Today I’m joined by an incredible guest, Professor John Nolan, a nutritional scientist like me, from Ireland whose work over the past 20 years has explored a fascinating question: Can targeted nutrients help optimize how we see, think, perform, and age? John’s research focuses on specific carotenoids derived from marigolds — lutein, zeaxanthin, and meso-zeaxanthin — and their potential role in supporting vision, brain health, memory, cognitive function, and healthy aging. His work also explores the interaction between targeted micronutrients and omega-3 fatty acids, bringing us closer to the concept of precision nutrition — using specific nutrients strategically based on individual needs and health outcomes. In his recent SNIPE study, John and his team investigated a combination of the triple carotenoid formula with omega-3 fatty acids and found improvements in visual function and performance-related outcomes in precision-sport athletes, including athletes such as baseball players, archers, hunters, and esports competitors — populations where visual performance can be critical. His research has also extended into age-related and neurological conditions. The re-MIND trialexplored the potential effects of targeted carotenoid supplementation in people with Alzheimer’s disease, while the Crest AMD study investigated visual performance in people with early age-related macular degeneration. What makes this conversation particularly meaningful to me is the connection between John’s research and my own work in nutrition research, preventive health, and longevity. My research interests include the relationship between diet quality and disease-related outcomes in endometriosis, while my work through Vici Wellness focuses on nutrition, physical activity, lifestyle medicine, and helping people build healthier lives for the long term. We also explore how this emerging research fits into the broader principles of Blue Zone living and healthy aging. Blue Zone research has emphasized the importance of dietary patterns, movement, social connection, and lifestyle habits in supporting longevity. John’s work adds another fascinating layer to that conversation: how specific nutrients and nutrient combinations may influence function and performance as we age. This episode is about looking beyond simply asking, “Are you eating healthy?” and beginning to ask more nuanced questions about diet quality, nutrient status, individual needs, and precision nutrition. And perhaps most importantly, we discuss why this research matters to everyday people. Many of us have been personally affected by vision loss, cognitive decline, Alzheimer’s disease, or age-related conditions — or participate in activities and sports where visual performance matters. John’s career and research have even inspired a documentary. A Vision for Vision, created by two-time Emmy Award-winning filmmaker Wayne Chesler, explores John’s journey, his research, and the remarkable potential of nature and nutrition. The documentary is scheduled for digital/VOD release beginning November 3. This is a conversation about nutrition, science, performance, brain health, vision, and longevity — and where the future of targeted nutrition may take us. Stay Tuned for Elena’s latest research in nutrition and women’s health Film can be found at @avisionforvision and John at @profjohnnnolan
