What can a 225,000-person study reveal about the environmental, lifestyle, and biological factors that shape health and disease over time? In this episode, Vicki Kirsh and Sandford Borins discuss how long-term health data, biological samples, and administrative health records are being used to advance discoveries in chronic disease, cancer, and health-system equity. The Ontario Health Study is housed at and funded by the Ontario Institute for Cancer Research (OICR). Dr. Victoria (Vicki) Kirsh is Interim Director of the Ontario Health Study (OHS). She was appointed to this role in 2025 after serving as the study’s Scientific Associate. Since 2023, she has also been National Scientific Coordinator for the Canadian Partnership for Tomorrow’s Health (CanPath), a national network of regional cohorts that includes OHS. Her research focuses on the causes and early detection of cancer. Vicki holds a Ph.D. in Epidemiology from Yale University and completed a fellowship at the U.S. National Cancer Institute. She is an Assistant Professor at the Dalla Lana School of Public Health, University of Toronto. Sandford Borins is Professor Emeritus of Public Management at the University of Toronto, retiring in 2020 while remaining highly active in teaching, research, governance, and public engagement. In 2026, he and co-author Beth Herst published Public Representations: Screen Stories, Narrative, and the Public Sphere. He continues to teach narrative and management, write a weekly blog, and chair the independent review committee for a mutual fund company. His distinguished career includes twelve books, eighty scholarly publications, nearly 7,000 Google Scholar citations, strong teaching accomplishments, and leadership as founding chair of the University of Toronto Scarborough’s Department of Management. Awarded the King Charles III Coronation Medal, his research focuses on narrative and public sector innovation. He holds undergraduate, master’s, and doctoral degrees from Harvard University. Resources Ontario Health Study EPISODE CREDITS: Produced, edited and mixed by Will Mcintyre, Richard Villeneuve and Pop Up Podcasting Artwork designed by Stella-Luna Ha Music licensed through Melodie Music LINKS: Be sure to follow and tag ICES on Facebook, Instagram and LinkedIn. To find out more about our organization, visit us at ices.on.ca