Neurology: Disease Deep Dive

Practical Neurology
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  • LIFE SCIENCES
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The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.

Episodes

  1. 12/15/2025

    Detecting Multiple Sclerosis Earlier: PRLs and the Evolving McDonald Diagnostic Criteria

    This episode explores new evidence showing that paramagnetic rim lesions (PRLs) are highly prevalent early in multiple sclerosis (MS) and can differentiate MS from mimics with striking accuracy. Dr. Daniel Ontaneda, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, and Dr. Pascal Sati, Cedars-Sinai Medical Center,  Los Angeles, CA, discuss how PRLs, paired with optimized susceptibility-based MRI, are reshaping diagnostic confidence and informing the latest revisions to the McDonald criteria.

    30 min

  2. 12/03/2025

    Modern Glioma Management: Integrating Molecular Markers and New Targeted Therapies

    Patrick Y. Wen, MD, Dana-Farber Cancer Institute, Boston, MA, discusses current standards of care for low- and high-grade gliomas, including the importance of comprehensive molecular testing, the World Health Organization classification of tumors of the central nervous system, and newly available therapies.

    14 min

  3. 12/02/2025

    Maturing with Migraine: Practical Guidelines for Transitioning Adolescent Migraine and Headache Patients into Adult Practice

    Hope O’Brien, MD, MBA, FAHS, FAAN, Founder and CEO of the Headache Center of Hope, Cincinnati, OH, discusses challenges and considerations for adult headache neurologists who are onboarding adolescent patients as they transition from pediatric practice. Dr. O’Brien highlights a framework with strategies for a seamless transition, while noting best practices for promoting patient autonomy and mental wellbeing.

    24 min

  4. 10/27/2025

    Advances in ALS: New Targets, Trials, and Care Strategies

    Merit Cudkowicz, MD, Julieanne Professor of Neurology, Harvard Medical School, Boston, MA, discusses the evolving landscape of treatment for ALS, including FDA-approved disease-modifying therapies, the importance of genetic testing, the emergence of gene therapies, and the promising clinical trial pipeline targeting genetic and sporadic forms of ALS.

    15 min

  5. 10/22/2025

    Cerebrovascular Inflammatory Conditions: Diagnostic Challenges and Treatment Considerations

    Abbas Kharal, MD, MPH, Neurologist at Cleveland Clinic Neurological Institute, Cleveland, OH, provides a review of cerebrovascular inflammatory conditions, with an emphasis on diagnostic challenges, the evolving treatment landscape, and the use of imaging and clinical responses to assist clinicians with early detection and differentiation of these conditions.

    19 min

  6. 06/06/2025

    The Evolving Therapeutic Landscape for Parkinson Disease

    Mark Stacy, MD, William E. Murray Professor of Neurology, Medical University of South Carolina, Charleston, SC, discusses the evolving therapeutic landscape for Parkinson disease, highlighting promising advances in neuroprotective therapies, biomarkers, personalized medicine, and innovative clinical trial designs that aim to improve both treatment outcomes and accessibility.

    21 min

  7. 06/04/2024

    Advances in the Evaluation of TBI

    Welcome to Neurology: Disease Deep Dive. In this episode, Dr. Beth McQuiston, MD, RD, Medical Director at Abbott Laboratories, and Dr. David Okonkwo, MD, PhD, Professor of Neurological Surgery, Clinical Director of the Brain Trauma Research Center, and Director of the Neurotrauma Program at University of Pittsburgh Medical Center discuss evaluation and advances in evaluation of traumatic brain injury. Dr. McQuiston is talking with us today on behalf of Abbott, which is sponsoring this podcast. Dr. Okonkwo is a physician scientist whose research on blood biomarkers was instrumental for advancing traumatic brain injury biomarker diagnostics. Resources from this episode: More information on concussions Information on i-STAT TBI test cartridge with the i-STAT Alinity instrument Information on Alinity i TBI test

    21 min

  8. 02/29/2024

    NMOSD Part 3 - Overview of treatment, including goals, triggers, and considerations for switching therapies

    In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents an overview of NMOSD treatment, including goals, triggers, and considerations for switching therapies. DA-UNBR-US-02296-2 05/2024 Sponsored by Horizon Therapeutics

    20 min

  9. 02/15/2024

    NMOSD Part 2 - The importance and tools for monitoring NMOSD, and signs, symptoms and evaluation of disease activity

    In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents the importance and tools for monitoring NMOSD, and signs, symptoms and evaluation of disease activity. DA-UNBR-US-02295-2 05/2024 Sponsored by Horizon Therapeutics

    23 min

  10. 02/01/2024

    NMOSD Part 1 - Overview and important considerations for diagnosis

    In this series, Derrick Robertson, MD, Director of the Multiple Sclerosis Division at the University of Southern Florida discusses multiple aspects of NMOSD. Dr. Robertson is talking with us today on behalf of Horizon Therapeutics which is compensating him for his services and is sponsoring this podcast. In this episode, Dr. Robertson presents an overview of NMOSD, and important considerations for diagnosis. DA-UNBR-US-02294-2 05/2024 Sponsored by Horizon Therapeutics

    32 min

  11. 12/05/2023

    Narcolepsy, Idiopathic Hypersomnia, and General Sleep Disorders

    In this episode, Rajkumar Dasgupta, MD, Clinical Associate Professor at Keck School of Medicine of USC and sleep specialist, provides an in-depth review of what's new in sleep disorders, with a special focus on updates in narcolepsy and idiopathic hypersomnia.

    28 min
  • 11 Episodes

Ratings & Reviews

5
out of 5
5 Ratings

About

The field of neurology is vast and complex. This series provides thorough conversations with key expert physicians on neurologic conditions including the evolution of our understanding and treatment of these conditions.

Information

  • Creator
    Practical Neurology
  • Years Active
    2023 - 2025
  • Episodes
    11
  • Rating
    Clean
  • Copyright
    © 2024 Practical Neurology

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