Our Changing World

Dr Claire Concannon follows scientists into the bush, over rivers, back to their labs and many places in-between to cover the most fascinating research being done in Aotearoa New Zealand.

  1. Oct 12

    Are GLP1 drugs worth the hype?

    GLP1 - RA weight loss drugs get the Our Changing World treatment! What are they? How do they work? And what does the science say about the benefits, and the risks? Plus, beyond health outcomes, how might things change as they become more widely available? Sign up to the Our Changing World monthly newsletter here for episode backstories, science analysis and more. LEARN MORE: If you’d like a deeper understanding of how drugs such as Ozempic and Wegovy affect appetite and blood sugar regulation, Emile Donovan spoke to Dr Sebastian Furness about this on Nights.Obesity genetics researcher Giles Yeo joined Afternoons to explain why body weight is influenced by much more than willpower, and why biology plays such a powerful role in hunger and weight regulation.The study that Dr Andrew Reynolds contributed to on how obesity trends are changing around the world was published in Nature. You can read the paper here.Curious about how the major incretin drugs compare? This systematic review and meta-analysis examines the effectiveness of semaglutide, liraglutide, dulaglutide and tirzepatide for blood sugar control and other outcomes.GUESTS: Dr Andrew Reynolds, Department of Medicine, University of OtagoIN THIS EPISODE: (00:00) Introduction (01:12) How GLP-1 receptor agonists were developed as treatments for type 2 diabetes (03:55) The biology of incretins, insulin, glucagon and how these drugs work (07:20) The drugs available and funded in New Zealand (11:34) Weight loss benefits, side effects and questions about long-term use (20:30) Retatrutide, future incretin therapies and the emerging “Ozempic economy” Go to this episode on rnz.co.nz for more details

  2. Sep 21

    Searching sand dunes for lizards

    Over 80% of our coastal dune ecosystems have been lost. So, what about the native species living with them? Ayana Piper-Healion steps into Bream Bay’s sand dunes with a monitoring team to see what lizards can tell us about the health of the sand dunes. Sign up to the Our Changing World monthly newsletter for episode backstories, science analysis and more. Learn more: To find out more on what the local critics think about the Bream Bay Sand Extraction Project’s fast-track application, RNZ’s Peter de Graaf reported on a protest there earlier this year. Further north, Saturday Morning reported on significant damage being caused to dunes by thrill seekers driving vehicles through them.  Another region dealing with threatened dunes is Waimarama, where weeds are spreading from people fly-dumping garden waste. In the Hawke’s Bay, the ‘Skink Squad’ are on a mission to save the northern spotted skinks in preparation for an infrastructure project. In 2021, Our Changing World did a deep dive into dune plants and the largest supplier of plants for dune revegetation programs. Guests: Steve Johnson, Patuharakeke Te Pou Taiao Ari Carrington, resource co-ordinator at Patuharakeke Te Pou Taiao Katrina Hansen, biodiversity specialist Northland Regional Council Laura Shaft, biodiversity manager Northland Regional Council Brooke Gray, biodiversity advisor Northland Regional Council Richard Griffiths, coastal scientist Northland Regional Council Go to this episode on rnz.co.nz for more details

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Dr Claire Concannon follows scientists into the bush, over rivers, back to their labs and many places in-between to cover the most fascinating research being done in Aotearoa New Zealand.

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