The Business Of Neurotech

Adam Fraser

From breakthrough devices to the bottom line. The Business of Neurotech is the premier podcast dedicated to the commercial trends, investment strategies, and innovative business models shaping the neuroscience economy. Hosted by Adam Fraser, this series moves beyond the lab to explore how groundbreaking research in neuromodulation, BCI, and medical devices is transformed into viable, scalable enterprises. +2 Each episode features candid, fireside-chat interviews with the ecosystem's most influential voices—from founders and CEOs to venture capitalists and strategic leaders. We dive into the "how" and "why" behind the headlines, discussing market maturity, regulatory hurdles, and the go-to-market strategies required to bring neurotechnology to the global stage. +3 Whether you are an investor conducting due diligence, a researcher exploring commercial applications, or an entrepreneur building the next generation of brain-tech, this show provides the strategic insights you need to navigate the future of the sector.

  1. 2d ago

    Chay Carter Talks Neurotech Recruitment and Market Trends

    What can the people building neurotech teams tell us about where the industry is heading? In this episode of The Business of Neurotech, Adam Fraser speaks with Chay Carter, founder of Carter Sciences and co-founder of reccy neuro, to offer a recruitment-focused view of the sector. Chay brings decades of experience in recruitment and psychology, combining specialist hiring with research, newsletters and insights from the people developing the technology. In their conversation, Chay shares how he came to focus on neurotech and what he has learnt about helping companies build the teams they need. They also discuss the influence of AI on recruitment, the broader trends he is seeing across neurotech and how his research and media work connect with the changing needs of the industry. Tune in for Chay’s perspective on people, relationships and how the market is shaping neurotech’s next chapter. Key Points From This Episode: [01:24] Trace how Chay’s career led to specialist neurotech recruitment and reccy neuro.[07:37] Discover what makes a strong founding team beyond scientific and technical talent.[09:39] Learn how hiring priorities change as startups move towards commercialisation.[12:03] Understand why big-company experience can be a shock to the system at a startup.[13:59] Explore how market trends shape his recruitment and fractional support for startups.[18:39] Examine where AI, BCI, and implantable devices are changing the demand for talent.[21:07] Hear why AI applications and screening still require real human conversations.[23:46] Consider whether AI can replace the hands-on work neurotech companies need.[25:24] Follow how Chay transforms global news into newsletters, interviews, and deep dives.[29:26] Unpack the scale and pace of neurotech’s growth and difficulties defining the sector.[31:50] Assess how his media and market data could become a business in their own right.[34:53] Compare US dominance with the neurotech activity happening around the world.[38:04] Find out why wearable brain-reading devices still face a form factor challenge.[39:05] Connect with Chay and access his research and free neurotech company database.Links Mentioned in Today’s Episode: Chay Carter on LinkedIn Carter Sciences  reccy neuro Carter Sciences | The Neurotech Newsletter  The Open Loop Podcast Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

  2. Oct 5

    Paul Le Floch talks BCI, Coma and Start Up Dynamics

    How can softer materials make implantable brain-computer interfaces safer, more stable and clinically useful? In this episode of The Business of Neurotech, Adam Fraser is joined by Dr Paul Le Floch, co-founder and CEO of Axoft, to explore how his materials science background led to Fleuron, a soft neural interface platform designed to reach deep brain regions while maintaining high-density recordings. Dr Le Floch explains why Axoft is initially focusing on disorders of consciousness, how the company is taking a stepwise path through FDA clearance and what its early clinical work revealed about turning novel biomaterials into medical devices. He also discusses the realities of raising a $55 million Series A, competing in a fast-moving BCI market, financing research through materials sales and learning to pitch a long-term vision as a scientist-founder. Tune in to learn what it takes to build an invasive BCI company focused on better materials, unmet clinical needs and patient impact. Key Points From This Episode: [01:29] Dr Le Floch’s path from materials science at Harvard to founding Axoft.[03:21] Discover why the brain’s electrical complexity drew him into neuroscience.[04:57] Unpack how Fleuron’s softness aims to improve compatibility with brain tissue.[06:44] Explore why stable neural data links efficacy with reduced tissue disruption.[08:58] Compare invasiveness with signal quality and where Axoft sits on that continuum.[12:19] Find out why disorders of consciousness became Axoft’s first clinical focus.[16:26] Follow the roadmap from diagnosis and prognosis towards decoding communication.[18:12] Understand Axoft’s stepwise regulatory strategy for a temporary inpatient device.[20:15] He shares his experience working with the FDA in an emerging BCI category.[21:34] Uncover the clinical evidence and commercial plan behind Axoft’s Series A.[23:25] The clearance, manufacturing and clinical milestones needed for Series B funding.[25:14] Gain insight into why BCI’s difficult venture capital environment is still worth the risk.[28:47] Unpack Axoft’s strategy in a field of well-funded but complementary competitors.[30:12] Hear how materials sales fund research while providing partnership opportunities.[33:35] Why targeted stimulation that bridges devices and drugs is capturing his attention.[35:11] Learn how scientist-founders can move from research to vision-led application.[37:18] Final takeaways and how to learn more about Axoft and Dr Le Floch’s work.Links Mentioned in Today’s Episode: Dr Paul Le Floch on LinkedIn Axoft Axoft on LinkedIn Episode 5: Naveen Rao Talks Neurotech Market Dynamics Episode 8: Nicolas Vachicouras Talks BCI Market Dynamics and Start Up Life Episode 12: Matt Angle Talks Paradromics and BCI Market Dynamics Mass General Brigham FDA Breakthrough Devices Program iBCI Collaborative Community (iBCI-CC) Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

  3. Sep 21

    Jordan DeKraker Talks Seed Funding, Brain AI and Epilepsy

    How can academic brain-imaging research become a practical clinical tool for people with drug-resistant epilepsy? In this episode of The Business of Neurotech, Adam Fraser is joined by Jordan DeKraker, co-founder and CEO of BrainScores and a postdoctoral researcher at the Montreal Neurological Institute, to discuss how he went from hippocampal mapping to building an AI-enabled neuroimaging company. In their conversation, Jordan talks about how his personal experience with epilepsy sharpened the company’s focus, what it takes to package open-source science into trustworthy software and why clinicians still need to stay in the loop. They also discuss early-stage funding, regulatory and market-entry decisions, interoperability, explainable AI and the wider role of precision imaging across neurotech. Tune in for a look at the business decisions behind bringing brain AI from the lab into clinical care with Jordan DeKraker. Key Points From This Episode: [01:21] Jordan’s path from hippocampal research to founding BrainScores.[05:08] Find out what HippUnfold revealed and why its potential matters.[07:25] Hear how Jordan’s epilepsy experience shaped the company’s first focus.[12:05] Meet the co-founders and see how their skills support the company’s vision.[13:43] Examine BrainScores’ non-dilutive funding and ambitions for venture capital.[15:19] Understand the software as a medical device model and its go-to-market plan.[17:46] Learn how BrainScores is testing the market and the role of feedback from clinicians.[19:53] Uncover what the company hopes to achieve with its open-source platform. [23:17] Understand why clinicians must remain accountable within an AI-assisted workflow.[25:33] Whether healthcare AI should augment expertise rather than replace it.[27:24] The model interoperability needed to integrate various data sources and tools.[31:21] Compare funding, capital and opportunities between Canada and the US. [34:45] Explore BrainScores’ roadmap beyond epilepsy into age-related cognitive decline.[36:29] He shares his view on the future of BCI and transcranial stimulation. [38:10] Where to follow Jordan’s research and the latest work from BrainScores. Links Mentioned in Today’s Episode: Jordan DeKraker on LinkedIn The Neuro (Montreal Neurological Institute-Hospital) BrainScores BrainScores on LinkedIn McGill University HippUnfold The Human Connectome Project (HCP) Healthy Brains for Healthy Lives Centre for Aging + Brain Health Innovation Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

  4. Sep 7

    Matt Angle Talks Paradromics and BCI Market Dynamics

    For people who have lost the ability to speak, brain-computer interfaces (BCIs) could open a new path back to communication. In this episode, Adam Fraser speaks with Matt Angle, founder and CEO of Paradromics, about the company’s 11-year journey to build a BCI that can restore communication for people who have lost it. Matt explains why moving more neural data is central to BCI performance and how Paradromics is approaching safety, durability and clinical translation. He breaks down why speech restoration is the company’s first clinical focus, then unpacks what could come next, including movement applications, mood biomarkers and AI-enabled communication. The conversation also explores the company’s move from Silicon Valley to Austin, Texas, as well as the regulatory, reimbursement, funding and commercial realities of building in deep tech, and what it takes to turn frontier neuroscience into a durable company. Listen in for a closer look at Paradromics’ journey and the technology, capital and strategic thinking shaping the future of BCI. Key Points From This Episode: [01:31] Discover how Matt’s neuroscience background led him to found Paradromics.[03:18] Learn how BCI has shifted from pure science to an engineering challenge.[04:53] Hear why Matt has stayed in the CEO role 11 years into the journey.[07:34] Understand Paradromics’ focus on safety, durability and neural data.[08:29] Why moving more neural data is central to building better BCI systems.[14:00] Learn why speech restoration is Paradromics’ first clinical focus.[15:20] Explore the broader medical applications Paradromics may pursue next.[20:11] Find out why Paradromics moved from Silicon Valley to Austin, Texas.[22:25] Matt’s perspective on FDA engagement, regulation and reimbursement pathways.[27:26] Explore how Paradromics thinks about funding, competition and investor alignment.[33:28] Hear Matt’s view on IPO potential and the wider BCI ecosystem.[35:18] Why “invasive” is not always the best way to assess BCI risk.[39:29] Matt’s advice for founders building deep tech companies. Links Mentioned in Today’s Episode: Derrick Matthew Buchanan on LinkedIn Canada Neuro Royal World Archive Derrick Buchanan, Ph.D. Clinical Neuroscience  ‘The complex landscape of TMS devices: A brief overview’ ‘A visual and narrative timeline of US FDA milestones for Transcranial Magnetic Stimulation (TMS) devices’ ‘Should rTMS be considered a first-line treatment for major depressive episodes in adults?’ ‘Stanford neuromodulation therapy for treatment-resistant depression: a randomized controlled trial confirming efficacy, and an EEG study providing insight into mechanism of action and a potentially predictive biomarker of efficacy’ ‘Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression’ Matt Angle on LinkedIn Paradromics Paradromics | Connexus Matt Angle on Substack ‘CMS and FDA Announce RAPID Coverage Pathway to Accelerate Patient Access to Life-Changing Medical Devices’ Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

  5. Aug 24

    Derrick Buchanan talks Stanford, Transcranial Magnetic Stimulation and Neurotech

    Brain stimulation is moving from specialist clinics towards faster, more personalised and scalable care. In this episode, Adam Fraser speaks with Dr Derrick Buchanan, a clinical neuroscientist in Stanford’s Brain Stimulation Lab, entrepreneur, author and speaker whose work spans precision brain imaging, neuromodulation and mental health. Derrick discusses his path from Canada to Stanford and explores how the university turns research into companies. He unpacks how transcranial magnetic stimulation works, why adoption still lags behind its clinical promise, and where portable devices may take the field. They also explore the neurotech ecosystem and the long-term investment logic behind BCI. Tune in to hear how science, commercialisation and access could shape the next generation of brain care with Dr Derrick Buchanan. Key Points From This Episode: [01:50] Discover how Dr Buchanan’s career path shaped his work and entrepreneurship.[09:22] Explore what makes Stanford the ideal place for cutting-edge research.[11:56] Unpack how Stanford handles IP, licensing and startup ownership.[16:16] Learn how transcranial magnetic stimulation (TMS) stimulates the brain.[23:30] Uncover the barriers holding back the wider adoption of TMS.[28:29] Find out how portable TMS could expand access and when to expect it.[31:09] Hear his perspective on applying neurotech across imaging, stimulation and BCI.[34:28] Dr Buchanan explains how invasive and non-invasive tools can coexist.[38:31] Final takeaways and why investors are betting heavily on BCI.Links Mentioned in Today’s Episode: Derrick Buchanan  Derrick Buchanan on X Stanford Medicine The Brain Stimulation Lab (BSL)  Canadian Institutes of Health Research Stanford Office of Technology Licensing Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT) Motif Neurotech Episode 6: David Eagleman Talks Media, Startups, and Neuroscience Episode 4: Mariam Khayretdinova talks EEG, AI and Psychiatry Adam Fraser on LinkedIn  Omniscient Neurotechnology  The Business of Neurotech Podcast

  6. Aug 10

    Matias Serebrinsky talks frontier brain and mental health VC investing

    What makes an emerging technology bold enough and a founder exceptional enough to justify taking an early-stage risk? In this episode of The Business of Neurotech, Adam Fraser sits down with Matias Serebrinsky, Founding Partner at PsyMed Ventures, a specialist venture capital fund investing in frontier brain and mental health technologies. Matias brings a dual perspective as both a former startup founder and an early-stage investor who previously supported AI companies during a pivotal period in the industry’s growth. In this conversation, he reflects on how breakthrough technologies move from research labs into real-world products and what it takes for scientific drive to become a venture-scale company. They also discuss the evolution of neurotechnology as an investment category, the realities of backing high-risk frontier science, and how PsyMed assesses early-stage opportunities across brain-computer interfaces, neuromodulation, mental health innovation and more. Tune in for an investor’s view of the people and technologies driving frontier neuro forward. Key Points From This Episode: [01:15] Explore Matias’ journey from startup founder and NVIDIA to neuro investing.[05:37] Uncover the three qualities PsyMed looks for in an early-stage investment.[06:54] Explore Matias’ broad definition of neurotech and the market behind it.[08:30] He shares PsyMed’s approach to investing early and supporting founders.[12:55] Whether specialist and generalist funds will grow as more investors join.[15:35] Consider what major exits could mean for neurotech’s investment appeal.[18:54] Learn which opportunities are currently capturing PsyMed’s attention.[22:18] Hear about a BCI company taking a different path to developing neurotech.[28:34] Discover the role capital plays in turning science into a successful company.[30:58] Unpack the different hardware approaches to neuromodulation. [34:15] Understand what changes when a wellness product enters medical territory.[36:28] Matias’ advice for researchers considering the startup journey.Links Mentioned in Today’s Episode: Matias Serebrinsky on LinkedIn PsyMed Ventures PsyMed Ventures on Substack Business Trip Podcast ‘The State of Frontier Neuro’ Motif Adam Fraser on LinkedIn  Omniscient Neurotechnology  The Business of Neurotech Podcast

  7. Jul 27

    Richard Mulry Talks Health System Venture Capital and Neurotech Investing

    How do you turn promising neurotechnology into solutions that can actually work inside healthcare systems? In this episode of The Business of Neurotech Podcast, Adam Fraser is joined by Richard Mulry, President and CEO of Northwell Holdings, the for-profit venture investment arm of Northwell Health, to explore what it takes to identify, invest in, and scale innovation in clinical care. Richard explains why Northwell prefers to invest in companies it would use itself, and how clinical evidence, workflow integration, and strong partnerships shape every investment decision. The conversation explores the unique opportunities and challenges of neurotechnology, from brain-computer interfaces (BCIs) and neurorehabilitation to AI-enabled platforms and bioelectronic medicine. Richard also shares why solving meaningful clinical problems matters more than following investment trends, how strategic healthcare investors can help companies prove real-world value, and what founders should know about working with strategic investors. Listen in for an insightful discussion on what it takes to bring neurotechnology from concept to clinical impact! Key Points From This Episode: [01:28] Richard’s career in healthcare and his path to Northwell Holdings.[04:32] Background on Northwell and its approach to healthcare innovation.[07:15] Discover Northwell's investment process and selection criteria.[11:25] Why Northwell prefers to invest in companies it would use itself.[12:30] Find out how Northwell complements traditional venture capital investors.[16:46] Understand Richard’s perspective on the neurotech market.[19:29] Hear why Northwell invested in Cognixion and its evolving platform.[21:43] Explore Northwell’s view of invasive versus non-invasive BCIs.[26:36] Learn about Northwell’s latest neurotech investments.[31:31] Understand how Northwell supports companies through FDA and reimbursement.[32:50] Discover how AI is reshaping healthcare operations and medtech.[37:03] Richard’s advice for founders seeking strategic investors.[39:33] Final takeaways and how to connect with Northwell Holdings.Links Mentioned in Today’s Episode: Richard Mulry on LinkedIn Northwell Holdings Northwell Holdings on LinkedIn Northwell Health Northwell Health on LinkedIn Feinstein Institutes for Medical Research | Northwell Health Cognixion Neuvotion Spark Biomedical OhmBody SetPoint Medical Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

  8. Jul 13

    Nicolas Vachicouras Talks BCI Market Dynamics and Start Up Life

    What does it take to build a BCI company around better hardware, stronger data, and a long-term view of how the brain will be decoded? In this episode of The Business of Neurotech, host Adam Fraser is joined by Nicolas Vachicouras, CEO and co-founder of Neurosoft Bioelectronics, to discuss his path from microelectronics and nanotechnology into the BCI space, and how Neurosoft is developing soft, stretchable electrodes designed to sit on the brain surface rather than penetrate it. Adam and Nicolas discuss the technical and commercial thinking behind Neurosoft’s strategy, how the company has moved from early academic work to first-in-human studies, and why platform thinking now matters more than pursuing a single indication. They also discuss fundraising in Europe versus the US, why BCI still needs high-quality invasive data to unlock future breakthroughs, how the partnership with Science Corp fits into the wider BCI value chain, and why Nicolas believes the field will likely support several major players over time. Tune in now! Key Points From This Episode: [01:25] Nicolas’ backstory and how his studies led him into BCI.[03:17] See how Nicolas first started thinking about commercialising neurotechnology.[05:56] Explore what Neurosoft is building and the core idea behind its approach to BCI.[07:43] Understand how Neurosoft’s approach differs from typical BCI technology.[09:17] The different levels of invasiveness in BCI and how this impacts data quality.[11:38] Neurosoft’s progress and how the roadmap to clinical trials is taking shape.[15:15] Learn how Neurosoft’s focus has evolved from tinnitus towards a broader strategy.[17:40] Find out whether mental health is part of Neurosoft’s long-term plan.[18:52] Unpack Neurosoft’s funding journey and what Nicolas has learnt along the way.[21:19] Discover why Neurosoft is starting with the US market, instead of Europe.[22:28] Why funding in a market where competitors have more capital is not an issue.[24:00] Examine how the partnership with Science Corp fits into Neurosoft’s long-term goals.[28:27] How BCI fits into the broader neurotech ecosystem and the future market of BCI.[30:59] Uncover why reimbursement remains such an important challenge for BCI.[32:39] Hear how Nicolas thinks about building a team for a long-term goal. [36:14] Final takeaways and how to connect with Nicolas and Neurosoft Bioelectronics.Links Mentioned in Today’s Episode: Nicolas Vachicouras Nicolas Vachicouras on LinkedIn Neurosoft Bioelectronics Science Corp Adam Fraser on LinkedIn Omniscient Neurotechnology The Business of Neurotech Podcast

Ratings & Reviews

5
out of 5
2 Ratings

About

From breakthrough devices to the bottom line. The Business of Neurotech is the premier podcast dedicated to the commercial trends, investment strategies, and innovative business models shaping the neuroscience economy. Hosted by Adam Fraser, this series moves beyond the lab to explore how groundbreaking research in neuromodulation, BCI, and medical devices is transformed into viable, scalable enterprises. +2 Each episode features candid, fireside-chat interviews with the ecosystem's most influential voices—from founders and CEOs to venture capitalists and strategic leaders. We dive into the "how" and "why" behind the headlines, discussing market maturity, regulatory hurdles, and the go-to-market strategies required to bring neurotechnology to the global stage. +3 Whether you are an investor conducting due diligence, a researcher exploring commercial applications, or an entrepreneur building the next generation of brain-tech, this show provides the strategic insights you need to navigate the future of the sector.

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