Unsee Podcast

Leonard Pastrana, PharmD
  • 5.0 (1)
  • Medicine

Some moments change how you see medicine forever. Once you see them, you can't unsee them. Hosted by pharmacist Leonard Pastrana, PharmD, this podcast goes inside the private conversations happening at the leading edge of clinical longevity medicine. It features physicians, scientists, and founders who are seeing things in their patients that the textbooks haven't caught up to yet. Too often, "show me the data" is where the conversation ends. Here, it's where it begins. Each episode explores the gap between what we know for sure, what doctors see in practice every day, and the uncertainty in between. You'll hear how the best clinicians think, question, and make reasonable decisions when definitive proof doesn't exist yet. Longevity medicine isn't a new set of rules. It's the evolution of medicine: improving how well you live and how long you live, at the same time. If you've ever felt like there has to be a better way, these are the conversations for you. For educational purposes only. Not medical advice.

Episodes

  1. 2d ago ·  Video

    The Nurse Practitioner Who Says Women's Health Is About to Change

    Is our healthcare system ready for menopause? Nurse practitioner Lexi Yoo says “definitely not,” and she’s building what comes next. Too many women in perimenopause and menopause walk out of their doctor’s office with a prescription for Ambien or Lexapro and no real answers. Lexi Yoo hears that story every week. She’s a nurse practitioner with a foundation in functional and longevity medicine. She’s also going through this stage of life herself, and she believes her generation will change what menopause looks like for decades to come. In this episode of the Unsee Podcast, host Leonard Pastrana, PharmD, talks with Lexi about her path from pediatric trauma care to functional medicine. They cover how she grew one practice into two locations with about 3,000 patients, how she uses peptides alongside hormone therapy, and why medical education takes decades to catch up. Lexi also shares what nurse practitioners need to know about scope of practice and working with physicians, how patient education improves outcomes, and the risks of getting health advice from social media. In this episode: -Why so many women feel unheard in perimenopause and menopause care -How hormone optimization and peptides fit into a women’s health practice -Leaving traditional medicine and scaling a functional medicine practice -Scope of practice, mentorship, and collaboration between NPs and physicians -Social media, AI, and the double-edged sword of online health information Chapters 00:00 Introduction 01:48 Lexi Yoo's Path: From Pediatric Trauma NP to Functional Medicine 04:29 Bariatrics, Weight Loss & Discovering Functional Medicine 07:14 Leaving Traditional Medicine to Start Her Own Practice 08:04 Scaling to 2 Locations & 3,000 Patients 09:33 How She Started Using Peptides 11:59 Hormone Therapy vs. Peptides: What Peptides Add 13:05 Living What You Teach in Longevity Medicine 15:16 Why Sales Isn't a Dirty Word in Medicine 17:58 What Drives Her Now 20:03 Why Teaching Makes You a Better Clinician 22:09 Patient Education That Improves Outcomes 25:26 Why She Focuses on Perimenopause & Menopause 27:21 How Each Generation Approaches Menopause 28:20 Why Medical Schools Are Decades Behind 29:11 Nurse Practitioner Scope of Practice & Working With Physicians 34:16 Mentorship & Investing in Your Education 37:53 Building a Clinic Culture Where No Question Is Stupid 40:33 Bringing Your Team to Medical Conferences 46:29 Her Upcoming Book on Perimenopause 47:50 Social Media, AI & Online Health Misinformation 49:23 Final Thoughts Episode Links Follow Lexi: https://www.instagram.com/lexiyoonp  Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic Learn more about the CALM conference :  https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic Follow Leonard on Instagram: https://www.instagram.com/leonardpastrana

  2. Nov 3 ·  Video

    Who’s Really Making Your Peptides?

    How many doctors are selling research peptides to their patients without realizing it? Pharmacist and compounding pharmacy owner Dr. Franck Kacou joins Leonard Pastrana to break down one of the most misunderstood issues in peptide therapy: the difference between peptides compounded by a licensed pharmacy and products labeled "for research use only." Franck has spent over a decade running a compounding pharmacy now licensed in multiple states, and he's watched peptides go from a physician-led niche to what he calls "the social media economy." In this conversation, he and Leonard get into: • Research vs. compounded peptides, and why the raw ingredient makes all the difference • Why research peptides are so cheap, and what that price is really telling you • How physicians unknowingly buy and sell research peptides to their patients • Why a certificate of analysis (C of A) doesn't tell you as much as you think • How to verify you're actually buying from a licensed 503A or 503B pharmacy • The GLP-1 shortage and how it changed the way physicians buy medications • The FDA Pharmacy Compounding Advisory Committee peptide vote, and what it could mean for compounded peptides • The growing push to bypass physicians with direct-to-consumer models Franck also shares how burning out in traditional retail pharmacy led him to functional and longevity medicine, and the moment he couldn't unsee. This episode is for educational purposes only and is not medical advice. An FDA advisory committee recommendation is not FDA approval. Talk to your licensed healthcare provider before starting any peptide or medication. Chapters 00:00 Introduction 02:39 Inside a Multi-State Compounding Pharmacy 03:25 How BPC-157 Started the Peptide Boom 05:35 Research Peptides vs. Compounded Peptides 13:58 Why Research Peptides Are So Cheap 16:39 How to Verify a Legit 503A or 503B Pharmacy 20:00 503A vs. 503B, GLP-1 Shortage & State Crackdowns 24:57 Retatrutide & the GLP-1 Black Market 28:02 Can You Trust a Certificate of Analysis (C of A)? 34:21 The Future of Peptide Therapy & Liability 40:48 FDA Peptide Vote Explained (PCAC) 44:48 Why Doctors Are Being Bypassed 52:37 Why Every Doctor Needs to Understand Peptides 55:15 From Pharmacy Burnout to Longevity Medicine Connect with Franck: https://www.linkedin.com/in/franck-kacou-pharm-d-mba/ Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic Learn more about the CALM conference :  https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic Follow Leonard on Instagram: https://www.instagram.com/leonardpastrana

  3. Oct 27 ·  Video

    What your patients say about you while you’re not in the room

    Two physicians. Same training, same certifications, same protocols. One has a waitlist. The other is struggling to fill the schedule. The difference usually isn't the medicine. It's the brand. Leonard Pastrana, PharmD, sits down with brand strategist Kelly Binnings, former Chief Brand Officer at nuBioAge, now leading ecosystem and strategic partnerships, to break down what brand actually means for physicians moving into cash-based, relationship-driven care. It's not the logo or the website. It's how your team answers the phone, how patients are treated when leadership isn't around, and whether people experience what you say you stand for. In this episode: → The real difference between brand and marketing → Why physicians are now small business owners who have to earn trust → What it means to "operationalize" a brand inside your practice → Why consistency feels boring and why it works → Word of mouth as the most powerful growth channel in healthcare → How you measure brand when there's no clean KPI (value, consistency, and authenticity signals) → Neuroaesthetics: how the brain and body respond to brand experiences → Phenomenology and why subjective experience still matters in data-driven medicine → How the room design at CALM changed how a skeptical physician received the content → Masterminds, community, and finding your tribe → Kelly's book, Breakout Creative You can't fake a brand, at least not for long. Get clear on your North Star, surround yourself with people who share it, and the brand takes care of itself. — Follow Kelly:  https://www.instagram.com/kbinnings/  Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic Learn more about the CALM conference :  https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic Follow Leonard on Instagram: https://www.instagram.com/leonardpastrana  This content is for educational purposes only and is not medical advice. 00:00 Introduction 00:44 Opening 02:27 From print designer to brand strategist 03:12 Brand vs. marketing 04:15 Building nuBioAge's brand from the ground up 05:56 What branding actually means 07:52 Why physicians need a brand in cash-based medicine 10:39 Operationalizing your brand 13:51 Consistency is the whole game 16:01 Same training, different results: the patient experience 18:53 Word of mouth and building CALM 21:17 Partnerships built on a shared mission 24:03 Why brand is hard to put a dollar amount on 25:45 Live events in the age of AI 28:03 Neuroaesthetics and measuring brand through signals 30:42 Phenomenology: subjective vs. objective data in medicine 33:32 Why a skeptic felt different walking into CALM 34:51 The Ritz-Carlton standard for medical events 35:49 How great events quietly build community 37:52 Bringing marketing-conference energy to medical education 39:06 Becoming a category of one 39:51 Why masterminds work 42:49 Kelly's book: Breakout Creative 44:01 Leonard's biggest brand lesson: you can't fake it 46:44 Wrap-up

  4. Oct 20 ·  Video

    Who’s Really Deciding Your Care? A Chief Medical Officer Explains

    Some moments change how you see medicine forever. Once you see them, you can't unsee them. For Dr. Haleem Mohammed, known as Dr. Hal, one of those moments happened at home. He was a chief medical officer managing thousands of employees, and he had reached 255 pounds. His wife, also a physician, asked him a question he couldn't ignore: would he be around after they had a baby? He resigned, rebuilt how he lived, and rebuilt how he practiced. Today he's a board-certified internist, Chief Medical Officer of Gameday Men's Health, runs his own concierge practice, and serves on the FDA's Pharmacy Compounding Advisory Committee. Leonard and Dr. Hal go from Wall Street to the FDA hearing room. They talk about how insurance shapes what doctors can and can't do, and why he tells some men they don't need testosterone. They cover what a network of hundreds of clinics reveals that a single practice can't, and what it was like to push back during a committee meeting on the future of compounded peptides. In this episode: -His path from stockbroker to chief medical officer -The 255-pound wake-up call that changed his life and his medicine -How insurance shapes what doctors are allowed to do -The difference between a low testosterone number and testosterone deficiency -His advice for doctors who want out of the insurance model -What the FDA advisory committee actually does, and what it doesn't -What drives him now This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care. Follow Dr. Hal on Instagram: https://www.instagram.com/healthwithdrhal  Learn More About Gameday Men's Health: https://gamedaymenshealth.com/ Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic Learn more about the CALM conference :  https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic Follow Leonard on Instagram: https://www.instagram.com/leonardpastrana Chapters  00:00 Introduction  00:58 From Wall Street to Medicine  10:07 Building Gameday Men's Health  12:35 Insurance Medicine vs. Whole-Patient Care  15:43 Who Your Insurance Company Really Works For  16:34 What Hundreds of Clinics Reveal  18:39 "You Don't Need Testosterone"  19:52 The Problem With Some HRT Clinics and Med Spas  22:36 "My Goal Is to Not Have Any Patients"  24:11 Advice for Doctors Stuck in the Insurance Model  25:37 Collaboration Over Competition  27:41 Separating Signal From Noise  31:01 Why He Still Sees Patients  31:28 Inside the FDA Compounding Committee  33:39 Old Guard vs. New Guard  35:04 "I Think We Did the Right Thing That Day"  36:33 What Drives Him  39:58 Where to Find Dr. Hal

  5. Oct 13 ·  Video

    Why Real-World Data Belongs in the Peptide Debate

    Some moments change how you see medicine forever. Once you see them, you can’t unsee them. Dr. Kris Wusterhausen was doing everything he’d been taught. He was running a county clinic, he was burned out, his weight had climbed to 199 pounds, and his A1C had reached 6.2. Fixing his own health changed how he practiced medicine. In his words, it took him from a widely accepted family doctor to “the kooky doctor in town.” Years later, some of the doctors who called him kooky became his patients. Today he’s a board-certified family physician and founder of The Resurge Clinic in Weatherford, Texas. He trains physicians in hormone and peptide therapy and serves on the FDA’s Pharmacy Compounding Advisory Committee. Leonard and Dr. Kris go inside the committee meeting where BPC-157 and other peptides were reviewed. They cover what the committee was actually asked to decide, and why real-world clinical data deserves a seat at the table. Dr. Kris also shares the financial reality of leaving traditional medicine, his keep-it-simple approach to hormones and peptides, and why he brings his entire staff to medical conferences. In this episode: -The burnout and health crisis that pushed him out of traditional practice -The financial reality of transitioning to a new practice model -From “kooky doctor” to accepted: how the field has shifted -Inside the FDA Pharmacy Compounding Advisory Committee’s peptide review -Why the vote was about compounding safety, not FDA approval -Why great clinicians rely on a handful of peptides, not twenty -Nutrition, movement, and the 80/20 approach to longevity -Why every person in a practice should understand patient care Learn More About Dr Kris: The Resurge Clinic: https://www.theresurgeclinic.com/?utm_source=podcast&utm_medium=organic Follow Dr. Kris on Instagram: https://www.instagram.com/drkriswusterhausen/?utm_source=podcast&utm_medium=organic Learn more about nuBioAge: https://nubioage.com/register/?utm_source=podcast&utm_medium=organic Learn more about the CALM conference :  https://calm.nubioage.com/?utm_source=podcast&utm_medium=organic Follow Leonard on Instagram: https://www.instagram.com/leonardpastrana This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care. Chapters  00:00 Introduction  00:46 Introducing Dr. Kris  02:10 Burned Out at the County Clinic  04:41 Finding a Different Model of Medicine  06:19 The Hard Truth About Transitioning Practices  07:43 Why Doctors Should Share Their Failures  10:23 How He Stays Ahead of the Curve  13:58 From “Kooky Doctor” to Mainstream  17:10 Better Tools, Same Basics  18:50 Why Doctors Can’t Ignore Social Media  23:50 Too Pharma for the Gym Bros  25:05 Getting the Call From the FDA  28:23 Inside the Room: BPC-157 and the Vote  30:57 Real-World Data vs. the Regulatory Process  32:22 Best Intentions on Both Sides  33:22 Longevity Without the Neurosis  38:29 Why You Don’t Need 20 Peptides  39:57 Foundations First, Then Peptides  41:44 What Patients Actually Care About  43:43 Where Traditional Medicine Lost Its Way  45:44 Health as a Smart Bet  48:11 Ask Patients What They’ll Actually Do  49:23 Why He Brings His Whole Staff to Conferences  53:33 Building Your Community  55:13 Closing Thoughts peptides, peptide therapy, BPC-157, FDA peptides, FDA advisory committee, Pharmacy Compounding Advisory Committee, 503A compounding, compounded peptides, longevity medicine, age management medicine, hormone replacement therapy, BHRT, physician burnout, osteopathic medicine, functional medicine, real-world evidence, preventive medicine, Dr. Kris Wusterhausen, The Resurge Clinic, Leonard Pastrana, Unsee Podcast

  6. Oct 6 ·  Video

    Why "Show Me the Data" Should Be the Beginning

    Some moments change how you see medicine forever. Once you see them, you can't unsee them. In this first episode Leonard Pastrana, Pharm D shares the "unseen moments" that reshaped his view of healthcare. They include a hospital committee that chose a treatment based on cost instead of what was best for the patient, and his wife's years of recurring diverticulitis flares that specialist after specialist couldn't explain. It took a physician willing to look beyond the guidelines to finally find what everyone else had missed.   After working in retail and hospital pharmacy, and then spending years creating education alongside leading physicians and scientists in clinical longevity medicine, he's had thousands of private conversations with doctors who practice in the gap between what's proven, what they see in patients every day, and what we're still figuring out.   This show brings those conversations into the open. You'll hear from physicians, scientists, and founders who treat "show me the data" as the start of the conversation, not the end.   In this episode: - What an "unseen moment" is, and why it happens so often in healthcare - Longevity medicine defined: improving health span and lifespan together - Why earlier diagnostics are creating new uncertainty in medicine - The personal story behind the show   This podcast is for educational purposes only and is not medical advice. Talk with your healthcare provider before making changes to your care.

  • 6 Episodes

About

Some moments change how you see medicine forever. Once you see them, you can't unsee them. Hosted by pharmacist Leonard Pastrana, PharmD, this podcast goes inside the private conversations happening at the leading edge of clinical longevity medicine. It features physicians, scientists, and founders who are seeing things in their patients that the textbooks haven't caught up to yet. Too often, "show me the data" is where the conversation ends. Here, it's where it begins. Each episode explores the gap between what we know for sure, what doctors see in practice every day, and the uncertainty in between. You'll hear how the best clinicians think, question, and make reasonable decisions when definitive proof doesn't exist yet. Longevity medicine isn't a new set of rules. It's the evolution of medicine: improving how well you live and how long you live, at the same time. If you've ever felt like there has to be a better way, these are the conversations for you. For educational purposes only. Not medical advice.

Information

  • Creator
    Leonard Pastrana, PharmD
  • Years Active
    2026
  • Episodes
    6
  • Rating
    Clean
  • Copyright
    © Copyright 2026 All rights reserved.
  • Show Website
    Unsee Podcast