rare Respiratory Diseases Willow Tranter appeal - https://www.justgiving.com/page/willowsjourneywithall and Cure Leukaemia https://www.cureleukaemia.co.uk/ Babi study - https://www.babinetwork.co.uk/ This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts or Spotify especially. It's For Science.

    8 min

  7. MAY 2

    Nottingham cancer research is in the top two

    You’d think that clinical researchers would welcome surprises - but they don’t. Even if the results are new and groundbreaking, they want their trials and studies to run in a predictable, controlled way,. And that ability to deliver a total lack of surprise is one of the reasons that cancer research at Nottingham University Hospitals NHS Trust has made it into the top flight in the UK working with major pharmaceutical companies.  As well as clinical and scientific excellence, it’s about building up relationships with our partners so that we know we can deliver on recruiting patients, managing the pharmacy needs, and study set up.  The focus is particularly on chemo-free approach to lymphoma treatment, immunotherapy such as CAR T therapy, bispecific antibodies and using data analysis to target treatments. I talked to Professor Mark Bishton, who’s a consultant haemotologist and the divisional co-lead for research and innovation into cancer and associated. As well as his own research, he’s responsible for delivering the trust’s studies in the specialty. More information at https://www.nuh.nhs.uk/research-in-cancer This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk. If you haven't already, please subscribe to the podcast where-ever you get your podcasts, and like/review us on Apple Podcasts especially. It's For Science.

    15 min

  8. APR 25

    Working with Umecrime Cognition on a treatment for Primary Biliary Cholangitis

    Staff at the NIHR Nottingham Clinical Research Facility talk about the UCAB trial. The facility worked with Swedish pharmaceutical Umecrime Cognition to study using a new molecule as a treatment for Primary Biliary Cholangitis (PBC) for patients with severe symptoms of fatigue and cognitive impairment. Quick takeaways -      • one of only two UK locations for first stage drug trial     • kept to tight, complex timelines     • exceeded recruitment targets by building on existing relationships     • patients praised care and treatment The NIHR Nottingham Clinical Research Facility (CRF)  was one of just two centres worldwide – and the only UK facility – to conduct the first part of a clinical study. We were picked because of our expertise in liver disease. We hosted five patients on a purpose-built inpatient ward within the CRF, to confirm the correct dose of the molecule. During their seven-day stay, our team of research nurses and physicians assessed and cared for the patients around the clock. Nottingham CRF has 18 adult and five paediatric inpatient beds dedicated for research, alongside our dedicated outpatient and specialist clinics. In total, there is over 3,400m² of clinical space at our CRF. The PBC study was a randomised, double-blinded and placebo controlled two-part study to evaluate the pharmacokinetics, safety and tolerability, and preliminary efficacy of two dose levels of the new drug. There’s more about it at https://nottinghamcrf.nihr.ac.uk/facilities/case-studies Follow us on Twitter: @NottmBRC Follow us on Instagram: @NottmHealthScience Follow us on Facebook: https://www.facebook.com/ResearchNottingham Watch a video explainer about clinical trials: https://youtu.be/SWS4FCSMWAQ  Read more at https://www.nottinghamresearch.org/get-involved and https://www.nuh.nhs.uk/take-part-in-a-trial and https://www.nuh.nhs.uk/researchvolunteers Email us at  getinvolved@nuh.nhs.uk

    8 min
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About

Getting to the heart of clinical research through the views of world-leading researchers, scientists and academics involved in answering the big questions about our health. From experimental medicine through to understanding common illnesses like asthma and arthritis, we discuss the latest research, what it means for our health and what scientific discoveries are next. This Podcast is brought to you by the Research & Innovation team at Nottingham University Hospitals NHS Trust. Follow us on @ResearchNUH and @NottmBRC, or email R&Icomms@nuh.nhs.uk.

Information

  • Creator
    Research & Innovation
  • Years Active
    2021 - 2024
  • Episodes
    69
  • Rating
    Clean
  • Copyright
    © Research & Innovation
  • Show Website
    The Clinical Research Podcast

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