The Critical Care Commute Podcast

Critical Care Commute

The Critical Care Commute Podcast is grateful for your ears, insights and feedback. In return its hosts- Peter Brindley and Leon Byker, two ICU doctors in Alberta, Canada- offer up knowledge and debate with some of the most qualified, interesting, enlightened and provocative folks in Critical Care Medicine, and beyond. We strive to keep it practical and concise. Like you, our overriding goal is to get better, do better and feel better.

  1. Antibiotic Stewardship: IV Amoxiclav with Dr George Zhanel

    Apr 17

    Antibiotic Stewardship: IV Amoxiclav with Dr George Zhanel

    In this episode, made possible through an educational grant from Sandoz Canada, Dr. George Zhanel discusses the latest developments in antimicrobial stewardship, focusing on IV Amox Clav, its clinical applications, safety profile, and the Canadian Leadership on Antimicrobial Real-Life Usage Registry (CLEAR). Gain insights into optimizing antibiotic use and future prospects in antimicrobial development. Key Topics: IV Amox Clav clinical applicationsCanadian Leadership on Antimicrobial Usage Registry (CLEAR)Antibiotic stewardship strategiesFuture developments in antimicrobial agents Chapters: 00:00 Introduction and Guest Credibility 01:47 Introduction of Dr. George Zhanel and his background 02:41 The journey into IV Amox Clav and its significance 03:21 Overview of the CLEAR registry and its purpose 06:18 Findings from the CLEAR study on IV Amox Clav usage 07:57 Clinical indications and safety profile of IV Amox Clav 10:58 De-escalation and appropriate use of IV Amox Clav 12:34 Use in bacteremia and various infections 13:35 Side effects and safety data of IV Amox Clav 15:02 Dosing strategies and renal adjustments 17:29 Beta-lactamase inhibitors and future antimicrobial development 20:16 Future prospects for new antibiotics in Canada 23:13 Canadian Antimicrobial Resistance Alliance (CARA) and involvement 25:53 Case examples and clinical decision-making in pneumonia and skin infections 31:09 Closing remarks and appreciation for the audience Resources: Canadian Leadership on Antimicrobial Real-Life Usage Registry (CLEAR) - https://www.clearregistry.ca Canadian Antimicrobial Resistance Alliance (CARA) - https://www.cara.ca Meropenem Vaborbactam - https://www.meropenem.com Ceftazidime-Avibactam - https://www.ceftazidime-avibactam.com Guest Links: LinkedIn - https://www.linkedin.com/in/george-zhanel Twitter - https://twitter.com/GeorgeZhanel

    32 min
  2. Critical Care Workforce: Where We Are, And Where We're Going with Prof. Peter Kruger

    Feb 24

    Critical Care Workforce: Where We Are, And Where We're Going with Prof. Peter Kruger

    In this conversation, Peter Brindley and Leon Byker sit down with Peter Kruger, President of the College of Intensive Care Medicine, to unpack one of the defining issues facing healthcare today: workforce reform. Against the backdrop of national workforce reviews across Australia and New Zealand, the discussion explores the tension between aspiration and reality. Governments want equitable access, rural coverage, sustainable systems, and improved wellbeing for clinicians. Colleges want standards, safety, and meaningful careers. Trainees want jobs. Communities want hospitals. Politicians want solutions. So how do we reconcile all of it? Dr. Kruger reflects on the growing engagement between specialist colleges and government, particularly around workforce maldistribution, rural and regional care, sub-specialization versus generalism, and the moral complexity of relying on internationally trained doctors. The conversation highlights a key truth: intensive care is a hospital-based, system-dependent specialty. You cannot simply “place a doctor” in a community without the supporting infrastructure. The episode also tackles uncomfortable but necessary questions: Can there be a universal standard for ICU access across vastly different hospital settings? Should governments mandate rural placements—or can communities be strengthened from within? What role should nurse practitioners and multidisciplinary teams play? Are we protecting turf, or protecting patients? And how do we better support doctors across the entire career pipeline—from medical student to senior intensivist winding down night shifts? Throughout, the tone is candid but diplomatic. There’s recognition that workforce reform is complex, long-standing, and resistant to simple solutions. Yet there is also optimism: trust, transparency, and genuine partnership between colleges and government may offer a way forward. At its core, this episode is about purpose. The shared mission between clinicians, colleges, and governments is delivering safe, effective care to the community. The challenge lies in doing so while balancing standards, sustainability, and humanity.

    24 min

Ratings & Reviews

4.6
out of 5
7 Ratings

About

The Critical Care Commute Podcast is grateful for your ears, insights and feedback. In return its hosts- Peter Brindley and Leon Byker, two ICU doctors in Alberta, Canada- offer up knowledge and debate with some of the most qualified, interesting, enlightened and provocative folks in Critical Care Medicine, and beyond. We strive to keep it practical and concise. Like you, our overriding goal is to get better, do better and feel better.

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