Dr. John Campbell

Campbellteaching

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

  1. 46m ago

    Comparative immunity update

    High infection rates in UK, going down in US https://www.telegraph.co.uk/news/2021/10/19/people-must-cautious-day-to-day-interactions-covid-cases-climb/ Lower functional immunity in our population than most other Western European countries Early vaccine roll out AstraZeneca protects slightly less well than Pfizer against infection and transmission, particularly delta variant Slightly lower overall vaccination coverage, particularly vaccinating teenagers Fewer social restrictions High rates of testing UK, ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights Two vaccine doses give similar protection as previous infection Two doses of either Pfizer-BioNTech or Oxford-AstraZeneca Provided a similar level of protection as having had a previous natural infection of coronavirus During delta variant times Vaccination reduced the risk of testing positive, both when the alpha variant was dominant in the UK (1 December 2020 to 16 May 2021) and when the delta variant was dominant (17 May to 14 August 2021) Two doses of Pfizer-BioNTech Reduced the risk of testing positive by 73% in the delta period Two doses of Oxford-AstraZeneca Reduced the risk of testing positive by 62% in the delta period Two vaccination doses, more effective than one at preventing symptomatic infection in both periods. Three weeks after vaccination Two doses always more protective than one (75% v 58%) Inconsistent with covid symptom study https://covid.joinzoe.com/post/do-i-need-a-covid-vaccine-if-ive-had-covid Two doses of the Pfizer 87% protection against infection Two doses of the AstraZeneca 71% protection against infection Natural infection alone Only gave 65% protection against catching it again Israeli data consistent with ONS but inconsistent with covid symptom study Protection of previous SARS-CoV-2 infection is similar to that of BNT162b2 vaccine protection: A three-month nationwide experience from Israel https://www.medrxiv.org/content/10.1101/2021.04.20.21255670v1.full.pdf Vaccination was highly effective Estimated efficacy for documented infection of 92·8% Hospitalization 94·2% Severe illness 94·4% Death 93·7% Protection from prior SARS-CoV-2 infection Estimated efficacy for documented infection of 94·8% Hospitalization 94·1% Severe illness 96·4% All deaths registered in the week to 8 October COVID-19 deaths fall in England, Northern Ireland and Scotland Up in Wales Total UK deaths in the week, 12,490 14.7% above the average in 2015 to 2019 820 involved the coronavirus (COVID-19) 154 fewer than the previous week Deaths involving COVID-19, 1 in 15 deaths (6.6%). UK total deaths include non-residents. 1 million people in UK countries had COVID-19 in the latest week 1.63% in England (1 in 60 people) One in 70 people the week before 2.18% in Wales (1 in 45 people) One in 55 people the week before 0.82% in Northern Ireland (1 in 120 people) One in 130 people the week before 1.26% in Scotland (1 in 80 people) One in 60 people the week before Greg and Peter Hello John, Just to let you know that one of my posts referring to your video on aspiration has been pulled from LinkedIn. This is the first time that one of my posts has been pulled and I have put out some pretty controversial posts on other subjects. Feedback from vaccine manufacturers Learn more about your ad choices. Visit megaphone.fm/adchoices

  2. 1h ago

    Post viral syndrome information

    Long covid seems to be the same as any other post viral syndrome https://www.scimex.org/newsfeed/expert-reaction-long-covid-may-be-no-different-to-other-long-term-virus-effects From: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024, Barcelona, Spain, 27-30 April). Queensland data Long COVID ‘indistinguishable’ from other post-viral syndromes and other respiratory virus a year after infection Comparison with influenza and other respiratory illnesses Australia, Queensland, During Omicron wave No evidence of worse post-viral symptoms or functional impairment a year after infection. Long COVID may have appeared to be a distinct and severe illness because of high numbers of COVID-19 cases. N= 5,112 adult symptomatic individuals (Fatigue, brain fog, cough, shortness of breath, change to smell and taste, dizziness, rapid or irregular heartbeat) PCRs conducted between 29 May and 25 June 2022 PCR-confirmed infection for COVID-19 = 2,399 PCR negative for COVID-19 = 2,713 Influenza positive = 995 Results collected, May and June 2023 Overall Still reporting symptoms, 16% (834/5,112) Still reported moderate-to-severe functional impairment, 3.6% (184) Those still reporting any symptoms after a year Post Covid No difference Post Influenza Those with moderate-to-severe functional limitations a year after diagnosis None covid adults, 3% Covid positive adults, 4.1% Influenza positive adults, 3.4% https://bmjpublichealth.bmj.com/content/bmjph/1/1/e000060.full.pdf Comparison at 12 weeks post infection Ongoing symptoms after covid, 21.4% Ongoing symptoms after influenza, 23% Moderate to severe functional impairment after covid, 4.1% Moderate to severe functional impairment after influenza, 4.4% Obvious question not addressed!! Presence of spike protein antibodies Dr John Gerrard, Queensland’s Chief Health Officer These findings underscore the importance of comparing post-COVID-19 outcomes with those following other respiratory infections, and of further research into post-viral syndromes. Furthermore, we believe it is time to stop using terms like ‘long COVID’. They wrongly imply there is something unique and exceptional about longer term symptoms associated with this virus. This terminology can cause unnecessary fear Other commentators https://www.theguardian.com/society/2024/mar/15/long-covid-symptoms-flu-cold https://www.abc.net.au/news/2024-03-16/queensland-chief-health-officer-long-covid/103594020 https://www.9news.com.au/health/coronavirus-australia-queensland-health-study-long-covid/dede1234-d86f-4842-b6f9-975097dc7e62 Learn more about your ad choices. Visit megaphone.fm/adchoices

    Post viral syndrome information
  3. 2h ago

    WHO, YouTube and funding

    WHO and YT https://www.who.int/teams/digital-health-and-innovation/digital-channels/combatting-misinformation-online WHO works with social media policy departments to ensure company policy and guidelines for content providers are fit for purpose. John’s e mail enquiries@drjohncampbell.co.uk https://www.who.int/campaigns/connecting-the-world-to-combat-coronavirus/how-to-report-misinformation-online WHO provide a helpful guide on how to report misinformation online Inaccurate information spreads widely and at speed, making it more difficult for the public to identify verified facts and advice from trusted sources, such as their local health authority or WHO. https://support.google.com/youtube/answer/9795167?hl=en As a starting point in the UK, only NHS organisations are being invited to self-certify against the NHS Standard for Creating Health Content. By completing the self-certification process, an NHS organisation channel will be eligible for information panels indicating NHS credibility. From FDA to MHRA: are drug regulators for hire? https://www.bmj.com/content/377/bmj.o1538.full Regulatory agencies, large proportions of their budgets, funded by the industry they are sworn to regulate US Food and Drug Administration (FDA) 1992, Prescription Drug User Fee Act, allowing industry to fund the US Food and Drug Administration (FDA) directly through “user fees” Net PDUFA fees collected $29m in 1993 $884m in 2016 (65% of budget) FDA, 9 out of 10 of its past commissioners between 2006 and 2019 went on to secure roles linked with pharmaceutical companies European Medicines Agency (EMA) Industry fees funded 20% European Medicines Agency (EMA), in 1995 By 2010, 75% Today, 89% Medicines and Healthcare Products Regulatory Agency (MHRA) 86% of funding from Pharmaceutical Industry Australia https://www.tga.gov.au Proportion of TGA budget derived from industry, 96% WHO funding https://app.powerbi.com/view?r=eyJrIjoiNzNmNTRkMWEtNmZjMS00NzdjLWEyMDYtYWExYzA4NzVhZGQwIiwidCI6ImY2MTBjMGI3LWJkMjQtNGIzOS04MTBiLTNkYzI4MGFmYjU5MCIsImMiOjh9 https://www.weforum.org/agenda/2020/04/who-funds-world-health-organization-un-coronavirus-pandemic-covid-trump/ The second-largest funder is the Bill and Melinda Gates Foundation, which provides 9.8% of the WHO's funds Appendix https://genius.com/George-orwell-nineteen-eighty-four-appendix-the-principles-of-newspeak-annotated https://www.orwell.ru/library/novels/1984/english/en_app It was expected that Newspeak would have finally superseded Oldspeak (or Standard English, as we should call it) by about the year 2050 The purpose of Newspeak was not only to provide a medium of expression for the world-view and mental habits proper to the devotees of Ingsoc, but to make all other modes of thought impossible. The C vocabulary was supplementary to the others and consisted entirely of scientific and technical terms. These resembled the scientific terms in use today, and were constructed from the same roots, but the usual care was taken to define them rigidly and strip them of undesirable meanings. War is peace, freedom is slavery, ignorance is strength Next Monday, 14th November, evidence based medicine confrence https://www.eventbrite.co.uk/e/has-big-pharma-hijacked-evidence-based-medicine-tickets-444525075467 Learn more about your ad choices. Visit megaphone.fm/adchoices

    WHO, YouTube and funding
  4. 4h ago

    Long-term disease in children post-vaccination

    Henry Ford vaccine study. Senator Ron Johnson’s hearing, titled “How the Corruption of Science has Impacted Public Perception and Policies Regarding Vaccines,” https://live.childrenshealthdefense.org/chd-tv/events/committee-hearings/how-corruption-science-impact-public-perception-policies-vaccines/ After multivariate adjustment 57% of vaccinated children developed at least one chronic health condition (often multiple) 17% of unvaccinated children were chronically ill. Exposure to vaccination was independently associated with an increased risk of developing a chronic health condition (HR 2.53, CI 2.16-2.96). Exposure to vaccination Overall, the development of a chronic health condition occurred more often in the group exposed versus unexposed to vaccination. (p less than 0.0001) IRR 2.48, (CI 2.12-2.91). Risk independently associated with an increased risk of: Asthma HR 4.25, (CI 3.23-5.59) Autoimmune disease HR 4.79, (CI 1.36-16.94) Atopic disease HR 3.03, (CI 2.01-4.57) Eczema HR 1.31, (CI 1.13-1.52) Neurodevelopmental disorder HR 5.53, (CI 2.91-10.51) (mental health and neurodevelopmental disorders including developmental delay and speech disorder) Ear infection IRR 6.63, (CI 5.73-7.66) Chronic ear infection IRR 5.67, (CI 4.37-7.37) Anaphylaxis IRR 8.88, (CI 1.24-63.47) Asthma attack or bronchospasm IRR 6.30, (CI 3.85-10.31) There were no chronic health conditions associated with an increased risk in the unexposed group. Statistical comparisons could not be conducted for certain conditions, such as diabetes and ADHD, because there were no cases in the unexposed group. Ten years of follow up The overall probability of being free of a chronic health condition at 10-years of follow up: 43% in the group exposed to vaccination 83% in the unexposed group. (log-rank test, p less than0.0001) https://www.youtube.com/watch?v=RL5Zx1cIABo https://www.youtube.com/watch?v=Gh6r5rIo4Jw https://live.childrenshealthdefense.org/chd-tv/events/committee-hearings/how-corruption-science-impact-public-perception-policies-vaccines/ Committee on Homeland Security & Governmental Affairs (Search: Henry Ford vaccine study) PDF, entered into hearing records https://childrenshealthdefense.ca/news/henry-ford-birth-cohort-vax-vs-unvax-reveals-staggering-health-risks-in-vaccinated-children/ Impact of Childhood Vaccination on Short and Long-Term Chronic Health Outcomes in Children: A Birth Cohort Study Objective: To compare the short and long-term health outcomes, within a captured payer environment, of children exposed to one or more vaccines to those unexposed. Setting: Integrated healthcare system in Michigan. Participants: 18,468 children born between 2000 and 2016, enrolled in the health system insurance plan. Main Outcome Measures: Development of a chronic health condition over time. Results: 18,468 consecutive subjects 1,957 had no exposure to vaccination 16,511 had received at least one vaccine (various levels of exposure). In exposed subjects, the median number of vaccinations was 18 (IQR 2-28). Conclusion: This study found that exposure to vaccination was independently associated with an overall 2.5-fold increase in the likelihood of developing a chronic health condition, when compared to children unexposed to vaccination. This suggests that in certain children, exposure to vaccination may increase the likelihood of developing a chronic health condition, particularly for one of these conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Long-term disease in children post-vaccination
  5. 5h ago

    International omicron multiplication

    Link for free download of John's two text books, http://159.69.48.3/ Campbell's Pathophysiology Notes, Amazon orders for the UK, https://www.amazon.co.uk/dp/B012HWC8SU/ref=cm_sw_em_r_mt_dp_AYC5Q7G3H2B3T4BCHQY0 Campbell's Physiology Notes https://www.amazon.co.uk/dp/0955379725/ref=cm_sw_em_r_mt_dp_K0MXMAP26Y77TY4J90FB the disease is mild in almost all of the cases seen so far, Dr Rochelle Walensky, CDC https://www.theguardian.com/world/2021/dec/09/cdc-chief-omicron-mild-early-data-us-spread-variant 75% of US cases vaccinated Scotland, 'tsunami' of Omicron https://www.dailymail.co.uk/news/article-10295867/Omicron-infecting-4-000-BRITONS-day.html Families in Scotland, to self-isolate for 10 days if one member tests positive, regardless of their vaccination status and even if they initially get a negative PCR test UK Government working on a 'Plan C' UK, Health Security Agency https://twitter.com/UKHSA/status/1468951053903142913?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet https://www.gov.uk/government/news/covid-19-variants-identified-in-the-uk Omicron is displaying a significant growth advantage over Delta, likely to outcompete Delta in the UK and become the dominant variant. If the growth rate and doubling time continue, at least 50% of coronavirus (COVID-19) cases to be caused by Omicron variant by mid-December One million by end of December 1% = 10,000 Omicron displays a reduction in protection offered by having had a previous infection or vaccination. There is insufficient data to make any assessment of protection against severe disease, or to assess the severity of illness caused by Omicron. Further studies are underway in the UK and abroad. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1039644/Omicron_SGTF_case_update_FINAL.pdf https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings Graph refs https://ourworldindata.org/coronavirus SA. Live data, hospital patients who have tested positive https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/ South Africa references https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/sars-cov-2-genomic-surveillance-update/ Weekly deaths in SA https://www.samrc.ac.za/reports/report-weekly-deaths-south-africa Variants in SA https://www.worldometers.info/coronavirus/country/south-africa/ https://www.gov.uk/government/publications/sage-98-minutes-coronavirus-covid-19-response-7-december-2021/sage-98-minutes-coronavirus-covid-19-response-7-december-2021 Hospital admissions from Omicron should be expected to follow soon (high confidence). Though there remain some important uncertainties, Early verbal reports indicate that hospitalisations due to Omicron are now increasing in South Africa. The doubling time for new Omicron infections is currently around 3 days in England It is unlikely to be any slower than a 5-day doubling time (high confidence) Household studies show higher secondary attack rates (high confidence). Why is omicron more transmissible? Combinations of transmissibility and immune escape Some early indications from South Africa suggest less severe disease in those hospitalised A modest reduction in severity would not avert high numbers of hospitalisations if growth rates remained very high. One thousand per day be end of month The peak is highly likely to be higher than 1,000 to 2,000 Omicron hospital admissions per day without intervention For it to be below this level there would need to be only a small degree of immune escape and very high protection from boosters against Omicron With very rapid doubling times a large wave could occur leading to synchronous absences from work. With lags of the order of two or more weeks, and doubling times Learn more about your ad choices. Visit megaphone.fm/adchoices

    International omicron multiplication
  6. 7h ago

    UK, 50% omicron present

    UK, majority of London cases omicron by tomorrow, Link to free download of my 2 textbooks http://159.69.48.3/ Campbell's Pathophysiology Notes, Amazon orders for the UK, https://www.amazon.co.uk/dp/B012HWC8SU/ref=cm_sw_em_r_mt_dp_AYC5Q7G3H2B3T4BCHQY0 Campbell's Physiology Notes https://www.amazon.co.uk/dp/0955379725/ref=cm_sw_em_r_mt_dp_K0MXMAP26Y77TY4J90FB https://www.youtube.com/watch?v=L9zDnYEgX-U London https://www.youtube.com/watch?v=L9zDnYEgX-U Omicron, 40% of cases Tomorrow, 50% + of cases Boris Johnson At least one UK Omicron death I think the idea that this is somehow a milder version of the virus, I think that’s something we need to set on one side and just recognise the sheer pace at which it accelerates through the population. So the best thing we can do is all get our boosters. Mr Javid https://www.bbc.co.uk/news/live/uk-59632655 Hospitalisations due to large numbers https://www.youtube.com/watch?v=VwyeCeTfiN8 https://www.lbc.co.uk/radio/presenters/tom-swarbrick/south-africa-top-doc-angelique-coetzee-stresses-omicron-mild/ https://www.youtube.com/watch?v=7T0Qiyy854w&t=33s https://www.bbc.co.uk/news/av/uk-59450988 https://metro.co.uk/2021/12/13/south-african-doctor-who-found-omicron-variant-insists-its-mild-15761122/ South Africa https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/ https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/covid-19-special-reports/the-initial-and-daily-covid-19-effective-reproductive-number-in-south-africa/ Cyril Ramaphosa, 69, tested positive, Sunday Mild symptoms Louise I am in the Western Cape province in SA where we have just entered our fourth wave, behind other provinces like Gauteng, which seems to have just peaked. Even though our area hasn’t been hit badly by Omicron infections yet, cases are rising quite quickly. Compared to Delta, where you could feel people were very anxious about contracting that variant and almost everyone knew someone in hospital and most knew someone who had died, the mood is definitely different. We are just not hearing about mass hospitalisations like in the third wave and those that are testing positive are mainly feeling flu like symptoms for a few days and then recovering. We are really hopeful that Omicron is definitely much milder. US Cases https://covid.cdc.gov/covid-data-tracker/#trends_dailydeaths Hospitalizations https://covid.cdc.gov/covid-data-tracker/#hospitalizations Pakistan NIH able to confirm … that a recently suspected sample from Karachi is indeed the Omicron variant France Current 5th wave is delta Martin Hirsch, Paris’s AP-HP hospitals group Omicron variant, next month India Very low rates of infection Essential no social distancing Big political rallies Omicron variant, 36 cases 3% of the virus sequences Thailand 3 months to booster after 2nd dose Indonesia Start vaccinations for 6- to 11-year-olds Western Australia Fully reopen borders on 5 February Expected to hit 90% fully vaccinated target Norway https://www.theguardian.com/world/live/2021/dec/13/covid-news-live-boris-johnson-warns-of-omicron-tidal-wave-south-african-president-tests-positive Prime Minister Jonas Gahr Stoere The situation is serious. The spread of infection is too high and we have to take action to limit this development Denmark https://files.ssi.dk/covid19/omikron/statusrapport/rapport-omikronvarianten-12122021-k29d 22nd November to 12 December A total of 2,471 B.1.1.529 (Omicron) SARS-CoV-2 cases in Denmark. Omicron cases are identified through variant PCR and whole-genome sequencing Learn more about your ad choices. Visit megaphone.fm/adchoices

    UK, 50% omicron present

About

Hello Everyone, My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/ Twitter, https://twitter.com/Johnincarlisle Disclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health care provider

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