AudioScholar Gastroenterology Weekly

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Gastroenterology — a weekly podcast briefing of the most significant peer-reviewed gastroenterology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 5d ago

    This Week in Gastroenterology — Oct 27, 2026

    Editor's Pick: Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial) (BMJ, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning autoimmune and cholestatic liver disease, the evolving landscape of liver injury and portal hypertension, inflammatory bowel disease from prevention to biol… This week's papers: 1. AGA/AASLD Clinical Practice Guideline on Management of Primary Biliary Cholangitis. — Gastroenterology 2026 2. A phase 2b/3 trial of saroglitazar in primary biliary cholangitis. — Hepatology 2026 3. Prevalence and outcomes of acute presentations of autoimmune hepatitis: Systematic Review and Meta-Analysis. — Clinical Gastroenterology and Hepatology 2026 4. Trends in the etiologies and outcomes of idiosyncratic drug-induced liver injury in the united states: The DILIN prospective registry, 2004 to 2024. — Hepatology 2026 5. Baveno VI criteria validation and development of a new non-invasive strategy for varices rule-out in patients with HCC (SAPHE-R: Stiffness, ALBI, Platelets, HE… — Hepatology 2026 6. Intravenous Versus Subcutaneous Induction with Guselkumab: Week 12 and Week 96 Efficacy in GALAXI 2 & 3 and GRAVITI. — Clinical Gastroenterology and Hepatology 2026 7. TASTY AND HEALTHY DIET REDUCES FECAL CALPROTECTIN IN HIGH-RISK FIRST-DEGREE RELATIVES OF PATIENTS WITH CROHN'S DISEASE: PIONIR RANDOMIZED CROSSOVER TRIAL. — Gastroenterology 2026 8. Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial). — BMJ 2026 9. Helicobacter pylori Infection - Advances, Challenges, and the Road Ahead. — New England Journal of Medicine 2026 10. 14-day versus 28-day trifluridine-tipiracil plus bevacizumab for refractory metastatic colorectal cancer (PRABITAS): a pragmatic, multicentre, open-label, rand… — The Lancet 2026 Listen at https://audioscholar.cc/episode/36gaqe6yqc

  2. Oct 21

    This Week in Gastroenterology — Oct 20, 2026

    Editor's Pick: Updated treatment targets in inflammatory bowel disease (STRIDE-III): an initiative of the International Organization for the Study of IBD (The Lancet Gastroenterology & Hepatology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning updated targets and new oral therapy in inflammatory bowel disease, treatment and its harms across liver disease and portal hypertension, and the value and… This week's papers: 1. Updated treatment targets in inflammatory bowel disease (STRIDE-III): an initiative of the International Organization for the Study of IBD. — The Lancet Gastroenterology & Hepatology 2026 2. Phase 2 Trial of Icotrokinra for Patients with Ulcerative Colitis. — New England Journal of Medicine 2026 3. Incidence and Risk Factors for C. difficile Reinfection After Faecal Microbiota Transplantation or Antibiotic Therapy. — Alimentary Pharmacology and Therapeutics 2026 4. Thyroid hormone receptor-β agonist simedeutirom (HSK31679) for Chinese patients with metabolic dysfunction-associated steatohepatitis: a 52-week, multicentre,… — The Lancet Gastroenterology & Hepatology 2026 5. Corticosteroid Exposure in Autoimmune Hepatitis: Early Toxicity, Cumulative Burden and Associations With Long-Term Patient-Reported Outcomes. — Alimentary Pharmacology and Therapeutics 2026 6. Bicentric comparison of 3-year clinical outcomes between endoscopic ultrasound-guided embolization with coil and hemostatic adjunct versus balloon-occluded ret… — Gastrointestinal Endoscopy 2026 7. Optimal Incidence Threshold for Cost-Effective Hepatocellular Carcinoma Surveillance in Alcohol-Associated Cirrhosis. — Clinical Gastroenterology and Hepatology 2026 8. Cost-Effectiveness of HCV Screening in Emergency Departments Using DETECT Hep C Trial Results. — JAMA Internal Medicine 2026 9. Implementation of Programmatic Mailed Fecal Immunochemical Testing for Colorectal Cancer Screening in the Veterans Health Administration. — American Journal of Gastroenterology 2026 10. Integrating Non-Invasive Liver Assessment into Screening Colonoscopy: A Prospective Cross-Sectional Study. — American Journal of Gastroenterology 2026 Listen at https://audioscholar.cc/episode/d5x26wxnu5

  3. Oct 14

    This Week in Gastroenterology — Oct 13, 2026

    Editor's Pick: Duodenal involvement in MUTYH-associated polyposis: findings from an international study and implications for endoscopic surveillance (American Journal of Gastroenterology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning eosinophilic esophagitis and reflux evaluation, the tailoring of immune-directed therapy in Crohn's disease and autoimmune pancreatitis, and cancer risk str… This week's papers: 1. Dupilumab Improves Esophageal Distensibility in EoE: 24-Week Results From the REMODEL Randomized Trial. — American Journal of Gastroenterology 2026 2. Diffuse esophageal eosinophilia is associated with increased endoscopic severity and topical steroid non-response in patients with eosinophilic esophagitis. — Clinical Gastroenterology and Hepatology 2026 3. Modern Approach to Reflux Testing: When, Which, and How? — American Journal of Gastroenterology 2026 4. Differential long-term efficacy of biologic and small-molecule therapies by disease location in moderate-to-severe luminal Crohn's disease: a systematic review… — Inflammatory Bowel Diseases 2026 5. Clinical management of relapse in type 1 autoimmune pancreatitis: a systematic review and meta-analysis. — American Journal of Gastroenterology 2026 6. Duodenal involvement in MUTYH-associated polyposis: findings from an international study and implications for endoscopic surveillance. — American Journal of Gastroenterology 2026 7. Population-Based Cohort Study: Colorectal Cancer Risk Stratification in Symptomatic Patients Using the Faecal Immunochemical Test, Blood Results and Patient Ch… — Alimentary Pharmacology and Therapeutics 2026 8. AASLD EXPO: Liver biopsy. — Hepatology 2026 9. Alcohol-associated liver disease. — Clinical Gastroenterology and Hepatology 2026 10. Role of remimazolam in gastrointestinal endoscopy: American Society for Gastrointestinal Endoscopy clinical practice update. — Gastrointestinal Endoscopy 2026 Listen at https://audioscholar.cc/episode/62qpsxa4sv

  4. Oct 7

    This Week in Gastroenterology — Oct 6, 2026

    Editor's Pick: 8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority, randomised controlled trial in India (The Lancet, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning cirrhosis, transplantation and viral hepatitis, the evolving picture of steatotic liver disease, ulcerative colitis therapeutics, and a cluster of luminal a… This week's papers: 1. ACG Clinical Guideline: Preventive Care for Patients With Cirrhosis. — American Journal of Gastroenterology 2026 2. Survival outcomes after liver transplantation in acute-on-chronic liver failure: A prospective study. — Journal of Hepatology 2026 3. 8 weeks versus 12 weeks of sofosbuvir-velpatasvir for treatment-naive, non-cirrhotic, chronic hepatitis C (RESOLVE): a multicentre, open-label, non-inferiority… — The Lancet 2026 4. Histologic Features and Clinical Outcomes of Lean Metabolic Dysfunction-Associated Steatotic Liver Disease. — JAMA 2026 5. Effects of MASH risk genotypes on resmetirom efficacy in patients with MASH and fibrosis. — Journal of Hepatology 2026 6. EFFICACY AND SAFETY OF ADVANCED THERAPIES AS INDUCTION THERAPY FOR ULCERATIVE COLITIS: AN UPDATED SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. — Clinical Gastroenterology and Hepatology 2026 7. Janus Kinase Inhibitors for Acute Severe Ulcerative Colitis: Comparing Upadacitinib to Tofacitinib and Rescue to Sequential Salvage therapy. — Clinical Gastroenterology and Hepatology 2026 8. Clinical Trial: Dupilumab Improves Eosinophilic Oesophagitis Outcomes Versus Placebo Regardless of Comorbidities or Treatment History in a Randomised Clinical… — Alimentary Pharmacology and Therapeutics 2026 9. Serrated Polyposis Syndrome: A Review and Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer. — American Journal of Gastroenterology 2026 10. Comparative Effectiveness of Biofeedback vs Dextranomer-Hyaluronate Injection for Fecal Incontinence: A Randomized Clinical Trial. — Clinical Gastroenterology and Hepatology 2026 Listen at https://audioscholar.cc/episode/57ja5zg2w3

  5. Sep 30

    This Week in Gastroenterology — Sep 29, 2026

    Editor's Pick: EASL-EASD-EASO Guidance for the Use of Resmetirom and Semaglutide as MASH-Targeted Therapy (Journal of Hepatology, 2026) This AudioScholar briefing is generated by artificial intelligence for healthcare professionals and trainees. It is not medical advice. Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning liver disease — from the first joint European guidance on drug therapy for steatohepatitis to a head-to-head trial of a blood test against ultrasound for li… This week's papers: 1. EASL-EASD-EASO Guidance for the Use of Resmetirom and Semaglutide as MASH-Targeted Therapy. — Journal of Hepatology 2026 2. Upadacitinib Is Associated with the Lowest Risk of Treatment Failure Among Advanced Therapies for Ulcerative Colitis: A Real-World Administrative Claims Study. — Clinical Gastroenterology and Hepatology 2026 3. Multi-target blood test for hepatocellular carcinoma early detection: a cross-sectional analysis of the prospective ALTUS study. — Journal of Hepatology 2026 4. Review Article: Cancer Surveillance for Early Detection of Liver Cancer in Patients with HBV Infection. — Alimentary Pharmacology and Therapeutics 2026 5. Characterizing the Benefits of Serial Ascitic Fluid Testing in Ambulatory Patients with Cirrhosis: A National Cohort Study. — Clinical Gastroenterology and Hepatology 2026 6. Pain management in chronic pancreatitis: beyond opioids. — The Lancet Gastroenterology & Hepatology 2026 7. Overall and Line-Specific Impact of Targeted Therapies in Advanced Biliary Tract Cancer After Chemoimmunotherapy Failure. — Journal of Hepatology 2026 8. Biologics, small molecules, and extraintestinal malignancies in inflammatory bowel disease: practical questions and evidence-based answers. — Inflammatory Bowel Diseases 2026 9. EUropean consensus on the Resolution Of SympToms After oesophago-gastric Resection (EUROSTAR): Peri-Operative Quality Initiative (POQI) consensus statement. — Gut 2026 10. Gastric and Duodenal Cancer in Lynch Syndrome: Incidence and Endoscopic Surveillance-Systematic Review and Meta-analysis. — Clinical Gastroenterology and Hepatology 2026 Listen at https://audioscholar.cc/episode/cqe7tgqdag

  6. Sep 23

    This Week in Gastroenterology — Sep 22, 2026

    Editor's Pick: Janus Kinase Inhibitors for Acute Severe Ulcerative Colitis: Comparing Upadacitinib to Tofacitinib and Rescue to Sequential Salvage therapy (Clinical Gastroenterology and Hepatology, 2026) Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning liver disease burden and risk stratification, inflammatory bowel disease therapeutics, and the endoscopic management of oesophageal and hereditary neoplasia… This week's papers: 1. Prevalence of liver fibrosis and steatotic liver disease in community-dwelling adults in China (the CHESS-LiverHealth project): cross-sectional baseline data f… — The Lancet Gastroenterology & Hepatology 2026 2. Steatotic Liver Disease Risk Scores to Predict Cirrhosis and Hepatocellular Carcinoma. — JAMA Internal Medicine 2026 3. High rates of transition to immune active disease in a cohort of strictly defined immune tolerant patients with chronic hepatitis B: results from the RADICAL c… — Gut 2026 4. Development and clinical evaluation of the modified Hepatic Encephalopathy Staging Tool. — Clinical Gastroenterology and Hepatology 2026 5. Janus Kinase Inhibitors for Acute Severe Ulcerative Colitis: Comparing Upadacitinib to Tofacitinib and Rescue to Sequential Salvage therapy. — Clinical Gastroenterology and Hepatology 2026 6. Vedolizumab trough concentrations and clinical and endoscopic outcomes in inflammatory bowel disease: a systematic review and meta-analysis. — Clinical Gastroenterology and Hepatology 2026 7. Prior endoscopic surveillance and diagnosis of Barrett-related dysplasia and cancer: evidence from a nationwide Dutch cohort. — Gut 2026 8. Long-term Outcomes After Endoscopic Resection for pMM/SM1 Esophageal Cancer: A Multicenter Prospective Cohort Study. — American Journal of Gastroenterology 2026 9. Impact of gastric length of myotomy during POEM on the incidence of gastroesophageal reflux: A randomized controlled trial. — Gastrointestinal Endoscopy 2026 10. Life expectancy and changing causes of mortality in familial adenomatous polyposis (FAP). — American Journal of Gastroenterology 2026 Listen at https://audioscholar.cc/episode/gn4rvv2ggt

  7. Sep 16

    This Week in Gastroenterology — Sep 15, 2026

    Editor's Pick: Long-term outcomes of top-down therapy versus a conventional step-up strategy in adults newly diagnosed with Crohn's disease: 5-year follow-up of the PROFILE trial (The Lancet Gastroenterology & Hepatology, 2026) Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning early aggressive therapy and imaging in Crohn's disease, the fast-moving field of fatty liver diagnosis and drug treatment, and a cluster of endoscopy paper… This week's papers: 1. Long-term outcomes of top-down therapy versus a conventional step-up strategy in adults newly diagnosed with Crohn's disease: 5-year follow-up of the PROFILE t… — The Lancet Gastroenterology & Hepatology 2026 2. Real-World Effectiveness and Safety of Upadacitinib in Patients With Crohn's Disease-A Multicentre Prospective Study From the Italian Group for the Study of In… — Alimentary Pharmacology and Therapeutics 2026 3. Baseline Magnetic Resonance Enterography Stratifies Persistence Risk of Crohn's Disease Strictures. — Clinical Gastroenterology and Hepatology 2026 4. International expert panel review for the use of resmetirom and semaglutide in the management of MASH-related fibrosis: clinical practice update. — Gut 2026 5. Assessing Strategies to Mitigate the Effect of Age When Using FIB-4 Index to Screen for MASLD-Related Liver Fibrosis. — Clinical Gastroenterology and Hepatology 2026 6. A PROSPECTIVE CLINICAL TRIAL OF EUS-SHEAR WAVE MEASUREMENT OF LIVER AND SPLEEN FOR HEPATIC FIBROSIS. — Gastrointestinal Endoscopy 2026 7. Patient-level predictors of safety and recurrence after cold versus hot snare resection of large, non-pedunculated colorectal polyps: an individual patient dat… — Gut 2026 8. Endoscopist Adherence to Post-polypectomy Surveillance Interval Recommendations Following Removal of 1-4 Non-advanced Adenomas. — Clinical Gastroenterology and Hepatology 2026 9. AGA Clinical Practice Update on Management of Ampullary Neoplasms: Expert Review. — Clinical Gastroenterology and Hepatology 2026 10. Risk of Coeliac Disease After Immune Checkpoint Inhibitor Exposure in Patients With Cancer. — Alimentary Pharmacology and Therapeutics 2026 Listen at https://audioscholar.cc/episode/drwur485kq

  8. Sep 9

    This Week in Gastroenterology — Sep 8, 2026

    Editor's Pick: Longitudinal Data from a Large, Multi-Target Stool DNA Colorectal Cancer Screening Program (American Journal of Gastroenterology, 2026) Welcome to This Week in Gastroenterology. This week we're covering 10 notable papers spanning colorectal cancer risk stratification and screening, the maturing science of non-invasive liver assessment, hepatobiliary and cancer risk in inflammatory bo… This week's papers: 1. Impact of Baseline Synchronous Adenoma Burden on the Risk of Metachronous Advanced Neoplasia. — American Journal of Gastroenterology 2026 2. Germline multigene panel testing for colorectal cancer: a systematic review and meta-analysis. — The Lancet Gastroenterology & Hepatology 2026 3. Longitudinal Data from a Large, Multi-Target Stool DNA Colorectal Cancer Screening Program. — American Journal of Gastroenterology 2026 4. Impact of Family History on Colorectal Cancer Risk in Inflammatory Bowel Disease and in Matched General Population Comparators. — Gastroenterology 2026 5. Radiological primary sclerosing cholangitis in incident inflammatory bowel disease- a prospective Copenhagen IBD Inception Cohort study. — Clinical Gastroenterology and Hepatology 2026 6. Clinical utility of a 30% reduction in VCTE-derived liver stiffness measurement for identifying histologic improvement in MASH. — Hepatology 2026 7. Personalised prediction of the individual risk of liver-related events in MASLD using the dynamics of non-invasive tests. — Clinical Gastroenterology and Hepatology 2026 8. Excessive supragastric belching can be identified in up to one-fifth of patients with conclusive gastro-oesophageal reflux disease. — Gut 2026 9. Multinational prevalence and burden of paediatric disorders of gut-brain interaction: results of the Rome Foundation paediatric global study. — Gut 2026 10. STARS Phase 3 Trial: Once-Weekly Apraglutide Reduces Parenteral Support in Short Bowel Syndrome-Intestinal Failure. — Clinical Gastroenterology and Hepatology 2026 Listen at https://audioscholar.cc/episode/dm6n53pncc

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Gastroenterology — a weekly podcast briefing of the most significant peer-reviewed gastroenterology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

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