AudioScholar Critical Care Weekly

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Critical Care — a weekly podcast briefing of the most significant peer-reviewed critical care literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 6d ago

    This Week in Critical Care — Aug 21, 2026

    Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning resuscitation decisions in septic shock, the mechanics and pharmacology of the airway, and a set of studies on diagnostics, glucose timing and system-level saf… This week's papers: 1. Early red blood cell transfusion strategy in septic shock among patients with cancer: the TRANSPORT randomized controlled trial — Intensive Care Medicine 2026 2. Impact of a strategy using multiplex PCR on targeted antibiotic therapy for patients with suspected ventilator-associated pneumonia or hospital-acquired pneumo… — Intensive Care Medicine 2026 3. Induction Agents for Tracheal Intubation of Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials — Chest 2026 4. ARDS management beyond the guidelines: a practical physiology-based approach to individualized care — Intensive Care Medicine 2026 5. Respiratory mechanics modifies the impact of ventilator settings on clinical outcome in patients with acute brain injury — Intensive Care Medicine 2026 6. Effect of early versus delayed or no insulin therapy for moderate hyperglycemia in ICU patients: A target trial emulation — Chest 2026 7. Physiological comparison of high-flow oxygen via endotracheal tube and T-piece strategies during spontaneous breathing trials: a randomized crossover study — Critical Care 2026 8. Association of timing of vasopressin initiation with renal replacement therapy in septic shock patients — Journal of Critical Care 2026 9. Incidence, Outcomes, and Risk Factors for Mortality in Patients With Sepsis in South Korea: A Nationwide Cohort Study — Critical Care Medicine 2026 10. Lessons from preventable ICU-related coronial deaths: A large-language-model-assisted national analysis of adult cases in Australia (1997 to 2025) — Journal of Critical Care 2026 Listen at https://audioscholar.cc/episode/yeg779qbaw

  2. Aug 14

    This Week in Critical Care — Aug 14, 2026

    Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning septic shock resuscitation and the timing of vasoactive support, kidney replacement therapy and fluid management, and the evolving evidence base in hypoxemic r… This week's papers: 1. Ultra-early versus early adjunctive vasopressin initiation after norepinephrine escalation in septic shock: a target trial emulation — Intensive Care Medicine 2026 2. A 1-Hour Resuscitation Bundle for Prehospital Management of Septic Shock — Critical Care Medicine 2026 3. Heterogeneous Treatment Effects of Renal Replacement Therapy in Critically Ill Patients: A Multicenter Observational Study Using a Japanese ICU Registry — Critical Care Medicine 2026 4. Efficacy and safety of pantoprazole for stress-ulcer prophylaxis in critically ill patients: A systematic review and meta-analysis of randomized controlled tri… — Journal of Critical Care 2026 5. Net Ultrafiltration Rate and Mortality in Critically Ill Patients: A Multicenter Cohort Study With Analysis of Fluid Balance Changes — Critical Care Medicine 2026 6. Risk of blood culture contamination during central venous catheter insertion in critically ill adults: a self-controlled study — Journal of Critical Care 2026 7. Epidemiology, Ventilatory Patterns, and Outcomes in Acute Hypoxemic Respiratory Failure Among ICU Patients Requiring Respiratory Support: A Registry-Based Coho… — Critical Care Medicine 2026 8. Predictive value of diaphragmatic ultrasound for weaning outcomes in mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary… — Critical Care 2026 9. Corticosteroids in ARDS: old controversies, new insights, and future directions — Intensive Care Medicine 2026 10. Interventions with a significant mortality difference in acute respiratory distress syndrome: A systematic review and comparison with Guidelines — Journal of Critical Care 2026 Listen at https://audioscholar.cc/episode/65hfc223nc

  3. Aug 5

    This Week in Critical Care — Aug 5, 2026

    Welcome to This Week in Critical Care. This week we're covering eight notable papers spanning the kidney in critical illness, the search for treatable sepsis phenotypes, and how we dose and interpret our anti-inflammatory therapies. Let's dive in. W… This week's papers: 1. Renal Resistive Index Responsiveness to a Mean Arterial Pressure Test As a Guide for Mean Arterial Pressure Target in the Early Phase of Septic Shock: A Physio… — Critical Care Medicine 2026 2. Safety and outcomes of dapagliflozin initiation in critically ill patients with acute kidney injury: A post-hoc analysis of the DEFENDER trial — Journal of Critical Care 2026 3. High-dose corticosteroids are associated with higher mortality in patients with COVID-19 ARDS: Results from a nationwide observational study — Journal of Critical Care 2026 4. Inflammatory Phenotypes In Severe Pneumonia: Clinical Evidence To Mouse Models For Precision Therapeutics — American Journal of Respiratory and Critical Care Medicine 2026 5. STARDaki: a consensus-based STARD extension for standardized reporting of diagnostic accuracy in acute kidney injury — Intensive Care Medicine 2026 6. Phenotyping Sepsis at Emergency Department Presentation Using Early Clinical Data: A Multicenter Cohort Study — Shock 2026 7. H3.1 Nucleosomes to Predict Renal Replacement Therapy and Mortality in Sepsis: A Secondary Analysis of the SISPCT Randomized Control Trial — Critical Care Medicine 2026 8. Renal impairment after burn-associated shock — Shock 2026 Listen at https://audioscholar.cc/episode/xjzuvg6qnq

  4. Jul 31

    This Week in Critical Care — Jul 31, 2026

    Welcome to This Week in Critical Care. This week we're covering 10 notable papers spanning individualized physiological monitoring, optimization of shock resuscitation, and the clinical and human complexities of advanced life support. Let's dive in.… This week's papers: 1. A decade of SEP-1 compliance and sepsis mortality in the United States. — Critical care (London, England) 2026 2. Intracranial pressure physiology, monitoring and individualized management in the acute brain injured patient. — Intensive care medicine 2026 3. Assessing tissue perfusion during septic shock resuscitation through the vascular waterfall lens. — American journal of respiratory and critical care medicine 2026 4. Re-evaluation of oxygenation and oxygen exposure in patients with ARDS and veno-venous extracorporeal membrane oxygenation. — Critical care (London, England) 2026 5. Examining the intersection of biologic sex and predicted body weight in patients with acute respiratory distress syndrome. — Critical care (London, England) 2026 6. Terminal complement inhibition is associated with renal, hematologic, and thrombotic complications during septic shock: A global propensity score-matched cohor… — Journal of critical care 2026 7. The Human Impact of ECMO: Best Practices to Improve Experiences of Patients, Families, and Clinicians. — Chest 2026 8. SDD as a stewardship intervention: the missing feedback loop. — Intensive care medicine 2026 9. Bradycardia associated with dexmedetomidine in critically ill patients: A retrospective study of risk factors and clinical outcomes. — Journal of critical care 2026 10. Anabolic androgen therapy in critically ill adults: A systematic review and meta-analysis. — Journal of critical care 2026 Listen at https://audioscholar.cc/episode/yjfgnnewhb

  5. Jul 22

    This Week in Critical Care — Jul 22, 2026

    Welcome to This Week in Critical Care. This week we're covering 5 notable papers spanning metabolic resuscitation, extracorporeal support, mechanical ventilation weaning, and health equity in intensive care. Let's dive in. We begin with metabolic re… This week's papers: 1. Sodium bicarbonate therapy in severe metabolic acidemia: an individual patient data meta-analysis of the BICAR-ICU and BICAR-ICU2 trials. — Critical care (London, England) 2026 2. Hemoperfusion during extracorporeal membrane oxygenation: an updated systematic review and meta-analysis of 8,151 patients. — Critical care (London, England) 2026 3. Prone positioning in ARDS. — Intensive care medicine 2026 4. Health-Economic Value of Transvenous Diaphragm Neurostimulation in Ventilator Weaning. — Critical care medicine 2026 5. Socioeconomic Disparities and the Role of Comorbidity in Hospital Mortality: A Dutch Nationwide Critical Care Cohort Study. — Critical care medicine 2026 Listen at https://audioscholar.cc/episode/wkqtsk3w88

  6. Jul 15

    This Week in Critical Care — Jul 15, 2026

    Welcome to This Week in Critical Care. This week we're covering 9 notable papers spanning cardiopulmonary resuscitation dynamics, advanced respiratory support and nutrition strategies, and challenging clinical decisions in specialized intensive care… This week's papers: 1. Nutrition and Exercise in Critical Illness (NEXIS) trial: randomized trial of combined in-bed cycling and intravenous amino acid plus usual care. — American journal of respiratory and critical care medicine 2026 2. Acute exacerbation in fibrotic interstitial lung disease: An International Working Group Report. — American journal of respiratory and critical care medicine 2026 3. High-flow nasal cannula oxygen during breaks from noninvasive ventilation after extubation: an observational study. — Intensive care medicine 2026 4. Ventilation parameters during Advanced Life Support in cardiac arrest (CAvent): A multicentre observational cohort study. — Resuscitation 2026 5. Discordant Neuron-Specific Enolase and Neurologic Outcomes in Out-of-Hospital Cardiac Arrest: A Decade-Long Analysis. — Resuscitation 2026 6. Incretins Predict Response to Enteral Nutrition Strategies in the EDEN Trial: A Secondary Analysis. — American journal of respiratory and critical care medicine 2026 7. Anticoagulation initiation during ECMO in trauma patients with traumatic intracranial hemorrhage: A narrative review and conceptual time-dependent risk framewo… — Journal of critical care 2026 8. Characterizing Infections in Children after Out-of-Hospital Cardiac Arrest. — Resuscitation 2026 9. Perceived Cognitive Load Among Emergency Department Code Blue Teams: Distribution, Correlates and Relationship with Team Performance. — Resuscitation 2026 Listen at https://audioscholar.cc/episode/dys5yyqjbf

  7. Jul 7

    This Week in Critical Care — Jul 7, 2026

    Welcome to This Week in Critical Care. This week we're covering 9 notable papers spanning sepsis management and cardiovascular resuscitation, advanced airway and arrest care, and optimization of daily intensive care unit practices including respirato… This week's papers: 1. Mortality effect of albumin fluid resuscitation in adults with septic shock: a systematic review and dual frequentist-bayesian meta-analysis of randomised tria… — Critical Care 2026 2. In mechanically ventilated ICU patients, low vs. high physical restraint use did not differ for days free of delirium or coma at 14 d. — Annals of Internal Medicine 2026 3. In acute hypoxemic respiratory failure, high-flow vs. standard oxygen therapy did not reduce mortality at 28 d. — Annals of Internal Medicine 2026 4. Efficacy of higher-dose versus lower-dose corticosteroids in community-acquired pneumonia: a systematic review and network meta-analysis. — Critical Care 2026 5. Prevention of arterial catheter-related bloodstream infections: current evidence and future directions. — Critical Care 2026 6. Volume-controlled mechanical ventilation during cardiopulmonary resuscitation: A systematic review and meta-analysis. — Resuscitation 2026 7. Physiological and clinical effects of selected airway clearance techniques in mechanically ventilated adult ICU patients: a systematic review and synthesis wit… — Critical Care 2026 8. Sedation Early After Return of Spontaneous Circulation and During Pre-Hospital Transport After Out-Of-Hospital Cardiac Arrest: Retrospective Analysis of the Af… — Resuscitation 2026 9. Coronary microvascular function in patients with sepsis and myocardial injury: an invasive coronary physiology study. — Critical Care 2026 Listen at https://audioscholar.cc/episode/qxfcbku4cd

  8. Jun 30

    This Week in Critical Care — Jun 30, 2026

    Welcome to This Week in Critical Care. This week we are covering eight notable papers spanning advanced life support strategies, precision medicine in sepsis and infectious diseases, and perioperative organ protection. Let's dive in. We begin with m… This week's papers: 1. Noninvasive Respiratory Support for Adult Patients with Acute Respiratory Failure. An Official American Thoracic Society Clinical Practice Guideline. — American journal of respiratory and critical care medicine 2026 2. HIgh versus STAndard blood Pressure target in hypertensive high-risk patients undergoing elective major abdominal surgery: the HISTAP multicenter randomized cl… — Intensive care medicine 2026 3. Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic sh… — Intensive care medicine 2026 4. Interpreting protein dose trials in critical illness: a guide for the bedside clinician. — Critical care (London, England) 2026 5. ECMO for patients with obesity: evidence and practice. — Intensive care medicine 2026 6. Burden of and risk factors for neurological complications in critical illness. — Intensive care medicine 2026 7. Decoding candidemia in critically ill patients: unsupervised clustering identifies three unique phenotypes. — Critical care (London, England) 2026 8. Association between red blood cell transfusion volume and infection risk: a dose-response analysis of a nationwide trauma registry. — Critical care (London, England) 2026 Listen at https://audioscholar.cc/episode/hxftrqak62

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Critical Care — a weekly podcast briefing of the most significant peer-reviewed critical care literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

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