The NatureCity Podcast

Nature City
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The Nature City Podcast dives into the world of supplements and nutrition to help you make the best decision for your health and lifestyle needs. Hosted by CEO and Founder Carl Pradelli, The Nature City Podcast is your go-to podcast for all things supplements, nutrition, and much more. To learn more about Nature City and our work, visit https://www.naturecity.com/ You can also follow us on Youtube to watch the latest episodes, of the Nature City Podcast

  1. JAN 29

    Omega-3s, Brain Health, and Why Blood Levels Matter

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published study that takes a deeper — and more impactful — look at omega-3s and brain health. Rather than relying on food questionnaires or supplement surveys, this new research measured omega-3 blood levels, offering a clearer picture of how EPA and DHA status relates to the earliest biological stages of age-related cognitive decline. The findings reinforce an idea Carl has emphasized before: when it comes to omega-3s, long-term blood levels matter far more than short-term intake. Carl revisits key insights from Episode 115 on omega-3s and brain health, then explains what makes this study different — including its focus on the Omega-3 Index as a predictor of cognitive aging risk. The research showed that individuals with an Omega-3 Index above 8% had significantly better brain aging outcomes, while most people in Western populations fall far below that range. The episode also explores why simply “taking fish oil” doesn’t guarantee results. Carl explains the importance of consistent intake, proper dosing, balanced EPA and DHA ratios, and — critically — absorption and bioavailability. He breaks down why some people see meaningful benefits from omega-3s while others don’t, and how advanced delivery systems can dramatically impact results. If you’re interested in protecting brain health decades before symptoms appear — and want practical, measurable strategies instead of guesswork — this episode offers clear guidance grounded in human research. WHAT YOU’LL LEARN Why this new omega-3 study focused on blood levels, not dietary intakeHow omega-3 status relates to early biological stages of cognitive declineWhat “early onset” cognitive changes mattersWhy the Omega-3 Index is the most reliable marker of omega-3 adequacyWhat an Omega-3 Index above 8% means for long-term brain healthWhy most people never reach protective omega-3 blood levelsThe distinct roles of DHA (structure) and EPA (healthy inflammation response & blood flow) in the brainGenetics don’t determine destiny – lifestyle and nutrition matter alsoHow absorption and delivery systems impact omega-3 effectivenessHow omega-3 testing turns supplementation into a measurable strategy SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical healthy aging insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Omega3 #BrainHealth #CognitiveAging #HealthyAging #Omega3Index #EPA #DHA #LongevityScience #SupplementScience #HealthSpan

    9 min

  2. JAN 22

    New Science: Resveratrol Can Help Skin Appearance

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli breaks down a newly published human study on resveratrol — and why its findings go beyond skin-deep benefits. Resveratrol has long been discussed for its role in healthy aging, heart health, and longevity. But this new research shifts the spotlight to something many people notice first as they age: visible changes in skin firmness, elasticity, and wrinkles. What makes this study especially noteworthy is that it didn’t use just any resveratrol — it used Veri-te® resveratrol, the fermented form found in NatureCity’s TrueResveratrol. Carl walks through exactly what the study showed, who participated, the surprisingly low dose that was used, and why this specific form of resveratrol appears to work differently than many high-dose products on the market. He also explains why improvements in skin health often reflect broader biological support — including antioxidant protection, a healthy inflammation response, mitochondrial function, and cellular repair. Beyond skin aging, the episode explores how resveratrol — particularly the low dose Veri-te® — has also been studied for bone health, cardiovascular support, metabolic function, and brain health, reinforcing its role as a foundational, multi-system aging nutrient rather than a cosmetic-only supplement. If you’re curious about resveratrol but want evidence-based guidance — not hype or mega-dose guesswork — this episode offers clarity, context, and practical takeaways grounded in human research. WHAT YOU’LL LEARN Why this new resveratrol study focused on visible skin agingWho was studied and why the results are especially relevant for adults over 40The specific skin aging markers that improved in the studyWhy the study used just 150 mg per day — and why that mattersHow skin health reflects deeper cellular aging processesWhy not all resveratrol supplements are created equalHow fermented resveratrol differs from conventional sourcesThe connection between resveratrol, bone health, and agingHow resveratrol supports cardiovascular, metabolic, and brain healthWhy ingredient form and purity matter more as we age SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical healthy aging insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Resveratrol #HealthyAging #SkinHealth #BoneHealth #LongevityScience #AntiAgingResearch #SupplementScience #HealthSpan #VeriteResveratrol

    9 min

  3. JAN 16

    Do You Really Need Expensive Longevity Supplements?

    In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a step back from the hype surrounding cutting-edge longevity supplements to ask a more practical — and important — question: Do you really need expensive, trendy longevity products to support healthy aging? With longevity now dominating wellness headlines, many supplements promise to slow aging, lengthen telomeres, boost NAD+, or activate autophagy — often at a steep monthly cost and with limited long-term human research. Carl explains why longevity isn’t driven by a single “magic molecule,” but by a network of systems including a healthy inflammation response, oxidative stress protection, cardiovascular health, immune system regulation, brain function, and cellular integrity. In this episode, Carl breaks down how well-established nutrients — backed by decades of human research — already support many of the same biological pathways targeted by newer longevity compounds. He highlights three foundational supplements that almost everyone should prioritize first for both health span and longevity: Vitamin D (especially when paired with Vitamin K2)Omega-3 fatty acids from high-quality fish oilVitamin E tocotrienols Carl explains how these nutrients support the same health systems targeted by newer longevity compounds, and even mitochondrial function and  telomere integrity too — all without the uncertainty and cost of newer longevity “stacks.” You’ll also learn why optimizing the fundamentals can deliver powerful aging benefits today, not just theoretical lifespan gains decades from now. If you’re curious about longevity but want science-backed, realistic guidance before spending hundreds of dollars a month on supplements, this episode is for you. WHAT YOU’LL LEARN Why longevity isn’t controlled by one single nutrient or pathwayThe hidden downside of expensive, cutting-edge longevity supplementsNetwork of systems that influence agingWhy Vitamin D is one of the most underestimated longevity nutrientsThe role Vitamin K2 plays alongside Vitamin DWhy omega-3s are often called the “original longevity supplement”How omega-3s support heart health, brain health, and telomeresWhat tocotrienols are — and why most vitamin E supplements miss themHow tocotrienols support cellular, mitochondrial, and brain healthWhat telomeres really are and how you can protect themWhy consistency beats novelty when it comes to healthy aging SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical longevity insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore NatureCity supplements at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #Longevity #HealthyAging #VitaminD #Omega3 #Tocotrienols #Telomeres #AntiAgingScience #HealthSpan #SupplementScience

    11 min

  4. JAN 9

    Do Coffee & Tea Affect Bone Health?

    Is your daily coffee helping you… or quietly harming your bones? And could tea actually strengthen them? In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli revisits a popular question from a past episode: Is caffeine bad for bone health? This time, he breaks down new research published in late 2025 that followed nearly 10,000 women over age 65 for a decade — revealing some surprising differences between coffee and tea when it comes to bone mineral density. Carl explains why moderate coffee intake is usually safe, when it can become a concern (especially for postmenopausal women), and why tea — particularly green and white tea — may actually support stronger bones thanks to powerful polyphenols. He also shares practical, realistic strategies for protecting bone health without giving up your morning cup of coffee. Finally, Carl explains why bone health requires far more than calcium alone, and how NatureCity’s Tru Osteo® and Tru Osteo Plus® formulas are designed to support not just slowing bone loss — but potentially improving bone density over time. If you care about aging well, staying active, and keeping your bones strong for the long haul, this episode is a must-listen. WHAT YOU’LL LEARN What the newest long-term study reveals about coffee, tea, and bone densityWhy tea drinkers showed higher bone mineral density over 10 yearsWhen coffee consumption may negatively affect bone healthHow caffeine impacts calcium absorption (and why the effect is smaller than you think)Why postmenopausal women and low-calcium diets need extra cautionThe surprising role alcohol plays in worsening coffee’s bone effectsHow tea polyphenols and catechins support bone-building activitySmart ways to enjoy coffee while protecting your bonesWhy calcium alone isn’t enough for strong, healthy bonesHow Tru Osteo® and Tru Osteo Plus® support comprehensive bone health SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical wellness insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and your favorite streaming platform 💬 Comment below with your biggest takeaway from this episode Explore Tru Osteo® and Tru Osteo Plus® at 👉 https://www.naturecity.com FOLLOW US Instagram: @NatureCitySupplements Facebook: NatureCity Supplements #NatureCityPodcast #BoneHealth #CoffeeAndBones #TeaBenefits #HealthyAging #Calcium #VitaminD #VitaminK2 #OsteoporosisPrevention

    8 min

  5. 12/19/2025

    The PEA Advantage: Joint Comfort, Faster Recovery, Sleep & Stress Support

    Joint discomfort, sore muscles, restless nights, and being overwhelmed by daily stress seem like separate challenges — but did you know your body naturally makes a nutrient that offers support for all of them? In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli takes a deep dive into PEA (palmitoylethanolamide)—a naturally occurring fatty compound your body uses to manage discomfort, stress, and support a healthy inflammation response. Carl explains how PEA levels tend to decline with age (when we need PEA most), why most PEA supplements fall short, and how the best studied form of PEA, called Levagen+, overcomes absorption challenges and delivers results using the novel LipiSperse delivery technology. With over 14 published human studies, Levagen+ has been shown to support joint comfort, flexibility, muscle recovery, sleep quality, cognitive performance, immune health, and more. This is why we made Levagen+ a cornerstone ingredient in TrueJoint FLX, NatureCity’s premium joint formula, which was designed to help you start feeling better within days — and help keep you mobile and active with better joint function over time. If you want to support joint health, recover faster, sleep better, and support long-term resilience as you age, this episode is a must-listen. WHAT YOU’LL LEARN What PEA is and how your body naturally uses it PEA production declines with age — so supplementation makes sense Why Levagen®+ is the best PEA for supplements Research-backed benefits for joint comfort and flexibilityHow Levagen+ supports faster muscle recovery and performanceThe role PEA plays in sleep quality, stress support, and cognitionEmerging research on immune, gut, metabolic, and menstrual supportWhy NatureCity includes Levagen+ in its TrueJoint FLX formula TIMESTAMPS 0:00 – Welcome & why PEA deserves attention 1:04 – What PEA is and where it comes from 1:51 – PEA levels decline with age 2:15 – The absorption problem with standard PEA supplements 2:38 – Why Levagen®+ is different 3:02 – LipiSperse® technology & absorption benefits 3:30 – Joint comfort, stiffness, and flexibility research 4:40 – Muscle recovery, soreness, and performance support 5:42 – Sleep quality, stress balance, and nervous system support 6:15 – Cognition, BDNF, and mental alertness findings 6:58 – Heart rate variability support & stress resilience 7:21 – Emerging research: menstrual comfort, gut & metabolic health 8:04 – Final thoughts & where to learn more SUBSCRIBE & CONNECT Don’t miss future episodes packed with supplement science and practical wellness insights. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and more 💬 Comment below with your biggest takeaway from this episode Explore the full TrueJoint FLX formula at a href="https://www.naturecity.com" rel="noopener...

    8 min

  6. 12/11/2025

    Keeps Your Skin Hydrated – With Less Hair Loss Too

    Skin creams and serums can only do so much to keep your skin and hair looking their best. Support starts from within your body. This is especially true when it comes to reinforcing your skin’s moisture barrier and protecting hair cuticles with ceramides. In this episode of the NatureCity Podcast, host and supplement expert Carl Pradelli introduces Ceramosides®—a plant-based, gluten-free ceramide supplement that’s changing the way we support skin and hair health. Carl explains how Ceramosides® works from within to help increase skin hydration and elasticity, while reducing the appearance of fine lines and wrinkles. More recently, Ceramosides®  has also been shown it can help create a healthier scalp environment that supports stronger, fuller-looking hair, and reduces normal hair loss. Backed by five published scientific studies and a new consumer trial with 95 men, this episode is a must-listen if you’re interested in aging more gracefully, reducing hair shedding, or optimizing your skincare routine. You'll also find out why Ceramosides® is uniquely effective compared to other ceramide ingredients - and how it perfectly complements other researched ingredients like keratin and collagen in NatureCity’s new TrueNuGrow+ Hair & Skin Formula. If you want to keep your skin and hair looking its best, or you’re just curious about how science-backed supplement ingredients can boost your natural glow—this episode is for you. WHAT YOU’LL LEARN What ceramides are and how they help protect your skin and scalpHow Ceramosides® complements collagen, keratin, and topical creamsWhy this ingredient can be a game-changer for both men and womenWhat the recent studies reveal about skin hydration and appearance, hair loss and hair growthWhy NatureCity uses this patented ingredient in its TrueNuGrow+ formula SUBSCRIBE & CONNECT Don't miss future episodes packed with supplement science and real wellness solutions. ✅ Subscribe to the NatureCity YouTube channel 🎧 Listen on Spotify, Apple Podcasts, and more 💬 Let us know your favorite part of this episode in the comments! Explore the full True NewGrow Plus formula at https://www.naturecity.com WELCOME TO THE NATURECITY YOUTUBE CHANNEL Here you'll find expert-led insights into natural supplements and holistic health. Hosted by Carl Pradelli, NatureCity’s co-founder, our videos blend trusted science with practical advice to help you make informed wellness decisions. Each episode dives deep into key ingredients, emerging research, and proven supplement stacks designed to support energy, beauty, digestion, and longevity. FOLLOW US Instagram: @NatureCitySupplementsFacebook: NatureCity Supplements #NatureCityPodcast #Ceramides #HairSupplements #SkinHealth #Ceramosides

    8 min

  7. 11/21/2025

    Over 50% Of Berberine Supplements Tested Failed

    Fraudulent products are a real concern for supplement buyers.  The latest example of this was revealed in lab testing of top selling berberine supplements purchased on Amazon.  The results were pretty shocking with the majority of supplements seemingly containing less than 10% of the berberine claimed on the product label – with a couple containing none at all. In this eye-opening episode of the NatureCity Podcast, host and supplement industry veteran Carl Pradelli breaks down the findings and why if a supplement price seems too good to be true, it probably is.  You’ll also find out why solely relying on Amazon star ratings and badges may not protect you from purchasing a fraudulent supplement. Carl also dives into why berberine has become a target for fraudulent supplement makers: it's growing in popularity for supporting blood sugar, metabolic health, and weight management, but a high dose is required for results (which make it more costly to produce). This has opened the door for bad actors to cut corners. Carl also outlines the biological role of berberine, including how it supports AMPK enzyme activity, blood sugar metabolism, and insulin function. He also discusses GlucoVantage, a newer form of berberine (dihydroberberine) that offers superior absorption and far fewer stomach and gastrointestinal issues—making it a game-changer for anyone interested in the benefits of berberine. This episode doesn’t just warn you—it equips you. Learn how to spot quality supplements, why price matters, and how combining berberine with strength training can improve body composition and reduce fat storage. If you’re looking to optimize your supplement stack or protect your health investment, this episode is a must-listen.  Don’t risk your health or waste your money. Subscribe for honest supplement insights and insider tips that protect your wellness journey. WHAT YOU’LL LEARN How top selling berberine supplements failed a basic quality test.Why low prices often mean low quality. What makes berberine effective—and how to get the most from it.How new ingredient technology like GlucoVantage solves major challenges with berberine.Why combining berberine with exercise can help your body composition. Subscribe for weekly supplement science breakdowns and wellness tips. What’s your biggest takeaway from this episode? Let us know in the comments. Shop NatureCity’s TrueBerberine at https://www.naturecity.com WELCOME TO THE NATURECITY YOUTUBE CHANNEL On the NatureCity YouTube Channel, you’ll find expert-led insights into natural supplements and digestive health. With over 20 years of experience, Carl creates videos packed with practical, science-backed information to help you make informed health choices. Our channel provides in-depth overviews of our top supplements, like the TrueDYB formula. We break down how each ingredient supports digestive health, immunity, and overall wellness, so you can see exactly how our products are designed to maximize benefits. If you’re curious about what makes these supplements effective, we’ll guide you through the science and thought behind each one. Our videos cover essential digestive health topics, such as managing leaky gut and boosting nutrient absorption. You’ll find straightforward tips to support your gut health and better understand the role of supplements in your daily wellness. Each video simplifies complex nutritional concepts, explaining how popular ingredients interact to support your body’s natural functions. Subscribers also gain access to honest Q&A sessions and product reviews. If you have questions about a specific supplement or a health concern, we provide...

    9 min

  8. 11/14/2025

    New Melatonin Study Raises Red Flags: What Does It Mean?

    A new study sponsored by the American Heart Association links long-term melatonin use to increased risk of heart failure and early death—but is the data trustworthy?  What does this mean for supplement users? In this episode, Carl Pradelli breaks down the controversial melatonin study making headlines and the potential issues with how the study was conducted.   Carl also shares his concerns with taking melatonin regularly or taking excessive amounts. He also reveals the spice that can be a better option as a supplement because it supports your body’s natural melatonin production process and has been shown to help increase sleep quality and mood upon awakening. Subscribe to stay ahead of the health curve. What You’ll Learn: The limitations of the “preliminary” results linking long term melatonin use to risk of heart failureThe significant flaws in the study structureOthe concerns with regular melatonin use A natural way to support your body’s own melatonin productionSupporting healthy melatonin levels without disrupting the sleep/wake cycle Subscribe for weekly natural health insights and supplement strategies. What do you think about melatonin—have you had a positive or negative experience? Drop your thoughts in the comments 👇 Explore TrueZs and support natural melatonin production: https://www.naturecity.com #NatureCityPodcast #MelatoninRisks #SleepSupplements

    11 min
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About

The Nature City Podcast dives into the world of supplements and nutrition to help you make the best decision for your health and lifestyle needs. Hosted by CEO and Founder Carl Pradelli, The Nature City Podcast is your go-to podcast for all things supplements, nutrition, and much more. To learn more about Nature City and our work, visit https://www.naturecity.com/ You can also follow us on Youtube to watch the latest episodes, of the Nature City Podcast

Information

  • Creator
    Nature City
  • Years Active
    2023 - 2026
  • Episodes
    126
  • Rating
    Clean
  • Copyright
    © Copyright 2026 Nature City
  • Show Website
    The NatureCity Podcast

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