ZOE Science & Nutrition

ZOE

The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.

  1. 23h ago

    How to build muscle & stay strong at any age: The surprising links between your gut health, strength training and healthy ageing | Prof Claire Steves & Prof Tim Spector

    How do you build muscle and stay strong as you age? For most of us, muscle loss starts in our 30s. It’s easy to think that you can combat this and stay strong into old age by strength training and eating plenty of protein. Exercise and macros matter, but scientists are uncovering another important piece of the puzzle - a direct connection between your gut health and healthy ageing. It could change how we think about staying strong as we get older.  In today's episode, Professor Claire Steves - a world-leading expert in ageing and health - and Professor Tim Spector explore the gut-muscle axis - how your gut microbiome influences your muscle health. They explain why maximum protein doesn't mean maximum muscle, how gut bacteria ‘talk’ to muscle tissue, and why an unhealthy gut can make muscles resistant to growth.  For listeners looking for simple ways to support their muscles today, this episode includes practical advice you can easily fit into your routine. Claire and Tim share quick daily habits and explain how to get your protein from diverse plant sources.  Could changing what you feed your gut microbes today be the key to keeping your body strong for decades to come? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 04:08 Why muscle matters for healthy aging, not just the gym 06:37 The hidden organ: how your muscles talk to your body 10:35 Why it gets harder to keep muscle as you age 11:37 Can you have a 20-year-old's muscles at 70? 13:29 Can muscle loss increase your risk of cancer? 15:51 Why skinny doesn't mean healthy 17:40 What is sarcopenia? 20:52 How 4 days of bed rest can shrink your muscles 23:31 Gut-muscle axis: how gut bacteria talk to your muscles 23:53 Why protein stops working as you age 26:11 Can improving your gut health build stronger muscles? 28:57 Can strength training change your gut microbiome? 30:57 Can the Mediterranean diet make your legs stronger? 34:01 The diet trial that improved muscle and bones, no gym 34:55 Is there a magic gut bug for building muscle? 39:38 Intermittent fasting: should you exercise before breakfast? 44:43 Can too much protein weaken your muscles? 46:32 How much protein do you really need per day? 49:20 The best protein foods to feed your gut and muscles 52:26 Carnivore diet: what meat and shakes do to your gut 53:46 Strength training, cardio or balance: what do you need? 56:04 The easy 2-minute toothbrush habit for better muscle health 57:21 Key takeaways: muscles, microbes, and the protein myth26:11 Can improving your gut health build stronger muscles? 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Master Cyclist Study, King’s College London (2018) Physical Activity and Reduced Cancer Risk, Nat Rev Cancer (2008) Bed Rest and Muscle Loss, Diabetes (2016) Microbiome Interventions and Inflammation, Cureus (2025) The Gut Microbiome and Muscle Strength, BMC Geriatr (2021) Resistance Training Reshapes the Gut Microbiome, Sports Med Open (2026) The Mediterranean Diet and Muscle Strength, Physiotherapy Theory and Practice (2025) Short-Chain Fatty Acids and Muscle Mass, J Cachexia Sarcopenia Muscle (2024) Mitochondrial Properties in Skeletal Muscle Fiber⁠, Cells (2023) Episode transcripts are available here.

  2. 2d ago

    Most replayed moment: How to stop fighting your body clock | Prof. Debra Skene

    Every one of us runs on a biological rhythm - a finely tuned system that controls when we feel alert, when we feel tired, and even how we process food. But here’s the problem: modern life doesn’t always respect this rhythm. Late nights, early alarms, and irregular meals put many of us out of sync with our own biology. I’m joined by Professor Debra Skene to explain why this mismatch matters, and how you can transform your health by aligning your lifestyle with your internal ticker. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

  3. Oct 1

    How to eat to lower inflammation - the top 5 foods to boost energy, stop pain, and to live longer | Prof Luke O’Neill

    Most of us think of inflammation when an ankle swells or a cut turns red. It’s our body’s immune system, and without it, we couldn't fight infections or repair injuries.  But when it stays switched on, this chronic inflammation can drain your energy, can affect your health over the years, and even lead to heart disease. Eventually, 1 in 3 of us will develop an inflammatory disease. In today's episode, Professor Luke O'Neill - one of the world's top 1% immunologists - explains why that matters and what you can do about it. He explores how everyday foods can push inflammation up, or help calm it. He also explains why balance matters more than banning foods like sugar, red meat, gluten, and dairy. As for your gut, you’ll learn how anti-inflammatory foods like plants, fibre, and a healthy microbiome can help keep inflammation down.  By the end of the episode, you'll know how to eat, rest, and enjoy life in ways that can keep inflammation in check.  Could the way you eat help your body's healer do its job without going into overdrive?  🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 04:14 Why 1 in 3 people will get an inflammatory disease 06:49 When inflammation turns from healing to harmful 10:23 Why does your immune system now damage your heart and brain? 13:46 Why does chronic inflammation make you so tired? 15:35 The link between depression and inflammation explained 18:10 Does inflammation speed up ageing? 19:56 Testing for chronic inflammation - what CRP tells you 23:01 Does belly fat cause inflammation? What Ozempic reveals 25:46 Does your gut microbiome affect inflammation? 28:04 Are ultra-processed foods inflammatory? Sugar and fat explained 30:18 Does sugar make inflammation worse?  33:15 Insulin resistance and inflammation 35:07 Fructose: fruit vs processed food 39:35 Is red meat inflammatory? How much is too much 41:52 Does gluten cause inflammation?  44:29 Does dairy cause inflammation?  46:13 Seed oils and inflammation  46:40 The anti-inflammatory diet 49:38 Anti-inflammatory plants: how willow bark led to aspirin 51:32 Do polyphenols fight inflammation?  53:44 Do anti-inflammatory supplements work? Are they worth it? 54:34 How to reduce inflammation today: why morning sunshine matters 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode Daily 30: Does it work? The Mediterranean diet and CRP levels, Nutrients (2018) Metabolic Reprogramming in Stromal and Immune Cells in Rheumatoid Arthritis and Osteoarthritis, European Journal of Immunology, (2025)Episode transcripts are available here.

  4. Sep 29

    Most replayed moment: The hidden dangers of hearing loss | Prof. Marcelo Rivolta

    The world around us is louder than ever. From booming speakers to roaring traffic, our ears can take quite a beating. But have you ever stopped to consider the long-term impact of all this noise? Because hearing loss isn’t just about your ears. Emerging research suggests it could also affect your brain health in surprising ways. I’m joined by Professor Marcelo Rivolta to explore how noise exposure can cause lasting damage. He shares the early warning signs to look out for, what to do if your hearing begins to decline, and simple steps you can take to protect these vital organs on the side of your head. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

  5. Sep 24

    Inside Tim Spector’s weekly food shop - 6 grocery rules to lower your blood pressure, cholesterol, and heart disease risk | Prof Tim Spector & Prof Sarah Berry

    Supermarket shelves are full of foods promising to be healthy: high-protein, low-fat, gluten-free, sugar-free. How do you know what's true?  Today, Professors Tim Spector and Sarah Berry, world-leading experts in nutrition and diet, share the six rules they use for their own weekly grocery shopping. They cover which food labels are worth trusting and which are just marketing scams, how to make snacking a part of a healthy diet, and why your daily staples, like bread, matter more than the occasional treat. By the end of this episode, you'll know exactly what to reach for on your next shop, and what to leave on the shelf. How many "healthy" scams are sitting in your basket? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 03:20 Why supermarkets stock 30,000 products (and why that's bad for you) 08:10 Is low-fat food actually healthy? A nutrition scientist explains 11:39 Why 'sugar-free' labels should make you suspicious 14:48 Why this professor avoids gluten-free food (unless you need it) 16:40 The protein label that tricks 70% of shoppers into buying junk food 19:27 How a cheap dairy waste product got rebranded as a health food 21:59 How many ingredients are really in a bag of Pringles? 24:37 The 30-second trick to spot ultra-processed food at the shop 27:33 How to tell a healthy granola from a fake one 29:24 Is cheese actually bad for your heart? Doctors got this wrong 33:37 The snack swap that cut heart disease risk by 30% in a real study 38:36 The 6 everyday foods that matter most for your long-term health 41:08 The simple fiber-to-carb ratio for picking a healthy bread 43:43 The 'unhealthy' breakfast a nutrition scientist admits to craving 46:47 Switching to whole grain could lower your risk of dying early 49:42 The label trick that makes fake kefir look healthy 50:07 What to check on a kombucha label before you buy it 52:51 Why 30 plants a week beats the old '5 a day' rule 53:42 The 'diversity jar' hack for hitting 30 plants a week fast 55:45 The pantry staple that quietly boosts your plant count 57:10 The most underrated vegetable for lowering blood pressure 59:56 The 6 rules two nutrition scientists use to shop for food 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode The effect of snacking on nuts on heart health, The American journal of clinical nutrition (2020) Low fat diets for long-term weight loss, The Lancet (2015) Wholegrain consumption and all cause mortality, BMJ (2016)  ZOE Snacking Study Episode transcripts are available here.

  6. Sep 22

    Most replayed moment: What your wearable is really telling you | Dr Malcolm Finlay

    From smartwatches to fitness trackers, more of us than ever are monitoring our health in real time. With just a glance at our wrist, we can check our step count, sleep quality, heart rate and, more recently, something called HRV. But what do these numbers actually mean? And more importantly, how can we use them to improve our lives? I’m joined by Dr Malcolm Finlay to break down the data behind the devices. He explains how to turn confusing metrics into meaningful action. helping you adjust your training, manage stress, and make smarter decisions for your health. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

  7. Sep 17

    Is your gut the secret to anti-aging? 6 science-backed ways to boost your bone strength, muscle, and balance | Prof Elaine Dennison

    Picture the sound of a bone snapping - the kind of sound that makes you wince - and ask yourself how often you’ve thought about your bone health. Most of us only think about bone density when something breaks. Until then, your bones stay almost invisible, carrying you through every day. In today’s episode, Professor Elaine Dennison, a world-leading expert in bone health, explains why that needs to change, why stronger bones are key to living more healthy years, and why declining bone health isn’t inevitable. Elaine explains why it’s not just about avoiding broken bones, but about learning to understand one of the most important living tissues in your body. By the end of the episode, you’ll know exactly how to protect your bones so they can look after you now and for many years to come. Could your bones be the missing anti-aging link you’ve been missing? 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Build healthy habits. Download the ZOE app today and start your trial for just £2.30 for your first week. 👉 Join ZOE Follow ZOE on Instagram. Timecodes 00:00 Intro 03:05 Are your bones dead tissue? The truth about bone biology 08:08 Peak bone mass: the age your bones stop getting stronger 11:06 What is osteoporosis? The condition you won't feel coming 14:01 Spinal fractures and death risk: what the research shows 15:53 What does osteoporosis do to your bones? The honeycomb explanation 17:46 Fragility fractures: why older adults break bones from a simple fall 20:02 Bone marrow function: what your bones do for your immune system 22:48 The gut-bone axis: how gut health affects bone health 27:01 Does stress affect bone health? The cortisol connection 29:45 Is alcohol good or bad for bone health? The surprising answer 30:16 Does extra weight protect your bones? What the science says 32:13 GLP-1 drugs and bone health: the risk no one's talking about 33:21 Muscle loss and bone density: why they're linked 35:37 DEXA scan: the only way to know your bone density 39:06 Osteoporosis medication: how doctors treat bone loss 40:51 Best exercise for bone density: why walking isn't enough 42:54 How much calcium do you need a day for strong bones? 44:04 Vitamin D and bone health: why you need it to absorb calcium 45:41 Why vitamin D deficiency is common in sunny Australia 47:22 Does HRT protect your bones? The benefits and risks explained 48:31 Do weighted vests improve bone density? What the evidence shows 49:44 How to improve bone health: the first steps to take 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Mentioned in today's episode The effect of Daily30 on Gut Health, Energy Levels, and Hunger in Healthy Adults, Cambridge University Press (2026) Mortality Rate in Patients with Vertebral Compression Fractures, Geriatric orthopaedic surgery & rehabilitation (2023) The Influence of the Mediterranean Diet on Bone Health, Nutrients (2023)  Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

  8. Sep 15

    Most replayed moment: How to build a better breakfast | Prof. Ben Gardner & Tim Spector

    We’ve all heard the saying: Breakfast is the most important meal of the day. And while it may sound like a cliché, there’s some truth to it. Because for many of us, breakfast is the one meal we keep the same - day after day, morning after morning.  This consistency means our breakfast choices have a powerful influence on our long-term health. So, today I’m joined by Tim Spector and behaviour expert Professor Ben Gardner to share practical ways to break out of unhealthy routines and build a breakfast habit that will support you every single morning. 🌱 Try our science-backed and tasty wholefood supplement Daily30 🌿Let your gut microbes snack on the ZOE Gut Health Bar Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati The Appetite Reset by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Good Mood Food (preorder) by Prof. Tim Spector Free resources from ZOE The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra   Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide Have feedback or a topic you'd like us to cover? Let us know here. Episode transcripts are available here.

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About

The world’s top scientists explain the latest health, nutrition, and gut health research and translate it into practical advice to improve your health & weight. Join ZOE Science & Nutrition, on a journey of scientific discovery. Hosted by Jonathan Wolf.

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