Proactive - Interviews for investors

Proactive

Welcome to the Proactive podcast channel – the destination for breaking news on growth companies and up to the minute market coverage. Here we plug you into what’s new and exciting in the world of business.

  1. 18h ago

    Atossa Therapeutics highlights Endoxifen progress as potential Breast Cancer treatment

    Atossa Therapeutics CEO Steven Quayjoined Steve Darling from Proactive to discuss the continued advancement of the company’s lead investigational therapy, (Z)-Endoxifen, and its potential applications across multiple breast cancer indications as well as certain rare diseases. The discussion highlighted the scientific foundation of the program, recent clinical data presentations, and key milestones expected in the months ahead. Quay explained that Atossa Therapeutics was founded with a clear mission focused on improving the prevention and treatment of breast cancer. Central to that strategy is the development of (Z)-Endoxifen, a therapy derived from decades of clinical experience and scientific understanding surrounding tamoxifen, one of the most widely prescribed treatments for hormone receptor-positive breast cancer. While tamoxifen has been a standard therapy for many years, its effectiveness depends on a patient’s ability to metabolize the drug into its active form, Endoxifen. Quay noted that this process can vary significantly between individuals due to genetic differences and metabolic factors. Atossa’s approach is to administer Endoxifen directly, potentially bypassing those limitations and providing more consistent therapeutic exposure across patients. According to Quay, clinical studies conducted to date have demonstrated encouraging signs of efficacy while maintaining what he described as a notably clean safety profile. The company believes the direct administration approach could offer meaningful advantages in both treatment and prevention settings. The CEO reviewed Atossa’s clinical progress, noting that the company has successfully completed multiple Phase 2 clinical trials evaluating Endoxifen in various breast cancer settings. These studies have generated data supporting the continued advancement of the program and helping to define potential pathways toward later-stage development. The findings presented at ASCO generated considerable interest, particularly data suggesting that Endoxifen may remain active in breast cancers that have developed mutations commonly associated with resistance to endocrine therapies. Resistance to hormonal treatments remains a significant challenge in breast cancer management, and the possibility of maintaining therapeutic activity in resistant tumors could represent an important clinical opportunity. Quay noted that feedback from oncologists, researchers, and industry participants at ASCO was highly encouraging, particularly regarding the potential implications of the resistance-related findings. Management believes these observations could help differentiate Endoxifen from existing treatment options and support future development strategies. Looking ahead, Atossa plans to consolidate results from multiple ongoing and completed clinical programs to build a comprehensive dataset supporting future regulatory discussions. The company intends to engage with regulatory authorities and potential pharmaceutical partners as it evaluates the most effective path toward Phase 3 clinical development and eventual commercialization. #proactiveinvestors #nasdaq #atos #BreastCancer #Endoxifen #Biotech #Oncology #ClinicalTrials #CancerResearch #ASCO #DrugDevelopment #HealthcareInnovation

    6 min
  2. 19h ago

    Miivo completes Tandem acquisition to strengthen and align growth strategy

    Miivo Holdings CEO Alex Damouni joined Steve Darling from Proactive to discuss the successful completion of the company’s previously announced acquisition of Tandem Partners, a Dubai-based advisory and operational management firm that has played a significant role in Miivo’s development since its inception. Under the terms of the transaction, Miivo acquired all of the issued and outstanding common shares of Tandem from its shareholders, formally bringing the business and its leadership team fully into the company. Damouni described the acquisition as a natural progression of a relationship that has been deeply integrated into Miivo’s operations from the very beginning. According to Damouni, Tandem has been a key strategic partner throughout Miivo’s growth journey, providing critical executive leadership and operational support through a longstanding contractual arrangement. Under that relationship, Tandem supplied CEO and CFO services to the company while also contributing significantly to the development of Miivo’s flagship AI CFO platform. The acquisition effectively formalizes an existing partnership that has already demonstrated its value through the creation and expansion of Miivo’s AI-driven financial management solutions. Management believes the move will create greater alignment between strategic planning, product development, and execution as the company enters its next phase of growth. Damouni noted that consolidating Tandem’s capabilities within Miivo will strengthen the company’s internal resources and leadership structure while reducing reliance on external service arrangements. By integrating the team directly into the organization, Miivo expects to improve operational efficiency, streamline decision-making processes, and accelerate execution across key business initiatives. The transaction also supports Miivo’s broader strategy of scaling its AI-powered products and services in a rapidly evolving financial technology market. The company believes the combination of Tandem’s advisory expertise and Miivo’s artificial intelligence platform will enhance its ability to deliver innovative solutions designed to help businesses improve financial management, forecasting, reporting, and strategic decision-making. Damouni emphasized that the acquisition represents more than just a corporate transaction—it reflects the evolution of a long-standing partnership that has already helped shape Miivo’s business. With Tandem now fully integrated, the company believes it is better positioned to accelerate product development, enhance execution capabilities, and continue building value through its AI-powered financial technology platform. #proactiveinvestors #miivoholdings #tsxv #mivo #AIForBusiness #Business #ArtificialIntelligence #Fintech #AICFO #BusinessTechnology #DigitalTransformation #FinancialTechnology #CorporateGrowth #AIInnovation #BusinessStrategy

    4 min
  3. 1d ago

    Arizona Gold & Silver launches Silverton drill program targeting Antimony and deeper gold potential

    Arizona Gold and Silver CEO Mike Stark joined Steve Darling from Proactive to announce the start of a 27-hole reverse circulation (RC) drilling program at the company’s Silverton gold-antimony project in Nevada. The campaign is designed to evaluate high-grade antimony mineralization near surface while also advancing the company’s exploration model that suggests the project may overlie a larger concealed gold system at depth. Stark explained that recent geological work has strengthened the company’s belief that the antimony-rich mineralization exposed at surface may represent the upper expression of a deeper carbonate-hosted gold deposit. This interpretation is supported by several geological indicators commonly associated with major gold systems, including widespread silicification, decalcification, jasperoid development, elevated arsenic-antimony-mercury pathfinder geochemistry, anomalous gold values, and a significant conductive magnetotelluric (MT) anomaly identified approximately one kilometre beneath the surface. The new drilling program will focus initially on testing high-grade antimony-bearing quartz-stibnite veins that have been identified through both historic exploration efforts and recent surface sampling programs. Management believes these veins could represent a valuable standalone critical minerals opportunity while also providing important clues about the potential existence of a larger gold-bearing system below. The drilling campaign will comprise 27 reverse circulation holes drilled from 17 separate drill pads strategically positioned across the project area. Most of the holes are expected to range between 30 and 45 metres in depth and are specifically designed to evaluate the continuity, grade, and extent of near-surface antimony mineralization. In addition to the shallow antimony-focused holes, Arizona Gold & Silver plans to drill three deeper holes extending beyond approximately 150 metres. These holes will be cased to allow for potential future diamond drill extensions targeting deeper geophysical and geochemical anomalies interpreted to be prospective for Carlin-type gold mineralization. Stark noted that the project’s timing is particularly favorable given growing U.S. government efforts to secure domestic supplies of critical minerals. The United States Geological Survey (USGS) classifies antimony as a critical mineral because of its importance to national security, defense manufacturing, and strategic supply chains. With global antimony production heavily concentrated outside North America, domestic sources have become increasingly important. #proactiveinvestors #arizonagoldandsilverinc #tsxv #azs #otcqb #azasf #GoldExploration #PhiladelphiaProject #GoldDrilling #BLMPermits #GoldExplorationAZ #MiningInfrastructure #DrillHole156 #JuniorGoldStocks #ArizonaMiningNews #PreciousMetalsInvesting

    3 min
  4. 1d ago

    Chancery Royalty targets fivefold growth as it builds a Gold and Silver royalty portfolio

    Chancery Royalty CEO Jeremy Gray joined Steve Darling from Proactive to discuss the company’s strategy of building a leading precious metals royalty business focused exclusively on gold and silver assets. Backed by a management team with decades of mine-building and operational experience, the company is positioning itself to capitalize on attractive royalty opportunities that may be overlooked by larger competitors in the sector. Gray explained that the leadership team brings an extensive track record of success in the mining industry, having previously helped develop and operate several notable gold companies and projects, including Pilar Gold, Laiva Gold in Finland, Tucano Gold, Great Panther, and Gold Road in Arizona. Having gained firsthand experience creating value through mine development and operations, the team is now applying that expertise to the royalty business model, which offers exposure to production growth while minimizing operational and capital risks. Chancery Royalty currently holds five royalty assets, one of which is already generating revenue through production. The remaining four assets are expected to advance into production over the next 12 to 18 months, creating the potential for a growing stream of royalty income as development milestones are achieved. The company’s investment strategy is focused exclusively on gold and silver royalties, targeting opportunities that offer meaningful gold equivalent ounce growth potential. Gray noted that Chancery seeks assets that may not attract the attention of larger royalty companies but still possess strong fundamentals, development pathways, and the potential to generate significant long-term value. One of the company’s most significant recent transactions was a US$20 million royalty agreement with KEFI Copper and Gold involving a major project in Ethiopia. Gray described the asset as “probably the best undeveloped gold mine in Africa,” highlighting its scale and development potential. The transaction is expected to add approximately 7,000 GEOs to Chancery’s portfolio, representing a substantial increase in future royalty exposure. The KEFI transaction aligns with Chancery’s broader growth objective of expanding its royalty portfolio from approximately 4,000 GEOs today to 20,000 GEOs within the next two years. Management believes achieving this target would significantly increase the company’s revenue potential and establish a stronger foundation for long-term growth. Gray also discussed additional royalty opportunities currently under evaluation. These include recent activity involving Buxton, as well as prospective transactions in key mining jurisdictions such as Timmins, one of Canada’s most prolific gold-producing districts. The company is also reviewing another near-term production royalty opportunity that could further accelerate portfolio growth. To learn more about the company check out https://www.chanceryroyalty.com #proactiveinvestors #ChanceryRoyalty #GoldRoyalties #SilverRoyalties #MiningInvestment #GoldMining #PreciousMetals #RoyaltyCompanies #ResourceInvesting #MiningNews #CSEListing

    4 min

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Welcome to the Proactive podcast channel – the destination for breaking news on growth companies and up to the minute market coverage. Here we plug you into what’s new and exciting in the world of business.

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