Forever Young

Forever Young

Sharing the science of longevity with a healthy dose of humanism. Helping you cut through the noise and explore our species' deepest fears, greatest hopes, and wildest dreams. foreveryoungfilm.substack.com

  1. 15h ago

    Move Better, Age Better: Fitness for Longevity with Jill Dailey

    In 2000, Jill Dailey opened the first barre studio on the West Coast. She grew The Dailey Method into more than 60 studios, and she still teaches almost every day. Her longest-standing students are in their seventies and eighties, and they often credit her class for their long-term mobility. What we cover: * Why alignment comes before strength, and what the small stabilizing muscles do that the mirror muscles cannot * The hinge lunge, demonstrated with progressions from holding the barre to lifting 25 pounds. Falls are the leading cause of injury death among adults 65 and older, and the CDC classifies most of them as preventable * The three movements Jill recommends at any age: the plank, the hinge lunge, and the deep turned-out squat * Why transitions between positions cause more injuries than the exercises themselves * How varied, unpredictable movement supports the aging brain * Building 60+ studios while raising three kids * What aging asks of women, and why community keeps people training for decades * The two words that carried her through all of it This conversation is for general information and is not medical advice. A physician can help tailor any new exercise program to your health history. Keep going: Jill teaches in person and online. Her studios, virtual classes, and programs are at thedaileymethod.com and daileymethodonline.com. Haven’t seen our award-winning documentary yet? Click here to watch Forever Young on a platform of your choice. Want longevity news sent directly to your inbox? Sign up for our weekly newsletter. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

  2. Aug 11

    Epigenetic reprogramming reaches humans, how other people keep us alive, and the memory slip everyone misreads

    In our film Forever Young, Ava receives an annual epigenetic treatment and leaves the clinic a year younger than she arrived. We wrote that as fiction. In June, Life Biosciences dosed the first human being with a partial epigenetic reprogramming therapy. This is just one of many topics covered in our AMA with Dr. Thomas Lewis. Dr. Thomas Lewis is a psychiatrist and neuroscientist, co-author of A General Theory of Love, and a co-star and producer of the film. You sent the questions. He answered. Two notes on accuracy The reprogramming trial discussed is a Phase 1 safety study run by Life Biosciences, which David Sinclair co-founded. The FDA cleared the application in January 2026, and the first participant was dosed on June 9. Clearance to begin a trial is not approval of a therapy. On dementia genetics, Dr. Lewis describes research showing no genetic difference in people highly resistant to cognitive decline. That reflected the literature when he learned it. The largest study to date, published in January 2026 across 18,080 participants, found such people were 19 percent less likely to carry the APOE-e4 variant. His broader point holds. Genetics accounts for far less of dementia risk than was assumed a decade ago, though it is not absent. The longevity revolution is moving fast. Don’t fall behind. Join the readers who want the full picture → Forever Young is streaming worldwide. Haven’t watched it yet? Click below to pick your platform. Sources Nothing here is medical advice. Evidence suggests several of the interventions discussed may support healthspan, and each one should be discussed with your physician before you act on it. Leone M, Barzilai N. An Updated Prioritization of Geroscience-Guided FDA-Approved Drugs Repurposed to Target Aging. Medical Research Archives. 2024;12(2). Durant A, et al. Evaluating the association of apolipoprotein E genotype and cognitive resilience in SuperAgers. Alzheimer’s & Dementia. 2026;22(1). Newman SJ. Morbid: Debunking Modern Longevity Science. 2026. Lewis T, Amini F, Lannon R. A General Theory of Love. Random House, 2000. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    Epigenetic reprogramming reaches humans, how other people keep us alive, and the memory slip everyone misreads
  3. Mar 22

    Love, Longevity, and the Wellness Trend He Calls a Total Scam — Dr. Eric Verdin, Unfiltered

    Dr. Eric Verdin is one of the scientists at the heart of our award-winning documentary Forever Young. He’s also president and CEO of the Buck Institute for Research on Aging. After a private screening of the film, director David Donnelly sat down with Verdin for a live virtual Q&A with the audience. No talking points. Just an hour of unfiltered conversation with one of the most respected minds in longevity science. In this conversation, Verdin reveals: * The longevity variable most people completely overlook — and why he’s building an entire research center around it * Why your outlook on life isn’t just a mood issue — and what the science says it’s actually doing to your body * On the realities of GLP-1 agonists, V02 max, and other topics that have captivated popular culture * The booming wellness trend he calls a total scam — and why it makes him furious every time he walks past one Plus: what’s actually coming in anti-aging medicine, the real science on fasting, and what an approved longevity drug could look like within five years. This is just the beginning. Dr. Verdin mentioned something in passing that most people don’t fully register: the biology of aging can be modulated. One of the most extraordinary examples of that happening right now is at his own institution — the Buck Institute’s work on senescent cells, the so-called “zombie cells” that accumulate in your body as you age, quietly driving inflammation, accelerating disease, and shortening your life. Scientists now have drugs that can selectively eliminate them. In animal models, the results are extraordinary. Paid subscribers get access to that interview as well as our full archive of 100+ videos and articles that give insider access to the drugs, treatments, science, and philosophy driving the most exciting revolution of our lifetime. The longevity revolution is moving fast. Don’t fall behind. Join the readers who want the full picture → This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit foreveryoungfilm.substack.com/subscribe

    Love, Longevity, and the Wellness Trend He Calls a Total Scam — Dr. Eric Verdin, Unfiltered

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Sharing the science of longevity with a healthy dose of humanism. Helping you cut through the noise and explore our species' deepest fears, greatest hopes, and wildest dreams. foreveryoungfilm.substack.com