AI for Health

Sarah Benamara

We explore different ways in which artificial intelligence brings innovations to the future of healthcare. Produced and hosted by Sarah Benamara.

Episodes

  1. 04/01/2021

    AI for Vaccine Development

    On this episode I discuss the use of AI-based approaches for the development and discovery of effective vaccines. Reverse Vaccinology and Machine Learning AI-based design of multi-epitope vaccines Deep Learning for Cancer Vaccines Black, Steve et al. “Transforming vaccine development.” Seminars in immunology vol. 50 (2020): 101413. doi:10.1016/j.smim.2020.101413 Ong, Edison et al. “COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning.” Frontiers in immunology vol. 11 1581. 3 Jul. 2020, doi:10.3389/fimmu.2020.01581 Tomic, Adriana et al. “SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses.” Journal of immunology (Baltimore, Md. : 1950) vol. 203,3 (2019): 749-759. doi:10.4049/jimmunol.1900033 Moxon, Richard et al. “Editorial: Reverse Vaccinology.” Frontiers in immunology vol. 10 2776. 3 Dec. 2019, doi:10.3389/fimmu.2019.02776 He, Yongqun et al. “Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development.” Journal of biomedicine & biotechnology vol. 2010 (2010): 297505. doi:10.1155/2010/297505 Ong, Edison et al. “Vaxign-ML: supervised machine learning reverse vaccinology model for improved prediction of bacterial protective antigens.” Bioinformatics (Oxford, England) vol. 36,10 (2020): 3185-3191. doi:10.1093/bioinformatics/btaa119 Yang, Brian et al. “Protegen: a web-based protective antigen database and analysis system.” Nucleic acids research vol. 39,Database issue (2011): D1073-8. doi:10.1093/nar/gkq944 Yang, Z., Bogdan, P. & Nazarian, S. An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study. Sci Rep 11, 3238 (2021). https://doi.org/10.1038/s41598-021-81749-9 Tomar, Namrata, and Rajat K De. “Immunoinformatics: an integrated scenario.” Immunology vol. 131,2 (2010): 153-68. doi:10.1111/j.1365-2567.2010.03330.x Keshavarzi Arshadi, Arash et al. “Artificial Intelligence for COVID-19 Drug Discovery and Vaccine Development.” Frontiers in artificial intelligence vol. 3 65. 18 Aug. 2020, doi:10.3389/frai.2020.00065 Wu, Jingcheng et al. “DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity.” Frontiers in immunology vol. 10 2559. 1 Nov. 2019, doi:10.3389/fimmu.2019.02559

  2. 03/21/2021

    AI for Mental Health

    I discuss how AI has the potential to redefine the diagnosis and understanding of mental illnesses. Prediction of mental health disorders in teenagers Helping student's mental health and academic performance Preventing mental health disorders among healthcare workers Examples of AI technologies applied to mental health References: Tate AE, McCabe RC, Larsson H, Lundstrom S, Lichtenstein P, Kuja-Halkola R. Predicting mental health problems in adolescence using machine learning techniques. PLoS One. 2020;15(4):e0230389. Rutter M, Kim-Cohen J, Maughan B. Continuities and discontinuities in psychopathology between childhood and adult life. J Child Psychol Psychiatry. 2006;47(3-4):276-95. Pettersson E, Anckarsater H, Gillberg C, Lichtenstein P. Different neurodevelopmental symptoms have a common genetic etiology. J Child Psychol Psychiatry. 2013;54(12):1356-65. Dwyer DB, Falkai P, Koutsouleris N. Machine Learning Approaches for Clinical Psychology and Psychiatry. Annu Rev Clin Psychol. 2018;14:91-118 Dekker I, De Jong EM, Schippers MC, De Bruijn-Smolders M, Alexiou A, Giesbers B. Optimizing Students' Mental Health and Academic Performance: AI-Enhanced Life Crafting. Front Psychol. 2020;11:1063. Cosic K, Popovic S, Sarlija M, Kesedzic I, Jovanovic T. Artificial intelligence in prediction of mental health disorders induced by the COVID-19 pandemic among health care workers. Croat Med J. 2020;61(3):279-88. Su C, Xu Z, Pathak J, Wang F. Deep learning in mental health outcome research: a scoping review. Transl Psychiatry. 2020;10(1):116.

About

We explore different ways in which artificial intelligence brings innovations to the future of healthcare. Produced and hosted by Sarah Benamara.