Myosin.xyz

Myosin.xyz

Myosin.xyz is the ultimate decentralized marketing network, accelerating the onchain revolution to create a more equitable internet. Subscribe to listen to our shows Chain Reactions & Netcetera. Chain Reactions is a weekly livestream where we talk about the latest in blockchain, break down interesting marketing campaigns, and have fun w/ourselves, members, and friends of Myosin. Netcetera is a series where we talk to leaders at the forefront of innovation, whether at traditional brands, web3 or AI companies, to demystify the innovations sharing the new internet.

  1. 20h ago

    Chain Reactions Live #0003: Google's AI Mode Ads Nobody Covered + Agent Orchestration for Growth

    Google quietly shipped four new ad formats inside AI Mode, and almost nobody covered it. We did. Plus: a $13 CPC on ChatGPT ads, and Memrise's growth agent that lives entirely in Slack.CHAPTERS00:00 Cold open03:06 Welcome — Victoria joins, Polina returns04:24 What's on the show today05:30 WATERCOOLER: Sonnet 5's price hike and Fable 5's return07:38 Token-maxing culture and the hidden cost of the price hike10:16 Ford rehires the people it fired — to train the AI12:47 Why the most elementary AI framing gets the most buzz14:27 Benchmarking models on price, speed and quality before you buy15:12 Product Hunt's June: the top tools were integrations, not standalone AI17:30 The core stack nobody has replaced (and why Slack survived)22:14 The vibe-coded app problem: broken back ends, ToS exposure, $20 lessons26:01 Cannes Lions: the agency billing model everyone admits is dead28:02 Creator activations go niche — eyeballs over follower counts28:45 Why Victoria skipped Cannes, and the CEO as the next creator31:04 Celebrity clout vs. an actual event strategy33:40 AI's image rehab in marketing, and the founders paying for their own message36:06 SheaMoisture flipped the creator brief39:21 Why YouTube mid-roll ad reads stopped working40:42 Google's AI Mode ads — the story nobody covered43:03 Four new ad types, and what a business owner is actually signing up for44:43 A $13 CPC on ChatGPT ads46:10 Could ChatGPT just run an affiliate network instead?49:44 MARKDOWN: Lizzie Lawley, Head of Applied AI at Memrise50:20 From pilot, to AI companion platform, to Wombat, to Memrise53:39 The system map: every input feeding the growth machine56:00 Core principles: context first, cheapest capable model, disagreement as a feature56:36 "Months of work in hours" — what it actually saved58:36 The loops: synthesis, experiment shaping, prototyping, build ticket, human gate1:00:41 Live demo: "It's just Slack, baby"1:03:10 How the agent gets fresh context every single night1:06:04 OpenClaw V1, then real engineers rebuilt it1:07:06 The failures: how expensive it got, real quick1:08:32 The model pricing tier system, tier by tier1:11:19 Where the user interviews actually live (it's Google Docs)1:13:59 The bot that spammed banana emojis, and what it taught her1:15:54 Claude Design as a starting point for growth people who can't design1:17:35 Why we skipped Hot Button this week1:18:27 ADAHOLIC: the rules1:20:22 Round 1: Ed Sheeran, a posh restaurant, and way too many forks1:23:33 Round 2: red key, blue key, and a luxury pitch1:26:23 Round 3: "Yo... where's Dukey?"1:29:03 Round 4: the Mother's Day one1:32:26 Round 5: the car ad Arnav paused a second too late1:35:14 Round 6: puffballs, chrome nails and woodworking1:39:07 Round 7: "a better everyday life for the many people"1:40:41 Victoria takes the crown on her first appearance1:41:54 CloseTHIS WEEK'S GUESTLizzie Lawley — Head of Applied AI at Memrise, co-founder of Wombat. She built a platform handling millions of simultaneous AI interactions with cost-efficient model routing, and now runs agent orchestration for Memrise's growth team. Her system pulls from transcripts, app reviews, Zendesk tickets, past experiment synthesis, Athena and BigQuery, and runs a nightly cron job so the agents never work off stale context. Methodology follows Bob Moesta's jobs to be done. The team calls it BYOB — bring your own Bobby.Ads featured in Adaholic this week: Heinz, Kia, Budweiser, Honda, Pinterest, IKEA.

    Chain Reactions Live #0003: Google's AI Mode Ads Nobody Covered + Agent Orchestration for Growth
  2. Aug 3

    Chain Reactions Live #0002: WhatsApp's New CEO, Google's A24 investment, Cursor Acquisition

    Chain Reactions is the live marketing talk show from Myosin — built by operators, for operators — breaking down the marketing happening all around you with people who actually run growth.Today, Arnav is joined by the two OGs of the show, Blake and Polina, for a 90-minute run-through of the stories the Silicon Valley echo chamber is losing its mind over, a live tool teardown, a debate, and a game that exposes how many ads you consume without realizing it.What we get into:- Kunal Shah taking the WhatsApp global CEO seat — CRED, UPI, and whether messaging apps actually become the payment layer in markets like India, China, and parts of Europe- SpaceX's IPO, the 5% float, and xAI/Grok acquiring Cursor for $60B in stock — a customer-and-talent grab more than an IDE play- Why local models became the whole conversation overnight: token economics, Anthropic's pricing shift, and what the Fable/Mythos restrictions mean for anyone building on frontier models- Google's $75M move into A24, AI in filmmaking, and the creative-tooling debate (Tron, Toy Story, and the "press a button to make AI disappear" crowd)- Markdown — Polina walks through the content automation system behind her UFC prediction tool: trusted-source scraping, virality scoring, Telegram alerts, and Fal.ai image generation with a human always in the loop- Hot Button — should performance marketing report to the CFO or the CMO? A "cordial" debate that turns into a real argument about attribution, LTV, and who owns the risk- Adaholic — guess the brand and category from the ad clip. Polina runs away with it, seven wins deep.CHAPTERS00:00 Intro — welcome back, Blake & Polina01:16 Watercooler: Kunal Shah → WhatsApp global CEO (CRED, UPI, WeChat-ification)09:32 SpaceX IPO + xAI/Grok acquires Cursor for $60B20:07 The local models moment, token economics & Anthropic pricing30:19 Google's $75M into A24 + AI in film and creative38:08 Markdown: Polina's UFC content automation teardown54:32 Hot Button: should performance marketing report to CFO or CMO?1:11:16 Adaholic: name that ad#ChainReactions #GrowthMarketing #AIMarketing #GTM #PerformanceMarketing #MarketingPodcast #Myosin #MarketingStrategy #LocalModels #VibeMarketing #CMO #SpaceX #Grok #B2BMarketing #MarketingNews #GrowthMarketing #AIMarketing

    Chain Reactions Live #0002: WhatsApp's New CEO, Google's A24 investment, Cursor Acquisition
  3. Mar 16

    From AI-Wary to AI-Enabled Marketers

    In this episode, we sit down with Jay and Shane, Co-Leads of the AI-Enabled Marketer & Growth Guild at Myosin, to unpack what AI-enabled marketing actually looks like in practice. We get into how both of them found their way into crypto and marketing, why AI is no longer optional for modern marketers, and how tools like ChatGPT, Claude Code, n8n, OpenClaw, Higgsfield, and Suno are changing the way teams build, iterate, and ship. We also talk through the thinking behind the AI-Enabled Marketer Skoool community they recently launched, what they’re teaching inside it, and why the goal is not hype or course-bro fluff, but practical workflows that help marketers actually do better work. Along the way, we dig into AI literacy, automation, vibe coding, creative production, lead magnets, prompting, and the difference between just watching AI content versus actually building with it. If you’ve been feeling excited, overwhelmed, or slightly behind on AI, this one is for you. Timestamps 00:00 Intro and why AI-enabled marketing matters now 04:24 Jay’s background, how crypto clicked, and why marketing was the natural lane 06:27 Shane’s path from journalism and humanitarian work into Web3 08:41 What “AI-enabled marketing” actually means 12:15 Their current AI stack: ChatGPT, Claude, Claude Code, OpenClaw, Higgsfield, Suno, n8n, and more 15:40 Why the AI-Enabled Marketer community exists and who it’s built for 32:32 Live demo: AI literacy quiz, lead magnets, and practical marketing builds 40:50 How they’re teaching image and video generation for marketers 52:13 Rapid fire: underrated tactics, overrated tactics, and biggest lessons from the past year Show Notes Learn more: https://myosin.xyz/ai-enabled-marketer Skool: https://www.skool.com/the-ai-enabled-marketer/about

  4. Mar 3

    Why Robots Want Robot Money and What That Means for All of Us

    In Episode 51 of *Chain Reactions*, we sit down with Lex Sokolin, co-founder of [Generative Ventures](https://www.genventures.xyz/) and one of the sharpest voices at the intersection of fintech, crypto, and AI. With 15 years at the frontier of financial services, from Wall Street to early robo-advisors to co-leading DeFi strategy at ConsenSys, Lex brings a rare combination of depth and directness to the conversation.We dig into his core thesis: that AI agents are becoming economic peers, and those peers need financial infrastructure built for them. Lex breaks down how blockchain has collapsed five massive verticals of financial services into a single rail, why that's both unbelievably destructive and productive, and where the real commercial opportunities sit across payments, capital markets, and asset management.The conversation gets candid fast. Lex doesn't hold back on the crypto industry's tendency to dress up vaporware in legitimate opportunity, the evolution from Olas to Virtuals to OpenClaw as each wave of agentic AI gets slightly more real, and why the race to market to agents may ultimately benefit the fewest actual humans. We also get into the Visa and MasterCard question, whether Web3 is finance's Amazon-vs-Kmart moment, and why Tether's business model might be more interesting than Stripe's.We close with Lex's personal philosophy on turning the page, borrowed from a background in visual arts, and why building beats worrying in an era of exponential change.---**Timestamps**00:00 – Welcome and intro to Lex Sokolin of Generative Ventures02:36 – From Wall Street to robo-advisors to ConsenSys and beyond05:50 – The machine economy thesis and where the real opportunities sit08:29 – How blockchain collapsed five financial verticals into one rail10:56 – AI-first companies vs crypto-native firms and where they overlap13:42 – Latest developments and the pace of change in agentic AI14:24 – S-curves vs exponentials and why it matters for AI capabilities16:45 – The evolution from Olas to Virtuals to Lobsters20:41 – Will Visa and MasterCard be disintermediated by agents?27:39 – Amazon vs Kmart: is Web3 finance's greenfield moment?31:40 – How do you market to agents? The dystopian and practical answer36:54 – Spotting AI content in the wild and the normie gap38:32 – What Lex has changed his mind on about decentralization43:25 – What gets Lex most excited and most concerned heading into 202647:48 – The trap of AI consumption vs production49:27 – Biggest professional learning: being unafraid to turn the page---**Show Notes & Mentions**- 🧠 [Generative Ventures](https://www.genventures.xyz/) – Early-stage fund focused on the machine economy and robot money- 🧵 [Lex Sokolin on X](https://x.com/LexSokolin)- 📰 [Fintech Blueprint](https://www.fintechblueprint.com/) – Lex's newsletter reaching 110,000+ readers

  5. Feb 17

    Building State Street for Digital Assets: How Lagoon Is Powering the On-Chain Vault Economy

    In Episode 50 of Chain Reactions, Blake sits down with Nadia Sergujuk, Co-Founder of Lagoon, the permissionless vault management infrastructure that wants to become the State Street of digital assets. With a background spanning Danish law schools, PWC Legal in London, hedge funds managing $10B+ in AUM, and VC investing in deep tech, Nadia brings a rare cross-disciplinary lens to one of the fastest-growing categories in DeFi. We cover:– How Nadia went from law school in Copenhagen to hedge funds in London to co-founding an on-chain vault protocol– What vault management infrastructure actually is and why every stablecoin dollar eventually needs one– Why Lagoon's team put their own capital in first and how word of mouth drove early traction– The stablecoin explosion, neo banks in emerging markets, and why the digital dollar is eating the world– Privacy on-chain, the rise of institutional chains, and what keeps Nadia up at night (hint: quantum computing and the triple bubble) We also get into regulation as a tailwind, why Japan is the most slept-on institutional market in crypto, the innovator's dilemma facing Western Union and Visa, and why founder-led marketing beats KOLs every time. Timestamps 00:00 – Going live and Nadia joins from the Swiss Alps04:00 – From law school in Denmark to hedge funds in London06:30 – First exposure to Bitcoin in 2016 (and not buying it)08:20 – COVID, DeFi summer, and going all in on crypto09:30 – Meeting co-founder Remy at a conference in Bogota11:27 – What is Lagoon? Vault management infrastructure explained13:30 – Why permissionless and open source matters for trust16:26 – Business model: 10% of vault fees plus SaaS services18:00 – Go-to-market: putting your own money in the vaults first20:45 – BlackRock, Fidelity, and the TradFi wave coming on-chain faster than expected22:23 – Why regulation is actually a tailwind for Lagoon25:36 – Japan as the most slept-on institutional crypto market28:00 – Neo banks, stablecoin yield, and serving emerging markets30:30 – Why the digital dollar is irresistible in LatAm, Africa, and Southeast Asia37:00 – Conference circuit: DAF London, DAS New York, and founder-led presence40:06 – What keeps Nadia up at night: quantum compute and the triple bubble45:23 – Chain landscape: Solana's DeFi renaissance and BTCFi's comeback48:04 – Privacy on-chain: why institutions need it and how Lagoon will enable it51:35 – Rapid fire: founder-led marketing, KOLs, Merkl, and the power of peopleShow Notes & Mentions 🔗 Lagoon – Permissionless vault management infrastructure for digital assets🧵 Nadia on X🧵 Lagoon on X🏔️ DAS (Digital Asset Summit) – Upcoming in March in New York

  6. Feb 10

    Octant & Giveth Are Proving Blockchain is Doing Real Good

    In Episode 49 of Chain Reactions, we sit down with Mashal Waqar, Head of Marketing at Octant, and get a surprise drop-in from Griff Green, Founder of Giveth, to dig into how public goods funding actually works on Ethereum and why it matters more now than ever. We cover:– How Octant's model works: lock GLM, earn ETH, and choose to fund public goods or keep the yield– The surprisingly heated debate over what counts as a "public good" (yes, Pizza DAO came up)– Why blockchain unlocks speed, transparency, and community-driven capital allocation that traditional grants can't match– Griff's wild story of The DAO hack, how edge case funds turned into $200M+, and the launch of the new DAO Security Fund– The case for an Ethereum security coalition and why L2s need to fund shared infrastructure Mashal shares her journey from running a media company with tens of millions of readers to burning out, discovering crypto through NFTs and Gitcoin, and co-authoring the first State of Web3 Grants report. We also get into real-world impact stories, from funding water filters in Gaza to helping doctors in Syria get paid through crypto, and why sustainable funding through DeFi yield beats depleting treasuries. Plus, a great riff on AI in public goods, the Zakat use case for crypto, and why execution beats everything. Timestamps 00:00 – Intro and what's on everyone's timeline right now02:08 – Welcome to Chain Reactions and introducing Mashal from Octant03:54 – Mashal's journey from media founder to crypto marketer06:28 – How NFTs and Crypto Covens pulled her back into Web308:53 – Co-authoring the first State of Web3 Grants report and discovering Octant10:25 – What Octant is and how the GLM staking model works13:15 – What actually counts as a public good (and the Pizza DAO debate)16:49 – The $1M Ethereum creator round and lessons from vetting 1,000+ applications18:30 – DeFi vaults, sustainable funding, and the new StreamVote experiment23:30 – Why blockchain unlocks faster, more transparent funding than traditional grants26:34 – Remittances, financial access, and the personal case for crypto in emerging markets33:24 – Griff joins: founding Giveth, The DAO hack, and rescuing $200M+ in edge case funds39:21 – The multiplier effect and why matching makes it hard not to donate44:18 – Launching the DAO Security Fund inspired by Octant's model48:45 – AI experiments at Octant, building with AI, and the case for AI in public goods56:29 – Vitalik's L2 tax tweet, Ethereum sustainability, and the need for a security coalition1:00:00 – Rapid fire: execution beats everything and don't count your chickens Show Notes & Mentions 🧠 Octant – Public goods funding platform on Ethereum🎁 Giveth – Donation platform and public goods movement since 2016🧵 Mashal on X🧵 Griff on X🧵 Octant on X🧵 Giveth on X🏗️ DAO Security Fund – Griff's new project to secure DAO funds and fund Ethereum security🪙 Golem / GLM – Token powering Octant's staking and funding model🌱 Gitcoin – Grants platform for open source and public goods🍕 Pizza DAO – Community funding pizza parties worldwide (public good or not?)🤖 Virtuals / 60days.ai – AI agent launchpad mentioned by Griff⭐ Stellar – Referenced for crypto-powered aid to doctors in Syria📊 [Blockchain for Good Report](https://docsend.com/v/9dm2p/myosin-blockchainsforgood](https://docsend.com/v/9dm2p/myosin-blockchainsforgood)) – Myosin's collaborative research report on blockchain impact

Ratings & Reviews

5
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About

Myosin.xyz is the ultimate decentralized marketing network, accelerating the onchain revolution to create a more equitable internet. Subscribe to listen to our shows Chain Reactions & Netcetera. Chain Reactions is a weekly livestream where we talk about the latest in blockchain, break down interesting marketing campaigns, and have fun w/ourselves, members, and friends of Myosin. Netcetera is a series where we talk to leaders at the forefront of innovation, whether at traditional brands, web3 or AI companies, to demystify the innovations sharing the new internet.