Go Un-Pro

Brent W. Laartz

Go Un-Pro with Dr. Brent W. Laartz, MD FIDSA: Living an Unprocessed Life for Longevity and Healthspan Have you ever known that something is SO good for you that you just can't wait, but life gets in front of you and prevents you from doing it? The inaction and procrastination could occur for a variety of reasons, and we will delve into my motivations and affirmations of a healthy life from this day forward. I am starting this series of videos and articles so that I can be accountable to myself regarding the changes in my diet that I REALLY NEED to survive into my 90s without heart disease, dementia, and arthritis. And hopefully, as you follow along, you can make your own improvements that will extend your life and prevent the horrible illnesses that are heart disease, dementia, and arthritis. Can I introduce myself? I'm Dr Brent W. Laartz, and I am an Infectious Diseases physician with a Master's in Neuroscience, author, creator, and entrepreneur. I've been involved with medical education for almost all my life and have been sharing my knowledge, teaching students, patients, and other doctors as faculty of a medical school, in hospitals, and clinics around the world. I'm ashamed to admit that I have lived a life of processed foods despite knowing the facts that are stacked against me if I continue living this way. My most recent research into longevity and its connection to our diet, exercise, sleep, and mental health, all with help from our microbiome, the bacteria living in our body, has me wanting to shout this information to the masses from the rooftops! This is so important that I am going to communicate what I have learned in every forum possible. Simply put, I am not going to do it anymore, and I am going to stay accountable to myself so that I follow through with it this time. Hence, the launch of this podcast, which I have been wanting to do for quite some time now. In addition, I am also launching publicly available Master courses that will delve incredibly deeply into the science behind diet and other interventions that will help me live well into my '90s and 100s, but not just live, but REALLY live! This is the concept of Healthspan. I know there are a lot of billionaires who are prominent in the media, trying to live forever, spending millions of dollars, but I am here to prove you can do it without spending a lot of money. The interventions I am doing will cost a little more money, but my budget is to only increase expenditures by a few $100 a month. The thing is, we are so accustomed to our artificial products that we deep down believe they are good for us. Don't accept this BS from your food, expect better. Most physicians I know are not living a healthy life, and until the past 6 months, that generalization included me. If you think otherwise, let me paint the picture of a typical doctor's lounge in the hospital or the home kitchen of your local physician. Hospital kitchens use the cheapest oils, fried foods, and beef, butters with mashed potatoes, pre-manufactured eggs, mass-produced bacon, candy, and ice cream sandwiches. This is what I was eating day in and day out, working 26 days per month. My cholesterol was skyrocketing, and my weight had peaked at 165 pounds on a 5-foot-7-inch frame. Then I took stock of my life. And it was just in time, too, for my kids were graduating from high school. At least I didn't have the excuse of cleaning my kids' plates anymore. I suspect that if you are listening to this podcast, reading this article, or taking this course, you are interested in living a more unprocessed life. If you are like me, you have reached a point in your life where you realize your health could be at a tipping point. I was lulled into thinking I was living a healthy life because I exercised and ate right some of the time. But that delusion could not have been further from the truth. I was drinking alcohol at least a few days per week, drank sodas at least a few days a wee

  1. 1d ago

    Week 12: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 12: A Doctor's 52 Week Journey to an Unprocessed Life  Spectacular Speaker-Focused Summary: Go Unpro Podcast Week 12 – Proof of Life, Microbiome Mastery & Unprocessed Progress **Dr. Brent Laartz**  A candid weekly update on personal setbacks (illness, house move) while celebrating small victories. He reinforced the centrality of microbiome health, outlined specific Week 12 targets across diet, movement, sleep, creativity, and plastics reduction, and reviewed cumulative progress from Weeks 1–12. The host emphasized accountability, whole-food preparation, and gradual lifestyle upgrades toward a 90–95% unprocessed life by Week 52. Key Points and Decisions **Microbiome focus**: Daily movement + increased fermented foods remain foundational; microbiome influences hormones, immunity, mood, and performance. **Diet upgrades**: Increase Sunday prep of dairy-free yogurts, beans, and vegetables; move from 2–3 to 3–4 vegan days/week; reduce alcohol to 8 drinks/month; favor low-sugar NA drinks for social settings. **Movement**: Target 7–8 combined cardio/resistance sessions weekly (including double-activity days); add one group class (Pilates/yoga); prioritize morning exercise when possible; schedule post-move tennis. **Sleep optimization**: Install automatic blackout curtains in new home; enforce no food after 8 p.m., no exercise/hot tub after 7 p.m.; maintain cool, dark bedroom. **Creativity & connection**: Begin weekly social painting/art sessions; continue journaling, affirmations, and reconnecting with friends/family. **Plastics reduction**: Replace parchment paper with vegetable-based Patapar paper; maintain ongoing elimination of plastic kitchenware and household products. **Cumulative habits retained**: 40+ whole foods weekly, daily greens/berries/fermented foods/fiber, time-restricted eating, meditation, gratitude, language learning, and community volunteering. Next Steps Implement increased food prep and vegan-day targets immediately. Test Patapar paper in cooking and report results. Install blackout curtains and automation in new residence post-move. Schedule recurring social painting session and one weekly vegan restaurant outing. Continue daily accountability tracking and morning sunlight exposure. Maintain all prior 12-week habits while layering on Week 12 enhancements toward the 52-week unprocessed goal.

    32 min
  2. Jun 9

    Sunday Science 2026 Episode 7 Microbiome Enhancing Endurance and Strength

    Spectacular Speaker-Centric Summary: Unlocking Microbiome Power for Endurance and Strength in Sunday Science Summary of Each Speaker **Dr. Brent Laartz**: Hosted the discussion on the bidirectional microbiome-exercise relationship, covering mechanisms like lactate clearance and short-chain fatty acid production, citing studies on Veillonella, Lactobacillus salivarius, and Lactobacillus plantarum, and outlining practical takeaways for enhancing performance. Key Points and Decisions Exercise improves microbiome diversity and gut health overall, though excessive intensity may temporarily increase permeability; elite athletes show enriched beneficial bacteria like Veillonella due to lactate-rich environments. Key bacteria (Veillonella, L. salivarius, L. plantarum) clear lactate, boost short-chain fatty acids (propionic, acetic, butyric acids) for muscle energy and glycogen sparing, and support intestinal barrier integrity via tight junctions. Mouse and human studies (e.g., Scheiman 2019 in Nature Medicine; Lee 2020 in Microorganisms; triathlete trial with L. plantarum PS128) demonstrated 2-3x increases in endurance and grip strength without altering VO2 max. Decision: Prioritize natural approaches like exercise and diet over unproven supplements; Veillonella products exist but require further evaluation. Next Steps Incorporate exercise to foster lactate-utilizing bacteria and consume prebiotic fibers (inulin, chicory root, garlic) to support their growth. Explore targeted Lactobacillus and Bifidobacterium strains via diet or supplements while ensuring adequate fiber for colonization; consider homemade yogurt with verified lactate-utilizing species. Follow Sunday Science episodes on social platforms, podcasts, YouTube, and GoOnPro.com for ongoing science-based wellness insights.

    24 min
  3. Jun 6

    Week 11: A Doctor's 52 Week Journey to an Unprocessed Life

    **Key Points and Decisions**  May successes included daily greens/berries, strong time-restricted feeding, good ethanol control, and realignment after setbacks; vegan days averaged 2–3 per week with some packaged-food lapses during on-call weeks.  Biological age tested 14 years younger and cardiovascular age 5 years younger despite minor blood-work artifacts from fasting and allergies.  Core stack limited to calcium, vitamin D, B12, omega-3, acarbose, and the five pillars (diet, movement, sleep, connection, plastics); rejected aesthetic interventions such as Botox or mTOR-inhibiting creams. Decision to avoid "grifting," product sales, or extreme longevity-expert trends; focus remains on education and personal documentation.  Acknowledged challenges from girlfriend's baking and family sugar exposure while committing to natural mTOR inhibition via calorie restriction, fiber, and exercise. **Next Steps**  Increase vegan days to 3–5 per week with daily greens, berries, beans, and fermented foods (including new turmeric-ginger-onion-cabbage ferments).  Add a fourth training day (two-a-day format) targeting 3 cardio + 3 resistance sessions plus tennis for balance and bone health.  Install blackout drapes and maintain 66°F room; enforce 8 p.m. snack cutoff for improved sleep.  Set up home gym, music corner (guitars, harmonica, saxophone), and pursue classes/clubs for social connection and creativity.  Eliminate remaining plastics (bottles, pens, kitchen storage) by switching to glass, steel, and natural fabrics. Continue weekly resident teaching on microbiome and functional health; prepare for June 18 house closing while maintaining podcast consistency.

    1h 6m
  4. May 6

    Week 10: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 10: A Doctor's 52 Week Journey to an Unprocessed Life  Week 10 Summary: Microbiome Mastery in a Doctor's 52-Week Unprocessed Life Journey Dr. Brent W. Laartz Reflects on Paris trip (high steps, fiber via fruits/salads, minimal supplements). Focuses on **microbiome week**: Gut bacteria's role in health/longevity; impacts from ultra-processed foods, red meat (e.g., colibactin-producing E. coli linked to colon cancer 10-20 years pre-diagnosis); promotes plant-based/Mediterranean/MIND diets. Discusses inflammation/leaky gut from poor microbiota (lipopolysaccharides entering blood); personal diet: 3-4 vegan days/week, minimal red meat/dairy (some cheese), low protein + resistance training for longevity/muscle preservation. Ties microbiome to **five pillars** (diet, movement, sleep, plastics, connection): Fiber/pre/pro/postbiotics produce short-chain fatty acids (SCFAs like butyrate/propionate) for gut health, fitness, sleep; exercise enhances SCFA benefits; alcohol disrupts good bacteria; fermented foods > probiotics. Debunks myths: Fiber not "anti-nutrient"; low-protein diets (e.g., isoleucine-deficient) extend mouse lifespan 20%; avoids gym bro high-protein/carnivore/keto fads. Recaps progress (week 10/52): Berries daily, accountability app tracking, supplements (B12, omega-3, D, calcium), steel/glass kitchenware, olive/avocado oils, no packaged foods goal. **Personal updates**: Cholesterol improved; plans re-test plastics in urine post-water bottle changes; 36-48h fast weekly. Key Points and Decisions **Microbiome Health Drivers**: - Avoid ultra-processed/red meat → reduce colon cancer risk (screening now at 40). - High fiber (psyllium, inulin, raw veggies/fruits/nuts/beans) → SCFAs → healthy colonocytes, no leaky gut, better fitness/sleep. - Fermented foods (hummus, yogurt, sourdough) for persistent bacteria. - Low protein + resistance training preserves muscle in aging. **Diet Decisions**: - 4-5 vegan days/week (aim 6 by year-end); raw veggies/fruits/nuts/beans 3x/week; homemade hummus/beans; 40+ whole foods variety (berries/pineapple only fruits); 100% vegan attempt this week. - No red meat/dairy (cheese exception); beans 3x/week; 2 tbsp psyllium daily; more water. **Other Pillars**: - **Movement**: 20k steps goal (10k min); racket sports 1x/week (tennis for impact/upper body/connection); dog walks; resistance training. - **Sleep**: Rose-Thorn-Bud meditation (reframe negatives), 4-7-8 breathing, blackout room/mask. - **Connection**: Music class (Khan Academy), learn guitar/saxophone, poetry/painting, reconnect old friends (Thursday Throwback), language apps (French/Spanish/Italian). - **Plastics**: Stainless/glass pet bowls; PVA-free laundry tablets; bamboo toothbrush/toothpaste tablets; glass water dispenser. - **Fasting**: 36-48h weekly for autophagy/insulin reduction. Next Steps **Diet**: Hit 40 whole foods; 5 vegan days/week long-term; raw cashews; expand bean variety (black beans/rice). **Movement**: Racket sports (tennis courts field trip week 11); maintain running/resistance; dog walks early AM. **Sleep**: Daily Rose-Thorn-Bud + 4-7-8; better blackout/mask. **Connection/Creativity**: Khan Academy music class; instruments (bass guitar, sax); Friday poetry, Monday meditation video. **Testing/Monitoring**: Re-test cholesterol/apoB/Lp(a); plastics in urine after non-plastic water switch. **Podcast**: Week 11 field trip (tennis demo, high-impact workouts for longevity); book release post-52 weeks. **Accountability**: App tracking (vegan, greens/berries, exercise, fasting, beans/ferments, no sugar/soda/packaged).

    1h 17m
  5. Apr 27

    Week 9: A Doctor's 52 Week Journey to an Unprocessed Life

    Week 9: A Doctor's 52 Week Journey to an Unprocessed Life Week 9 Summary: Dr. Brent Laartz's Unprocessed Journey – Paris Travel Edition  Summary by Speaker  Dr. Brent Laartz  *Travel Edition (Paris/France)**: Week 9 update; praises French culture, food (organic markets, berries, strawberries, chocolate), architecture; notes smoking culture among youth.   **5 Pillars Challenges/Adaptations**: - **Diet**: Mostly vegan (3-5 days/week), antioxidants (berries, dark chocolate), local produce; avoids fake meats/cheeses; plans crepes/hot chocolate (dairy-free); less alcohol, zero-alc options. - **Movement**: High activity (25k steps/12 miles walking, 4-mile run); preps with prior training to avoid injury; prefers walkable areas, run clubs, hiking; avoids Ubers. - **Sleep**: Jet lag prep (dark room, morning light, advance clock, avoid caffeine/plane sleep); cooler room, weighted blanket. - **Connection**: Meets locals/expats (college friend, run clubs, cafes, small tours, French classes like "French as You Like It"); avoids tourist traps/Americanized spots. - **Plastics/Chemicals**: Organic shops for soaps/lotions; glass water bottles (Evian); avoids hotel plastics.  **9-Week Progress Recap**: Weight loss, better cholesterol/HbA1c (ex-pre-diabetic); berries daily, Oura ring, meal prep, supplements (Ca/D/B12/omega-3), vegan shifts, low-carb/no artificial sugars, psyllium/fiber, homemade dressings, run clubs, non-plastic home, mindfulness.  **Personal Insights**: Stay true to local culture; health for longevity; self-worth key.  Key Points and Decisions  **Diet Decisions**: 3-5 vegan days (incl. travel); prioritize antioxidants/local organic (berries, dark chocolate); homemade dressings; poultry/seafood only if non-vegan; no fake vegan products.  **Movement**: 6 days/week training (cardio/resistance); vacation exceeds routine; prep to prevent injury; join Paris run clubs (walkers welcome).  **Sleep/Travel Hacks**: Blackout rooms, morning sunlight, clock advance, no afternoon caffeine.  **Connection**: Local immersion (cafes, small tours/classes, expats); family cultural exposure.  **Avoidances**: Plastics/chemicals (glass/stainless, organic products); processed foods/oils; non-stick pans; red meat/dairy excess; Ubers when possible.  **Health Wins**: Improved metrics despite family diabetes risk; extended fasting.  Next Steps  Meet college friend in Paris (possible walk/Uber).  Join Paris run clubs (20+ options).  Take French class ("French as You Like It").  Continue 3-4 vegan days; eat crepes/dairy-free hot chocolate.  Weekly Zoom calls; follow/share on gonopro.com, social media (TikTok, Instagram, Facebook, Threads, Substack, YouTube/Spotify/Apple video podcasts; Brent Williams Larson MD).  Sustain pillars for longevity; audience input welcome.

    30 min
  6. Apr 20

    Sunday Science Testosterone 2026_04_19

    Sunday Science: Testosterone Therapy – Risks, Benefits & Longevity Debate Summary by Speaker Dr. Brent Laartz Discusses testosterone decline with age (0.4-2.6%/year, 30-50% by 50-60), low T ( Reviews studies: - Low T associated with 1.5-2.3x higher all-cause, CV, cancer mortality (2010 European Heart Journal cohort; 2011 JCEM meta-analysis). - Frailty mediates 35% of low T mortality risk. - Eunuch/castration studies (Korea, Poland, animals): 10-20% longer lifespan, but pre-puberty vs. late-life low T. - TRT studies: Decreased mortality if levels normalized (2012, 2015 European Heart Journal cohorts); short-term (3 years) benefit; non-normalized TRT no benefit. Notes biases in cohorts (healthy user effect); no RCTs yet. Emphasizes N=1 individualized approach considering personal risks (e.g., prostate/heart disease). Key Points and Decisions **Low Endogenous Testosterone**: Strongly linked to higher mortality (all-cause, CV, cancer); associated with frailty, metabolic issues. **Castration/Eunuch Data**: Suggests lifelong low T may extend life, but not directly comparable to adult TRT. **TRT Evidence**: Cohort studies show mortality reduction with normalized levels (esp. long-term), but short-term CV risks possible; no definitive RCTs. **No Firm Decisions**: Informational only; no endorsements for/against TRT; highlights need for RCTs to resolve controversy. Next Steps **Research**: Await randomized controlled trials (RCTs) for definitive TRT mortality data. **Individuals**: Check testosterone/health markers regularly (yearly+); consult physicians for personalized risks/benefits; prioritize resistance training, healthy lifestyle. **Audience**: Seek professional medical advice; follow show on YouTube, Spotify, Apple Podcasts, social media, goonpro.com.

    23 min
  7. Feb 9

    Sunday Science 2026_02_08

    Summary of Key Points, Decisions, and Next Steps by Speaker Dr. Brent Laartz Key Points and Decisions: Discussed several recent studies on the association between playing professional sports, particularly American football, and longevity. Highlighted the Copenhagen City Heart Study, which showed that different sports, such as tennis and badminton, can add years to one's life. Reviewed studies on elite athletes, noting that endurance sports and team sports tend to have better longevity outcomes compared to power sports. Discussed a recent study in the British Medical Journal that explored the relationship between the variety of physical activities and mortality, suggesting that a diverse range of sports may be beneficial for longevity. Next Steps: Encourage a variety of physical activities, including both cardiovascular and strength-based exercises, as well as sports that involve balance, cognitive demands, and social engagement. Emphasize the importance of finding the right balance, as too much exercise may not necessarily be better than a moderate amount. Promote the benefits of recreational sports, such as tennis and badminton, in addition to more traditional endurance activities. Explore the potential role of hormesis, where moderate levels of stress (e.g., exercise) can be beneficial, but too much may be detrimental. Encourage further research to better understand the complex relationship between physical activity, sport participation, and longevity.

    43 min

About

Go Un-Pro with Dr. Brent W. Laartz, MD FIDSA: Living an Unprocessed Life for Longevity and Healthspan Have you ever known that something is SO good for you that you just can't wait, but life gets in front of you and prevents you from doing it? The inaction and procrastination could occur for a variety of reasons, and we will delve into my motivations and affirmations of a healthy life from this day forward. I am starting this series of videos and articles so that I can be accountable to myself regarding the changes in my diet that I REALLY NEED to survive into my 90s without heart disease, dementia, and arthritis. And hopefully, as you follow along, you can make your own improvements that will extend your life and prevent the horrible illnesses that are heart disease, dementia, and arthritis. Can I introduce myself? I'm Dr Brent W. Laartz, and I am an Infectious Diseases physician with a Master's in Neuroscience, author, creator, and entrepreneur. I've been involved with medical education for almost all my life and have been sharing my knowledge, teaching students, patients, and other doctors as faculty of a medical school, in hospitals, and clinics around the world. I'm ashamed to admit that I have lived a life of processed foods despite knowing the facts that are stacked against me if I continue living this way. My most recent research into longevity and its connection to our diet, exercise, sleep, and mental health, all with help from our microbiome, the bacteria living in our body, has me wanting to shout this information to the masses from the rooftops! This is so important that I am going to communicate what I have learned in every forum possible. Simply put, I am not going to do it anymore, and I am going to stay accountable to myself so that I follow through with it this time. Hence, the launch of this podcast, which I have been wanting to do for quite some time now. In addition, I am also launching publicly available Master courses that will delve incredibly deeply into the science behind diet and other interventions that will help me live well into my '90s and 100s, but not just live, but REALLY live! This is the concept of Healthspan. I know there are a lot of billionaires who are prominent in the media, trying to live forever, spending millions of dollars, but I am here to prove you can do it without spending a lot of money. The interventions I am doing will cost a little more money, but my budget is to only increase expenditures by a few $100 a month. The thing is, we are so accustomed to our artificial products that we deep down believe they are good for us. Don't accept this BS from your food, expect better. Most physicians I know are not living a healthy life, and until the past 6 months, that generalization included me. If you think otherwise, let me paint the picture of a typical doctor's lounge in the hospital or the home kitchen of your local physician. Hospital kitchens use the cheapest oils, fried foods, and beef, butters with mashed potatoes, pre-manufactured eggs, mass-produced bacon, candy, and ice cream sandwiches. This is what I was eating day in and day out, working 26 days per month. My cholesterol was skyrocketing, and my weight had peaked at 165 pounds on a 5-foot-7-inch frame. Then I took stock of my life. And it was just in time, too, for my kids were graduating from high school. At least I didn't have the excuse of cleaning my kids' plates anymore. I suspect that if you are listening to this podcast, reading this article, or taking this course, you are interested in living a more unprocessed life. If you are like me, you have reached a point in your life where you realize your health could be at a tipping point. I was lulled into thinking I was living a healthy life because I exercised and ate right some of the time. But that delusion could not have been further from the truth. I was drinking alcohol at least a few days per week, drank sodas at least a few days a wee