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Although guideline-directed medical therapy substantially improves morbidity and mortality in patients with heart failure with reduced ejection fraction (HFrEF), treatments that clearly improve outcomes in those with HF and an EF >40% remain elusive. Unfortunately, the incidence and prevalence of HF are expected to substantially increase in the coming decades.  More evidence and effective treatments for those with HF with preserved ejection fraction are clearly needed.  Enter the EMPEROR-Preserved trial.


Guest Authors:  Gabrielle Givens, PharmD, BCPS and Robert Parker, PharmD


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Continuous glucose monitors (CGMs) are now commonplace, and every clinician should know the basics about who can benefit from CGM use and how to address common questions and problems. 


Authors:  Brianna Patacini, PharmD, BCACP, CDCES and Dawn Fuke, PharmD, BCPS


Special Guest: Jennifer Trujillo, PharmD, BCPS, CDCES, BC-ADM


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Every day, millions suffer from poor sleep that disrupts their lives, and long-term sleep disorders can cause attention deficits, mood disorders, anxiety, and depression. Several prescription treatment options for sleep are available but they often have undesirable side effects and can lead to tolerance and dependency. Thus, a natural product that has been documented to improve sleep with minimal adverse events may be a better choice.


Guest Authors:  Alyssa Korman, PharmD and Nicole Slater, PharmD, BCACP


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There are now over 30 unique therapeutic entities (and countless different products!) to treat hyperglycemia in patients with type 2 diabetes mellitus (T2DM).  While the glucagon-like peptide-1 (GLP-1) receptor agonists improve glycemic control, renal, and cardiovascular outcomes and induce significant weight loss, drugs that target more than one incretin hormone may have even greater therapeutic benefits.


Guest Authors: Nadila Faridi, PharmD and Kathleen Pincus, PharmD, BCPS, BCACP


Special Guest: Diana Isaacs, PharmD, BCPS, BCACP, BC-ADM, CDCES


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WARNING: Patient has a penicillin allergy! Do you want to continue with this cephalexin order?


Although these warnings are commonplace, immunologic cross-reactivity between penicillins and cephalosporins is uncommon. When B-lactams are indicated as first-line therapy for therapy, cephalosporins are often avoided if the patient has a penicillin allergy listed. Would the removal of EHR warnings about potential penicillin allergies when cephalosporins are ordered be helpful or harmful? 


Guest Authors:  Brian Wenger, PharmD and Nora Sharaya, PharmD, BCPS, BCACP, BC-ADM


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There is no consensus regarding the preferred dosage of aspirin in patients with atherosclerotic cardiovascular disease (ASCVD) and this has led to variability in prescribing patterns. This is likely due to the lack of head-to-head trials evaluating different aspirin doses and data weighing the clinical benefits and adverse effects experienced with aspirin. Until now?


Guest Authors: Ivy Nwogu, PharmD and Megan Supple, PharmD, BCACP, CPP


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