AudioScholar Critical Care Weekly

AudioScholar

Critical Care — a weekly podcast briefing of the most significant peer-reviewed critical care literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 35m ago

    This Week in Critical Care — Oct 28, 2026

    Editor's Pick: Delay From Hypotension Onset to Appropriate Antifungal Therapy Initiation Is the Critical Determinant of Outcome in Candida Septic Shock (Critical Care Medicine, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning shock and haemodynamic monitoring, the airway and liberation from mechanical ventilation, and the bedside tools and frameworks that shape everyday ICU care. This week's papers: 1. Delay From Hypotension Onset to Appropriate Antifungal Therapy Initiation Is the Critical Determinant of Outcome in Candida Septic Shock. — Critical Care Medicine 2026 2. Heterogeneous cardiovascular responses to acute mean arterial pressure augmentation in septic shock: the role of ventriculo-arterial coupling and venous return. — Critical Care 2026 3. Brachial-to-Radial Pressure Gradient in Critically Ill Patients Treated With Vasoactive Agents: A Prospective Observational Study. — Critical Care Medicine 2026 4. Comparative Analysis of Tracheal Intubation-Associated Cardiac Arrest in 2015-2023: A Report From the National Emergency Airway Registry for Children Multicent… — Critical Care Medicine 2026 5. Association of Acute Respiratory Distress Syndrome Radiographic Findings Identified by Machine Learning and Outcomes of Patients Receiving Invasive Mechanical… — Critical Care Medicine 2026 6. Toward targeted assessment of inspiratory muscle weakness before extubation: a pooled individual patient data analysis from multiple observational cohorts in c… — Critical Care 2026 7. Music Therapy During Weaning From Invasive Mechanical Ventilation in the ICU: A Randomized Controlled Trial. — Critical Care Medicine 2026 8. Furosemide Stress Test in Adults and Children With Acute Kidney Injury: A Systematic Review and Meta-Analysis. — Critical Care Medicine 2026 9. Principles of drug dosing for obese patients in the intensive care unit. — Intensive Care Medicine 2026 10. European Society of Intensive Care Medicine consensus statement on human-centred partnership in the intensive care unit. — Intensive Care Medicine 2026 Listen at https://audioscholar.cc/episode/v5bnvqe7c5

  2. Oct 21

    This Week in Critical Care — Oct 21, 2026

    Editor's Pick: Intraoperative Dobutamine Plus Norepinephrine to Prevent Postoperative Acute Kidney Injury in Septic Shock: A Randomized Clinical Trial (JAMA, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning haemodynamic management in septic shock, sedation and liberation from respiratory support, and the everyday practices of fluids, urine output and family presen… This week's papers: 1. Effect of Vasopressin Initiation Threshold on Septic Shock Mortality: The VASSPR Cluster Crossover Randomized Strategy Trial. — JAMA 2026 2. Intraoperative Dobutamine Plus Norepinephrine to Prevent Postoperative Acute Kidney Injury in Septic Shock: A Randomized Clinical Trial. — JAMA 2026 3. What every intensivist should know about dynamic left ventricular outflow tract obstruction. — Journal of Critical Care 2026 4. Guidelines for the management of atrial fibrillation in adult patients admitted to an intensive care unit. — Annals of Intensive Care 2026 5. Isoflurane-Based Inhaled Sedation in Mechanically Ventilated Adults With Acute Hypoxemic Respiratory Failure: The SAVE-ICU Randomized Clinical Trial. — JAMA 2026 6. Open Visiting Policy and Delirium in Adult Patients in ICUs: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. — Critical Care Medicine 2026 7. Weaning Strategies for High-Flow Nasal Cannula in Critically Ill Adults: A Randomized Clinical Trial. — Critical Care Medicine 2026 8. Permissive versus conventional weaning from venovenous ECMO in patients with ARDS: a retrospective cohort study. — Annals of Intensive Care 2026 9. Fluid Therapy in Mechanically Ventilated Critically Ill Adult Patients. — JAMA 2026 10. Association of Oliguria With Acute Kidney Injury, Chronic Kidney Disease, and Mortality: Determining the Optimal Threshold in Critically Ill Patients. — Critical Care Medicine 2026 Listen at https://audioscholar.cc/episode/tgvuap6veq

  3. Oct 14

    This Week in Critical Care — Oct 14, 2026

    Editor's Pick: Comparative Effectiveness of Phenobarbital vs Diazepam for Alcohol Withdrawal Syndrome (JAMA Internal Medicine, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning sepsis therapies from blood purification to antibiotic choice and dosing, prevention of respiratory complications in ventilated and postoperative patients, and… This week's papers: 1. Polymyxin B hemoadsorption in endotoxic septic shock: ten questions on the Tigris trial. — Critical Care 2026 2. The effects of hemoadsorption in patients with sepsis-associated persistent severe AKI who require CRRT: A prospective, randomized controlled pilot study. — Annals of Intensive Care 2026 3. Individualized Treatment Effects of Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized with Acute Infection. — American Journal of Respiratory and Critical Care Medicine 2026 4. Early piperacillin exposure during continuous infusion in critically ill patients: the impact of renal and liver dysfunctions. — Annals of Intensive Care 2026 5. Comparative Effectiveness of Phenobarbital vs Diazepam for Alcohol Withdrawal Syndrome. — JAMA Internal Medicine 2026 6. Effectiveness of Continuous Automatic Endotracheal Cuff Pressure Monitoring in Preventing Ventilator-Associated Pneumonia in the Pediatric Intensive Care Unit:… — Chest 2026 7. Prophylactic high-flow nasal oxygen vs. conventional oxygen for prevention of postoperative respiratory complications: a randomized trial. — Critical Care 2026 8. Mechanical versus manual bag-valve ventilation during cardiopulmonary resuscitation in adults with cardiac arrest: A systematic review and Bayesian meta-analys… — Resuscitation 2026 9. Early Post-ROSC Laboratory Phenotypes and Clinical Outcomes after Out-of-Hospital Cardiac Arrest: A 10-Year National Cohort Study. — Resuscitation 2026 10. Fibrinolytic Activation and Its Association with Mortality After Traumatic and Thermal Injury. — Shock 2026 Listen at https://audioscholar.cc/episode/8q9uwnbuud

  4. Oct 7

    This Week in Critical Care — Oct 7, 2026

    Editor's Pick: Pulse versus Nonpulse Corticosteroid Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized Clinical Trial (SAFER) (American Journal of Respiratory and Critical Care Medicine, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning blood pressure management in shock and hypertensive emergencies, rhythm and drug decisions in cardiac arrest, anti-inflammatory therapy in lung injury, and how… This week's papers: 1. Early multimodal vasopressor strategy in septic shock: results of the TRICYCLE randomized controlled trial. — Critical Care 2026 2. High blood pressure-targeted management associated with reduced benefits of higher body mass index in elderly patients with septic shock: a post hoc analysis o… — Annals of Intensive Care 2026 3. Hypertensive crisis in the critically ill. — Annals of Intensive Care 2026 4. Amiodarone After Conversion From a Non-shockable to a Shockable Rhythm in Out-of-Hospital Cardiac Arrest A Propensity Score-Matched Analysis from the German Re… — Resuscitation 2026 5. Impact of Cardiac Rhythm Dynamics during Cardiopulmonary Resuscitation on Clinical Outcomes in Patients Treated with Extracorporeal Cardiopulmonary Resuscitati… — Resuscitation 2026 6. Pulse versus Nonpulse Corticosteroid Therapy in Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Multicenter, Randomized Clinical Trial (SAFER). — American Journal of Respiratory and Critical Care Medicine 2026 7. TISA-818, an Anti-inflammatory Conjugate of Montelukast-Decapeptide, in Acute Respiratory Distress Syndrome Due to Pulmonary Infection: A Phase 2 Randomized Tr… — Chest 2026 8. Evaluating plasma ferritin and suPAR as treatable traits for critically ill patients with COVID-19 treated with anakinra: an exploratory analysis of the immune… — Critical Care 2026 9. A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study. — Critical Care 2026 10. Epidemiology of platelet transfusion in critically ill patients: a multicentre observational prospective study. — Journal of Critical Care 2026 Listen at https://audioscholar.cc/episode/79xe8dk7mk

  5. Sep 30

    This Week in Critical Care — Sep 30, 2026

    Editor's Pick: Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial (JAMA, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning haemodynamic targets and vasoactive drug exposure, the control of breathing and sedation in acute respiratory distress syndrome, and how we staff and organise… This week's papers: 1. Duration of antibiotic therapy in sepsis and severe infections in critically ill patients. — American Journal of Respiratory and Critical Care Medicine 2026 2. Permissive Blood Pressure Targets in Pediatric Critical Care: The PRESSURE Randomized Clinical Trial. — JAMA 2026 3. Tracheal intubation in ICU: Past, present, and future. — Journal of Critical Care 2026 4. Volatile anesthetic sedation in acute respiratory distress syndrome. — Intensive Care Medicine 2026 5. Optimization of Pharmacist Medication Management and Mortality in the Intensive Care Unit. — Chest 2026 6. Time-Dependent Effects of Inotropic Exposure During Venoarterial Extracorporeal Membrane Oxygenation Support on the Probability of Extracorporeal Membrane Oxyg… — Critical Care Medicine 2026 7. Effect of ondansetron on respiratory drive in patients with acute respiratory distress syndrome. — Chest 2026 8. Enhanced nighttime and continuous critical care physician coverage in adult intensive care units: A systematic review and meta-analysis. — Journal of Critical Care 2026 9. Effects of vasopressor dose on microcirculation despite preserved macrohemodynamic targets in septic shock: a prospective observational study. — Journal of Critical Care 2026 10. Association between cerebral autoregulation and optimal cerebral perfusion pressure after hypertensive intracerebral hemorrhage under neuromultimodal monitorin… — Journal of Critical Care 2026 Listen at https://audioscholar.cc/episode/zan3szqnc7

  6. Sep 22

    This Week in Critical Care — Sep 22, 2026

    Editor's Pick: Impact of pre-ICU balanced crystalloids versus saline on mortality in sepsis: a propensity score-matched multicenter cohort study (Chest, 2026) Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning fluid and kidney management in the sickest patients, cardiac arrest and ventilator liberation, and the softer but no less consequential science of how we make… This week's papers: 1. Impact of pre-ICU balanced crystalloids versus saline on mortality in sepsis: a propensity score-matched multicenter cohort study. — Chest 2026 2. Multicomponent Pulmonary Rehabilitation for Prolonged Mechanical Ventilation in Patients Aged 80 Years or Older: A Randomized Controlled Trial. — Chest 2026 3. Comparative Effectiveness of Lidocaine and Amiodarone for Refractory VF/pVT in Adult In-Hospital Cardiac Arrest: Insights from a Nationwide Multicenter Chinese… — Chest 2026 4. A multicenter randomized, double-blinded placebo-controlled phase 2 trial to evaluate safety and efficacy of ilofotase alfa in patients at risk for kidney inju… — Intensive Care Medicine 2026 5. Epidemiology of Critically Ill Patients With Cirrhosis Undergoing Continuous Renal Replacement Therapy: A Contemporaneous Parallel Analysis of the HRS-HARMONY… — Critical Care Medicine 2026 6. Alveolar Ventilation Efficiency Assessed via Capnography is Associated with Improved Outcomes in Pediatric Cardiac Arrest. — American Journal of Respiratory and Critical Care Medicine 2026 7. Lymphopenia and mortality in adult sepsis: A systematic review and focused meta-analysis of prognostic evidence. — Journal of Critical Care 2026 8. Epilepsy After Antipsychotic Prescription in Survivors of Traumatic Brain Injury: A Population-Based Cohort Study. — Critical Care Medicine 2026 9. The Role of Regret in Extracorporeal Membrane Oxygenation Candidacy Decision-Making. — Chest 2026 10. Social Media and Crisis Care Principles During Pandemics and Disasters: A Consensus Report From a Subgroup of the Task Force for Mass Critical Care. — Chest 2026 Listen at https://audioscholar.cc/episode/ncd4uqtwkh

  7. Sep 15

    This Week in Critical Care — Sep 15, 2026

    Editor's Pick: Intravenous or Intraosseous Vascular Access in Cardiac Arrest: An Individual Participant Data Meta-Analysis (Resuscitation, 2026) Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning resuscitation and mechanical circulatory support, the shifting evidence around sepsis targets and phenotype-guided therapy, and a cluster of studies on mechani… This week's papers: 1. Intravenous or Intraosseous Vascular Access in Cardiac Arrest: An Individual Participant Data Meta-Analysis. — Resuscitation 2026 2. Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort. — Intensive Care Medicine 2026 3. Phenotype-guided polymyxin B haemoadsorption in abdominal septic shock: a 2015-2026 evidence synthesis and proposed clinical pathway. — Shock 2026 4. Mortality Effect of Peripheral Perfusion-Guided Resuscitation in Vasodilatory Shock: A Systematic Review and Dual Frequentist-Bayesian Meta-Analysis of Randomi… — Critical Care Medicine 2026 5. Rehabilitation and the post-intensive care syndrome across the recovery continuum: a narrative review. — Intensive Care Medicine 2026 6. Sepsis identification and bundle delivery in US emergency departments, 2012-2022: A nationally representative analysis. — Journal of Critical Care 2026 7. Epidemiology of continuous renal replacement therapy in critically ill adults on ECMO: A multicenter cohort study. — Journal of Critical Care 2026 8. Landscape of Biomarker Use in Critically Ill Patients: Systematic Evidence Map of Acute Kidney Injury and Implications for Practice. — Critical Care Medicine 2026 9. Between-hospital variation in liberation from invasive mechanical ventilation: Consequences of ignoring death as a competing risk. — Journal of Critical Care 2026 10. In-Hospital Cardiac Arrest in Impella-Supported Cardiogenic Shock: Insights From the J-PVAD Registry. — Resuscitation 2026 Listen at https://audioscholar.cc/episode/rmgwdez2c6

  8. Sep 8

    This Week in Critical Care — Sep 8, 2026

    Editor's Pick: Ketamine for Analgosedation in Mechanically Ventilated Adults: A Double-Blind Randomized Trial (Critical Care Medicine, 2026) Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning sedation and liberation from mechanical ventilation, bedside physiology for shock and kidney injury, resuscitation rhythms and phenomena, and the shifting epid… This week's papers: 1. Ketamine for Analgosedation in Mechanically Ventilated Adults: A Double-Blind Randomized Trial. — Critical Care Medicine 2026 2. Extracorporeal CO2 elimination for acute exacerbation of severe COPD requiring invasive mechanical ventilation: a randomized controlled trial (the X-COPD trial… — Critical Care 2026 3. Serially measured diaphragmatic thickening fraction, but not diaphragmatic excursion, was associated with subsequent intubation during high-flow nasal cannula… — Journal of Critical Care 2026 4. Feasibility and Operator-Reported Utility of Transesophageal Lung Ultrasound As an Adjunct to Resuscitative Transesophageal Echocardiography in the Evaluation… — Critical Care Medicine 2026 5. Early renal perfusion phenotypes and renal recovery in critically ill patients with or at risk for acute kidney injury: a prospective multicenter cohort study. — Shock 2026 6. Early Arterial pH Changes as Strong Predictors of Mortality in Sepsis: A Multicenter Cohort Study. — Shock 2026 7. Pulseless electrical activity versus asystole as initial pulseless rhythm in children: challenging convention regarding non-shockable rhythms. — Resuscitation 2026 8. Trends in the incidence and outcomes of cardiopulmonary resuscitation-induced consciousness in out-of-hospital cardiac arrest: a retrospective study. — Resuscitation 2026 9. Predictors of Critical Illness During Different COVID-19 Pandemic Periods Compared With Seasonal Influenza. — Critical Care Medicine 2026 10. Temporal trends in critical care burden and outcomes of Andes virus-associated hantavirus cardiopulmonary syndrome: a national Chilean cohort. — Intensive Care Medicine 2026 Listen at https://audioscholar.cc/episode/chyf36qq5h

About

Critical Care — a weekly podcast briefing of the most significant peer-reviewed critical care literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.