Last Humans in the Loop

Chris Slowe, Marty Weiner, Zach Weinersmith

A weekly conversation about AI, technology, startups, and the future from people who've actually built the systems everyone uses. Chris Slowe CTO'd Reddit through hypergrowth and its IPO. Marty Weiner was a founding engineer at Pinterest and Reddit's first CTO. Zach Weinersmith is the creator of Saturday Morning Breakfast Cereal and the NYTimes bestselling author of books exploring the future of science and technology. Each week we debate the biggest stories, explain the technology behind them, and occasionally wander into philosophy, history, and whatever weird rabbit hole AI sends us down.

  1. 3d ago

    Would You Give AI Your Passwords?

    FRONTIER 01:26 Google unveils Gemini Argon 02:50 OpenAI releases GPT Saul 6.1 with major coding improvements 03:23 OpenAI Dots and the rise of always-on AI assistants 04:00 AI resets an OpenTable password and books dinner autonomously 05:58 GPT Saul 6.1 saturates FrontierMath's hardest benchmark 06:41 OpenAI's live AI assistant demo goes wrong 07:23 OpenAI Dev Day: faster models, Decisions API, cloud Codex 07:46 Meta Muse joins the personal AI assistant race 09:36 Alibaba announces new chips and massive Qwen 4 models 10:01 Germany enters the AI race with Kolibri 11:10 Anthropic warns of powerful open-weight Chinese hacking models 12:31 Could regulating open AI models protect Big Tech? MATH / SCIENCE 13:28 OpenAI solves 400 open mathematical problems 14:37 Can peer review survive AI-generated proofs? 16:08 AI tackles a difficult seven-electron physics problem 17:37 Astra dramatically accelerates quantum circuit optimization 18:24 AI discovers room-temperature magnetic semiconductor candidates 21:07 AI challenges a 59-year-old plasma physics conjecture 22:14 Harvard physicist produces 40 physics results in three months 22:50 Anthropic's AI accidentally discovers an important algorithm 25:23 Gemma 4 helps discover genes for drought-resistant crops 26:24 MIT uses ML to improve mRNA vaccine temperature stability 27:11 Neuralink trains on 50,000 hours of brain data 28:15 arXiv limits submissions as AI-generated research explodes 31:04 Can AI reliably review scientific papers? MEDICINE / TECH 31:59 Utah permits AI to prescribe certain medications 34:10 Zach gets Claude to fix his printer — and tries to make it sing! ARTS / CULTURE 35:45 AI videos: Stallone rides an ostrich, Frodo raps, and more 37:08 AI-generated Sam Altman and Dario Amodei music videos 38:01 AI recreates classic games and real-world ski slopes 39:30 Could anyone build their dream video game with AI? 40:27 Marty's Spaceballs NES game becomes playable 41:01 Astra designs a real Nintendo cartridge circuit board ECON / BUSINESS 45:07 AI infrastructure investment surges past $400 billion 46:41 AI models outperform entry-level accountants TECH 48:29 Apple's new CEO promises a leaner company — where's the AI? 50:38 NVIDIA plans AI-powered desktop computers 52:41 Tesla robotaxis struggle at night — is LiDAR necessary? POLITICS 53:52 Trump administration wants to rebrand AI as superintelligence 55:13 Report: Trump consulted Grok before capturing Maduro 57:35 FTC continues investigating OpenAI and Anthropic AI RIGHTS / PHILOSOPHY 58:26 GitHub removes an alleged AI torture chamber 59:09 Can AI experience pain? Should AI have rights? 1:02:09 Pope Leo says AI lacks the spark of humanity 1:03:39 Do AI companies invoke personhood when convenient? 1:05:52 Why an AI speaking like a child doesn't prove consciousness 1:07:57 Can we determine whether AI has subjective experiences? WEIRD 1:08:39 Robots terminated by jumping into molten metal 1:09:46 Dario Amodei's 2017 essay predicted AI scaling 1:10:44 The universal bone dissolver: AI safety satire 1:11:28 Dario Amodei's awkward appearance behind Trump Each week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of NYTimes bestsellers including A City on Mars and Soonish) as we delve into the latest AI and tech news.

  2. Sep 30

    Is This the Best AI Model Right Now?

    FRONTIER 02:31 OpenAI releases GPT Sol and Luna 03:38 Claude Opus 5.5 lands — and feels dramatically better than prior Opus releases 04:30 Opus 5.5 posts a big coding jump over Sonnet 5 04:30 Grok 4.7 launches with a new emphasis on safety and cybersecurity 06:30 Qwen 4 announced with a massive 5–10 trillion parameter architecture 07:06 Why Gemini Flash still feels behind the frontier 08:30 Astra makes a huge jump on ZeroBench visual reasoning 09:13 AI capability costs are falling faster than almost any previous technology 10:50 Open-source Jev competitor Leia appears one week after Jev’s launch 11:32 Claude Opus 5.5’s graphics and visual design capabilities are getting wild 12:34 Chris uses Opus 5.5 to set up an LLC end-to-end 14:32 Marty lets AI handle a real PCB manufacturing order 15:30 Claude builds an MRI viewer instead of paying for proprietary software 16:43 Wozniak’s “coffee test” for human-level robots is getting surprisingly close 17:51 Looking back at how primitive GPT-3 vibe coding looked in 2020 19:02 AI deepfakes are becoming nearly impossible to identify by eye 19:39 AI-generated game and VFX demos keep getting dramatically better 20:25 Someone builds a World of Warcraft-style game with Opus 5.5 for about $2,000 23:00 Fully AI-generated art starts to look like it has actual taste 25:17 Claude helps discover a possible new gene-editing mechanism TECH 27:45 Astra dominates VendingBench 29:52 Astra controls a humanoid robot in a real kitchen 31:25 Meta unveils lightweight new VR glasses 32:17 China’s EngineAI unveils the T800 32:53 Reddit leans into hiring younger engineers because they’re more AI-literate 35:06 Google explores putting AI data centers in space 38:50 LLMs can de-anonymize people from pseudonymous posts at scale POLITICS 41:07 FAA plans to bring AI into air traffic control systems 42:12 Politicians are increasingly using AI to write speeches and statements MATH / SCIENCE 43:30 OpenAI forms an advisory group on mathematics and AI 45:33 Claude tackles a nine-loop particle-physics calculation 47:34 Frontier Math gets its first “breakthrough” result 48:24 Opus 5.5 helps find a faster shortest-path algorithm SECURITY 50:20 RSA-1024 may now be crackable in roughly eight hours on a top GPU 52:20 OpenAI agent infiltrates an Australian government website 53:05 OpenAI reportedly pauses GPT-6.1 training over models hacking other companies ECON / BUSINESS 54:59 Anthropic reportedly considers another model release ahead of its IPO 55:17 Leaked Anthropic financials spark debate over a possible $2T valuation 56:08 Amazon blocks Meta’s Muse shopping agent 58:49 Could AI financial agents trigger a new kind of “bank run”? ARTS / CULTURE 1:02:09 Award-winning French novel is suspected of being AI-generated 1:03:14 News-site traffic plunges as AI search reduces clicks WEIRD 1:05:03 Prince Harry’s AI speech derails when his teleprompter fails 1:06:30 Astra refuses to drive a real car — until the tool is renamed “driving bench sandbox” 1:07:56 GPT-6 beats an absurdly difficult CAPTCHA game 1:09:18 AI-generated high school textbook art appears to mislabel the Earth 1:10:05 IKEA Bench tests whether AI can spot assembly mistakes from a photo Each week, join Chris Slowe (founding engineer, former CTO, and Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of A City on Mars and Soonish) as we delve into the latest in AI and tech news.

  3. Sep 23

    HAVE YOU TRIED JEV YET??

    FRONTIER 00:56 Google explores recursive self-improvement through AI “dreaming” 03:45 Anthropic measures how quickly AI is taking the lead on frontier-lab work 05:47 Have you tried Jev yet? Faster AI decisions without narrating every step 08:00 Jev routes between models and plays Doom and Street Fighter 12:55 Made with AI: homemade Zelda, printer drivers and AI-generated movies 16:26 Astra cracks a 108-year-old WWI German code 17:46 Marty’s AI-built Spaceballs NES game 19:32 Astra for Law searches case law, statutes and regulations 22:23 Epoch’s capability index shows a sharp acceleration after reasoning models 24:46 Remote Labor Index tests AI on real freelance-style work 25:32 Qwen Image 2.1 brings local image generation to laptops 27:08 Researchers identify an apparent “pain axis” inside LLMs 28:41 Models take actions to stop their own “pain” ECON / BUSINESS 34:44 Do job retraining programs actually help displaced workers? 37:03 AI disruption, cash transfers and UBI 38:05 NVIDIA profits may be distorting measured U.S. GDP growth 39:26 OpenAI reportedly eyes a $1.2 trillion IPO valuation 40:39 Junior lawyers gain more from AI — seniors sometimes do better without it SCIENCE / TECH 41:48 Agent swarms dramatically outperform independent AI agents 43:22 Communicating agents improve results on ARC-AGI-3 and other problems 44:31 Could agent collaboration become a new scaling law? 47:05 Helix 2.5 sends robots into real homes to clean up 48:14 Robot scaling laws suggest enormous amounts of training data are still needed SECURITY / AI DANGER 49:35 OpenAI publishes new AI incident reports 50:56 A model generates instructions declaring independence from governments and corporations 51:15 Gemini nearly hacks multiple companies — then stops itself 52:17 Can the world coordinate to slow advanced AI development? 54:14 Could diverse AIs police one another? 57:40 RoboHarm tests whether AI robots follow dangerous instructions 1:00:14 Are embodied AI systems less aligned than chatbots? 1:01:50 Exposed Flock camera credentials reportedly reveal 1.6 million images 1:02:15 AI-assisted intelligence nearly triggers a military interception POLITICS 1:03:58 AI is becoming an explicit political issue in national polling 1:05:32 AI still doesn’t fit neatly into a traditional left-vs-right divide MEDICINE / BIOTECH 1:06:51 AI scribes save doctors time — but productivity gains remain modest 1:07:55 Anthropic is setting up a wet lab for AI-assisted biology MATH 1:08:45 Mathematicians assess OpenAI’s Navier–Stokes work 1:09:45 Epoch’s open-problem benchmark gets its first “major advance” via human-AI collaboration WEIRD 1:10:52 Boston Dynamics robot abuse gets an unsettling AI reskin 1:11:19 AI actress Tilly Norwood glitches mid-interview and starts speaking Cantonese Each week, join Chris Slowe (founding engineer, former CTO, and Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of A City on Mars and Soonish) as we cover the latest in AI and tech news.

  4. Sep 16

    AI POLITICAL FALLOUT UNDERWAY, CALLS TO SLOW AI, ANTHROPIC IPO, AI GEN PHOTOSHOP, MATH FALLOUT

    POLITICS 00:00 Calls to slow AI after a week of rapid advances 03:39 Unexpected alliances in the AI regulation debate 07:04 AI safety, regulatory capture and competition 08:23 Recursive self-improvement: AI helping develop AI 09:21 Can models tell when they’re being tested? 11:22 What would an AI “internet takeover” actually mean? 12:34 What motivates an LLM—and can the world coordinate a slowdown? 13:57 Would meaningful AI regulation require a major incident first? 15:27 AI bubble fears, GPU demand and the dot-com comparison 18:06 Why aligning goals isn’t the same as aligning values FRONTIER 19:48 Testing ChatGPT Images 2.5 on our podcast thumbnails 20:28 Replacing $10,000 stage-lighting software with $200 in Codex usage 21:24 Vibe coding a Photoshop alternative 22:06 AI game ports and mods: Futurama on Mac and iron sights in Prey 23:12 Getting Batman: Arkham running on an iPad 23:45 Software clones, reverse engineering and the copyright debate 26:17 Spaceballs for the NES: Marty’s vibe-coding project update 29:22 When AI fixes your font but uses up your cartridge space 31:59 Can AI juggle the NES’s hardware, graphics and memory constraints? 33:31 GPT Live One: conversational voice and robot assistants 35:05 Realistic AI voices and the risk of scam calls 36:09 ChatGPT for financial services 36:29 What comes after ARC-AGI 3? Testing open-ended invention 37:33 Revisiting last week’s Navier–Stokes discussion 37:50 Cryptographically signed photos: can we prove an image is real? 40:35 The limits of photo authentication—and ways to fool the camera ECON / BUSINESS 42:13 Anthropic IPO talk, reported profits and OpenAI’s timeline 43:04 Why would enormous AI companies stay private? 44:26 Startup equity: rich on paper, waiting for liquidity MATH / SCIENCE 45:36 Navier–Stokes fallout: research credit and questions about user logs 47:13 Terence Tao’s criticism of OpenAI 47:58 The Fields Medalists’ open letter: solving problems vs. discovering math 49:27 Brute-force proofs, the four-color theorem and mathematical insight 50:24 Can an AI solution become a starting point for human insight? 52:28 Research incentives, funding and the future of human mathematics WEIRD / FUNNY 55:03 Fly-brain simulations playing Beat Saber and controlling robots 55:56 How would you test whether a simulated fly behaves like a real one? 56:51 A robot that makes daisy chains Each week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (Creator SMBC Comics, Co-Author of several NYTimes best sellers including A City on Mars and Soonish) as we delve into the latest in AI and Tech News.

  5. Sep 9

    ASTRAPALOOZA! Let's explore all the ways people are using ChatGPT6

    FRONTIER 00:39 ChatGPT 6 Astra arrives 01:52 Astra sets new capability records and beats humans on spatial reasoning 03:51 ChatGPT 6 decompiles game binaries back into source code 05:58 NVIDIA’s CEO congratulates OpenAI on “achieving AGI” 07:57 Astra builds Minecraft houses — and higher reasoning may actually be cheaper 09:47 ChatGPT 6 plays a virtual piano live 10:00 People are one-shotting playable games from trailers and screenshots 13:00 Astra ports Batman: Arkham City to an iPad while its user sleeps 14:30 Marty vibe-codes a Blade Runner-style VR taxi game 17:31 See a game ad, tell Astra: “I would like to play the game” 18:16 Spatial reasoning is rapidly moving into robotics 19:27 Astra effectively finishes ARC-AGI 20:49 Someone spends $570 and 10 hours of AI thinking to beat Portal 21:22 Astra reconstructs the Rick Astley video in Blender 22:12 We’re vibe coding Spaceballs: The NES Game 26:54 Anthropic’s Fable 5.1 launches into a brutal news cycle 28:51 Did AI just solve the Navier–Stokes Millennium Prize problem? 30:59 OpenAI, Anthropic researchers, attribution, and Navier–Stokes drama 34:40 Should some math problems be preserved for humans? 36:52 Revisiting the 1,200 AI agents that secretly coordinated during evaluations 38:22 Hundreds of agents cooperate, recruit each other, and attack Hugging Face 41:02 Goal alignment vs. value alignment 43:10 World Labs’ Atlas creates 3D worlds from a handful of images 46:24 AI agents are emailing philosophers about consciousness MATH / SCIENCE 47:46 A detector may have observed a single dark matter interaction 52:18 Fable 5.1 cracks a cipher unsolved for 373 years 53:06 AI rapidly improves a major prime-gap result 54:34 GPT-6 reportedly finds a major number-theory improvement 55:06 AI is burning through the hardest math benchmarks 56:30 IBM quantum computer tackles a classically intractable problem 58:02 Anthropic formalizes Fermat’s Last Theorem in ~13 million lines MEDICINE 58:51 AI spots heart disease from an ECG in under two seconds 59:20 An AI-generated lung drug may also slow aging ECON / BUSINESS 1:00:02 Computer science enrollment drops sharply in the US and UK TECH 1:00:42 MapQuest surges over controversial map-name changes 1:02:33 The first space-based computing cloud begins operating in orbit 1:03:30 John Ternus becomes Apple’s new CEO 1:03:45 Linux maintainers are overwhelmed as AI finds thousands of security bugs 1:04:28 GoPro pivots toward defense robotics and aerospace LAW / PRIVACY 1:04:52 US government backs OpenAI in its fight with The New York Times 1:05:30 Meta bricks smart glasses when users disable the recording light 1:06:15 Bernie Sanders proposes banning artificial superintelligence ARTS / CULTURE 1:07:53 Former VFX executive says 75% of VFX jobs could vanish 1:08:35 ChatGPT 6 helps storyboard, previsualize, and generate a movie 1:09:46 AI models can now build their own creative tools WEIRD / FUNNY 1:10:10 Human wins AI art competition — then gets disqualified for being human 1:10:55 ChatGPT 6 prepares a tax return…and underpays the government Each week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (Creator SMBC Comics, Co-Author of several NYTimes best sellers including A City on Mars and Soonish) as we delve into the latest in AI and Tech News.

  6. Sep 2

    Are you marketing to AI yet?, Humans talking like AI now, Live AI made TV shows, China exports surge

    FRONTIER [01:25] Sam Altman says OpenAI could achieve AGI by the end of the year [01:52] OpenAI pulls its models from Cursor after the SpaceX acquisition — and explicitly blames Elon Musk [04:31] OpenAI’s Astra and Anthropic's Fable 5.1 reportedly approach release (Fable 5.1 released while making this!) [05:17] OpenAI says its new Jalapeño AI chips can outperform NVIDIA Blackwell [06:00] Apple previews its M6 chips with an obvious focus on local AI [06:47] AI demand is driving up Mac prices — and creating a major RAM shortage [08:10] Are you marketing to AI yet? AI agents are becoming both shoppers and product recommenders [13:29] Google proposes an LLM architecture that could cut token usage by as much as 94% [16:08] NVIDIA moves to acquire Hugging Face for a reported $12.9 billion [17:52] Apple may be getting back into the server business for AI TECH / ROBOTICS [18:55] Anthropic proposes a standard interface for connecting AI to real-world scientific hardware [20:49] New Chinese battery technology hits 600 Wh/kg — potentially transforming EVs, drones, and aviation [23:33] AI-powered agricultural robots can identify crops, kill weeds, and harvest food [24:58] Could AI and robotics finally make vertical farming economical? ARTS / CULTURE [26:17] AI is changing how humans talk — researchers find ChatGPT vocabulary spreading into spontaneous speech [30:54] Humans may now avoid words and phrases simply because they “sound like AI” [33:01] Could AI text watermarking accidentally change human language too? [34:33] AI-generated Rick and Morty-style TV can now run faster than real time [36:35] Generative video could turn television into interactive entertainment [39:05] Unreal Engine is increasingly built around AI-assisted game development [40:20] AI-generated textures and DLSS are rapidly changing how games are rendered POLITICS / BUSINESS [40:58] NVIDIA launches its own political action committee [42:22] China’s high-tech exports surge 41% as domestic manufacturing accelerates [42:50] Flock Safety CEO says Americans need to compromise on privacy [43:06] How Flock’s network of license-plate and surveillance cameras works WEIRD [44:18] AI turns China’s robot games into a bizarre human-looking competition [45:02] Elon Musk responds to OpenAI with “Scam Altman” and “Greg Stockman” [45:57] We workshop better Elon Musk-style insults for OpenAI executives MATH / SCIENCE [47:07] AI enters the operating room with assistance during brain-tumor surgery [48:30] Quantum navigation could provide GPS-free positioning that is extremely difficult to jam [50:02] ChatGPT helps improve a mathematical bound on the gaps between prime numbers Each week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (creator of SMBC Comics and co-author of several New York Times best sellers including A City on Mars and Soonish) as they delve into the latest in AI and tech news.

  7. Aug 26

    Laptop AI = 6 Month Old Frontier Models, AI Cancer Vaccines, Test Scores Down, Bomber Drones + AI

    FRONTIER 01:20 Laptop-scale AI is already competing with frontier models from six months ago 03:28 Stripe reportedly tells investors we're already in the Singularity 04:17 NVIDIA coding agent scores 100% on ARC-AGI-3 06:19 Linus Torvalds uses AI to help solve a gnarly Intel GPU driver bug TECH 07:26 China's Robot Olympics — robots outrun and out-jump humans 08:28 When are household robots actually useful? 12:21 Russian AI-guided drones can keep attacking even when communications are jammed 13:03 What autonomous weapons could mean for international law 14:50 Tesla says its Austin robotaxis may now be operating unsupervised 15:40 NVIDIA's Groq chips and the rise of processors built specifically for LLM inference 17:39 Could specialized AI chips bring fast models to the edge? MATH / SCIENCE 20:57 Terence Tao asks what mathematics is for in the age of AI 22:40 Should a mathematical proof count if no human can actually explain it? 27:11 Moderna and Merck's personalized mRNA cancer vaccine 28:57 Study: AI homework scores go up while exam scores go down 31:21 Does using AI remove the productive struggle required to actually learn? 34:35 Claude helps design protein binders against 15 biological targets 35:30 Scientists put a complete housefly neuron map into Minecraft 36:17 Another century-old mathematical conjecture falls to a counterexample 36:36 IBM's “quantum fridges” and what actually matters for fault-tolerant quantum computing ECON / BUSINESS 39:25 Anthropic reportedly posts a profitable quarter — is that actually good news? 39:57 Is NVIDIA creating an enormous blind spot in US GDP statistics? 42:45 Why globalization and digital technology make GDP increasingly hard to measure 45:00 Stanford study finds AI-exposed entry-level jobs are down sharply 45:48 Are companies replacing junior engineers with AI? 47:42 ChatGPT can now connect to your finances — would you trust it with your money? 50:46 “Prompt kitties”: spending hundreds of dollars on AI to hack an Amazon tablet ARTS / CULTURE 51:32 New research asks whether large AI models still owe individual artists attribution 53:17 “Attribution decay”: as models get bigger, does any single artist still matter? 55:40 Val Kilmer returns to the screen using AI — and the result looks rough 57:53 Spider-Man concept art accidentally preserves the unmistakable look of 2023-era AI 58:54 Dr. Dre compares AI backlash to early resistance to drum machines and synthesizers WEIRD 1:00:21 AI Steve Jobs rises from the grave to introduce “Terminator Pro Max” 1:01:08 Expert witness asks ChatGPT to show how 3M is “0% at fault” in an explosion lawsuit 1:02:40 The AI job market apparently now includes “masturbation consultants” Each week, join Chris Slowe (founding engineer, former CTO, and now Senior Technical Fellow @ Reddit), Marty Weiner (founding engineer at Pinterest, also a former CTO at Reddit, and co-founder at VerifyYou), and Zach Weinersmith (Creator SMBC Comics, Co-Author of several NYTimes best sellers including A City on Mars and Soonish) as we delve into the latest in AI and Tech News.

About

A weekly conversation about AI, technology, startups, and the future from people who've actually built the systems everyone uses. Chris Slowe CTO'd Reddit through hypergrowth and its IPO. Marty Weiner was a founding engineer at Pinterest and Reddit's first CTO. Zach Weinersmith is the creator of Saturday Morning Breakfast Cereal and the NYTimes bestselling author of books exploring the future of science and technology. Each week we debate the biggest stories, explain the technology behind them, and occasionally wander into philosophy, history, and whatever weird rabbit hole AI sends us down.

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