Can't Help But Laugh with Frank & Greg Galifianakis

Greg Galifianakis

Season 1: Greg Gets Man Cancer Welcome to the funniest show about the one thing men hate talking about. The Galifianakis cousins are teaming up to break down medical taboos and tackle prostate cancer awareness with a healthy dose of humor. This channel is dedicated to saving lives through early testing, blending vital health facts with a lighthearted approach that proves taking care of your body doesn't have to be intimidating. From demystifying the PSA test to sharing practical advice for men approaching 40 and beyond, we are making men's health conversations accessible, urgent, and entertaining. If you want the real facts on cancer prevention without the stiff medical jargon, hit Subscribe and join us in normalizing the conversation.

Episodes

  1. 6d ago ·  Video

    Can't Help But Laugh: INTRO

    Hi My name is Greg Galifianakis. That's my cousin Frank. You probably know my famous Uncle, Nick Galifianakis, US Congressman from North Carolina's 4th District. This isn't about him. This is about my prostate. But let's back up a sec and see how we got here. I grew up in Wilkesboro, North Carolina, home of Nascar, Moonshine, Merlefest and my parents Harry and Mary Francis. My Dad was the son of Greek immigrants and my mother's Scotch Irish family had been living in the shadow of the blue ridge mountains for generations. Rumor has it, the day I was born my cousin Frank was there, ready to catch me when I got pooted out of my Mom. He's always been like a big brother to me, and we've been inseparable ever since. Early in my life, I was known as "The Beast". I had red hair the color of a radio flyer wagon and so many freckles my face looked rusted. My Uncle Pete would often tell me that I wasn't really Greek and that Mom had slept with the milk man, Tyler Timmons of Flavor Rich Dairy. Even though I never got above a C average in high school, I did manage to attend my Dad's alma mater, North Carolina State University. It only took me 10 years to graduate with a degree in Sociology, which I put to immediate good use by taking a job as a mobile home salesperson- selling single wides and double wides. I had all types of jobs. Even ended up managing an online flower company, which I hated, but that's how I met my amazing wife, Gia. Along the way, we made some amazing memories, and I ate an amazing amount of food, topping out at 350 pounds. After a serious heart scare that converted me to veganism almost overnight, I started focusing on my health and lost over 130 pounds. For the first time, I felt like I was settling into my true self. Then one day at 54, while minding my own business, I was diagnosed with Prostate Cancer. I was not ready for that surprise.  Cancer has a way of changing you. And it certainly changed me. I thought I was living before my diagnosis, but I soon learned I wasn't living at all. I also learned that most men don't really talk about prostate cancer. Even if most of us will get it in our lifetime. And believe me I know why they don't. But I also know why they should. And lucky for y'all, I'm an open book. So come along as I recount my journey with my cousin Frank, warts and all. I hope if you're feeling alone, you'll fell less alone. If you have a loved one that's going through this, I hope our conversation will give you a little glimpse into their experience. And I hope no matter what your reason for listening is, we manage to make you laugh. Because sometimes it's all you can do.

    3 min

  2. 6d ago ·  Bonus Video

    Can't Help But Laugh Theme Song

    Dance to it, cry to it, mkae up some moves.... get the mood started with our theme song.

    1 min

  3. 6d ago ·  Video

    Episode 5: Family Love & Life After Cancer

    Greg Galifianakis and cousin Frank Galifianakis get reflective and practice kegels together. The origin story of "The Beast," early milestone embarrassments, and the moments that shaped everything. Greg gets real about intimacy and daily life after cancer, un-tabooing it all. Endings, beginnings, and a whole lot of laughter.

    30 min

  4. 6d ago ·  Video

    Episode 4 Florida SunBurn on the Inside

    Jacksonville confirmed it — and yep, it's exactly where they thought. On the rectum of Greg Galifianakis. So now what? Radiation and the joyous comfort of medical marijuana. Oh, and the bloodwork anxiety that nobody warns you about.

    1h 24m

  5. 6d ago ·  Video

    Episode 3 Penis Pootin'

    Catheters to penis poots, the healing journey continues at Mt Tremper in the snow. Oh the beauty and pleasure of depends adult diapers! Oh crap it's back, Greg Galifianakis' cancer returns and meeting My Man Mahmood.

    1h 24m

  6. 6d ago ·  Video

    Episode 2. Laughter Contracts

    Love, laughter, positive energy and the tools that actually get you through it. Greg Galifianakis walks us through surgery at Sloane Kettering, recovery at Mt. Tremper, and why humor isn't just a coping mechanism — it's a survival strategy.

    1h 32m

  7. 6d ago ·  Video

    Episode 1. Eatin' Alive

    Greg Galifinakis begins our story, taking cousin Frank Galifiankis on his health journey from obesity to wellness — and then the rug pull. A cancer diagnosis, rising PSA numbers, Gleason scores, and the hardest conversations with family. Where every healing journey begins.

    1h 19m
  • 7 Episodes

About

Season 1: Greg Gets Man Cancer Welcome to the funniest show about the one thing men hate talking about. The Galifianakis cousins are teaming up to break down medical taboos and tackle prostate cancer awareness with a healthy dose of humor. This channel is dedicated to saving lives through early testing, blending vital health facts with a lighthearted approach that proves taking care of your body doesn't have to be intimidating. From demystifying the PSA test to sharing practical advice for men approaching 40 and beyond, we are making men's health conversations accessible, urgent, and entertaining. If you want the real facts on cancer prevention without the stiff medical jargon, hit Subscribe and join us in normalizing the conversation.

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